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公开(公告)号：WO2018149620A1
公开(公告)日：2018-08-23
申请号：PCT/EP2018/051942
申请日：2018-01-26
Applicant: NORTON (WATERFORD) LIMITED
Inventor： BUCK, Daniel , PRENDERGAST, Paul , WALSH, Declan
Abstract: An inhaler (10) for the inhalation of inhalable substances comprise: a canister (50) having an interior reservoir (84) containing pressurised inhalable substances including fluid; a metering valve (52) including a metering chamber (82) and a valve stem (54) defining a communication path between the metering chamber and the interior reservoir, the communication path (86) including an opening (106) configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas such as air located within the metering chamber is replaced with liquid from the interior reservoir.
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公开(公告)号：WO2018141737A1
公开(公告)日：2018-08-09
申请号：PCT/EP2018/052250
申请日：2018-01-30
Applicant: NORTON (WATERFORD) LIMITED
Inventor： BUCK, Daniel , WALSH, Declan , PRENDERGAST, Paul
IPC: G01N33/44
Abstract: Disclosed herein is a quality control method for predicting premature degradation in mechanical properties of a series of moulded plastics components, the moulded plastics components being formed from a batch mixture comprising a cross-linkable polymer and a peroxide cross-linking agent. The method comprises selecting a subset of the series of moulded plastics components and obtaining a material specimen from the subset; and then extracting and measuring a residual peroxide content of the specimen. According to the invention,the measured residual peroxide content is representative of a probability of the premature age-related degradation in the entire series of moulded plastics components, and may therefore be compared against a threshold residual peroxide content to determine whether the entire series of components is of acceptable quality.
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公开(公告)号：WO2018149617A1
公开(公告)日：2018-08-23
申请号：PCT/EP2018/051927
申请日：2018-01-26
Applicant: NORTON (WATERFORD) LIMITED
Inventor： BUCK, Daniel , PRENDERGAST, Paul , WALSH, Declan
Abstract: An inhaler (10) has a main body for accommodating a medicament reservoir (84), a canister fire system for moving a canister (50) to release a dose in response to air flow, a cap housing (12) for enclosing the canister fire system and canister within an interior chamber defined by the main body (14) and a cap housing, wherein a lock system (250) is provided for locking the cap housing on the main body.
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公开(公告)号：WO2016030521A1
公开(公告)日：2016-03-03
申请号：PCT/EP2015/069781
申请日：2015-08-28
Inventor： OLIVERAS, Enrique Calderon , BUCK, Daniel , FLEMING, Frederic Scott
IPC: A61M15/00
CPC classification number: A61M15/0065 , A61M15/00 , A61M15/0026 , A61M15/0071 , A61M15/008 , A61M15/009 , A61M15/0091 , A61M2205/3331 , A61M2205/3576 , A61M2205/3584 , A61M2205/50 , A61M2205/58 , A61M2205/583 , A61M2205/584 , A61M2205/587 , A61M2209/088
Abstract: An inhaler includes a mouthpiece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalat ion.
Abstract translation: 吸入器包括接口盖，压力传感器，第一指示器和第二指示器。 第一指示器可以被配置为基于盖的状态来指示，并且第二指示器可以被配置为基于压力传感器的输出来指示。 例如，当接口盖打开时，第一指示器可以点亮，并且一定剂量的药物可以从储存器转移到定量杯。 如果吸入药物的量达到用于成功吸入的预定阈值，则第二指示剂可能会点亮。
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公开(公告)号：WO2021255036A1
公开(公告)日：2021-12-23
申请号：PCT/EP2021/066130
申请日：2021-06-15
Applicant: NORTON (WATERFORD) LIMITED
Inventor： CROWLEY, Peter John , HAZENBERG, Jan Geert , BUCK, Daniel , EDLIN, Dr Christopher David , SHAH, Hardik Kirtikumar
IPC: A61M15/00 , A61M15/0003 , A61M15/0025 , A61M15/0028 , A61M15/0043
Abstract: Provided is a blister pack for a dry powder inhaler, which dry powder inhaler is configured to deliver a first powder medicament and a second powder medicament different from the first powder medicament. The first and second powder medicaments are contained within blister pockets (12A, 12B) defined in a strip (10). A series (11) of blister pockets is defined in the strip, which series extends linearly along the length of the strip. The first and second powder medicaments are contained in blister pockets, e.g. respective blister pockets, of the series. Alternatively or additionally, each of the blister pockets is elongated such as to have a largest dimension (20) parallel with the length of the strip. These measures, either individually or in combination, enable minimizing of the width of the strip in spite of the strip accommodating both the first and second powder medicaments. This, in turn, may enable the depth/thickness of the dry powder inhaler to be minimized, and/or additional space to be provided inside the dry powder inhaler for accommodating, for example, use detection and wireless connectivity electronics for sending use detection data to an external device, such as a smartphone.
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Patent Agency Ranking
公开(公告)号：WO2016050957A1
公开(公告)日：2016-04-07
申请号：PCT/EP2015/072795
申请日：2015-10-02
Applicant: NORTON (WATERFORD) LIMITED
Inventor： BUCK, Daniel
IPC: A61M15/00
CPC classification number: A61M15/009 , A61M15/0001 , A61M2207/00
Abstract: A fluid dispensing apparatus (2), comprising a body (4), said body having an orifice (8) configured to allow the fluid to be dispensed from the apparatus, wherein the orifice has been formed by machining and a method of manufacturing thereof.
