公开(公告)号：WO2019089147A1

公开(公告)日：2019-05-09

申请号：PCT/US2018/051806

申请日：2018-09-19

申请人： FIBROGEN, INC.

发明人： PORTER, Seth ,  LIPSON, Kenneth E. ,  GORINA de TRAVY, Eduard ,  YU, Kin-Hung Peony

IPC分类号： A61K39/395 ,  A61K45/06 ,  C07K16/22

CPC分类号： C07K16/22 ,  A61K2039/505 ,  A61P11/00 ,  C07K2317/24 ,  A61K2300/00

摘要： The present invention relates to methods and medicaments useful for treating idiopathic pulmonary fibrosis (IPF) by administering an anti-CTGF antibody. In particular, the treatment methods provided avoid toxicities associated with approved therapies and also avoid the attenuation of the efficacy of an anti-CTGF antibody caused by these approved therapies.