公开(公告)号：WO2023081673A1

公开(公告)日：2023-05-11

申请号：PCT/US2022/079105

申请日：2022-11-02

Applicant: THE PROCTER & GAMBLE COMPANY

Inventor： GROTH, Andrew, Frederic ,  SAGEL, Paul, Albert ,  ST. JOHN, Samuel, James

IPC: A61K8/24 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/36 ,  A61K8/365 ,  A61K8/55 ,  A61K8/73 ,  A61Q11/00 ,  A61Q11/02

Abstract: Oral care compositions, such as whitening dentifrice compositions, whitening toothpaste compositions, and/or toothpaste compositions, include dicarboxylic acid, the dicarboxylic acid including malonic acid, methylmalonic acid, tartronic acid, malic acid, dimethylmalonic acid, mesoxalic acid, dihydroxymalonic acid, oxalic acid, salts thereof, or combinations thereof; and a pH of from about 4 to about 6, where the composition has a ChemPC ΔL of least about 7. Mouth rinse compositions include dicarboxylic acid, the dicarboxylic acid including malonic acid, methylmalonic acid, tartronic acid, malic acid, dimethylmalonic acid, mesoxalic acid, dihydroxymalonic acid, oxalic acid, salts thereof, or combinations thereof; a pH of from about 4 to about 6, and at least about 75%, by weight of the composition, of water, where the composition has a ChemPC ΔL of least about 7.

公开(公告)号：WO2023074675A1

公开(公告)日：2023-05-04

申请号：PCT/JP2022/039702

申请日：2022-10-25

Applicant: サンスター株式会社

Inventor： 犬伏　順也 ,  西村　佳祐 ,  清崎　若菜

IPC: A61K8/49 ,  A61K8/365 ,  A61K8/60 ,  A61K31/4425 ,  A61K31/704 ,  A61K47/12 ,  A61P1/02 ,  A61P31/04 ,  A61P43/00 ,  A61Q11/00

Abstract: 歯表面におけるプラークの形成やプラークの成熟化を抑制するための組成物が提供される。より具体的には、塩化ドデシルピリジニウムと、クエン酸及びその塩並びにグリチルリチン酸及びその塩からなる群より選択される少なくとも１種と、を含有する組成物が提供される。

公开(公告)号：WO2023069714A1

公开(公告)日：2023-04-27

申请号：PCT/US2022/047427

申请日：2022-10-21

Applicant: ZEST IP HOLDINGS, LLC

Inventor： LI, Yuping ,  ARALIS, Nicholas ,  GU, Wen

IPC: A61K8/04 ,  A61K8/22 ,  A61K8/81 ,  A61Q11/00

Abstract: Dental whitening compositions, kits and systems exhibiting stability in viscosity and hydrogen peroxide concentration for an extended shelf life without refrigeration or other special storage conditions are provided herein. The composition may be in gel form and comprise a hydrogen peroxide or a hydrogen peroxide precursor, and a thickening agent comprising a crosslinked and/or water insoluble N-vinyl heterocyclic homo- or copolymer. In some aspects, a kit may be provided comprising a two-part dental whitening system, wherein one part comprises a whitening agent, and a separate part comprises a strong base.

公开(公告)号：WO2023063180A1

公开(公告)日：2023-04-20

申请号：PCT/JP2022/037212

申请日：2022-10-05

Applicant: ライオン株式会社

Inventor： 今崎　麻里 ,  小熊　友一 ,  岩崎　彩佳 ,  橋本　匡太

IPC: A61K8/21 ,  A61K8/20 ,  A61K8/24 ,  A61K8/49 ,  A61K8/55 ,  A61Q11/00

Abstract: 口腔内の歯面及び口腔粘膜へのフッ素イオン滞留性に優れ、長期保存後も優れたフッ素イオン滞留性を与えるフッ素含有化合物含有の口腔用組成物を提供する。　（Ａ）縮合リン酸又はその塩、（Ｂ）カルシウム塩、（Ｃ）フッ素含有化合物、及び（Ｄ）ピロリドンカルボン酸又はその塩を含有する口腔用組成物。

公开(公告)号：WO2023036648A1

公开(公告)日：2023-03-16

申请号：PCT/EP2022/073960

申请日：2022-08-29

Applicant: BASF SE ,  BASF (CHINA) COMPANY LIMITED

Inventor： ZHOU, Hua ,  XU, Yu Ting ,  WANG, Yi Yao ,  ZHU, Ben Chuan ,  MEHLING, Annette

IPC: A61K8/44 ,  A61K8/60 ,  A61Q11/00

Abstract: The present invention relates to an oral care composition comprising at least one glycolipid and at least one surfactant selected from the group consisting of alkyl polyglycoside surfactant, carboxylated alkyl polyglycoside surfactant and N-acyl amino acid surfactant. The present invention also provides a method for removing and/or preventing dental plaque.

