公开(公告)号：WO2016138504A1

公开(公告)日：2016-09-01

申请号：PCT/US2016/019978

申请日：2016-02-26

申请人： SQUAREX, LLC

发明人： MCTAVISH, Hugh

IPC分类号： A61K35/763 ,  A61K39/165 ,  A61K39/245 ,  A61P31/22 ,  C07K14/035 ,  C12N15/38 ,  G01N33/571

CPC分类号： A61K39/245 ,  A61K31/04 ,  A61K35/763 ,  A61K39/12 ,  A61K39/165 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/55511 ,  C07K14/035 ,  C12N2710/16611 ,  G01N33/571

摘要： A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.

摘要翻译： 提供了一种用于治疗单纯疱疹病毒（HSV）感染的方法，包括：（a）在HSV病变部位局部施用引起对患者的延迟型超敏反应（DTH）反应的物质，以在该位点诱导DTH应答 在一次或多次HSV感染爆发期间的病变。

公开(公告)号：WO2020055382A1

公开(公告)日：2020-03-19

申请号：PCT/US2018/050358

申请日：2018-09-11

申请人： SQUAREX, LLC

发明人： MCTAVISH, Hugh ,  HORN, Thomas, Dag

IPC分类号： A61K31/122 ,  A61K9/00 ,  A61P31/10 ,  A61P31/12 ,  A61P37/02

摘要： A method is presented for treating viral and fungal infections by applying a topical immunosensitizer to the skin of a person infected with a virus or fungus and in need of treatment for the viral or fungal infection. Methods of improving anti- viral and anti-fungal immunity are also presented, and methods of increasing PBMC interferon gamma expression in response to a viral or fungal immune stimulus.