METHODS FOR SYNTHESIS OF DYE-LABELED POLYMERS

    公开(公告)号:WO2023042157A1

    公开(公告)日:2023-03-23

    申请号:PCT/IB2022/058786

    申请日:2022-09-16

    Abstract: Dye-labeled polymers formed from a polymer and a dye are disclosed. Methods for labeling a polymer with a dye are also disclosed. The polymer can have any weight average molecular weight (Mw), particularly a Mw of > 5 megadalton (MDa) or > 6 MDa. The polymer contains reactive group(s) that can be activated by an activation agent in a buffer solution. Upon activation, the polymer bundles and forms activated polymer in a solid form. The activated polymer can react with a reactive group of the dye to form the dye-labeled polymer. By soaking the dye-labeled polymer in a solid form in an aqueous solvent, the dye-labeled polymer can regain the viscosifying property that is the same or substantially the same as the polymer prior to labeling with the dye.

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