US08247890B2
A conductor layer 2 is formed as a circuit pattern on a base insulating layer 1, a terminal 3 is formed thereon, and a supporting column 4 is formed in the vicinity of the terminal on the upper face of the base insulating layer 1. Here, supposing the protrusion height B of the bump from the element to be connected is B, the height of the supporting column is H, the height of the terminal is h, and the layer thickness of the terminal is t, as measured from the upper face of the base insulating layer as the reference surface, the height H of the supporting column is determined to satisfy B
US08247887B1
An optical device, e.g., LED, laser. The device includes a non-polar gallium nitride substrate member having a slightly off-axis non-polar oriented crystalline surface plane. In a specific embodiment, the slightly off-axis non-polar oriented crystalline surface plane is up to about −0.6 degrees in a c-plane direction, but can be others. In a specific embodiment, the present invention provides a gallium nitride containing epitaxial layer formed overlying the slightly off-axis non-polar oriented crystalline surface plane. In a specific embodiment, the device includes a surface region overlying the gallium nitride epitaxial layer that is substantially free of hillocks.
US08247882B2
Provided is a method of fabricating a semiconductor device that includes providing a semiconductor substrate having a front side and a back side, forming a first circuit and a second circuit at the front side of the semiconductor substrate, bonding the front side of the semiconductor substrate to a carrier substrate, thinning the semiconductor substrate from the back side, and forming an trench from the back side to the front side of the semiconductor substrate to isolate the first circuit from the second circuit.
US08247876B2
A seal ring structure is formed through a multilayer structure of a plurality of dielectric films in a peripheral part of a chip region to surround the chip region. A dual damascene interconnect in which an interconnect and a plug connected to the interconnect are integrated is formed in at least one of the dielectric films in the chip region. Part of the seal ring structure formed in the dielectric film in which the dual damascene interconnect is formed is continuous. A protection film formed on the multilayer structure has an opening on the seal ring. A cap layer connected to the seal ring is formed in the opening.
US08247867B2
A semiconductor device includes a base layer that has a first conductivity type, a source layer that is formed on the base layer and has a second conductivity type, and an insulating film that is formed on the source layer. The semiconductor device further includes a plurality of gate structures that penetrate the base layer, and a plurality of conductive parts that penetrate the insulating film and the source layer and electrically connect the source layer and the base layer to each other. The gate structures are formed in a stripe shape in plan view. Parts in which the conductive portion is connected to the base layer are formed in a stripe shape in plan view, and are formed between the gate structures. Further, a dimension of the part in which the source layer and the base layer are in contact with each other between the gate structure and the conductive portion is 0.36 μm or more.
US08247859B2
A semiconductor device includes an isolation layer defining an active region formed in a semiconductor substrate. A first recessing process is performed on the isolation layer to expose edge portions of the active region. A first rounding process is performed to round the edge portions of the active region. A second recessing process is performed on the isolation layer. A second rounding process is performed to round the edge portions of the active region.
US08247855B2
A ferroelectric device employs ferroelectric electrodes as local interconnect(s). One or more circuit features are formed within or on a semiconductor body. A first dielectric layer is formed over the semiconductor body. Lower contacts are formed within the first dielectric layer. A bottom electrode is formed over the first dielectric layer and on the lower contacts. A ferroelectric layer is formed on the bottom electrode. A top electrode is formed on the ferroelectric layer. A second dielectric layer is formed over the first dielectric layer. Upper contacts are formed within the second dielectric layer and in contact with the top electrode. Conductive features are formed on the upper contacts.
US08247852B2
A backside illuminated imaging sensor with reinforced pad structure includes a device layer, a metal stack, an opening and a frame. The device layer has an imaging array formed in a front side of the device layer and the imaging array is adapted to receive light from a back side of the device layer. The metal stack is coupled to the front side of the device layer where the metal stack includes at least one metal interconnect layer having a metal pad. The opening extends from the back side of the device layer to the metal pad to expose the metal pad for wire bonding. The frame is disposed within the opening to structurally reinforce the metal pad.
US08247838B2
A light emitting diode and a fabricating method thereof are provided. The method including the steps of sequentially forming a first-type semiconductor layer, a light emitting layer and a second-type semiconductor layer with a first region and a second region on a substrate. Next, an ion implantation process is performed to make the resistance of the first region be larger than of the second region. Afterward, a first electrode is formed above the first region of the second-type semiconductor layer. Since the method uses the ion implantation process to make the inner resistance of the second-type semiconductor layer various, the light emitting intensity and efficiency may both be increased.
US08247835B2
An LED package with an extended top electrode and an extended bottom electrode is made from a single metal sheet, one manufacturing process embodiment includes: preparing a piece of single metal sheet, forming a first metal and a coplanar second metal, mounting an LED on an inner end of the first metal, wire-bonding top electrode to an inner end of the second metal, encapsulating at least the LED and the bonding wire with a protection glue, bending an outer end of the first metal upward twice 90 degrees to form a top flat as an extended top electrode of the package, and bending an outer end of the second metal downward twice 90 degrees to form a bottom flat as an extended bottom electrode of the package.
US08247834B2
A light-emitting diode includes a substrate, a buffer layer on the substrate, a first semiconductor layer on the buffer layer, a light-emitting layer on the first semiconductor layer, a second semiconductor layer on the light-emitting layer, wherein the first semiconductor layer is partially exposed through the second semiconductor layer and the light-emitting layer, a first electrode on the exposed first semiconductor layer, and a second electrode on the second semiconductor layer, the second electrode having a grid shape.
US08247831B2
A side-emitting light emitting device (100) is provided, comprising a substrate (101), a reflector (102) arranged spaced apart from said substrate (101) and extending along the extension of said substrate, and at least one light emitting diode (103) arranged on said substrate and facing said reflector, said substrate (101) and reflector (102) delimiting a wave guiding region (104) for light emitted by said at least one light emitting diode (103). Further, a wavelength converting material (105) is arranged at the lateral edge of said wave guiding region (104). The invention provides a compact side emitter with controlled color emission.
