公开(公告)号：WO2018134736A1

公开(公告)日：2018-07-26

申请号：PCT/IB2018/050274

申请日：2018-01-17

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： JUNG, Moon Chul ,  BELANGER, Jonathan L. ,  SONG, Xiangjin ,  TARAFDER, Abhijit ,  JARRELL, Joseph A. ,  LEVEILLE, SR., Wade P.

IPC: G01M3/20 ,  G01M3/26 ,  G01N30/02

CPC classification number: G01N30/88 ,  G01M3/202 ,  G01M3/26 ,  G01N30/02 ,  G01N30/04 ,  G01N30/26 ,  G01N30/6052 ,  G01N30/8675 ,  G01N2030/889

Abstract: Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. The leak detection system includes a sealable compartment disposed to surround at least one component of a chromatography system. The detector is in communication, e.g., fluid communication, with an interior of the sealable compartment and configured to detect the leak by various mean including the presence of liquid or the presence of vapor, or both within the sealable compartment.

公开(公告)号：WO2018134750A1

公开(公告)日：2018-07-26

申请号：PCT/IB2018/050293

申请日：2018-01-17

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： SONG, Xiangjin ,  MURPHY, James P. ,  FADGEN, Keith ,  LEVEILLE, Wade P., Sr. ,  MICHIENZI, Joseph D. ,  BELANGER, Jonathan L. ,  JUNG, Moon Chul ,  TARAFDER, Abhijit

IPC: G01N30/26 ,  G01N35/10 ,  G01N30/80

Abstract: Solvent containers and solvent container trays for chromatography systems are described for providing control over solvent supply and waste collection. Designated solvent containers and exclusively designated solvent containers provide solvents for use by chromatography systems. Control over solvent supply is achieved by requiring matched container shape and container receiving position shape within the tray, and additionally or alternatively, through solvent container coding readable by the solvent tray and chromatography system which provide information about the solvent container to the chromatography system.

公开(公告)号：WO2018134735A1

公开(公告)日：2018-07-26

申请号：PCT/IB2018/050273

申请日：2018-01-17

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： TARAFDER, Abhijit ,  JUNG, Moon Chul ,  BELANGER, Jonathan L. ,  SONG, Xiangjin ,  LEVEILLE, Wade P. ,  BROUSMICHE, Darryl W.

IPC: G01M3/04 ,  G01N30/02

Abstract: Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a detectable change when exposed to a chromatographic fluid or mobile phase. The change of the responsive material can indicate the presence of the fluid or mobile phase, a change in at least one physical property of the coating to prevent passage of the fluid or mobile phase, or a combination thereof.

公开(公告)号：WO2018134662A1

公开(公告)日：2018-07-26

申请号：PCT/IB2017/058166

申请日：2017-12-19

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： LEVEILLE, Wade P. ,  BELANGER, Jonathan L. ,  JUNG, Moon Chul ,  TARAFDER, Abhijit ,  MICHIENZI, Joseph ,  FADGEN, Keith ,  WYNDHAM, Kevin ,  SONG, Xiangjin

IPC: G01N30/32

Abstract: The present disclosure relates to methods and devices for providing pressurized solvent flow in chromatography systems. In one embodiment at least one divert valve is in fluid communication with at least one solvent source (Container); and a pump (LC Pump) is in fluid communication with the at least one divert valve, wherein the at least one divert valve is located in between the at least one solvent source and the pump, and wherein the at least one divert valve is adapted for diverting at least one solvent flow stream to the pump or to an auxiliary flow path.