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    SURFACTANT SYSTEM FOR INCREASING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE
    1.
    发明申请
    SURFACTANT SYSTEM FOR INCREASING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE 审中-公开
    增加牙科组织抗菌剂吸收的表面活性剂体系

    公开(公告)号：WO0230379A2

    公开(公告)日：2002-04-18

    申请号：PCT/US0129608

    申请日：2001-09-21

    Applicant: COLGATE PALMOLIVE CO

    Inventor： LIU XIAOYAN ,  WILLIAMS MALCOLM ,  SUBRAMANYAM RAVI

    IPC: A61K8/34 ,  A61K8/44 ,  A61K8/46 ,  A61Q11/00 ,  A61K7/16

    CPC classification number: A61Q11/00 ,  A61K8/34 ,  A61K8/44 ,  A61K8/463

    Abstract: An oral composition comprising in an orally acceptable vehicle, an effective antiplaque amount of an halogenated diphenyl ether or phenolic antibacterial compound, and an amount of an mixed anionic/zwitterionic surfactant system which is effective to increase the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.

    Abstract translation: 一种口腔用组合物，其在口腔可接受的载体中包含有效抗牙斑量的卤化二苯醚或酚类抗菌化合物和一定量的有效增加抗菌化合物对牙齿组织吸收的混合阴离子/两性离子表面活性剂体系 以增强施用的抗菌化合物的治疗功效。

    DUAL COMPONENT DENTIFRICE FOR REDUCING MOUTH ODORS
    4.
    发明申请
    DUAL COMPONENT DENTIFRICE FOR REDUCING MOUTH ODORS 审中-公开
    减少浑浊气味的双组分干燥剂

    公开(公告)号：WO02053116A2

    公开(公告)日：2002-07-11

    申请号：PCT/US0149004

    申请日：2001-12-19

    Applicant: COLGATE PALMOLIVE CO

    Inventor： SUBRAMANYAM RAVI ,  WILLIAMS MALCOLM ,  GEBRESELASSIE PETROS ,  LIU XIAOYAN ,  ZACCAGNINO ANGELO ,  MASTERS JAMES G

    IPC: A61K8/20 ,  A61K8/27 ,  A61Q11/00 ,  A61K7/16

    CPC classification number: A61Q15/00 ,  A61K8/20 ,  A61K8/27 ,  A61K2800/88 ,  A61Q11/00

    Abstract: A dual component oral composition to suppress oral malodor and provide long lasting breath protection in the oral cavity which comprises a first dentifrice component having a substantially neutral pH and containing a zinc ion releasable compound and a chlorite ion releasable compound, the second dentifrice component having an acid pH, the first and second components being maintained separate from each other until dispensed and combined for application to teeth, the combined components having a pH of no greater than 7.

    Abstract translation: 一种双组分口服组合物，用于抑制口腔恶臭并在口腔中提供持久的呼吸保护，其包含具有基本上中性的pH并含有锌离子可释放化合物和亚氯酸盐离子可释放化合物的第一洁齿剂组分，所述第二洁齿剂组分具有 酸性pH值，第一和第二组分保持彼此分离直到分配并组合以施用于牙齿，组合的组分具有不大于7的pH。

    ORAL CARE COMPOSITION CONTAINING ZINC SALTS AND CALCIUM CARBONATE
    8.
    发明申请
    ORAL CARE COMPOSITION CONTAINING ZINC SALTS AND CALCIUM CARBONATE 审中-公开
    含锌盐和碳酸钙的口腔护理组合物

    公开(公告)号：WO2016077688A2

    公开(公告)日：2016-05-19

    申请号：PCT/US2015060563

    申请日：2015-11-13

    Applicant: COLGATE PALMOLIVE CO

    Inventor： SUBRAMANYAM RAVI ,  JOGUN SUZANNE ,  HASSAN MAHMOUD ,  XU SHAO PENG ,  LEWIS NAVIN ,  HUANG XIAO YI

    IPC: A61K8/27 ,  A61K8/02 ,  A61K8/04 ,  A61K8/19 ,  A61K8/365 ,  A61Q11/00

    CPC classification number: A61K8/27 ,  A61K8/0237 ,  A61K8/042 ,  A61K8/19 ,  A61K8/21 ,  A61K8/25 ,  A61K8/365 ,  A61K8/37 ,  A61Q11/00

    Abstract: The present invention provides an oral care composition comprising: (a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and (b) a second composition comprising a calcium carbonate abrasive; wherein the first composition and/or the second composition further comprises a second zinc compound selected from zinc oxide, zinc carbonate and zinc tartrate; and wherein the oral care composition optionally further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.