US08247830B2
A light-emitting device package structure includes a leadframe, a light-emitting device disposed on the leadframe, a plurality of wires electrically connecting the leadframe and the light-emitting device, and an encapsulant covering the light-emitting device, the wires and a part of the leadframe. The encapsulant has a gas space therein, and the gas space is disposed on the light-emitting device, wherein the gas space includes at least one gas.
US08247829B2
Provided is a light emitting device. The light emitting device comprises a body, a light emitting diode on the body, a resistor integrated on the body and configured to sense a temperature of the light emitting diode, and a plurality of metal layers on the body.
US08247827B2
LED phosphor deposition for use with LEDs. In an aspect, a method is provided for forming an encapsulation. The method includes determining a geometric shape for the encapsulation, selecting a dam material, applying the dam material to a substrate to form a boundary defining a region having the geometric shape, and filling the region with encapsulation material to form the encapsulation. In another aspect, an LED apparatus is provided that includes at least one LED chip and an encapsulation disposed on the at least one LED chip. The encapsulation is formed by determining a geometric shape for the encapsulation, selecting a dam material, applying the dam material to a substrate to form a boundary defining a region having the geometric shape, and filling the region with encapsulation material to form the encapsulation.
US08247822B2
A semiconductor light-emitting device comprises a substrate, a first conductive type semiconductor layer positioned on the substrate, a light-emitting structure positioned on the first conductive type semiconductor layer, and a second conductive type semiconductor layer positioned on the light-emitting structure. The substrate includes an upper surface and a plurality of protrusions positioned on the upper surface. Each of the protrusions includes a top surface, a plurality of wall surfaces, and a plurality of inclined surfaces sandwiched between the top surface and the wall surfaces.
US08247820B2
The present invention relates to an electro-optical device, wherein the device is a light source, for example an OLED. The OLED includes at least a substrate, a cathode, an anode, one or more organic light-emissive materials disposed between the cathode and anode, and a gradient refractive index film disposed on an external, light emitting surface of the device, for example on the substrate layer. Alternatively, the device may be constructed with the gradient refractive index film as the substrate, and/or the gradient refractive index film may be applied to more than one light-emitting surface of a device.
US08247804B2
Disclosed is a light-emitting element with a good carrier balance and manufacturing method thereof which does not require the formation of the heterostructure. The light-emitting element includes an organic compound film containing a first organic compound as the main component (base material) between an anode and a cathode, wherein the organic compound film is provided in contact with the anode and with the cathode. The first organic compound further includes a light-emitting region to which a light-emitting substance is added and includes a hole-transport region to which a hole-trapping substance is added and/or an electron-transport region to which an electron-trapping substance is added. The hole-transport region is located between the light-emitting region and the anode, and the electron-transport region is located between the light-emitting region and the cathode.
US08247800B2
A conjugated or partially conjugated polymer including a structural unit of Formula I in the backbone: (Formula I), wherein Arl, Are are each independently a substituted or unsubstituted arylene or hetero arylene group with two or more aromatic rings fused together and Ar3 is an aryl or heteroaryl group of C4 to C40 or substituted aryl or heteroaryl group of C4 to C40 and devices containing such polymer. In addition, a composition of: (Formula V), wherein Ar1, Are are arylene or heteroaryl groups and Ar3 is an aryl or heteroaryl group and wherein X is a leaving group such as halogen, boronic acid or boronate ester.
US08247796B2
A semiconductor device includes a substrate, a superlattice buffer layer that is formed on the substrate and is composed of first AlxGa1-xN layers and second AlxGa1-xN layers having an Al composition greater than that of the first AlxGa1-xN layers, the first and second AlxGa1-xN layers being alternately stacked one by one, both the Al compositions of the first and second AlxGa1-xN layers being greater than 0.3, and a difference in Al composition between the first and second AlxGa1-xN layers being greater than 0 and smaller than 0.6.
US08247792B2
A light emitting diode (LED) having a modulation doped layer. The LED comprises an n-type contact layer, a p-type contact layer and an active region of a multiple quantum well structure having an InGaN well layer. The n-type contact layer comprises a first modulation doped layer and a second modulation doped layer, each having InGaN layers doped with a high concentration of n-type impurity and low concentration of n-type impurity InGaN layers alternately laminated. The InGaN layers of the first modulation doped layer have the same composition, and the InGaN layers of the second modulation doped layer have the same composition. The second modulation doped layer is interposed between the first modulation doped layer and the active region, and an n-electrode is in contact with the first modulation doped layer. Accordingly, an increase in process time is prevented and strains induced in a multiple quantum well structure are reduced.
US08247777B2
A method and system for reducing scintillator afterglow. Methods for reducing afterglow include conditioning a scintillator by exposing it to high flux densities of ionizing radiation. One technique includes operating an x-ray tube at elevated amperage.
US08247758B2
A user navigational apparatus. The user navigational apparatus includes a dial, a coding element, and an encoder. The coding element is coupled to a dial. The coding element includes a track of alternating reflective and non-reflective sections, each having a substantially oblique leading edge relative to a direction of movement of the coding element. The encoder includes an emitter and a detector. The emitter generates a light signal incident on the track of the coding element. The detector detects a reflected light signal which corresponds to a portion of the incident light signal that is reflected off of the reflective sections of the track. The detector also generates a channel signal corresponding to the reflected light signal.
US08247737B2
A contact fitting for a welding apparatus includes a housing, and first contact device, a second contact device, and a third contact device arranged between the first and second contact devices. The third contact device is movable relative to the first and second contact devices. The first contact device has an elongated form, is fixedly arranged in the housing, and extends from a first end, which is arranged between first and second ends of the housing, to a second end. The second contact device has an elongated form, is suspended spring-loaded to the housing, and extends from a first end, which is arranged between the first and second ends of the housing, to a second end.
US08247736B2
An apparatus for forming a pattern is provided. The apparatus includes a pattern storing unit, a controller, a laser oscillating unit, an X-Y driver, a header unit, and a stage. The pattern storing unit stores data on a light guide pattern. The controller reads out the data on the light guide pattern, and transmits a position signal of each light guide pattern to the X-Y driver and simultaneously, transmits a switching signal to the laser oscillating unit. The laser oscillating unit outputs a laser beam synchronized with a movement of a header unit. The X-Y driver moves the header unit and the stage. The header unit moves along a fixed first guide rail in the left and right direction of the light guide panel. The stage moves along a fixed second guide rail in the front and rear direction of the light guide panel.
