申请号: EP83112325.2
申请日: 1983-12-08
公开(公告)号: EP0114277B1
公开(公告)日: 1987-02-04
发明人: Gay, John C.; McCurdy, H. Dennis; Rose, Wayne B.
更多申请号: EP83112325.2
申请日: 1983-12-08
公开(公告)号: EP0114277A1
公开(公告)日: 1984-08-01
发明人: Gay, John C.; McCurdy, H. Dennis; Rose, Wayne B.
A broad spectrum anthelmintic composition useful for eliminating nematodes and cestodes from carnivores. Composition comprises anthelmintically effective amounts of compounds which act systemically and via direct contact in carnivore gut, the compounds being carried in a vehicle which provides simultaneous systemic and direct contact availability of the compounds. Preferred composition comprises febantel and praziquantel compounds in an aqueous paste-like formulation.
申请号: US14083879
申请日: 2013-11-19
公开(公告)号: US09249102B2
公开(公告)日: 2016-02-02
发明人: Charles Q. Meng; Alan Long; Srinivas Reddy Gurrala; Douglas Edward Wilkinson
The present invention relates to novel anthelmintic compounds of formula (I) below: wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X1, X2, X3, X4, X5, X6, X7 and X8 are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.
更多申请号: US11253361
申请日: 1961-05-25
公开(公告)号: US3152041A
公开(公告)日: 1964-10-06
发明人: GILLINGHAM JAMES M; CLARK JOHN C
更多申请号: EP96932093.0
申请日: 1996-09-19
公开(公告)号: EP0873127A1
公开(公告)日: 1998-10-28
发明人: HARVEY, Colin Manson
A composition containing an anthelmintic chosen from the class of macrocyclic lactones including but not limited to the avermectins, ivermectin, doramectin, abamectin, milbemycin and moxidectin, together with a vegetable oil and a co-solvent chosen from the group comprising alcohols having four or more carbon atoms. The compositions of the invention may be formulated as injections, drenches or for topical administration and are suitable for treating helminthiasis in animals.
更多申请号: PCT/GB0100439
申请日: 2001-02-05
公开(公告)号: WO0157210A2
公开(公告)日: 2001-08-09
发明人: LU XINJIE; KAKKAR VIJAY VIR
The use of dendroaspin as a scaffold for one or more non-wild-type dendroaspin domains, the dendroaspin scaffold being modified in that the native RGD motif has been deleted or has been replaced by (i) an amino acid sequence having no integrin-binding activity or (ii) an integrin-binding amino acid sequence other than RGD which contains aspartic acid (D) or glutamic acid (E).
更多申请号: JP2016517393
申请日: 2014-09-26
公开(公告)号: JP2016537306A
公开(公告)日: 2016-12-01
发明人: ガッサー,ギレス; ビー. ガッサー,ロビン; ヘス,ジャニーヌ; ジャバー,アブダル; パトラ,マレー
本発明は一般式(1)【化1】[式中、OMは非置換若しくは置換された金属サンドイッチ化合物、非置換若しくは置換されたハーフ金属サンドイッチ化合物又は金属カルボニル化合物の群から独立して選択される有機金属化合物であり、かつ、RL及びRRの少なくとも1つが【化2】から選択されうる。]により特徴付けられる化合物、及び疾患の治療方法においてのそれらの使用、具体的には蠕虫に対する使用を含む。
更多申请号: EP03729158.0
申请日: 2003-05-28
公开(公告)号: EP1509514A1
公开(公告)日: 2005-03-02
发明人: LEE, Byung, H.; GEARY, Timothy, G.; DAVIS, John, P.; BOWMAN, Jerry, W.
Novel anthelmintic compositions containing thiophene derivatives as active ingredients are disclosed.
