METHODS FOR CONTROLLING FLEA AND TICK INFESTATIONS IN A MAMMAL

    公开(公告)号:WO2022192648A1

    公开(公告)日:2022-09-15

    申请号:PCT/US2022/019913

    申请日:2022-03-11

    摘要: An active material is orally administered to a mammal substantially daily, which eventually increases the mammal's blood concentration of the active material to an amount effective to control a flea and/or tick infestation of the mammal. The oral administration is then discontinued for a time period of at least one day, yet the mammal's blood concentration of active material remains sufficiently high to control the flea and/or tick infestation. The time period can be over three days or over seven days. After the period of time has elapsed, administration of substantially daily doses can be resumed to continue maintaining the mammal's blood concentration of active material in an amount effective to control the flea and/or tick infestation. The discontinuing of the oral administration can occur several times over the course of a month or longer. Also disclosed is a method for establishing a regimen for administering an active material for controlling flea and/or tick infestations in a mammal using a dosage that is reduced from the label dose for a corresponding time period.