US08247735B2
The invention relates to an installation that is used to perform operations for forming glass or crystal pieces (21), comprising: at least one drive wheel and at least one idler wheel (3); a support element which is driven by the drive wheel; main mandrels (7) which are supported by the support element and which, in turn, each support a first end of a glass or crystal piece (21); and work stations. According to the invention, at least one wheel takes the form of a carousel (2) which comprises secondary mandrels (8), numbering fewer than the main mandrels (7), and which co-operates with the moving support element. Each secondary mandrel (8) opposes a main mandrel (7) along a common axis (23) and supports the second end of the glass or crystal piece.
US08247733B2
An arrangement for the repair of BLISK blades damaged at their leading and trailing edges by use of laser deposition welding, includes a laser source and laser optics for generating a focused laser beam (26) and a powder line (35) connected to a powder reservoir for supplying metal powder to be melted by the laser beam to the weld area. A modular, tubularly elongated welding apparatus (7) with a connection module (13) which is connected to a laser source and in which the entering laser beam is deflected in longitudinal direction and parallelized, and to the one side of the connection module (13) is connected to a camera module for a CCD camera (12) enabling the precise positioning of the welding apparatus and the deposition of the molten metal powder on the respective blade to be monitored and controlled.
US08247728B2
An apparatus and method of bonding refractory metal alloys together by use of a modified clamping arrangement.
US08247727B2
An electrical switching apparatus includes separable contacts, an operating mechanism structured to open and close the separable contacts, and an arc chamber. The arc chamber includes a slot motor having a core and a housing with an opening therein, an arc chute, and a number of gassing inserts disposed in the opening of the housing. The number of gassing inserts and the housing are structured to form a number of gas flow circulation paths. The number of gas flow circulation paths are structured to drive an arc into the arc chute.
US08247724B2
A chute for inspection and sorting apparatus has first and second flat sections, with the lower end of the first section being disposed over the second section to form a step from which product falls onto the second section. Additional sections may be included. In one variant a third channeled section is included, with the lower end of the second section being disposed over the third section forming a second step from which product falls onto the third section.
US08247720B2
A sealed pushbutton switch includes an insulative housing defining a cavity, an actuator moveably retained in the insulative housing, a base conglutinated to the insulative housing by glue, a number of fixed contacts assembled to the base, a spring mounted below the actuator, and a moveable contact mounted on the actuator and provided with a number of contact portions in contact with corresponding fixed contacts. The moveable contact is moveable with the actuator from a first position to a second position relative to the insulative housing along a top-to-bottom direction to disengage the fixed contacts. The base defines a first slot formed along an edge of a inner face of said base and a second slot formed on a position of the inner face except the edge, the second slot have a connection with the first slot so as to retain glue therein when said base and said housing are fastened together by said glue.
US08247719B2
A button device includes a button unit, a resilient member, and a switch unit. The button unit includes a button, a transparent power icon member, and a retaining member. The power iron member is attached to the button. The retaining member includes an elastic element, a tray located at one end of the elastic element, and a fixing loop located at the other end of the elastic element. The button and the power iron member are retained on the tray. The tray includes a seat with a hole for receiving an illuminator, and reflects lights of the illuminator to the power icon member. The resilient member is sandwiched between the button unit and the switch unit to reset the button unit back to its original position.
US08247716B2
A position indicator assembly is provided for a levering assembly of an electrical switching apparatus, such as a circuit breaker. The levering assembly includes a drive shaft and a racking member movably coupled to the circuit breaker housing. The drive shaft cooperates with the racking member to facilitate racking the circuit breaker into and out of a cassette. The position indicator assembly includes a number of indicator gears cooperating with the drive shaft, an indication rack cooperating with the indicator gears, and an indicator cooperating with the indication rack to provide a visual indication indicative of the position of the circuit breaker with respect to the cassette. When the circuit breaker is moved with respect to the cassette, the drive shaft pivots. In response, the indicator gears move, thereby moving the indication rack and the indicator in order to provide the visual indication.
US08247713B2
A power seat switch includes a structure main body; switches provided in the structure main body; sliders slidably provided in the structure main body and changing over contacts of the switches; and moderation units each including a moderation adjuster fitted into the structure main body and an elastic portion provided on the slider. Each slider includes a shaft and a pair of legs provided on one end of the shaft. The elastic portion is provided to elastically protrude from the one end of the shaft in an axial direction of the shaft. The moderation adjuster includes a moderation groove arranged to be sandwiched between the legs, in contact with the elastic portion, and applying a moderation according to sliding of the slider.
US08247712B2
A coordinate inputting device includes an X+ electrode having a plurality of X+ branch patterns extending from one side to the other side in the X direction, an X− electrode having a plurality of X− branch patterns extending from one side to the other side in the X direction, a Y+ electrode having a plurality of Y+ branch patterns extending from one side to another side in the Y direction, and a Y− electrode having a plurality of Y− branch patterns extending from one side to the other side in the Y direction. An X, Y coordinate position of an object is detected from, respectively, the difference between the floating capacitances of the X+ electrode and X− electrode, and the difference between the floating capacitances of Y+ electrode and Y− electrode, which change according to the surface area of the electrodes in proximity to the object to be detected.
US08247708B1
Signals entering outside plant (OSP) telecommunications enclosures typically do so through weather tight connectors, with one connector mounted to the enclosure and a mating connector connected to a cable bringing the signals to the OSP housing. Such connectors are expensive and require extensive effort to connect the wires of a cable bundle to the connectors. These problems are avoided by allowing cables pre-installed with a cable seal and pre-terminated to cable connectors to pass through an opening in the wall of an OSP housing and seal the cable bundle to the housing to prevent the ingress of environmental elements into the housing through the opening. This permits easier installation and retrofitting of electronic equipment contained within the housing.
