公开(公告)号：WO2014100831A1

公开(公告)日：2014-06-26

申请号：PCT/US2013/077616

申请日：2013-12-23

Applicant: CORNELL UNIVERSITY

Inventor： WANG, Michelle, D. ,  LIPSON, Michal ,  SOLTANI, Mohammad ,  LIN, Jun ,  SARAF, Summer, N.

IPC: G01N35/08 ,  G01N33/483

CPC classification number: B01L3/502761 ,  B01L3/502715 ,  B01L2200/0668 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/168 ,  B01L2400/0454 ,  B82Y20/00 ,  G02B2006/12159 ,  Y10T436/25375

Abstract: In one implementation, a microfluidic device based on optical trapping of particles is disclosed to include a substrate structured to include a fluidic channel which can carry a fluid having particles; and an optical waveguide loop formed on the substrate to include one or more waveguide sections that reside within the fluidic channel, an input optical port for the optical waveguide to receive an input optical beam, and an optical power splitter coupled to the optical waveguide loop to split the received input optical beam into two counter- propagating optical beams that prorogate in the optical waveguide loop in opposite directions and interfere with each other to form standing optical waves in at least the one or more waveguide sections that reside within the fluidic channel to optically trap particles at or near a surface of the one or more waveguide sections that reside within the fluidic channel. This device further includes an electrically controllable phase control device formed on the substrate and coupled to a location of the optical waveguide loop and operable to control an optical delay experienced by guided light at the coupled location, wherein the electrically controllable phase control device is configured to respond to an electrical control signal to adjust an amount of the optical delay at the coupled location to cause a shift in locations of nodes of each optical standing wave to change trapping locations of the trapped particles in the fluidic channel.

Abstract translation: 在一个实施方案中，公开了基于颗粒的光学捕获的微流体装置，以包括被构造成包括流体通道的基板，所述流体通道可承载具有颗粒的流体; 以及形成在所述衬底上以包括位于所述流体通道内的一个或多个波导部分的光波导环路，用于所述光波导接收输入光束的输入光端口，以及耦合到所述光波导环路的光功率分配器 将接收到的输入光束分成两个反向传播的光束，该光束在相反方向上在光波导环路中分化，并且彼此干涉以在至少位于流体通道内的一个或多个波导部分中形成驻波束，以光学 在位于流体通道内的一个或多个波导部分的表面处或附近捕获颗粒。 该装置还包括形成在基板上的电可控相位控制装置，该电可控相位控制装置耦合到光波导环路的一个位置，并且可操作以控制由耦合位置处的导向光所经历的光学延迟，其中电可控相位控制装置被配置为 响应于电气控制信号以调整耦合位置处的光学延迟的量以引起每个光驻波的节点的位置偏移，以改变在流体通道中捕获的颗粒的捕获位置。