公开(公告)号：WO2022104066A1

公开(公告)日：2022-05-19

申请号：PCT/US2021/059151

申请日：2021-11-12

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： DUDUKOVIC, Nikola ,  BAKER, Sarah ,  CAHILL, James, Timothy ,  DAVIS, Jonathan, Tesner ,  DEOTTE, Joshua, R. ,  DUBBIN, Karen, Ruth ,  DUOSS, Eric ,  FONG, Erika, Jo ,  GEMEDA, Hawi, Bacha ,  QIAN, Fang

IPC: B01L3/00

Abstract: The present disclosure relates to an engineered, additively manufactured, microfluidic cellular structure formed from a plurality of cells, wherein the cells are each formed from a plurality of interconnected elements. The cells have voids and each cell is open at upper ends thereof. The cells each communicate at a point below its upper end with a common channel. The cells are each configured to accept a fluid and operate to channel the fluid into the common channel and to hold the fluid received therein for later selective withdrawal from the structure.

公开(公告)号：WO2022051403A1

公开(公告)日：2022-03-10

申请号：PCT/US2021/048723

申请日：2021-09-01

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： FEASTER, Jeremy, Taylor ,  BAKER, Sarah ,  CORRAL, Daniel ,  DUOSS, Eric

IPC: C25B3/00 ,  C25B3/26 ,  C25B3/01 ,  C25B3/07 ,  C25B1/23 ,  C25B1/04 ,  C25B15/08 ,  C25B9/17 ,  B33Y80/00

Abstract: System and method relates to an advanced manufactured vapor-fed electrochemical reactor (AM-VFR) system comprising a cathode gas compartment comprising a first inlet, and a first outlet, a catholyte compartment having a centrally located window for a cathode and an optional membrane, a second inlet, a second outlet, and a reference electrode, an anolyte compartment having a centrally located window for the membrane and an anode, a third inlet and a third outlet and an anode gas compartment having a fourth inlet and a fourth outlet, wherein the cathode, wherein the cathode is disposed between the cathode gas compartment and the catholyte compartment, wherein the membrane is disposed between the catholyte compartment and the anolyte compartment, wherein the anode is disposed between the anolyte compartment and the anode gas compartment, and wherein one or more of the cathode gas compartment, the catholyte compartment, the anolyte compartment and the anode gas compartment are made of a 3D printing plastic. Methods for making and using the system are also disclosed.

公开(公告)号：WO2021076853A1

公开(公告)日：2021-04-22

申请号：PCT/US2020/055923

申请日：2020-10-16

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： DUDUKOVIC, Nikola ,  AINES, Roger ,  BAKER, Sarah ,  DEOTTE, Joshua R. ,  DUOSS, Eric B. ,  FEASTER, Jeremy Taylor ,  GOLOBIC, Alexandra ,  MANCINI, Julie ,  SPADACCINI, Christopher M. ,  WATTS, Seth Evan ,  TROKSA, Michael John

IPC: B29C64/153 ,  B29C64/255 ,  B29C64/209 ,  B29C64/268 ,  B29C64/393 ,  B29C64/227 ,  B29C64/321 ,  B33Y30/00 ,  B33Y50/02 ,  B33Y40/00

Abstract: The present disclosure relates to an additive manufacturing system. In one embodiment the system makes use of a reservoir for holding a granular material feedstock. A nozzle is in communication with the reservoir for releasing the granular material feedstock in a controlled fashion from the reservoir to form at least one layer of a part. An excitation source is included for applying a signal which induces a controlled release of the granular material feedstock from the nozzle as needed, to pattern the granular material feedstock as necessary to form a layer of the part.

公开(公告)号：WO2017127752A1

公开(公告)日：2017-07-27

申请号：PCT/US2017/014444

申请日：2017-01-20

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： STOLAROFF, Joshuah K. ,  AINES, Roger ,  BAKER, Sarah ,  BLANCHETTE, Craig D. ,  MAITI, Amitesh ,  VERICELLA, John ,  OAKDALE, James S. ,  YE, Congwang

IPC: B01D53/04 ,  B01D53/14 ,  B01D53/62 ,  B01D53/84 ,  B01D53/86 ,  C12M1/40

CPC classification number: B01J37/0072 ,  B01J31/003 ,  B01J31/06 ,  C12N11/04 ,  C12N11/08 ,  C12P7/04

Abstract: A membrane includes a polymeric network configured to separate a first fluid and a second fluid. A plurality of enzymatic reactive components are embedded within the polymeric network. According to another embodiment, a bioreactor includes a lattice of three dimensional structures, each including a membrane having: a polymeric network configured to separate a first fluid and a second fluid; and a plurality of enzymatic reactive components embedded within the polymeric network. A microcapsule for selective catalysis of gas(es) includes: a polymeric shell permeable to target gas(es); and biocatalyst(s) disposed in the shell. Methods of forming such microcapsules include: emulsifying biocatalyst(s) in a polymer precursor mixture; emulsifying the mixture in an aqueous carrier solution; crosslinking the polymer precursor mixture to form a plurality of microcapsules. Methods of using the microcapsules include: exposing a plurality of the biocatalytic microcapsules to target gas(es).