US08247706B2
An enclosure of an electronic device includes an upper shell, a lower shell mounted to the upper shell, and an electrical outlet mounted to the lower shell. The lower shell includes a front plate defining an opening. The electrical outlet includes a connector and a number of wires electrically connected to the connector. An electromagnetic interference absorbing magnetic ring fits about some of the wires. The lower shell further defines a cable channel extending through an edge of the front plate and communicating with the opening. The wires pass through the cable channel and extend through the opening to enter into the lower shell, with the connector covering the opening.
US08247703B2
A method of making a circuitized substrate including a resistor comprised of material which includes a polymer resin and a quantity of nano-powders including a mixture of at least one metal component and at least one ceramic component. The ceramic component may be a ferroelectric ceramic and/or a high surface area ceramic and/or a transparent oxide and/or a dope manganite. Alternatively, the material will include the polymer resin and nano-powders, with the nano-powders comprising at least one metal coated ceramic and/or at least one oxide coated metal component. An electrical assembly (substrate and at least one electrical component) and an information handling system (e.g., personal computer) utilizing such a circuitized substrate are also provided.
US08247695B2
A high frequency (HF) leakage current return wire-contained motor drive cable configured in a manner that one or multiple drive dielectric core wires and one or multiple HF leakage current return wires are arranged adjacent to and in close contact. Concurrently, the drive dielectric core wires and the HF leakage current return wires are arranged substantially parallel to the longitudinal direction and are stranded; and a sheath is provided without a shield being provided outside of the strand wires.
US08247694B2
A curved wall portion along which a wiring harness is bendably extended has a foreign-matter-escape side opening, at one wall continuing to a top opening of an upward guiding cylinder of a protector. A foreign-matter-escape side opening on the other wall of the cylinder proximate to the opening is opposed to the curved wall portion. A projection on the other wall in the guiding cylinder and below the side opening of the wall has an upwardly sloping surface continuing thereto. A projection in the guiding cylinder is above the side opening of the other wall, traversing the cylinder. The protector includes one separate protector member and the other separate protector member, the former having a projection extending toward the latter to cover a joining area thereof.
US08247689B2
The present invention relates to a ruthenium complex and a photoelectric component using the same, and the ruthenium complex is represented by the following formula (I): RuL2(NCS)2Am (I) wherein L, A and m are defined the same as the specification. The ruthenium complex of the present invention is suitable for Dye-Sensitized Solar Cell (DSSC). Hence, the photoelectric characteristics of the DSSC manufactured with the ruthenium complex of the present invention can be improved.
US08247688B2
In various embodiments, fiber photovoltaic devices are described in the present disclosure. The fiber photovoltaic devices include an optical filament, a first electrode coating the optical filament, a continuous semiconductive layer deposited above the first electrode layer, and a second electrode layer deposited above the continuous semiconductive layer. The first electrode layer is at least partially transparent to electromagnetic radiation. The continuous semiconductive layer is in electrical contact with the first electrode layer. The continuous semiconductive layer absorbs electromagnetic radiation and turns the electromagnetic radiation into an electrical signal. The continuous semiconductive layer includes at least two semiconductive materials that are substantially unmixed and are located in separate regions along the longitudinal axis of the fiber photovoltaic device. The second electrode layer is in electrical contact with the continuous semiconductive layer. In various embodiments, photovoltaic collectors including a plurality of the fiber photovoltaic devices are described. In various embodiments, methods for production of fiber photovoltaic devices by a dip coating technique are described.
US08247676B2
Methods for generating music are disclosed. A music data file is generated at a first node. The music data file is transmitted from the first node and received at a second node. Musical definition data that provides information regarding a data structure and data for musical parameters is extracted from the music data file at the second node. The musical definition data is processed and music is generated at the second node for playback in accordance with the data structure and the musical parameters. A modified music data file is generated at the second node and transmitted to the first node. Modified music is generated at the first node based on the modified music data file.
US08247674B2
A slide bar holder removably secures a slide bar to a stringed musical instrument. The slide bar holder includes an instrument attachment clip and a slide bar clip. The instrument attachment clip has an elongate central portion and a pair of opposing jaws disposed at opposite ends of the central portion which extend from the central portion in a first direction. The jaws of the instrument attachment clip are operable to removably receive the body portion of the musical instrument and thereby secure the slide bar holder to the musical instrument. The slide bar clip has a pair of opposing jaws that extend from the central portion of the instrument attachment clip in a second direction that is opposite the first direction. The jaws of the slide bar clip are spaced apart by a distance substantially equivalent to the diameter of the slide bar, such that the jaws of the slide bar clip are operable to removably receive and secure the slide bar in the slide bar holder.
US08247668B1
A novel maize variety designated X05A930 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X05A930 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X05A930 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X05A930, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X05A930. This invention further relates to methods for producing maize varieties derived from maize variety X05A930.
US08247667B1
A novel maize variety designated X03A115 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03A115 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03A115 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03A115, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03A115. This invention further relates to methods for producing maize varieties derived from maize variety X03A115.
US08247660B1
A soybean cultivar designated 04324131 is disclosed. The invention relates to the seeds of soybean cultivar 04324131, to the plants of soybean cultivar 04324131, to the plant parts of soybean cultivar 04324131, and to methods for producing progeny of soybean cultivar 04324131. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 04324131. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 04324131, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 04324131 with another soybean cultivar.
US08247645B2
A method for producing a Cucumis sativus plant, providing cucumber fruits exhibiting “extended shelf life, comprising: (a) providing a first Cucumis sativus plant containing at least one quantitative trait locus (QTL); (b) crossing the first plant with a second Cucumis sativus plant; (c) analyzing the progeny for presence or absence of QTL; and (d) identifying and selecting plants containing QTL. The QTL is selected from QTL1 or QTL2. QTL1 has a first molecular marker of SEQ ID No:1, a cucumber genomic fragment, and SEQ ID No:2, and a second molecular marker of SEQ ID No:3, a cucumber genomic fragment, and SEQ ID No:4. QTL2 has a first molecular marker of SEQ ID No:5, a cucumber genomic fragment, and SEQ ID No:6, and a second molecular marker of SEQ ID No:7, a cucumber genomic fragment, and SEQ ID No:8.
