公开(公告)号：WO1994020188A1

公开(公告)日：1994-09-15

申请号：PCT/US1994000179

申请日：1994-03-02

Applicant: ISCO, INC.

Inventor： ISCO, INC. ,  JAMESON, Daniel, Gene

IPC: B01D11/00

CPC classification number: F04B9/042 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

Abstract: To collect analyte in a supercritical fluid extraction process, the extractant flows to a collection container (130) under pressure. In one embodiment, the collection container (130) contains collection solvent (144) through which the extractant flows to partition analyte. The extractant adds to the liquid and when the collection solvent-extractant mixture rises to a heating zone, the extractant vaporizes selectively since its vapor pressure is higher than the vapor pressure of the collection solvent (144). When its pressure exceeds a preset valve (148) pressure it is vented so that extractant continually leaves the collection container (130). After the extraction is complete, the analyte is concentrated in the collection solvent (144). In another embodiment, the collection vessel includes a solid material on which the analyte collects. It is removed under pressure by a solvent that is concentrated under pressure.

Abstract translation: 为了在超临界流体萃取过程中收集分析物，萃取剂在压力下流到收集容器（130）。 在一个实施方案中，收集容器（130）包含收集溶剂（144），萃取剂通过该收集溶剂流动以分配分析物。 萃取剂添加到液体中，并且当收集溶剂萃取剂混合物升至加热区时，萃取剂由于其蒸汽压高于收集溶剂（144）的蒸汽压力而选择性地蒸发。 当其压力超过预设阀（148）压力时，其被排出，使得萃取剂连续地离开收集容器（130）。 萃取完成后，将分析物浓缩在收集溶剂（144）中。 在另一个实施方案中，收集容器包括分析物在其上收集的固体材料。 在压力下通过在压力下浓缩的溶剂除去。

公开(公告)号：WO1994020189A1

公开(公告)日：1994-09-15

申请号：PCT/US1994002260

申请日：1994-03-02

Applicant: ISCO, INC.

Inventor： ISCO, INC. ,  JAMESON, Daniel, Gene ,  MACOMBER, Robert, Joseph ,  ALLINGTON, Robert, William

IPC: B01D11/00

CPC classification number: G21F5/015 ,  B01D11/0203 ,  B01D11/0407 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  B01D15/40

Abstract: To avoid deposits on the restrictor that channels extractant into a collector (1901), a heated capillary tube (1900) pressure release restrictor has a thermally insulated outlet end in a collecting trap (1908) substantially colder than the capillary tube (1900). The restrictor is heated between the insulation (1906) and the capillary tube (1908) by Joulean heating. The solvent in the trap (1908) is at a pressure of 5 to 200 psi above atmospheric pressure. The thermal resistance of the insulation (1906) is selected to reduce the heat added to the extractant to a minimum, to keep the extractant from freezing, and to reduce partitioning of the extract and extractant. It has a thermal conductivity no greater than 60 BTU's per hour, per square foot, per inch for a one degree Fahrenheit difference.

Abstract translation: 为了避免限流器上的沉积物将萃取物引入收集器（1901）中，加热的毛细管（1900）压力释放限制器在基本上比毛细管（1900）更冷的收集阱（1908）中具有绝热出口端。 限流器通过Joulean加热在绝缘体（1906）和毛细管（1908）之间加热。 捕集器（1908）中的溶剂的压力高于大气压力5至200 psi。 选择绝缘（1906）的热阻以将添加到萃取剂中的热量降至最低，以防止萃取剂冻结，并减少萃取物和萃取剂的分配。 对于一华氏度的差值，其导热率不大于每小时60BTU，每平方英尺。

公开(公告)号：WO1995002176A1

公开(公告)日：1995-01-19

申请号：PCT/US1994007482

申请日：1994-07-05

Applicant: ISCO, INC.

Inventor： ISCO, INC. ,  KEEFER, Richard, Eugene

IPC: G01N01/00

CPC classification number: G01N1/10 ,  B01L9/06 ,  G01N1/18 ,  G01N33/18 ,  G01N2001/1043 ,  G01N2001/1075 ,  G01N2001/1081

Abstract: To draw samples of fluid at remote locations, one of a plurality of sampler configurations is selected from configurations that have a universal base, a selected one of a composite container holder or locator, 12-container rain water runoff container holder and sequential sample multiple container holder; clampdown, control section, and cover. The selected configuration is brought to the remote site (12). Samples are drawn at the site (14) in a predetermined time sequence. After a sequence is completed, a new selected container is put into an insulated shipping carton with ice and containers and brought to the site (16). At the site, the old container holder is removed and the ice is poured into the shipping carton (18). The new container carrier is inserted into the sampler with ice (20). The old container carrier with sample in the containers is put into the shipping carton with the remaining ice and brought to the laboratory (22).

