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公开(公告)号：WO2019224338A1
公开(公告)日：2019-11-28
申请号：PCT/EP2019/063418
申请日：2019-05-24
发明人： SHABAT, Doron , ROTH-KONFORTI, Michal Eli , HANANYA, Nir , GREEN, Ori , SPITZ, Urs , WICK, Lukas , IHSSEN, Julian , VORBERG, Raffael , CRIBIU, Riccardo , BABJAKOVÀ, Zuzana , YAO, Chunyan
IPC分类号： C07D321/00
摘要： The present invention relates to dioxetane compounds, their use in the detection of presence or absence, quantification and identification of microorganisms including bacteria, bacterial fragments (e.g., LPS, endotoxin), viruses, fungi as well as other pathogens by means of chemiluminescence and to corresponding methods.
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公开(公告)号：WO2019224339A1
公开(公告)日：2019-11-28
申请号：PCT/EP2019/063419
申请日：2019-05-24
发明人： IHSSEN, Julian , SPITZ, Urs , SHABAT, Doron , GREEN, Ori , HANANYA, Nir
IPC分类号： C07D321/00 , C07F5/04
摘要： The present invention relates to dioxetane compounds of Formula la or lb, a compound of Formula II and their applications.
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公开(公告)号：WO2017130191A1
公开(公告)日：2017-08-03
申请号：PCT/IL2017/050088
申请日：2017-01-24
发明人： SHABAT, Doron , SATCHI-FAINARO, Ronit , HANANYA, Nir , GREEN, Ori , EILON, Tal
CPC分类号： C07D321/00 , C07F5/025 , C07F7/1852 , C07F9/12 , C07F9/65512 , C07H15/203 , C07H15/26 , C09B11/24 , C09B23/0066 , C09B23/04 , C09B23/083 , C09K11/06
摘要： The present invention provides dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and π* acceptor group-containing dioxetane based chemiluminescence probes, and compositions thereof. The chemiluminescence probes disclosed are useful for both diagnostics and in vivo imaging.
摘要翻译： 本发明提供基于二氧杂环丁烷的化学发光探针，更具体地讲是基于荧光团栓的二氧杂环丁烷基化学发光探针和含有π*受体基团的二氧杂环丁烷基化学发光探针及其组合物。 所公开的化学发光探针可用于诊断和体内成像。
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