US08247644B2
The present invention is a method for manufacturing an animal model for researching a pulmonary tumor and a use thereof. A transgenic non-human animal of the present invention is prepared by embryonic gene microinjection and possesses a tissue-specific expression of vascular endothelial growth factor A165 (VEGF-A165) in lung. Through the expression of vascular endothelial growth factor A165, the lung cells in the transgenic non-human animal of the present invention have inflammatory, vascularogenesis and angiogenesis responses or induce lung tumors. Thus, the non-human animal of the present invention can serve as an animal model for analyzing the regulation and the anti-tumor drugs screening of pulmonary adenocarcinoma.
US08247636B2
To ensure an excellent slip-proof effect for a hygiene item, in particular for a baby diaper or an incontinence diaper when opening the diaper, a fastening tape is proposed having a separate film-like grip area with a macroscopically structured surface. Likewise, a hygiene item having such a grip area and a method for manufacturing such a fastening tape are proposed.
US08247628B2
A process for reacting an iso-alkane, comprising: a) partially converting one or more olefins in an olefinic feedstock with an ionic liquid catalyst to make a converted olefinic feedstock; and b) alkylating the iso-alkane with the converted olefinic feedstock, wherein a reaction heat that is evolved during the alkylating is at least 20% less than if the alkylating step is done with the iso-alkane and the olefinic feedstock without the partially converting step. Also, a process for reacting an iso-alkane, comprising: a) partially converting one or more olefins in an olefinic feedstock to make a converted olefinic feedstock, wherein the converting is different from isomerization; b) isolating from the converted olefinic feedstock: i. an enriched feed that has linear internal olefins, and ii. products having a boiling point of 150° C. or higher; and c) alkylating the iso-alkane with the enriched feed to make an alkylate gasoline blending component.
US08247620B2
A process for preparing highly pure hydroquinone freed of the impurities resulting from the production thereof includes at least the following steps: a) the crude hydroquinone in a liquid form and comprising at least resorcin and pyrogallol as impurities is subjected to a controlled cooling ensuring the crystallization of pure hydroquinone, b) the pure hydroquinone crystals are separated from the mother liquors, c) heating and partial melting thereof is next is carried out, d) the purified hydroquinone is then completely melted, and e) the purified hydroquinone is recovered.
US08247617B2
Novel Sr and Ba complexes containing both beta-diketonates and N-methyl-pyrrolidone were synthesized and characterized. TGA experiments indicated these complexes are volatile, they can be employed as precursors for ALD strontium titanate (STO) or barium strontium titanate films (BST) films in semiconductor fabrication.
US08247615B2
The present invention is concerned with a process to convert xanthophyll esters derived from Capsicum sources to their free (non-esterified) forms. The present invention is concerned with a process for obtaining Capsicum derived xanthophylls that meet the finished product needs for purity, yield, ease of use, industrial compatibility and cost that are required to make product suitable for the nutritional supplement, food and beverage industries. The present invention is concerned with a process which yields from 60 to 80%, of xanthophyll materials and nearly quantitative recovery of all input xanthophylls, which xanthophylls are of high purity. The present invention concerns a method to obtain xanthophyll esters present almost exclusively in the trans form when isolated from the natural plant sources. The present invention concerns a process to re-convert cis product back to the more desired trans form.
US08247610B2
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, Y, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
US08247608B2
The invention relates to novel compounds of formula (I): H2N—CH(R1)—CH2—S—S—CH2—CH(R2)—CONH—R5, wherein R1 is a hydrocarbon chain, phenyl or benzyl radical, methylene radical substituted by a 5 or 6 atom heterocycle; R2 is a phenyl or benzyl radical, a 5 or 6 atom aromatic heterocycle, methylene group substituted by a 5 or 6 atom heterocycle; R5 is a CH(R3)—COOR4 radical, wherein R3 is hydrogen, an OH or OR group, a saturated hydrocarbon group, a phenyl or benzyl radical and OR4 is hydrophile ester, or 5 or 6 membered heterocycle comprising several heteroatoms selected from a group consisting of nitrogen, sulphur and oxygen, with at least two nitrogene atoms, wherein said heterocycle is substitutable by an alkyl C1-C6, phenyl or benzyl radical. The use of the inventive compounds in the form of drugs, a pharmaceutical composition comprising said compounds, a pharmaceutically acceptable excipient, the use in conjunction of at least one type of cannabinoid derivative for potentiating the analgesic and antidepressant effect of the novel compounds of formula (I) and/or morphine or the derivatives thereof are also disclosed.
US08247607B2
Process for carbonylating an alcohol or reactive derivative thereof, by (a) feeding one or more feed streams to a reaction zone, at least one feed stream containing an alcohol or reactive derivative thereof, and at least one feed stream contains CO, (b) maintaining in the reaction zone a temperature and pressure sufficient to allow an exothermic carbonylation reaction to occur to produce a carboxylic acid or carboxylic acid anhydride, (c) removing one or more product streams containing carboxylic acid or carboxylic acid anhydride from the reaction zone, and (d) transferring heat contained in one or more product streams to a first heat-exchange stream. Heat is transferred from a second heat-exchange stream to a feed stream of step (a) before the feed stream is fed to the reaction zone, and the temperature of the second heat-exchange stream before heat transfer is lower than that of the one or more product streams.
US08247605B2
A method of replacing a first dispersion medium in a starting slurry composed of the first dispersion medium and isophthalic acid crystals with a second dispersion medium. The starting slurry is tangentially fed to a vertically extending cylindrical portion of a cyclone-shaped nozzle disposed at an upper portion of a replacement tank of a dispersion medium replacement apparatus, from a tangential direction of the cylindrical portion. The fed starting slurry moves circularly along an inner wall of the cylindrical portion. The slurry circularly moving is then discharged from an opening which is disposed at a vertically lower end of the cylindrical portion and dispersed in a second dispersion medium which is fed from a lower portion of the replacement tank. The replaced slurry composed of isophthalic acid crystals and the second dispersion medium is mainly discharged from the lower portion of the replacement tank, and the first dispersion medium is mainly withdrawn from the upper portion of the replacement tank.
