公开(公告)号：WO2022028726A1

公开(公告)日：2022-02-10

申请号：PCT/EP2020/086367

申请日：2020-12-16

Applicant: GIVAUDAN SA

Inventor： SAJI, Norikazu ,  BARTHOLOMEW, Tracy ,  COCITO ARMANINO, Nicolas

IPC: A61K8/49 ,  A61K8/42 ,  A61K8/365 ,  A61Q11/00 ,  A61K2800/244 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4986

Abstract: A liquid compositions comprising at least one non-natural cooling compound and lactic acid, and the use of said composition in a flavour or fragrance composition.

公开(公告)号：WO2018154102A1

公开(公告)日：2018-08-30

申请号：PCT/EP2018/054633

申请日：2018-02-26

Applicant: GIVAUDAN SA

Inventor： MACMASTER, Angus Peter ,  BARTHOLOMEW, Tracy ,  WATKINS, Stephen, David

IPC: A61Q11/00 ,  A61K8/42 ,  A61K8/49 ,  A61K8/37

CPC classification number: A61Q11/00 ,  A61K8/37 ,  A61K8/42 ,  A61K8/4926 ,  A61K2800/244 ,  A61K2800/49

Abstract: A liquid cooling composition that is a mixture of (N-(4-cyanomethylphenyl) p-menthanecarboxamide, N-(2-pyridin-2-ylethyl) p-menthanecarboxamide and menthyl lactate, the composition being characterized in that, in a triangular ternary phase diagram of (N-(4-cyanomethyl-phenyl) p-menthanecarboxamide, N-(2-pyridin-2-ylethyl) p-menthanecarboxamide and menthyl lactate, the composition falls within that portion of the diagram bounded by the coordinates of the following table (l). The compositions are stable liquids, able to be stored and easily incorporated into products, and giving superior cooling properties with respect to the same quantities of compounds added as powders.

公开(公告)号：WO2022028976A1

公开(公告)日：2022-02-10

申请号：PCT/EP2021/071109

申请日：2021-07-28

Applicant: GIVAUDAN SA

Inventor： BARTHOLOMEW, Tracy ,  SAJI, Norikazu ,  COCITO ARMANINO, Nicolas

IPC: A61K8/49 ,  A61K8/42 ,  A61K8/365 ,  A61Q11/00 ,  A61K2800/244 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4986

Abstract: Compositions comprising at least one cooling compound and a solvent, and the use of said composition in a flavour or fragrance composition.

公开(公告)号：WO2012113873A2

公开(公告)日：2012-08-30

申请号：PCT/EP2012/053082

申请日：2012-02-23

Applicant: GIVAUDAN SA ,  TALSMA, Paul Alexander ,  BARTHOLOMEW, Tracy

Inventor： TALSMA, Paul Alexander ,  BARTHOLOMEW, Tracy

IPC: A61K8/34

CPC classification number: A61K8/34 ,  A23L27/203 ,  A23L27/205 ,  A23L27/2054 ,  A23V2002/00 ,  A61K8/42 ,  A61K8/4926 ,  A61K2800/244 ,  A61K2800/805 ,  A61K2800/92 ,  A61Q11/00

Abstract: The invention relates to flavour compositions comprising a mixture of coolant compounds comprising menthol and a menthane carboxamide selected from N-(4-cyanomethylphenyl) p-menthanecarboxamide. 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide, or a mixture of N- (4-cyanomethylphenyl) p-menthanecarboxamide and 2- isopropyl-5-methyi-N-(2-(pyridin-4-yOethylJcyclohexanecarboxamide, wherein the total amount of menthane carboxamide is about 0.1 to 10%.

Abstract translation: 本发明涉及包含薄荷醇和选自N-（4-氰基甲基苯基）对薄荷烷酰胺的薄荷烷甲酰胺的冷却剂化合物的混合物的风味组合物。 2-（异丙基-5-甲基-N-（2-（吡啶-4-基）乙基）环己烷甲酰胺或N-（4-氰基甲基苯基）对薄荷烷甲酰胺和2-异丙基-5-甲基-N-（ 2-（吡啶-4-基乙基）环己烷甲酰胺，其中薄荷烷甲酰胺的总量为约0.1至10％。