公开(公告)号：WO2020243039A1

公开(公告)日：2020-12-03

申请号：PCT/US2020/034450

申请日：2020-05-25

Applicant: GALAXY THERAPEUTICS, INC.

Inventor： PEREIRA, Edgard Luiz Ramos ,  ZAIDAT, Osama O. ,  FOLLMER, Brett ,  WOLFE, Thomas J. ,  ROSQUETA, Arturo ,  BADRUDDIN, Aamir ,  LILLY, Richard

IPC: A61B17/12 ,  A61B17/00 ,  A61F2/00 ,  A61F2/06 ,  A61F2/852 ,  A61F2/86 ,  A61F2/90

Abstract: An apparatus for treating an aneurysm includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and having a distal end, a proximal end, and a longitudinal axis extending between the distal end and the proximal end, the occlusion element configured to be delivered in a collapsed configuration and further configured to expand to an expanded configuration, the occlusion element comprising an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold located at or adjacent the distal end of the occlusion element, the inversion fold defining an inner diameter, the occlusion element further comprising a maximum outer diameter, wherein the inner diameter is between about 35% to about 85% of the maximum outer diameter, and wherein an outer diameter of the occlusion element increases along the longitudinal axis to the maximum outer diameter.

公开(公告)号：WO2022164957A1

公开(公告)日：2022-08-04

申请号：PCT/US2022/013986

申请日：2022-01-27

Applicant: GALAXY THERAPEUTICS, INC.

Inventor： NGO, Tiffany Tran ,  SOLTANIAN, Razmik ,  ZAIDAT, Osama O. ,  PEREIRA, Edgard Luiz Ramos ,  ROSQUETA, Arturo ,  WOLFE, Thomas J. ,  BADRUDDIN, Aamir

IPC: A61B17/12

Abstract: AN apparatus for treating an aneurysm in a blood vessel includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and configured to be delivered in a collapsed configuration through an inner lumen of a delivery catheter, the occlusion element including an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold, wherein at least the outer layer is formed into a first expanded shape including: a smooth outer cylinder configured to engage a wall of an aneurysm throughout a 360° circumference; and a substantially distal- facing surface including one or more heat-formed undulations, the one or more undulations configured to apply a radial force on the wall of the aneurysm.