US08247589B2
The invention provides an organic silicon phosphate and fabrication method thereof. The organic silicon phosphate has formula (I): wherein R1 and R2 are the same or different and represent C1-C5 alkyl; R3 and R4 are the same or different and represent hydrogen, C1-C5 alkyl; R5 is aryl or C1-C5 alkyl; Y is a linking bond containing —CH2—, —C(CH3)2—, —S—, —SO2—, —O—, —CO—, or —N═N—; m is an integer from 0 to 4; n is 0 or 1 and k is an integer from 0 to 9.
US08247588B2
Catalyst compositions for the polymerization of olefins having improved flowability properties are provided.
US08247586B2
Multi-metal phosphonates are generally provided. The multi-metal phosphonate can generally have the composition: AB(RPO3)3, where A is Mg2+, Ca2+, Sr2+, Ba2+, Pb2+, La3+, or combinations thereof; B is Ti4+, Zr4+, Al3−, or combinations thereof; and R is an organic group (e.g., aryl group, an alkyl group, an alkenyl group, etc.). The multi-metal phosphonate can be combined with a polymeric material to form a polymeric film. Methods of making the multi-metal phosphonate by combining and reacting a metal oxide and an organophosphonic acid are also provided.
US08247584B2
The present invention is directed to processes for preparing oil compositions having a high concentration of poly-unsaturated fatty acids and oil compositions having a low concentration of α-linolenic acid. In addition, the present invention is directed to processes for preparing oil compositions having advantageous stability characteristics.
US08247582B2
Disclosed are compositions and methods for the production of mono-esters and di-esters from the reaction of HMF and a reactant selected from a diacid or a diacid derivative; typical reactants are PAN, phthaloyl dichloride, dimethyl phthalate, maleic acid, and maleic anhydride or mono-esters that can be prepared from HMF and MAN.
US08247571B2
Pegylated pyridinium and thiazolium compounds and methods of their use in medicine, research, industry, agriculture and recreational activities are disclosed. The present invention also provides methods of controlling microbial growth and infection. Additionally, the present invention provides methods of controlling microbial infestations relating to industrial and agricultural uses. The present invention can also be used to control insects.
US08247569B2
A compound has a strong analgesic action against both nociceptive pain and neuropathic pain and has less side effects, and is medically useful. The compound includes cyclohexane derivatives represented by the following compound, or pharmaceutically acceptable salts thereof or prodrugs thereof.
US08247565B2
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
US08247563B2
The present invention provides novel indanone derivatives which can be advantageously used for treating and/or preventing of a medical condition for which inhibition of a cholinesterase is desired.
US08247558B2
The present invention provides a process for the preparation of clopidogrel and its pharmaceutically acceptable salts thereof comprises the resolving racemic methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate by the salt formation of methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate with excess levorotatory camphor-10-sulfonic acid to get a maximum yield of camphor sulphonate salt of methyl S-(+)-alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl) (2-chlorophenyl)-acetate and transforming the camphor sulphonate salt to clopidogrel or its pharmaceutically acceptable salts thereof.
US08247556B2
The invention encompasses a method for preparing 6-susbtituted-7-aza-indoles.
US08247551B2
A fluorophore that forms a complex with Pb ions is disclosed. The fluorophore/lead complex fluoresces with an intensity greater than complexes formed by the fluorophore with other metals. The fluorophore may be used as a sensor/detector for lead ions in various samples. Methods for detecting and calculating the concentration of lead ions in samples are also disclosed.
US08247549B2
The present invention discloses a novel method for preparing and purifying 4-(6-Amino-purin-9-yl)-2(S)-hydroxy-butyric acid methyl ester. The preparation started from cheap and easily available L-malic acid, which was transformed to intermediate I after simultaneous protection of the groups of 1-carboxyl and 2-hydroxyl. The intermediate I was selectively reduced to intermediate alcohol II, whose hydroxyl group was further transformed to an easily leaving group to afford intermediate III. The intermediate III was nucleophilically substituted with adenine to afford intermediate IV. The intermediate IV was deprotected and methyl-esterified simultaneously in methanol in the presence of an acid or a base to afford crude 4-(6-Amino-purin-9-yl)-2(S)-hydroxy-butyric acid methyl ester, which was purified by recrystallization to afford the purified product. Comparing with the prior preparation methods, the present method has advantages in low cost, mild conditions, high retention of the chiral center during the reaction, high productivity, great improvement in the quality and yield of the product and great decrease in cost, and thus is suitable for the production on a large scale.
US08247547B2
Processes for the preparation of Caralluma extract which includes shade-drying of Caralluma plant material; ii) treating the dried Caralluma plant material by at least one operation selected from a group consisting of sorting, cleaning and sizing to obtain Caralluma plant material meant for extraction or any combination thereof; iii) extracting the Caralluma plant material with a first solvent for at least two initial iterations followed by at least two subsequent iterations with a second solvent at controlled temperature to obtain a diluted extract; iv) removing the solvent from the diluted extract by distillation at a temperature below about 40° C. to obtain a concentrate; v) chilling the concentrate at a temperature of about 6 to about 10° C. for a period of about 7 to about 8 hours to obtain a chilled concentrate; vi) filtering the chilled concentrate to obtain a filtrate; vii) concentrating the filtrate at a temperature below about 60° C. to obtain a viscous liquid; viii) spray-drying the concentrated viscous liquid to obtain a powder; and ix) pulverizing and sifting the dried powder to obtain a Caralluma extract provided. Such extracts may be included in medicinal formulations used for the prevention and treatment of obesity and obesity-related conditions for subjects in need thereof.
US08247546B2
Acid polysaccharides characterized by the concomitant presence of partial esters with non-polysaccharide carboxylic acids and esters between the acid groups of the initial polysaccharide and the alcohol groups of the repetitive units, with the formation of crosslinking among the polysaccharide chains.
