公开(公告)号：WO2015185534A1

公开(公告)日：2015-12-10

申请号：PCT/EP2015/062222

申请日：2015-06-02

Applicant: THERMO FISHER SCIENTIFIC BALTICS UAB

Inventor： ALZBUTAS, Gediminas ,  LAGUNAVIČIUS, Arūnas ,  KANIUŠAITĖ, Milda

IPC: C07K14/435

CPC classification number: C12N9/22 ,  C12Y301/21001

Abstract: Provided is a deoxyribonuclease comprising: (a) an amino acid sequence having at least 85% sequence identity with the sequence of a eukaryotic DNase I; and (b) an amino acid sequence capable of binding nucleic acid non-specifically comprising at least one helix-hairpin-helix motif.

Abstract translation: 提供了一种脱氧核糖核酸酶，其包含：（a）与真核生物DNA酶I的序列具有至少85％的序列同一性的氨基酸序列; 和（b）能够结合非特异性包含至少一个螺旋 - 发夹 - 螺旋基序的核酸的氨基酸序列。