公开(公告)号：WO2018210345A1

公开(公告)日：2018-11-22

申请号：PCT/CN2018/087547

申请日：2018-05-18

申请人： CHEN, Wen-Shiang

发明人： CHEN, Wen-Shiang ,  KUNG, Yi

IPC分类号： A61M5/178 ,  A61N1/18

CPC分类号： A61M5/19 ,  A61M5/178 ,  A61M2205/0272 ,  A61M2205/3317 ,  A61M2250/00 ,  A61N1/0502 ,  A61N1/18 ,  A61N1/30 ,  A61N1/327

摘要： An apparatus for delivery of an agent into a predetermined tissue of a subject and a method of using the apparatus to deliver an agent into a predetermined tissue are disclosed. The apparatus has a concentric-type needle electrode (1) to enable the cellular uptake of exogenous molecules. The apparatus and method of the invention are easy to use and they overcome the drawbacks of the conventional techniques used in electroporation process, such as electrical safety, tissue damage, and more numbers of required wounds. The apparatus and method of the invention effectively reduce tissue damage, wound numbers, processing steps and working areas.