US08247544B2
A DNAzyme is disclosed, which comprises: (i) a catalytic domain with a nucleotide sequence GGCTAGCTACAACGA or a modified sequence of comparable biological effect, which cleaves T-bet mRNA at every purine-pyrimidine binding site to which it is bound; (ii) a right substrate binding domain which is contiguous with the 3′-end of the catalytic domain; and (iii) a left substrate binding domain which is contiguous with the 5′-end of the catalytic domain, whereby the two substrate binding domains are respectively complementary to two regions of the T-bet mRNA so that they hybridize with the mRNA; are active in vivo; and contain the sequences td 69 GGCAATGAA GGC TAGCTACAACGA TGGGTTTCT or td70 TCACGGCAA GGCTAGCTACAACGA GAACTGGGT.
US08247543B2
The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a microRNA shown in SEQ ID NOs: 1-94; 281-374; 467-481; 497-522; or 549, except that up to thirty percent of the bases may be wobble bases, and up to 10% of the contiguous bases may be non-complementary. The invention further relates to modified single stranded microRNA molecules, isolated single stranded anti-microRNA molecules and isolated microRNP molecules. In another embodiment, the invention relates to a method for inhibiting microRNP activity in a cell.
US08247535B2
Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided, particularly polypeptide variants of SEQ ID NO:2 and 4. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:7-28, or the nucleotide sequence set forth in SEQ ID NO:29 or 30.
US08247532B2
This invention relates to processes and intermediates for the preparation of salts of deuterated, enantiomericallv enriched alpha-amino beta-hydroxy acids of Formula 1 wherein the variables R1,R′1 and R′2 are defined herein, and wherein the process may comprise the steps of forming a salt of a compound of Formula 1, and crystallizing said salt to give a compound of greater than 55% enantiomeric excess.
US08247527B2
A fine agglomerates mixture formed from pyrolysis of recyclable polymeric material such as scrap tires, polymeric automotive components, used rubber materials, and plastic containers. The mixture contains a carbon content ranged between about 80% to about 95% by weight of the fine agglomerates mixture. The fine agglomerates mixture has agglomerate particles averaging less than or equal to 35 nm. The fine agglomerates mixture also has a nitrogen surface area greater than or equal to 73 m2/g and includes an inorganic functional filler in a range between about 5% to about 20% weight of the fine agglomerates mixture.
US08247526B2
Polyalkylene ether glycol or copolymer thereof are prepared by contacting at least one alkanediol with a alkanediol containing cyclic sulfate.
US08247519B1
The invention is directed to shaped articles fabricated from polyamides comprising fluoroether functionalized aromatic moieties. Particular polyamides include nylon 6, 6 and nylon 6 copolyamides that comprise fluoroether functionalized aromatic amide repeat units. The shaped articles hereof are characterized by reduced surface tension and are useful for imparting soil resistant films, molded parts, fibers, fabrics, and carpets.
US08247508B2
An isobutylene-based polymer comprising a structural unit represented by the following formula (1): and a structural unit represented by the following formula (2): wherein X represents a divalent group; Y represents a substituted or unsubstituted alicyclic group having an unsaturated bond in the ring; and n represents 0 or 1.
US08247505B2
The present invention provides a process for preparing a fluorine-containing elastomer in a high productivity comparable to that of non-iodine transfer polymerization process by carrying out an iodine transfer polymerization at high pressure. The present invention also provides a fluorine-containing elastomer prepared by this process, and fluorine-containing molded articles. The process is a batch copolymerization process conducted under conditions that the reduced temperature of the critical constant is at least 0.95 and the reduced pressure of the critical constant is at least 0.80 wherein the reduced temperature and the reduced pressure are calculated using the Peng-Robinson formula from the critical temperature, the critical pressure and the composition ratio of each of the monomers in the gaseous phase in a reaction vessel, in which ethylenically unsaturated compounds containing at least one fluoroolefine are copolymerized in the presence of a compound having the formula: Rf1·Ix wherein Rf1 is a saturated or unsaturated fluorohydrocarbon or chlorofluorohydrocarbon group having 1 to 16 carbon atoms, and x is the number of bonds of Rf1 and an integer of 1 to 4.
US08247500B2
A polymeric resin comprising guanidine groups having at least one C4-C22 tertiary alkyl substituent.
US08247497B2
The invention relates to formulated compositions which can be easily formed into bottle caps, without the need for a liner, while still maintaining pressure requirements, such as for carbonated beverages. The compositions may include an ethylene polymer having a density in the range of from about 0.947 to 0.962 g/cm3, a melt index of from about 1 to about 10 g/10 min., and another ethylene polymer having a density in the range of from about 0.912 to 0.932 g/cm3, a melt index of from about 0.25 to about 6 g/10 min., wherein the two ethylene polymers have a density difference of equal to or greater than 0.03 g/cm3. In other cases, the composition may include a single component resin with a density in the 0.935-0.955 g/cm3 range with a melt index in the range of 0.3-1.2 g/10 minutes, and wherein the resin comprises a polyethylene polymer.
US08247496B2
The invention provides for processes to produce elastomeric compositions, the processes including contacting at least one elastomer with a processing aid, wherein the processing aid comprises at least one functionalized polymer having at least one halogen group. The invention also provides for articles such as innerliners for tires produced from the aforementioned elastomeric compositions.
US08247495B2
Elastomeric polymer blends and processes for their production are described. Specifically, the polymer blends comprise a first polymer and a second polymer, where the first polymer comprises from about 70 wt % to about 90 wt % units derived from propylene and from about 10 wt % to about 30 wt % units derived from ethylene and/or a C4-C10 alpha-olefin, and the second polymer comprises from about 88 wt % to about 98 wt % units derived from propylene and from about 2 wt % to about 12 wt % units derived from ethylene and/or a C4-C10 alpha-olefin. The elastomeric polymer blends are further characterized by having two or more of the following properties: an overall propylene content of between about 75 wt % and about 90 wt %, a melting point between about 110° C. and about 145° C., a Vicat softening point greater than about 45° C., a tensile stress at 300% strain of less than about 500 psi (3447 kPa), as determined by a stress strain test according to ASTM D412, or an average maximum force for pellet separation of less than about 10 N in an accelerated storage stability test. The polymer blends are produced in a dual reactor process, in which the first polymer and the second polymer are prepared using differing catalyst systems.
