公开(公告)号：WO2015061800A2

公开(公告)日：2015-04-30

申请号：PCT/US2014/062469

申请日：2014-10-27

Applicant: COLLINS, Scott Forrest ,  BOLAND, Thomas ,  YANEZ, Maria

Inventor： COLLINS, Scott Forrest ,  BOLAND, Thomas ,  YANEZ, Maria

IPC: A61K35/12

CPC classification number: A61L27/3839 ,  A61F2/12 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2240/004 ,  A61F2310/00371 ,  A61F2310/00377 ,  A61F2310/00383 ,  A61K35/28 ,  A61K35/33 ,  A61K35/35 ,  A61K35/44 ,  A61L27/225 ,  A61L27/227 ,  A61L27/3804 ,  A61L27/3808 ,  A61L27/3834 ,  A61L27/3886 ,  A61L27/52 ,  A61L2430/04 ,  C12N5/0653 ,  C12N5/0697 ,  C12N2502/1352 ,  C12N2502/28 ,  C12N2533/56 ,  C12N2533/76 ,  C12N2535/10 ,  A61K2300/00

Abstract: Tissue engineered constructs and methods for fabricating the disclosed constructs are provided. Some of the disclosed tissue engineered constructs are designed to fill a void in the body due to surgical resection, for example from mastectomy or lumpectomy, wounds and the like. Some disclosed constructs comprise one or more projections designed to mimic the appearance of a structural feature when implanted into a host.

Abstract translation: 提供了用于制造所公开的构建体的组织工程构建体和方法。 一些公开的组织工程构建体被设计成填充由于例如来自乳房切除术或乳房肿瘤切除术，伤口等的手术切除而引起的体内空隙。 一些公开的构建体包含一个或多个突出物，其被设计成当植入宿主中时模仿结构特征的外观。