Abstract translation: 一种流体分配装置（2），包括主体（4），所述主体具有孔口（8），所述孔口构造成允许流体从所述装置分配，其中所述孔口通过机械加工形成，以及其制造方法。
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公开(公告)号：WO2016033421A1
公开(公告)日：2016-03-03
申请号：PCT/US2015/047369
申请日：2015-08-28
Applicant: MICRODOSE THERAPEUTX, INC. , NORTON (WATERFORD) LIMITED
Inventor： MORRISON, Mark, Steven , WEITZEL, Douglas, E. , OLIVERAS, Enrique, Calderon , BUCK, Daniel
CPC classification number: A61B5/087 , A61B5/097 , A61B5/4833 , A61B2562/028 , A61B2562/0285 , A61M15/00 , A61M15/009 , A61M15/0096 , A61M16/0051 , A61M16/0063 , A61M16/021 , A61M2016/0027 , A61M2209/088
Abstract: A compliance monitoring module for an inhaler comprising : a miniature pressure sensor, a sensor port of said sensor being configured to be pneumatically coupled to a flow channel of said inhaler through which a user can inhale; a processor configured to : receive data from a sensing element of the pressure sensor; receive data from a mode sensor configured to detect when the inhaler changes from an inactive mode to an active mode; and based on said data from said pressure sensor sensing element and said data from said mode sensor, compile a compliance report; and a transmitter configured to issue said compliance report.
Abstract translation: 一种用于吸入器的合规性监测模块，包括：微型压力传感器，所述传感器的传感器端口被配置为气动联接到用户可以吸入的所述吸入器的流动通道; 处理器，其被配置为：从所述压力传感器的感测元件接收数据; 从配置成检测何时吸入器从非活动模式变为活动模式的模式传感器接收数据; 并且基于来自所述压力传感器感测元件的所述数据和来自所述模式传感器的所述数据，编制合规报告; 以及被配置为发布所述合规性报告的发射机。
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公开(公告)号：WO2020234201A1
公开(公告)日：2020-11-26
申请号：PCT/EP2020/063741
申请日：2020-05-15
Applicant: NORTON (WATERFORD) LIMITED
Inventor： CALDERON OLIVERAS, Enrique , BUCK, Daniel
Abstract: A system may include an external device and an inhaler. The external device may include a processor, a communication circuit, and memory. The inhaler may include a mouthpiece, medicament, a mechanical dose counter, and an electronics module comprising a processor and a communication circuit. The electronics module may record a dosing event when the inhaler is actuated, such as when the mouthpiece cover is opened, and send a signal indicating the dosing event to the external device. The external device may receive a mechanical dose reading of the mechanical dose counter, determine an electronic dose reading based on the signal indicating the dosing event, determine that a discrepancy between the mechanical dose reading and the electronic dose reading exceeds a threshold, and notify the user of the discrepancy, for example, by providing a notification to the user by way of a mobile application residing on the external device.
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公开(公告)号：WO2018149619A1
公开(公告)日：2018-08-23
申请号：PCT/EP2018/051937
申请日：2018-01-26
Applicant: NORTON (WATERFORD) LIMITED
Inventor： BUCK, Daniel , PRENDERGAST, Paul , WALSH, Declan
IPC: A61M15/00
Abstract: An inhaler housing (14) for an inhaler (10) for inhaling inhalable substances, the inhaler having: a body (14) and a dose counter (24) with a return spring (28), wherein a distinct guide surface (162) is provided for guiding the end of the return spring into a recess (152), the distinct guide surface being wider than an entrance mouth (160) of the recess, a dose counter chamber (22) being provided which is separated from a tubular interior space (182) of the inhaler by a barrier (180), the barrier including a stepped upper wall area (184) including at least three steps (186, 188, 190, 192) at different levels, the inhaler having a valve stem block (62) having an inner bore and a valve stem block having a seal (224) in the inner bore with a second diameter which is smaller than a first diameter of the inner bore, the inhaler having a canister (150) being adapted to move during operation between 1 and 4 mm, a drive being arranged to apply a firing force of between 15N and 60N of force to the canister at a position of the canister relative to a valve stem (54) at which the canister fires.
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公开(公告)号：WO2018091957A1
公开(公告)日：2018-05-24
申请号：PCT/IB2017/001287
申请日：2017-09-14
Applicant: NORTON (WATERFORD) LIMITED
Inventor： CALDERSON OLIVERAS, Enrique , BUCK, Daniel , KANTOR, Erica, Jamie , WEIR, Ross, William , ROCHE, James , GARDNER, Steven, David , KIVLIN, Robert, Owen
Abstract: The introduction of electronics into a drug deliver device may introduce certain technical challenges, such as durability, electro-mechanical integration, and drug delivery performance. The present disclosure provides solutions for inclusion of an electronics module with an inhaler. For example, heat stakes may be used to secure a printed circuit board (PCB) to an electronics module's housing. Also for example, a slider may be used to transfer vertical movement of an inhaler's yoke to an electronics module's switch. Also for example, certain seals may be used when interfacing the electronics module to other portions of the device's housing to achieve a desired performance.
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