公开(公告)号：WO2015034840A8

公开(公告)日：2015-05-28

申请号：PCT/US2014053743

申请日：2014-09-02

Applicant: GROSS JUSTUS ,  SPECTRANETICS CORP

Inventor： GROSS JUSTUS

IPC: A61B18/24 ,  A61M31/00

CPC classification number: A61B18/245 ,  A61B18/14 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/0041 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2018/1861 ,  A61B2018/2211 ,  A61B2218/001 ,  A61M25/0026 ,  A61M2025/0031 ,  A61M2025/004 ,  A61N7/00

Abstract: The present disclosure relates to methods and systems for removing a vascular obstruction in a subject using a combination ofthrombolytic and laser ablation therapy. Treatment methods include positioning a catheter adjacent to an obstruction within a vessel of a subject. A portion of the obstruction may be ablated by delivering laser energy through the optical fibers to the distal end of the catheter, where the optical fibers are exposed, and circulating a fluid containing one or more thrombolytic agents to a remaining portion of the obstruction for a predetermined amount time. Fluid containing one or more thrombolytic agents capable of dissolving a remaining portion of the obstruction may be circulated through the fluid delivery lumen and removed through the fluid removal lumen.

Abstract translation: 本公开涉及使用溶栓和激光消融治疗的组合来去除受试者中的血管阻塞的方法和系统。 治疗方法包括将导管邻近受试者血管内的梗阻定位。 障碍物的一部分可以通过将激光能量通过光纤传递到导管的远端而消融，其中光纤被暴露，并且将含有一种或多种溶栓剂的流体循环到阻塞物的剩余部分 预定时间。 含有一种或多种能够溶解阻塞物的剩余部分的溶栓剂的流体可循环通过流体输送腔并通过流体移除管腔移除。