Abstract translation: 膜包括构造成分离第一流体和第二流体的聚合物网络。 多种酶活性组分嵌入聚合物网络内。 根据另一个实施方案，生物反应器包括三维结构的网格，每个三维结构包括膜，所述膜具有：聚合物网络，其被配置为分离第一流体和第二流体; 和嵌入聚合物网络内的多种酶反应组分。 用于选择性催化气体的微胶囊包括：可透过目标气体的聚合物壳; 和布置在外壳中的生物催化剂。 形成这种微胶囊的方法包括：在聚合物前体混合物中乳化生物催化剂; 将该混合物在含水载体溶液中乳化; 使聚合物前体混合物交联以形成多个微胶囊。 使用微胶囊的方法包括：将多个生物催化微胶囊暴露于目标气体（一种或多种）。

公开(公告)号：WO2022192667A1

公开(公告)日：2022-09-15

申请号：PCT/US2022/019944

申请日：2022-03-11

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： BECK, Victor Alfred ,  BAKER, Sarah ,  CHANDRASEKARAN, Swetha ,  DUOSS, Eric ,  FORIEN, Jean-Baptiste ,  IVANOVSKAYA, Anna Nikolaevna ,  WORSLEY, Marcus

IPC: H01M4/96 ,  H01M4/86 ,  H01M4/88 ,  H01M8/18 ,  B33Y10/00 ,  B33Y80/00 ,  D01F9/12

Abstract: Disclosed are flow-through electrode devices and techniques for making flow-through electrodes. In one aspect, a flow through electrode apparatus comprises one or more fiber layers. Each fiber layer comprises a plurality of fibers oriented to be orthogonal to a flow direction of a fluid. The plurality of fibers are configured to cause an inertial flow of the fluid around the plurality of fibers at a first flow rate of the fluid.

公开(公告)号：WO2018237336A1

公开(公告)日：2018-12-27

申请号：PCT/US2018/039113

申请日：2018-06-22

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： CAMPBELL, Patrick ,  BAKER, Sarah ,  HERNANDEZ, Maira ,  KNIPE, Jennifer Marie ,  STOLAROFF, Joshuah K.

IPC: B01J20/08 ,  B01J20/16 ,  B01J20/28

Abstract: In accordance with one aspect of the presently disclosed inventive concepts, a product includes a ceramic material having an open cell structure with a plurality of pores and an aqueous sorbent solution in the pores of the ceramic material. The pores connect through the ceramic material from one side of the ceramic material to an opposite side of the ceramic material. A portion of the aqueous sorbent solution is retained in the pores of the ceramic material by capillary action.

公开(公告)号：WO2020096601A1

公开(公告)日：2020-05-14

申请号：PCT/US2018/059808

申请日：2018-11-08

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： DUDUKOVIC, Nikola ,  AINES, Roger ,  BAKER, Sarah ,  DEOTTE, Joshua R. ,  DUOSS, Eric ,  FEASTER, Jeremy Taylor ,  GOLOBIC, Alexandra ,  MANCINI, Julie ,  SPADACCINI, Christopher M. ,  WATTS, Seth Evan

IPC: B29C64/141 ,  B22F3/105 ,  B29C64/393 ,  B29C64/209 ,  B29C64/268 ,  B33Y50/02 ,  B33Y30/00

Abstract: The present disclosure relates to an additive manufacturing system. In one embodiment the system makes use of a reservoir for holding a granular material feedstock. A nozzle is in communication with the reservoir for releasing the granular material feedstock in a controlled fashion from the reservoir to form at least one layer of a part. An excitation source is included for applying a signal which induces a controlled release of the granular material feedstock from the nozzle as needed, to pattern the granular material feedstock as necessary to form a layer of the part.

公开(公告)号：WO2019089596A1

公开(公告)日：2019-05-09

申请号：PCT/US2018/058214

申请日：2018-10-30

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： KNIPE, Jennifer Marie ,  BAKER, Sarah ,  DEOTTE, Joshua R. ,  QIAN, Fang

IPC: A61K39/00 ,  A61K39/02 ,  A61K39/116

CPC classification number: C12M25/16 ,  C12M21/00 ,  C12M23/24 ,  C12M25/14

Abstract: In one inventive concept, a mixture for forming polymer-encapsulated whole cells includes a pre-polymer, a photoinitiator, and a plurality of whole cells. In another inventive concept, a product includes a structure including a plurality of whole cells encapsulated in a polymer, where the polymer is cross-linked.

公开(公告)号：WO2021061767A1

公开(公告)日：2021-04-01

申请号：PCT/US2020/052210

申请日：2020-09-23

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： DEOTTE, Joshua R. ,  BAKER, Sarah ,  DUOSS, Eric ,  KNIPE, Jennifer Marie ,  QIAN, Fang ,  RUELAS, Samantha

IPC: B01L3/00

Abstract: An engineered unit cell is disclosed for flowing a fluid therethrough in three dimensions. The unit cell may have a substrate with a plurality of flow channels around and between struts formed within the substrate. The struts may each be formed with a desired shape and orientation within the substrate to achieve a desired degree of fluid flow through the flow channels, in each of one of three dimensions, through the unit cell.

公开(公告)号：WO2021041220A1

公开(公告)日：2021-03-04

申请号：PCT/US2020/047424

申请日：2020-08-21

Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

Inventor： DUDUKOVIC, Nikola ,  BAKER, Sarah ,  BECK, Victor Alfred ,  CHANDRASEKARAN, Swetha ,  DEOTTE, Joshua R. ,  DUOSS, Eric B. ,  FEASTER, Jeremy Taylor ,  KNIPE, Jennifer Marie ,  MANCINI, Julie ,  OAKDALE, James ,  QIAN, Fang ,  WORSLEY, Marcus A.

IPC: B01J19/00 ,  B01L3/00

Abstract: The present disclosure relates to an engineered cellular fluidics structure. The structure may have a plurality of tessellated cells formed from a plurality of interconnected elements, with the interconnected struts formed from a curable resin. The interconnected elements form voids within each cell, with the voids communicating with one another. The elements may be formed such that the voids have a non-uniform dimension to create a varying porosity within the structure.