公开(公告)号：WO2019173503A3

公开(公告)日：2019-09-12

申请号：PCT/US2019/020999

申请日：2019-03-06

Applicant: IMCARE BIOTECH, LLC

Inventor： LU, Xuanyong ,  LU, Felix

IPC: C07K16/30 ,  C07K16/38 ,  G01N33/53 ,  A61P35/00

Abstract: Anti-AS-SPIK antibodies are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to diagnose disorders characterized by the expression of AS-SPIK (e.g., liver cancer). Diagnostic methods and kits comprising the anti-AS-SPIK antibodies are also disclosed.

公开(公告)号：WO2021050217A1

公开(公告)日：2021-03-18

申请号：PCT/US2020/046782

申请日：2020-08-18

Applicant: IMCARE BIOTECH, LLC.

Inventor： LU, Xuanyong ,  LU, Felix

IPC: A61P35/00 ,  C07K16/40

Abstract: Two classes of anti-AS-SPIK antibodies that specifically bind to one of two different conformational epitopes are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to diagnose and/or treat disorders characterized by the expression of AS-SPIK (e.g., liver cancer). Diagnostic methods and kits comprising the anti-AS-SPIK antibodies are also disclosed.

公开(公告)号：WO2021007338A1

公开(公告)日：2021-01-14

申请号：PCT/US2020/041228

申请日：2020-07-08

Applicant: IMCARE BIOTECH, LLC.

Inventor： LU, Xuanyong ,  LU, Felix

IPC: A61P35/00 ,  C07K16/38

Abstract: Anti-AS-SPIK antibodies are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to diagnose and/or treat disorders characterized by the expression of AS-SPIK (e.g., liver cancer). Diagnostic methods and kits comprising the anti-AS-SPIK antibodies are also disclosed.