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1.发明申请SYSTEMS AND METHODS COMPRISING A DROPLET DELIVERY DEVICE AND A BREATHING ASSIST DEVICE FOR THERAPEUTIC TREATMENT 审中-公开包括滴管递送装置和用于治疗处置的呼吸辅助装置的系统和方法
公开(公告)号：WO2017192782A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030929
申请日：2017-05-03
Applicant: PNEUMA RESPIRATORY, INC.
Inventor： GERMINARIO, Louis Thomas , HEBRANK, John H. , HUNTER, Charles Eric , STERN, Thomas P. , HUNTER, Jack C.
Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 µm, so as to target the pulmonary system of the user.
Abstract translation: 公开了用于将精确和可重复的剂量输送到用于肺部使用的受试者的液滴输送装置和相关方法。 液滴输送装置包括壳体，贮存器和排出器机构，以及至少一个差压传感器。 当压差传感器感测到壳体内的预定压力变化时，液滴输送装置自动由使用者呼吸致动。 然后致动液滴输送装置以产生平均喷射液滴直径在可呼吸尺寸范围内（例如小于约5微米）的液滴流，以便瞄准使用者的肺部系统。
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2.发明申请METHODS FOR GENERATING AND DELIVERING DROPLETS TO THE PULMONARY SYSTEM USING A DROPLET DELIVERY DEVICE 审中-公开使用滴液输送装置产生和输送滴落到肺部系统的方法
公开(公告)号：WO2017192771A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030917
申请日：2017-05-03
Applicant: PNEUMA RESPIRATORY, INC.
Inventor： GERMINARIO, Louis Thomas , HEBRANK, John H. , HUNTER, Charles Eric , HUNTER, Jack C. , LI, Chengjie , MAURER, Christopher W.
Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 µm, so as to target the pulmonary system of the user.
Abstract translation: 公开了用于将精确和可重复的剂量输送到用于肺部使用的受试者的液滴输送装置和相关方法。 液滴输送装置包括壳体，贮存器和排出器机构，以及至少一个差压传感器。 当压差传感器感测到壳体内的预定压力变化时，液滴输送装置自动由使用者呼吸致动。 然后致动液滴输送装置以产生平均喷射液滴直径在可呼吸尺寸范围内（例如小于约5微米）的液滴流，以便瞄准使用者的肺部系统。
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3.发明申请DROPLET DELIVERY DEVICE FOR DELIVERY OF FLUIDS TO THE PULMONARY SYSTEM AND METHODS OF USE 审中-公开用于向肺内输送流体的滴液输送装置和使用方法
公开(公告)号：WO2017192767A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030913
申请日：2017-05-03
Applicant: PNEUMA RESPIRATORY, INC.
Inventor： GERMINARIO, Louis Thomas , HEBRANK, John H. , HUNTER, Charles Eric , HUNTER, Jack C. , LI, Chengjie , MAURER, Christopher W.
Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 µm, so as to target the pulmonary system of the user.
Abstract translation: 公开了用于将精确和可重复的剂量输送到用于肺部使用的受试者的液滴输送装置和相关方法。 液滴输送装置包括壳体，贮存器和排出器机构，以及至少一个差压传感器。 当压差传感器感测到壳体内的预定压力变化时，液滴输送装置自动由使用者呼吸致动。 然后致动液滴输送装置以产生平均喷射液滴直径在可呼吸尺寸范围内（例如小于约5微米）的液滴流，以便瞄准使用者的肺部系统。
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