公开(公告)号：WO2008022225A2

公开(公告)日：2008-02-21

申请号：PCT/US2007076046

申请日：2007-08-15

Applicant: OPTISCAN BIOMEDICAL CORP ,  STERLING BERNHARD B ,  HALL DALE W

Inventor： STERLING BERNHARD B ,  HALL DALE W

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B2560/0223 ,  G01N21/3577

Abstract: Method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement The method reduces the error in the analyte concentration in the presence of interferents The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations From a sample measurement, which may or may not be one of the population, interferents likely to be present are identified, and a calibration coefficient is calculated The calibration coefficient may be applied to the measurement to estimate the analyte concentration In some implementations, the calibration coefficient may be determined as a weighted average of single interferent calibration coefficients In some embodiments, the sample measurement includes a spectroscopic measurement.

Abstract translation: 描述了允许在干扰测量的化合物存在下从测量估计分析物浓度的方法和装置。该方法减少了在存在干扰物的情况下分析物浓度的误差。该方法包括使用一组测量 对于具有一定范围的已知分析物和干扰化合物浓度的大群体获得，从可能或可能不是其中一个群体的样本测量中鉴定可能存在的干扰物，并且计算校准系数校准系数可以是 应用于测量以估计分析物浓度。在一些实施方式中，校准系数可以被确定为单个干扰物校准系数的加权平均值。在一些实施例中，样本测量包括光谱测量。