公开(公告)号：WO2022233441A1

公开(公告)日：2022-11-10

申请号：PCT/EP2021/072613

申请日：2021-08-13

申请人： SYMRISE AG

发明人： MCSHEA, Andrew ,  NIELSEN, Katrina ,  HANS, Joachim ,  KNUPFER, Mirjam ,  STUHLMANN, Dominik ,  MEYER, Imke ,  SCHMIDT, Léa ,  MASSIRONI, Marco ,  BENATO, Francesca ,  ROSA, Sandro

IPC分类号： C12N1/06 ,  C12N1/20 ,  C12P1/04 ,  A61K8/99 ,  A61K35/747

摘要： Suggested is a bacterial ferment obtained by a method comprising the steps of a) Culturing Lactobacillus species in at least one growth medium for at least 24 hours; b) Separating the mixture via centrifugation; c) Adding lactic acid to the supernatant obtained from step b) in an amount sufficient to lower the pH value of the supernatant; d) Stabilizing the resulting mixture with the addition of at least one preservative and/or at least one multifunctional; e) Optionally filtering the mixture to remove any final precipitation.

公开(公告)号：WO2022223099A1

公开(公告)日：2022-10-27

申请号：PCT/EP2021/060135

申请日：2021-04-19

申请人： SYMRISE AG

发明人： REICHENBACH, Maria ,  HILLEBRAND, Nadine ,  TITZE, Nicole ,  BENATO, Francesca ,  MASSIRONI, Michele ,  MASSIRONI, Marco

IPC分类号： A61K31/352 ,  A61K31/355 ,  A61K31/045 ,  A61P17/00 ,  A61P17/08 ,  A61P17/16 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61K8/00 ,  A61P29/00 ,  A61P39/06 ,  A61K8/97 ,  A61P43/00

摘要： Suggested is a composition comprising or consisting of (a) Cannabidiol and optionally (b) Bisabolol for use as a medicament for prophylaxis and treatment of various dysfunctions of human skin triggered particularly by stress.