公开(公告)号：WO2023069294A1

公开(公告)日：2023-04-27

申请号：PCT/US2022/046534

申请日：2022-10-13

Applicant: STEINBRONN, Joshua

Inventor： STEINBRONN, Joshua

IPC: A01N33/02 ,  A01G22/00 ,  A01N25/02 ,  A01P21/00

Abstract: A urea cycle augmenting composition for improving plant growth and yields and quality of crops includes a urea cycle augmenting composition, which comprises two or more of L-arginine, L-ornithine, L-aspartic acid, L-citrulline, L-argininosuccinic acid, and agmatine, or salts or derivatives thereof. An amount of the composition applied to a seed or a plant is sufficient to augment the urea cycle of a plant growing from the seed or the plant.

公开(公告)号：WO2022223620A1

公开(公告)日：2022-10-27

申请号：PCT/EP2022/060423

申请日：2022-04-20

Applicant: UNILEVER IP HOLDINGS B.V. ,  UNILEVER GLOBAL IP LIMITED ,  CONOPCO, INC., D/B/A UNILEVER

Inventor： IYER, Vidula ,  KHOKHAR, Jasmeet Kaur ,  MUKHERJEE, Sayandip ,  NEGI, Ajay Singh ,  PALANISAMY, Bharath ,  PATHAK, Sandip Bhanudas

IPC: A01N25/10 ,  A01N33/02 ,  A01P1/00

Abstract: The present invention relates to treating a surface with a polymer and compositions comprising it for preventing microbial reinfection especially that of virus and bacteria on the surface for a long period of time after the surface has been treated. The present invention also relates to certain liquid cleansing compositions, sanitizers, hand-held spray devices and towelettes comprising the polymer for delivering the above benefit.

公开(公告)号：WO2022005463A1

公开(公告)日：2022-01-06

申请号：PCT/US2020/040378

申请日：2020-06-30

Applicant: NATIONAL YANG-MING UNIVERSITY

Inventor： LEE, Yi-Hsuan ,  HUNG, Chia-Chi ,  HSU, Pei-Chien ,  HUANG, Yu-jie

IPC: A01N33/02 ,  A61K31/4045 ,  A61P25/00 ,  C12N5/02 ,  C12N5/079 ,  C12N5/0793 ,  C12N5/0006 ,  C12N5/06

Abstract: The present invention comprises a system and method for co-culturing glia cells and neurons in a combination of glia culture medium and neuron medium wherein the glia cells and neurons have cell morphology, cell reactions and/or cell interactions that exist in vivo after the co-culturing for up to about 21 days, up to about 30 days, up to about 40 days, up to about 45 days. Since the cell morphology, cell reaction and/or cell interaction of the co-culture are similar to those seen in vivo, the present system is capable of being configured as animal models for research, drug screening, testing and conducting clinical trials.

公开(公告)号：WO2021163269A1

公开(公告)日：2021-08-19

申请号：PCT/US2021/017575

申请日：2021-02-11

Applicant: RHODIA OPERATIONS ,  SEHGAL, Amit ,  GAGE, Laura ,  RAMDANI, Kamel

Inventor： SEHGAL, Amit ,  GAGE, Laura ,  RAMDANI, Kamel

IPC: A01N33/02 ,  A01N37/36 ,  A01N25/30 ,  A61L2/025 ,  A61L2/04 ,  A61L2/10

Abstract: The present disclosure provides a method for killing pathogens on a surface, the method comprising applying a composition to the surface, the composition comprising: at least one quaternary ammonium compound; a polymer comprising one or more types of monomer units selected from cationic monomer units, anionic monomer units, amphoteric monomer units, non-ionic monomer units, and combinations thereof, wherein at least one cationic monomer unit, amphoteric monomer unit or at least one anionic monomer unit is present when the polymer comprises one or more non-ionic monomer units; a surfactant selected from cationic surfactants, amphoteric surfactants, non-ionic surfactants, and combinations thereof; and, optionally, an organic acid, wherein the pH of the composition is less than 5; and the composition achieves at least 0.5 log reduction in the amount of live pathogens on the surface, wherein the pathogens are selected from bacterial spores, fungal spores, non-enveloped viruses and combinations thereof within about 60 minutes, under conditions of standard temperature and pressure.

公开(公告)号：WO2021150698A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/014343

申请日：2021-01-21

Applicant: EAST CAROLINA UNIVERSITY

Inventor： POKHREL, Lok Raj

IPC: B82B1/00 ,  B82B3/00 ,  A01N33/02 ,  A01N33/04 ,  A01N37/18 ,  A01N55/02

Abstract: The present inventive concept is related to metal nanoparticles, such as silver (Ag) nanoparticles, including a metal core and a surface to the metal core functionalized with a positively charged molecule/polymer coating the surface such as amino (–NH2), amide ([C=O]–N), polyethyleneimine/branched polyethyleneimine (PEI/BPEI), pesticidal compositions including the metal nanoparticle, and methods of using the pesticidal compositions including the metal nanoparticle.

