公开(公告)号：WO2007041279A3

公开(公告)日：2007-09-27

申请号：PCT/US2006038028

申请日：2006-09-29

申请人： CELL BIOSCIENCES INC S ,  BEARDSLEY TERRY RAYMOND

发明人： BEARDSLEY TERRY RAYMOND

IPC分类号： A61K45/00

CPC分类号： A61K38/1709 ,  A61K38/012

摘要： T4 Immune Stimulating Factor (TISF) selectively induces aberrant T-cells to initiate apoptosis. TISF and peptides that are related to TiSF (TISF peptides) are therefore useful for the treatment of disorders characterized by aberrant production, development, or activity of T- cells or other cells of hematopoietic origin. This invention relates to methods of using TISF or a TISF peptide to treat such conditions, compositions containing TISF or a TISF peptide for use in such treatments, and use of TISF or a TISF peptide for the manufacture of pharmaceuticals .

摘要翻译： T4免疫刺激因子（TISF）选择性诱导异常T细胞引发细胞凋亡。 因此，与TiSF（TISF肽）相关的TISF和肽可用于治疗特征在于T细胞或造血起源的其他细胞异常产生，发育或活性的疾病。 本发明涉及使用TISF或TISF肽来治疗这些病症的方法，含有用于这种治疗的TISF或TISF肽的组合物，以及使用TISF或TISF肽来制造药物。