更多申请号: EP82300829.7
申请日: 1982-02-18
公开(公告)号: EP0059074B1
公开(公告)日: 1984-10-10
发明人: Kitano, Noritoshi Biological Research Laboratories
更多申请号: EP90910537.0
申请日: 1990-07-17
公开(公告)号: EP0486507A1
公开(公告)日: 1992-05-27
发明人: McGILLIVERY, Duncan, James; YONG, Weng, Kwong; RIFFKIN, George, Gerald; ADLER, Ben
Composition de vaccin utile au traitement des ascarides gastrointestinaux chez les mammifères. La composition de vaccin possède comme constituant antigène une fraction protéique d'à peu près 31 kD d'un extrait de Ostertagia circumcincta, de préférence à partir du troisième stade larvaire. On décrit l'administration de ce vaccin aux moutons ainsi que son effet sur ceux-ci.
更多申请号: US2210260
申请日: 1960-04-14
公开(公告)号: US3080282A
公开(公告)日: 1963-03-05
发明人: SHUNK CLIFFORD H
更多申请号: EP04758886.8
申请日: 2004-04-05
公开(公告)号: EP1610613B1
公开(公告)日: 2016-12-28
发明人: SOLL, Mark, D.; KUMAR, Krishan; WARANIS, Robert, P.; SHUB, Natalya
更多申请号: EP94912342.0
申请日: 1994-04-05
公开(公告)号: EP0692964A1
公开(公告)日: 1996-01-24
发明人: DRAKE, Kevin D.; PUCKETT, Wallace E.
The use of ionene polymers as anthelmintics is described. A composition for the treatment of helminth infections in an animal comprising an effective amount of at least one ionene polymer and a physiologically acceptable carrier other than water is disclosed. Also disclosed is a method for the treatment of a helminth infection in an animal.
更多申请号: EP97909831.6
申请日: 1997-05-29
公开(公告)号: EP0910574B1
公开(公告)日: 2003-01-02
发明人: GEARY, Timothy, G.; BOWMAN, Jerry, W.; FRIEDMAN, Alan, R.
The present invention provides a novel radioactive neuropeptide represented by the formula Lys-His-Glu-Tyr-I-Leu-Arg-Phe-amide. The invention also provides a method for detecting anthelmintic activity of a compound using the novel neuropeptide of the present invention in a receptor binding assay. The novel radioactive neuropeptide has potent bioactivity in Ascaris suum neuromuscular strips, and therefore is particularly useful for high volume screening for potential anthelmintic compounds.
更多申请号: EP11735482.9
申请日: 2011-06-10
公开(公告)号: EP2582370A1
公开(公告)日: 2013-04-24
发明人: KERBOEUF, Dominique; GUEGNARD, Fabrice
The invention relates to compositions containing flavones and anthelmintics and to the uses thereof for treating nematode-induced parasitoses.
更多申请号: EP04758886.8
申请日: 2004-04-05
公开(公告)号: EP1610613A2
公开(公告)日: 2006-01-04
发明人: SOLL, Mark, D.; KUMAR, Krishan; WARANIS, Robert, P.; SHUB, Natalya
This invention provides for inter alia, topical anthelmintic formulations which comprise a pharmaceutically active combination consisting of at least one macrocyclic compound and at least one compound selected from the group consisting of praziquantel, morantel and pyrantel, which are dissolved in a non-aqueous solvent or solvent mixture and optionally a thickening agent.
更多申请号: US156109
申请日: 1980-06-03
公开(公告)号: US4299837A
公开(公告)日: 1981-11-10
发明人: Paolo Piccardi; Giovanni Confalonieri; Lino Da Col; Pier G. Ramella
Benzimidazole-carbamates endowed wth anthelmintic activity, and substituted in position 5(6) by a diene chain bound to the position 5(6) by an oxygen or sulphur atom optionally oxidized, are described.The processes for their preparation, the intermediates thereof, and their use as anthelmintics are described too.
更多申请号: PCT/EP1996004918
申请日: 1996-11-11
公开(公告)号: WO1997019107A1
公开(公告)日: 1997-05-29
发明人: BAYER AKTIENGESELLSCHAFT; MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V., BERLIN
The invention concerns antigenes isolated from nematodes in essentially pure form and which show an immunological reaction with a protective anti-serum used against nematode larvae at the skin-shedding stage from L3 to L4, the antigenes being obtained by the in vitro cultivation of nematode larvae in the L4 stage and extraction from the surplus culture. The invention also concerns a method of obtaining such antigenes and their use in the development of new anthelmintics and vaccines.
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