公开(公告)号：WO1995013288A1

公开(公告)日：1995-05-18

申请号：PCT/US1994012985

申请日：1994-11-10

Applicant: THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY

Inventor： THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY ,  CLAYBERGER, Carol ,  KRENSKY, Alan, M.

IPC: C07K01/22

CPC classification number: G01N33/56977 ,  A61K38/00 ,  C07K14/705

Abstract: p74 is a protein found in T-cells and other cells, which when bound with specific agents results in inhibition of cytolytic activity and differentiation of CTLs. p74 can be isolated from T-cells and other cells using palindromic HLA-B2702.84-75-84 peptide by affinity binding of a cell lysate.

Abstract translation: p74是在T细胞和其他细胞中发现的蛋白质，当与特异性试剂结合导致CTL的细胞溶解活性和分化的抑制。 可以通过细胞裂解物的亲和结合使用回文HLA-B2702.84-75-84肽从T细胞和其它细胞中分离p74。