A FLUORESCENCE SENSOR FOR DETECTING BIOMARKERS IN A SWEAT SAMPLE

    公开(公告)号:WO2022263902A1

    公开(公告)日:2022-12-22

    申请号:PCT/IB2021/055426

    申请日:2021-06-21

    Abstract: A system may be introduced for detecting biomarkers in a sweat sample. The system may include a skin patch and a fluorescence detector. The skin patch may include an adhesive tape with a central hole. The skin patch may further include a fluorescence sensor removably attached on the adhesive tape. The skin patch may further include at least one cotton thread. The fluorescence detector may include a light-tight chamber. The fluorescence detector may further include a sample holder removably disposed within the light-tight chamber. The fluorescence detector may further include at least one UV-LED light source may be positioned above the sample holder. The fluorescence detector may further include at least a light filter may be disposed within the light-tight chamber above the UV-LED light source. The fluorescence detector may further include an image capturing device may be disposed within the light-tight chamber.

    MEASUREMENT OF BILIRUBIN CONCENTRATION IN BLOOD SAMPLES

    公开(公告)号:WO2020100128A1

    公开(公告)日:2020-05-22

    申请号:PCT/IB2019/060100

    申请日:2019-11-24

    Abstract: A method for measuring bilirubin concentration in a sample may include preparing a sensing element, where the sensing element may include a plurality of carbon dots, adding the sample to the sensing element, where the sample may include a plurality of bilirubin molecules, obtaining a first grayscale image of the sensing element under ultra-violate (UV) irradiation, irradiating visible light with a wavelength between 470 nm and 490 nm on the sensing element, obtaining a second grayscale image of the sensing element under ultra-violate (UV) irradiation, calculating a light intensity difference by calculating a difference between a first average light intensity of the first grayscale image and a second average light intensity of the second image, and determining the bilirubin concentration based on a correlation between the bilirubin concentration and the light intensity difference.

Patent Agency Ranking