    Abstract translation: 本发明提供一种口腔护理组合物，其包含：（a）第一组合物，其包含二氧化硅研磨剂和选自柠檬酸锌，氯化锌，乙酸锌，乳酸锌，水杨酸锌，硫酸锌和硝酸锌的第一锌化合物; 和（b）包含碳酸钙研磨剂的第二组合物; 其中所述第一组合物和/或所述第二组合物进一步包含选自氧化锌，碳酸锌和酒石酸锌的第二锌化合物; 并且其中所述口腔护理组合物任选地进一步包含基于所述口腔护理组合物的总重量为0.1-1.75重量％的牙垢控制剂。

    ETHOXYLATED AND / OR HYDROGENATED OIL ADDUCT
    10.
    发明申请
    ETHOXYLATED AND / OR HYDROGENATED OIL ADDUCT 审中-公开
    乙氧基化和/或加氢油添加剂

    公开(公告)号：WO2009073382A3

    公开(公告)日：2009-07-23

    申请号：PCT/US2008084178

    申请日：2008-11-20

    Applicant: COLGATE PALMOLIVE CO ,  SUBRAMANYAM RAVI ,  MATTAI JAIRAJH ,  POTNIS SHASHANK ,  WU QIANG ,  XU GUOFENG

    Inventor： SUBRAMANYAM RAVI ,  MATTAI JAIRAJH ,  POTNIS SHASHANK ,  WU QIANG ,  XU GUOFENG

    IPC: A61K8/92 ,  A61K8/36 ,  A61Q19/00

    CPC classification number: A61K8/922 ,  A61K8/375 ,  A61Q15/00 ,  A61Q19/007 ,  A61Q19/10 ,  C11C3/00 ,  C11C3/006 ,  C11C3/12 ,  C11D1/74 ,  C11D3/2082 ,  C11D3/2086 ,  C11D3/2093 ,  C11D3/382

    Abstract: A composition of matter comprising an oil adduct synthesized by an oil and an addition material, wherein the oil includes at least one member chosen from an ethoxylated oil, a hydrogenated oil, and an ethoxylated and hydrogenated oil; wherein the average degree of ethoxylation in the ethoxylated (optionally hydrogenated) oil is less than about 10 based on moles of ethylene oxide per mole of oil; wherein the hydrogenated (optionally ethoxylated) oil has an iodine value of less than about 75; wherein the oil is capable of undergoing reaction with the addition material through a hydroxyl group of the oil; and wherein the addition material includes at least one member chosen from carboxylic acid anhydrides, maleic anhydride, dicarboxylic acids, fumaric acid, maleic acid, succinic acid, alpha hydroxy acids, beta hydroxy acids, lactic acid, glycolic acid, lactobionic acid, carnitine, salicylic acid, and (meth)acrylic acid.

    Abstract translation: 一种包含由油和加料合成的油加合物的物质组合物，其中所述油包括选自乙氧基化油，氢化油和乙氧基化氢化油中的至少一种; 其中乙氧基化（任选氢化）油中的平均乙氧基化度基于每摩尔油的环氧乙烷摩尔数小于约10; 其中所述氢化（任选乙氧基化）的油的碘值小于约75; 其中所述油能够通过所述油的羟基与所述添加材料发生反应; 并且其中所述添加材料包括选自羧酸酐，马来酸酐，二羧酸，富马酸，马来酸，琥珀酸，α-羟基酸，β-羟基酸，乳酸，乙醇酸，乳糖酸，肉碱， 水杨酸和（甲基）丙烯酸。

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