公开(公告)号：WO2021040736A1

公开(公告)日：2021-03-04

申请号：PCT/US2019/049099

申请日：2019-08-30

申请人： OBSIDIAN THERAPEUTICS, INC.

发明人： SURI, Vipin ,  BRISKIN, Michael Joseph ,  DOLINSKI, Brian ,  ELPEK, Kutlu, Goksu ,  EZELL, Tucker ,  HELLER, Scott Francis ,  INNISS, Mara, Christine ,  KASSUM, Tariq A. ,  KOSMIDER, Nicole ,  KULKARNI, Abhishek ,  LANGLEY, Meghan ,  LI, Dan Jun ,  OLS, Michelle Lynn ,  PRIMACK, Benjamin J. ,  RICHARDSON, Celeste ,  SHAMAH, Steven Mark ,  STORER, James ,  SUN, Dexue ,  BALAKRISHNAN, Vijaya ,  BRADBURY, Andrew R. M. ,  ERASMUS, Michael Frank ,  FERRARA, Fortunato

IPC分类号： A61K38/17 ,  C07K14/52 ,  C07K14/54 ,  C07K14/715 ,  C07K16/28 ,  C12N9/06 ,  C12N9/90 ,  C12N5/0783 ,  A61K2039/5156 ,  A61K2039/5158 ,  A61K35/17 ,  A61K38/00 ,  A61K39/001112 ,  A61P35/00 ,  C07K14/5434 ,  C07K14/5443 ,  C07K16/2803 ,  C07K2317/70 ,  C07K2319/00 ,  C07K2319/03 ,  C07K2319/33 ,  C12N5/0636 ,  C12N9/003 ,  C12Y105/01003 ,  C12Y502/01008

摘要： The present invention provides biocircuit systems, effector modules and compositions for cancer immunotherapy. Methods for inducing anti-cancer immune responses in a subject are also provided.

公开(公告)号：WO2020185628A1

公开(公告)日：2020-09-17

申请号：PCT/US2020/021582

申请日：2020-03-06

申请人： OBSIDIAN THERAPEUTICS, INC.

发明人： SCHEBESTA, Michael ,  FLEURY, Michelle, Lois ,  ELPEK, Kutlu, Goksu ,  WEISMAN, Elizabeth, Jane ,  SURI, Vipin ,  SUN, Dexue ,  LI, Dan, Jun ,  SHAMAH, Steven, Mark ,  BRISKIN, Michael, Joseph ,  RICHARDSON, Celeste ,  KASSUM, Tariq, A. ,  OLS, Michelle, Lynn ,  DOLINSKI, Brian ,  INNISS, Mara, Christine ,  BRIDEAU, Emily ,  GORI, Jennifer, Leah ,  SETHI, Dhruv, Kam

IPC分类号： C07K14/705 ,  C07K14/47 ,  C07K14/72 ,  C12N9/06

摘要： The present disclosure provides regulatable biocircuit systems, effector modules and compositions for cancer immunotherapy. Methods for inducing anti-cancer immune responses in a subject are also provided.