公开(公告)号：WO2017087026A1

公开(公告)日：2017-05-26

申请号：PCT/US2016/031958

申请日：2016-05-12

Applicant: SYNGENTA PARTICIPATIONS AG ,  SYNGENTA CROP PROTECTION, LLC

Inventor： FATORETTO, Julio ,  WEN, Zhimou ,  MATTHEWS, Phillip ,  CHEN, Jeng Shong

IPC: A01N37/18 ,  A01P7/04 ,  C07K14/195 ,  C07K14/32 ,  C12N15/82

CPC classification number: A01N63/00 ,  C07K14/325 ,  C12N15/8286 ,  Y02A40/162

Abstract: Artificially selected strains of insects from the genus Spodoptera exhibiting resistance to a Bacillus thuringiensis derived Vip3A protein are described. Methods for various uses of these strains are also described.

Abstract translation: 描述了对来自苏云金芽孢杆菌来源的Vip3A蛋白质表现出抗性的来自斜纹夜蛾属的人工选择的昆虫菌株。 还描述了这些菌株的各种用途的方法。

公开(公告)号：WO2016105696A1

公开(公告)日：2016-06-30

申请号：PCT/US2015/060989

申请日：2015-11-17

Applicant: SYNGENTA PARTICIPATIONS AG ,  SYNGENTA CROP PROTECTION LLC

Inventor： DONOHUE, Kevin V. ,  LIU, Renshui ,  CHEN, Jeng Shong

IPC: C12N15/113 ,  C12N15/82 ,  A01H5/00

CPC classification number: C12N15/113 ,  C12N15/8218 ,  C12N15/8286 ,  C12N2310/14 ,  Y02A40/162

Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules that capable of interfering with pest histone genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.

Abstract translation: 公开了对鞘翅目昆虫有毒的双链RNA分子。 特别地，提供了能够干扰害虫组蛋白基因并且对目标有害物质有毒的干扰RNA分子。 此外，公开了制备和使用干扰RNA的方法，例如在转基因植物中赋予防止昆虫损伤的方法。

公开(公告)号：WO2013015993A1

公开(公告)日：2013-01-31

申请号：PCT/US2012/046239

申请日：2012-07-11

Applicant: SYNGENTA PARTICIPATIONS AG ,  HUANG, Xiang ,  CHEN, Jeng Shong

Inventor： HUANG, Xiang ,  CHEN, Jeng Shong

IPC: C12N15/82 ,  A01N63/02 ,  A01H5/00

CPC classification number: A01N65/20 ,  A01N37/44 ,  A01N37/46 ,  C12N15/8261 ,  C12N15/8285 ,  Y02A40/146 ,  Y02A40/164

Abstract: Transgenic plants expressing a Vip3 protein have been found to be efficacious against plant-infesting nematodes. Disclosed are methods of controlling nematode populations using transgenic plants expressing Vip3 protein.

Abstract translation: 已发现表达Vip3蛋白的转基因植物对植物侵染线虫有效。 公开了使用表达Vip3蛋白的转基因植物控制线虫种群的方法。

公开(公告)号：WO2015128445A1

公开(公告)日：2015-09-03

申请号：PCT/EP2015/054100

申请日：2015-02-26

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： LIU, Renshui ,  JUCOVIC, Milan ,  SESSLER, Richard ,  TANG, Guo-Qing ,  CHEN, Jeng Shong

IPC: C12N15/82 ,  C07K14/435

CPC classification number: C07K14/43563 ,  A01N37/46 ,  A01N63/02 ,  C12N9/14 ,  C12N15/1037 ,  C12N15/8286 ,  G01N33/566 ,  G01N33/68 ,  G01N2333/705 ,  G01N2430/10 ,  G01N2500/04 ,  Y02A40/162

Abstract: This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.

Abstract translation: 本发明提供被鉴定为与Vip3毒素相互作用的多肽。 本发明还提供鉴定结合Vip3相互作用多肽的试剂的方法，所述试剂可以作为杀虫剂，细胞毒性剂和/或调节Vip3相互作用多肽的活性。

公开(公告)号：WO2013192256A1

公开(公告)日：2013-12-27

申请号：PCT/US2013/046450

申请日：2013-06-19

Applicant: SYNGENTA PARTICIPATIONS AG ,  DONOHUE, Kevin ,  LIU, Renshui ,  CHEN, Jeng Shong

Inventor： DONOHUE, Kevin ,  LIU, Renshui ,  CHEN, Jeng Shong

IPC: C12N15/82 ,  C12N15/11 ,  A01N63/02 ,  A01H5/00

CPC classification number: C12N15/8218 ,  A01N57/16 ,  A01N63/02 ,  C07K14/43563 ,  C12N15/113 ,  C12N15/1135 ,  C12N15/8286 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/3519 ,  C12N2310/531 ,  Y02A40/162

Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.

Abstract translation: 公开了对鞘翅目昆虫有毒的双链RNA分子。 特别地，提供了能够干扰害虫IAP基因并且对目标害虫有毒的dsRNA分子。 此外，公开了制备和使用干扰RNA的方法，例如在转基因植物中赋予防御昆虫损伤的方法。