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公开(公告)号：WO2023042127A1
公开(公告)日：2023-03-23
申请号：PCT/IB2022/058735
申请日：2022-09-15
发明人： LIU, Chang , IVOSEV, Gordana , ZHANG, Hui
IPC分类号： G06K9/00
摘要： Methods and systems for spectral comparison and quality assessment are disclosed. In one example, a method for assessing quality of a mass spectrum (MS) of a sample is provided. The method comprises: predefining one or more features or attributes indicative of the sample quality with reference to a target compound; and calculating a quality score for the MS with respect to the selected features or attributes.
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公开(公告)号：WO2022172156A1
公开(公告)日：2022-08-18
申请号：PCT/IB2022/051124
申请日：2022-02-08
发明人： COVEY, Thomas R. , LIU, Chang , ZHANG, Hui
IPC分类号： H01J49/04
摘要： A method of sampling an ejection of a sample from a liquid container includes disposing the liquid container adjacent an open port interface. The container includes a sampling port. The open port interface engages with the sampling port. The sample from the liquid container is ejected, through the sampling port, and into the open port interface. The sample is analyzed with a mass spectrometry device.
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公开(公告)号：WO2023047267A1
公开(公告)日：2023-03-30
申请号：PCT/IB2022/058849
申请日：2022-09-19
发明人： IVOSEV, Gordana , LIU, Chang , TATE, Stephen , ZHANG, Hui
IPC分类号： H01J49/00
摘要： A method for performing mass spectrometry (MS) comprises receiving MS data corresponding to a plurality of MS runs, wherein MS data corresponding to an MS run of the plurality of MS runs comprises detected intensities for a plurality of mass over charge ratios (MZ values) during the MS run; finding a recurrent MZ value of the plurality of MZ values, wherein a detected intensity for the recurrent MZ value appears as a recurrent peak in MS data corresponding to a subset of the plurality of MS runs; and the subset of the plurality of MS runs includes at least two MS runs of the plurality of MS runs; and identifying the recurrent MZ value as corresponding to a background ion.
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公开(公告)号：WO2022137172A1
公开(公告)日：2022-06-30
申请号：PCT/IB2021/062200
申请日：2021-12-22
发明人： LIU, Chang , ZHANG, Hui
IPC分类号： H01J49/04
摘要： A method of ejecting a plurality of samples from a well plate includes receiving a first sample intensity prediction associated with a first sample in a first well of the well plate. A second sample intensity prediction associated with a second sample in a second well is also received. The second sample intensity prediction is less than the first sample intensity prediction. An ejection time delay value for a subsequent analysis of the first sample and the second sample is determined, based at least in part on the second sample intensity prediction. Thereafter, the first sample is acoustically ejected from the first well, and the second sample is acoustically ejected from the second well.
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