公开(公告)号：WO2016065312A1

公开(公告)日：2016-04-28

申请号：PCT/US2015/057202

申请日：2015-10-23

Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Inventor： HUH, Dongoun ,  SEO, Jeongyun

IPC: G09B23/30

CPC classification number: G09B23/32

Abstract: The presently disclosed subject provides a biomimetic eye model, and methods of its production and use. In one exemplary embodiment, the biomimetic eye model can include a scaffold having a convex curvature, a fluidic device coupled to the scaffold, a fabricated eyelid coupled to the fluidic device and a motor coupled to the fabricated eyelid. In certain embodiments, the scaffold can be impregnated with one or more keratocytes and a surface of the convex curvature of the scaffold can be covered with one or more layers of epithelial cells.

Abstract translation: 目前公开的主题提供仿生眼模型及其生产和使用的方法。 在一个示例性实施例中，仿生眼模型可以包括具有凸曲率的支架，耦合到支架的流体装置，耦合到流体装置的制造的眼睑和耦合到制造的眼睑的马达。 在某些实施方案中，支架可以用一个或多个角膜细胞浸渍，并且支架的凸曲面的表面可被一层或多层上皮细胞覆盖。