公开(公告)号：WO2021038439A1

公开(公告)日：2021-03-04

申请号：PCT/IB2020/057936

申请日：2020-08-25

Applicant: ZISERMAN, Lior ,  ADAMA AGAN LTD. ,  MELIKER, Daniel ,  NAHMOUD, Sergio

Inventor： ZISERMAN, Lior ,  MELIKER, Daniel ,  NAHMOUD, Sergio

IPC: A01N25/02 ,  A01N33/02 ,  A01N33/12 ,  A01N43/54

Abstract: The present invention relates to a soluble liquid (SL) composition comprising saflufenacil and an organic base. Optionally, the composition further comprises at least one agriculturally acceptable carrier and/or additives. The present invention further relates to a use of an amine salt of saflufenacil for preparing a soluble liquid composition.

公开(公告)号：WO2020154724A1

公开(公告)日：2020-07-30

申请号：PCT/US2020/015197

申请日：2020-01-27

Applicant: VANDERBILT UNIVERSITY

Inventor： DIKALOV, Sergey I. ,  AMARNATH, Venkataraman

IPC: A01N33/02 ,  A61K31/13

Abstract: Compounds and methods for treating, preventing, and ameliorating at least one of vascular oxidative stress, improve vascular functions and/or reduce hypertension, comprising administering to a subject a compound that targets mitochondrial CypD to inhibit vascular oxidative stress, improve vascular functions and/or reduce hypertension.

公开(公告)号：WO2020093118A1

公开(公告)日：2020-05-14

申请号：PCT/BR2019/050021

申请日：2019-01-23

Applicant: WR INDUSTRIA E COMERCIO DE ELETRONICOS EIRELI ME

Inventor： OLIVEIRA, Willian

IPC: A01N25/00 ,  A01N33/02 ,  A61L101/18

Abstract: Uso de amônia para desinfecção de camas de aviários, seu processo e dispositivo de aplicação. A principal vantagem na utilização da amônia nesse processo de desinfecção é viabilizar a esterilização rápida dos microrganismos presentes no ambiente, em especial da Salmonella, permitindo a retomada da produção em períodos substancialmente menores do que na agropecuária contemporânea.

公开(公告)号：WO2017176780A1

公开(公告)日：2017-10-12

申请号：PCT/US2017/025977

申请日：2017-04-04

Applicant: HIGHER DIMENSION MATERIALS, INC.

Inventor： KIM, Young-Hwa ,  OLMSTED, Richard D. ,  JUBRAN, Nusrallah

IPC: A01N31/16 ,  A01N33/02 ,  A01N43/80 ,  A01N55/00 ,  A01N55/02 ,  A41D31/00 ,  A61K36/9066 ,  B32B5/02 ,  B32B3/08

Abstract: In some example, the disclosure relates to a fabric assembly comprising a flexible substrate including a top surface; a plurality of plates attached to the top surface of the flexible substrate and arrayed in a pattern such that a plurality of continuous gaps are defined between adjacent plates; and one or more antibacterial agents are contained in or on at least one of the substrate and the plurality of guard plates wherein the antimicrobial agents are selected to reduce the fabric assembly's surface population of at least one of bacteria, virus, mold, fungus, or algae.

Abstract translation: 在一些示例中，本公开涉及一种包括柔性衬底的织物组件，该柔性衬底包括顶部表面; 多个板，所述多个板附接到所述柔性衬底的顶表面并且以图案排列，使得在相邻板之间限定多个连续间隙; 并且一种或多种抗菌剂包含在所述基底和所述多个防护板中的至少一个之中或之上，其中选择所述抗微生物剂以减少细菌，病毒，霉菌，真菌或其组合中的至少一种的织物组件的表面群体 藻类。

公开(公告)号：WO2016186968A1

公开(公告)日：2016-11-24

申请号：PCT/US2016/032155

申请日：2016-05-12

Applicant: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

Inventor： SHERMAN, Scott ,  FALK, Torsten ,  ESTEVEZ, Miguel

IPC: A01N33/02 ,  A61K31/135

CPC classification number: A61K31/135 ,  A61K31/166 ,  A61K31/198 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/5415 ,  A61K31/551 ,  A61K31/5513 ,  A61K31/553 ,  A61K31/554 ,  A61K2300/00

Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明提供利用氯胺酮治疗运动障碍和/或与用于治疗运动障碍的某些药物相关的副作用的方法。 例如，在一些实施方案中，提供了通过施用一定剂量的氯胺酮或其药学上可接受的盐来治疗与向患有帕金森病的受试者施用左旋多巴有关的副作用的方法。 特别地，本发明提供了减少与运动障碍（例如帕金森病）治疗相关的运动障碍的方法，以及有效剂量的氯胺酮或其药学上可接受的盐。