Abstract translation: 为了在远程位置抽取液体样品，从具有通用基座，复合容器保持器或定位器中的选定一个，12容器雨水径流容器保持器和顺序样品多容器的配置中选择多个采样器配置中的一个 持有人; 夹紧，控制部分和盖子。 所选择的配置被带到远程站点（12）。 样品以预定的时间顺序在位点（14）处绘制。 序列完成后，将新选择的容器放入带有冰和容器的绝缘运输纸箱中并带到现场（16）。 在现场，旧的集装箱架被移走，并将冰倒入运送纸箱（18）中。 新的集装箱运输车用冰（20）插入取样器。 将集装箱中的样品的旧集装箱运输箱放入运送纸箱中，剩余的冰块送到实验室（22）。

公开(公告)号：WO1994020190A1

公开(公告)日：1994-09-15

申请号：PCT/US1994002261

申请日：1994-03-02

Applicant: ISCO, INC.

Inventor： ISCO, INC. ,  CLAY, Dale, Lee ,  ALLINGTON, Robert, William ,  LIESCHESKI, Phillip, Bearnard, III ,  WINTER, Robin, Randall ,  JAMESON, Daniel, Gene

IPC: B01D11/00

CPC classification number: F04B9/042 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

Abstract: To supply supercritical fluid to an automatic supercritical fluid extractor and collect extract from the extractor, sample holding cartridges (30A) are lifted one by one in series by an elevator plug into a pressure chamber (24A). An inlet at the top of the cartridge (30A) engages a pressure vessel inlet for the extractant so that extractant flows into the cartridge (30A) and into the space between the cartridge and inner walls of the pressure chamber (24A). The outlets from the cartridge (30A) and pressure vessel communicate with the collector (408) and exhaust through passageways in the plug. The plug has cleaning ports for cleaning seals and the outlet from the cartridge (30A) flows past the seals. The collector (408) lifts vials into place and can precool the collection solvent, and later as part of the collection procedure, heat and pressurize the collector (408).

Abstract translation: 为了将超临界流体提供给自动超临界流体提取器并从提取器收集提取物，样品保持盒（30A）通过电梯塞一个接一个地提升到压力室（24A）中。 药筒（30A）顶部的入口接合用于萃取剂的压力容器入口，使得萃取剂流入料盒（30A）并进入料筒与压力室（24A）的内壁之间的空间。 来自盒（30A）和压力容器的出口与收集器（408）连通，并通过插头中的通道排出。 插头具有用于清洁密封件的清洁端口，并且来自盒（30A）的出口流过密封件。 收集器（408）将小瓶提升到适当位置并且可以预先冷却收集溶剂，并且随后作为收集过程的一部分，对收集器（408）进行加热和加压。

公开(公告)号：WO1995003106A1

公开(公告)日：1995-02-02

申请号：PCT/US1994008341

申请日：1994-07-20

Applicant: ISCO, INC.

Inventor： ISCO, INC. ,  ALLINGTON, Robert, William ,  WALTERS, Henry, Leroy ,  JAMESON, Daniel, Gene ,  TEHRANI, Yoossef

IPC: B01D15/08

CPC classification number: B01D11/0203 ,  B01D11/0407 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N2030/6008 ,  G01N2030/6013 ,  B01D15/40

Abstract: A variable-orifice fluid restrictor (11) for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means (1240) adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means (1240) is adjacent to the outer surface of the probe and the orifice means (1240) is adjustable with the adjusting stem. The end of the stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice (1240) for varying the restriction of the fluid passing through the adjustable orifice (1240).

Abstract translation: 与超临界萃取器或色谱仪一起使用的可变孔口流体限制器（11）包括用于高于其临界压力的压力的流体的入口管线，具有内表面和外表面以及近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探头的远端包括适于计量流体并具有第一和第二孔口构件的调节孔装置（1240）和具有第一和第二端的调节杆。 可调节孔装置（1240）与探针的外表面相邻，孔口装置（1240）可用调节杆调节。 杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔（1240），用于改变通过可调节孔的流体的限制 （1240）。