公开(公告)号：WO2023035387A1

公开(公告)日：2023-03-16

申请号：PCT/CN2021/128368

申请日：2021-11-03

Applicant: 重庆登康口腔护理用品股份有限公司

Inventor： 宫敬禹 ,  张旻 ,  邓全富 ,  张红 ,  陈凤 ,  邓嵘

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/46 ,  A61K8/60 ,  A61Q11/00

Abstract: 一种具有良好生物相容性的组合物，包括以下重量百分比的组分：表面活性剂0.5％～4％、锶盐1％～3.5％；其制备成的口腔制品还包括基质，基质包括保湿剂、摩擦剂、增稠剂、表面活性剂、甜味剂、防腐剂和香气调节剂，余量为水。制备方法包括如下步骤：加入保湿剂，再加入增稠剂搅拌均匀后，加入甜味剂、防腐剂，再加入具有良好生物相容性的组合物，充分搅拌，再加入摩擦剂和水，搅拌均匀后加入香气调节剂，充分搅拌，真空脱气，制膏完成。口腔制品生物相容性好，治疗牙本质敏感效果佳。

公开(公告)号：WO2023033535A1

公开(公告)日：2023-03-09

申请号：PCT/KR2022/013018

申请日：2022-08-31

Applicant: ANGIOLAB, INC.

Inventor： KIM, Min Young ,  PARK, Byung Young ,  CHO, Il Hwan ,  PARK, Eun Kyu

IPC: A61K36/185 ,  A61K31/7048 ,  A61P1/02 ,  A23L33/105 ,  A61K8/9789 ,  A61Q11/00

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating periodontal disease, comprising horse chestnut extract as effective component, and a food composition for preventing or improving periodontal disease, comprising horse chestnut extract as effective component, wherein the horse chestnut extract comprises avicularin and juglanin as active ingredients.

公开(公告)号：WO2023028179A1

公开(公告)日：2023-03-02

申请号：PCT/US2022/041426

申请日：2022-08-24

Applicant: GET-GRIN INC.

Inventor： SCHULHOF, Adam Benjamin ,  LIPNIK, Alon Luis ,  OREN-ARTZI, Pamela Sharon ,  EILAT-BLOCH, Yarden

IPC: A61Q11/02 ,  A61K8/18 ,  A61K8/30 ,  A61Q11/00

Abstract: Described herein are systems and methods for monitoring progress or predicting an outcome of a tooth whitening regimen, including a method to monitor progress or predict an outcome of a tooth whitening regimen, comprising: (a) providing an adapter comprising a viewing channel configured to define a field of view of an intraoral region of a subject's mouth, wherein one or more teeth are visible in the field of view of the subject's mouth; (b) providing a color reference target comprising one or more color samples, wherein the color reference target appears in the field of view of the subject's mouth, and wherein each of the one or more color samples is associated with a reference color or shade; (c) using the color reference target to identify the color or shade of the one or more teeth; and (d) predicting the outcome of the tooth whitening regimen based on the identified color or shade of the one or more teeth and, optionally, one or more properties of the one or more teeth.

公开(公告)号：WO2023020817A1

公开(公告)日：2023-02-23

申请号：PCT/EP2022/071514

申请日：2022-08-01

Applicant: UNILEVER IP HOLDINGS B.V. ,  UNILEVER GLOBAL IP LIMITED ,  CONOPCO, INC., D/B/A UNILEVER

Inventor： GAO, Long ,  JIN, Huajin ,  LIU, Weining ,  WANG, Jinfang

IPC: A61K8/46 ,  A61K8/49 ,  A61K8/73 ,  A61Q11/00

Abstract: An oral care composition is disclosed comprising iota carrageenan, kappa carrageenan, an anionic surfactant, and a pigment having a hue angle, h, in the CIELAB system of from 220 to 320 degrees, wherein the total amount of iota and kappa carrageenan to the amount of pigment is present in a weight ratio from 1 :5 to 100:1.

公开(公告)号：WO2023020801A1

公开(公告)日：2023-02-23

申请号：PCT/EP2022/071109

申请日：2022-07-27

Applicant: UNILEVER IP HOLDINGS B.V. ,  UNILEVER GLOBAL IP LIMITED ,  CONOPCO, INC., D/B/A UNILEVER

Inventor： LIU, Weining ,  WANG, Xiaohong

IPC: A61K8/44 ,  A61Q11/00

Abstract: Disclosed is a method for remineralizing teeth of an individual comprising the step of applying an uncharged polar amino acid and a charged polar amino acid in a composition to at least one surface of the teeth of the individual, wherein the uncharged polar amino acid comprises serine, tyrosine, threonine, cysteine, asparagine, glutamine or mixtures thereof.