摘要:
Systems, methods, and devices are provided for determining an impedance measurement of a sample of fluid on a test strip having a base layer, at least two drive electrodes disposed on the base layer and in electrical communication with a current-source (I ac ) for flowing an AC current provided by the current-source (I ac ) through a fluid sample between the at least two drive electrodes, and at least two sense electrodes disposed on the base layer and positioned between the at least two drive electrodes, each of the at least two sense electrodes configured for measuring a difference in an AC potential therebetween to determine an impedance measurement of the fluid sample between the at least two sense electrodes.
摘要:
An analyte measurement system is disclosed herein. The analyte measurement system includes a test strip. The test strip includes at least two electrodes spaced apart in a reaction chamber, one of said electrodes including a conductive material having a coating applied thereupon. The analyte measurement system also includes an analyte measurement device. The analyte measurement device includes a strip port having connectors configured to coupled to the electrodes of the test strip. The applied coating enables a capacitance value of the test strip to be measured in order to determine compatibility of the test strip with the analyte measurement device.
摘要:
A method of calibrating a device for measuring the concentration of creatinine using one or more calibration solutions, the method comprising: receiving concentrations at an initial time of creatine, Cr, and/or creatinine, Crn, of the one or more calibration solutions; receiving outputs of the measuring device at the end time; calculating the concentration of Cr and/or Cm in the calibration solutions at an end time using a temperature model, wherein the temperature model indicates changes in temperature of the calibration solutions from the initial time to the end time; and determining a relationship between the outputs of the measuring device and the calculated concentrations of Cr and/or Cm.
摘要:
A method for configuring a device to determine a concentration of an analyte, the method using a plurality of m fluid samples, each fluid sample of the m fluid samples having a corresponding known analyte concentration, the method comprising: for each fluid sample of the m fluid samples: generating an output signal from the fluid sample; recording values of the output signal over time; and modelling at least a subset of the recorded values of the output signal using n basis functions to obtain n coefficients, each coefficient being associated with a corresponding basis function, the n basis functions and n coefficients representing the output signal for the subset; performing a statistical analysis of the mxn coefficients and corresponding known analyte concentrations to determine a set of n parameters from which an analyte concentration can be estimated based on a set of n coefficients obtained for a fluid sample for which the analyte concentration is unknown; and storing the set of n parameters in a memory of one or more devices.
摘要:
The present invention relates to a method of detecting at least one analyte in a test sample, said method comprising the steps of a) contacting said test sample (i) to an active chemistry matrix (116) changing at least one electrochemical property dependent on an enzymatic activity active in the presence of said analyte, said active chemistry matrix contacting a first electrode (112); and (ii) to an inactive chemistry matrix (118), said inactive chemistry matrix contacting a second electrode (114), b) closing an electrical circuit including said first electrode(112), said second electrode (114), and said active chemistry matrix (116) and inactive chemistry matrix (118), followed by determining a first value of said at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of said at least one electrochemical property, and d) detecting said at least one analyte based on said first value and on said second value. Moreover, the present invention relates to a test device and to a test system adapted to make use of the method of the present invention. The present invention further relates to a sensor element (110) for determining at least one analyte, comprising a pair of electrodes (112, 114) and at least an active and an inactive chemistry matrix (116, 118), said active chemistry matrix (116) changing at least one electrochemical property dependent on an enzymatic activity active in the presence of said analyte, (i) wherein said pair of electrodes (112, 114) consists of two electrodes electrically insulated from other electrodes, (ii) wherein said active chemistry matrix (116) comprises said enzymatic activity and wherein said inactive chemistry matrix (118) does not comprise said enzymatic activity, and (iii) wherein a first electrode (112) of said pair of electrodes contacts said active chemistry matrix (116) and wherein a second electrode (114) of said pair of electrodes contacts said inactive chemistry matrix (118).
摘要:
A method of determining analyte concentration uses a redox reaction in an electrochemical cell that has at least two electrodes, one of which is a working electrode, at least one electrode being exposed to at least one redox mediator. The method uses at least one cycle of pulses, each cycle having at least a first potential and a second potential. The method comprises applying a first potential to initiate an accumulation phase that forces accumulation of a mediator concentration gradient at or close to the working electrode with a concentration that decreases towards the bulk solution, applying a second potential to initiate a measurement phase and deplete the established mediator concentration gradient at the working electrode, measuring current associated with the second potential of each cycle, and using the measured current to determine analyte concentration. In this way, the effects of diffusion interfering factors (DIF), especially haematocrit (Hct) can be mitigated.
摘要:
본 발명은 휴대용 혈당 측정기에 관한 것으로, 케이스의 일측면에 외부 온도 변화에 따라 신속하게 온도 변화하는 온도 측정 매개체를 외부 노출되게 장착하고, 온도 측정 매개체의 온도를 적외선 온도 센서로 비접촉 방식으로 측정하며, 측정된 온도를 고려하여 혈당 측정 결과를 산출함으로써, 실제 혈당 측정 환경의 외부 온도를 정확하게 반영할 수 있어 혈당 측정 결과의 정확도를 향상시킬 수 있고, 온도 측정 매개체를 케이스와는 독립적으로 외부 온도에 민감하게 반응하도록 구성함으로써, 외부 온도 변화에 따른 온도 측정 매개체의 온도 변화가 신속 정확하게 이루어지고, 이에 따라 더욱 정확한 온도 측정이 가능하고 이로 인해 더욱 정확하게 혈당 측정 결과를 산출할 수 있는 휴대용 혈당 측정기를 제공한다.
摘要:
A test sensor (100) for determining an analyte concentration in a biological fluid comprises a strip including a fluid receiving area (128) and a port-insertion region (126). A first row of optically transparent (132) and non-transparent positions forms a calibration code pattern (130) disposed within a first area of the port-insertion region (126). A second row of optically transparent (142) and non-transparent positions forms a synchronization code pattern (140) disposed within a second area of the port-insertion region (126). The second area is different from the first area. The synchronization code pattern (140) corresponds to the calibration code pattern (130) such that the synchronization code pattern (140) provides synchronization of the serial calibration code pattern (130) during insertion of the port- insertion region (126) into the receiving port of the analyte meter.
摘要:
A system for determining usability of an analytical test strip having two electrodes connected in series with a sample cell includes a test meter configured to receive the test strip. The sample cell receives a fluid sample, the sample cell with the received fluid sample having a frequency-dependent impedance. A microprocessor and circuit in the test meter cause application of an AC waveform across the sample cell via the electrodes upon detection of sample in the sample cell and concurrently measure of a current through the electrodes. The AC waveform has a frequency at which the characteristic impedance is substantially zero. The measured current is inversely proportional to a series resistance of the two electrodes. A hand-held test meter and a method for determining usability of an analytical test strip are also described.