公开(公告)号：WO2021159015A1

公开(公告)日：2021-08-12

申请号：PCT/US2021/016948

申请日：2021-02-05

申请人： CYTOKINETICS, INC.

发明人： ROMERO, Antonio ,  CHANDRA, Aroop ,  EVANS, Christopher Edward ,  SHEN, Minxing

IPC分类号： C07D213/36 ,  C07C275/28 ,  A61P3/00 ,  A61P25/16 ,  A61P29/00 ,  A61P35/00 ,  C07D205/04 ,  C07D207/16 ,  C07D213/81 ,  C07D241/12 ,  C07D295/073 ,  C07D305/08 ,  C07D309/14 ,  C07D331/04 ,  C07D333/08 ,  C07D335/02 ,  C07D491/22 ,  A61K31/17 ,  A61K31/4422

摘要： Provided are compounds of Formula (II) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, and p are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.