US08247482B2
The invention relates to a composition comprising at least one (poly)isocyanate and at least one surfactant comprising an amino acid and a mixture of compounds of formulae (I) and (II) wherein i and j independently represent 0 or 1; and R1 et R2 are identical or different and independently represent a hydrocarbonated chain. Said mixture of compounds of formulae (I) and (II) is characterized in that the molar ratio between compound (II) and compound (I) is higher than 1.
US08247481B2
A photosensitive insulating resin composition includes a block copolymer, a crosslinking agent, a photosensitive compound, and a solvent. The block copolymer includes a first structural unit shown by a following formula (1) and a second structural unit shown by a following formula (2), wherein R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and R2 represents an alkyl group having 1 to 4 carbon atoms.
US08247471B2
To provide a dental adhesive composition which does not decrease preservation stability when reacting with acidity for acquiring dental adhesive property, even though using a filler having X-ray imaging property, and does not need the conventional mixing and kneading of two or more components, the dental adhesive composition includes (a) a (meth)acrylate compound having an acid group, and (b) aluminosilicate glass powder containing Sr and/or Ba and/or Ca, and the dental adhesive composition further includes a filler and (c) a photopolymerization catalyst, where the filler does not substantially make a neutralization reaction with the (meth)acrylate compound having an acid group as the (a) component because a filler content is 15% by weight or less in terms of oxide of Al2O3, and those coexist is one.
US08247470B2
To provide a polymerizable composition having more excellent preservation stability of pastes than a conventional composition using a combination of a copper compound, cumene hydroperoxide, and N-acetylthiourea, and having a polymerization curing time which does not change with time, that is, does not delay or quicken from a time set for a product even though the composition is stored, the polymerizable composition includes a first paste and a second paste, wherein the first paste includes a polymer of α-β unsaturated monocarboxylic acid or α-β unsaturated dicarboxylic acid, water, and a hydroperoxide as a peroxide, and the second paste includes a (meth)acrylate compound not having an acid group, fluoroaluminosilicate glass powder, a thiourea derivative as a reducing material, and a vanadium compound as a polumerization accelerator.
US08247468B2
The present invention provides a composition for hard coat capable of forming a hard coat layer having the improved anti-staining property, anti-staining durability, scratch resistance, abrasion resistance, antistatic property and the like. A composition for hard coat comprising: an active energy ray-curable silicone-acrylic copolymer (A); an active energy ray-curable polyfunctional compound (B); and an electrically conductive material (C), wherein the active energy ray-curable silicone-acrylic copolymer (A) contains: a polysiloxane block (a-1), an acrylic block (a-2) containing an active energy ray-curable double bond group, and a fluoroalkyl group-containing acrylic block (a-3).
US08247456B2
The present invention relates to the use of compositions comprising trans-clomiphene for treating men with hypogonadism. The invention is also directed to methods for treating males with hypogonadism and disorders related thereto, including reduction of muscle mass, limitation of body performance capacity, reduction of bone density, reduction of libido, reduction of potency, reduction of benign prostatic hyperplasia and infertility.
US08247449B2
The present invention provides methods of treating an inflammatory disorder, or a disorder having an inflammatory component, in a mammalian subject in need of such treatment by administering to said subject an effective amount of a composition in unit dosage form for delivery of a daily dose of said composition, said composition consisting essentially of: (i) an effective amount of γ-linolenic acid (GLA) for increasing dihomogammalinolenic acid (DGLA) levels in the inflammatory cells of said mammalian subject, thereby inhibiting the metabolism of arachidonic acid; (ii) an effective amount of a Δ5 desaturase inhibitor for inhibiting accumulation of arachidonic acid in the serum of said mammalian subject; and, optionally, (iii) an effective amount of a competitive inhibitor of arachidonic acid metabolism. Preferred formulations may be in the form of a good tasting, preferably milk or fruit based drink, or a dried powder. The compositions reduce inflammation and inhibit the increase in serum arachidonic acid associated with gamma-linolenic acid.
US08247445B2
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.
US08247441B2
The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.
US08247440B2
The present disclosure relates to pharmaceutical compositions comprising omeprazole, lansoprazole and at least one buffering agent.
US08247439B2
The present invention relates to novel jasmonate derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as chemotherapeutic agents for prevention and treatment of cancers.
US08247432B2
The present invention is concerned with novel compounds of formula (I) which are inhibitors of a membrane tripeptidyl peptidase responsible for the inactivation of endogenous neuropeptides such as cholecystokinis (CCKs).
US08247421B2
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
US08247415B2
The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
US08247414B2
The present invention is directed to novel pyridizinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition.
US08247412B2
The present invention provides compounds of formula (I): in which R1, R′1, R2, R′2, R3, Y and G have the meanings given in the description, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.
US08247408B2
The invention is directed to Compounds of Formula I and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.
US08247406B2
The present invention provides a photosensitizing composition for treatment of MRSA comprising a photosensitizer and chlorhexidine and a pharmaceutically acceptable carrier. The present invention also provides a method for reducing disease causing microbes comprising: applying the composition comprising a photosensitizer, chlorhexidine at a concentration of more than about 0.01% and less than about 2% v/v, and a pharmaceutically acceptable carrier to a treatment site; and applying light to the treatment site at a wavelength absorbed by the photosensitizer so as to reduce the microbes at the treatment site.
US08247403B2
Compounds represented by the general formula (I): wherein each symbol is as defined in the description [with the proviso that 9-chloro-7-(1,1-dimethylethyl)-2,3,4,5-tetrahydro-1,4-benz-oxazepine and N-[[(5S)-2-oxo-3-(2,3,4,5-tetrahydro-1,4-benz-oxazepin-7-yl)-5-oxazolidinyl]methyl]acetamide are excluded], salts of the same, and prodrugs thereof have selective activation effect on serotonin 5-HT2C receptor and are useful as preventive and therapeutic agents for lower urinary tract diseases, obesity, and/or pelvic organ prolapse.
US08247397B2
Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
US08247395B2
A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.
US08247389B2
The present invention provides a method of treating scleroderma. The method consists in the upregulation of miR-29 by administration of miR-29 or a miR-29 upregulator which elevates circulating and/or intracellular concentrations of miR-29. The invention likewise relates to the use of miR-29 for such a treatment, and the use of miR-29 for the manufacture of a medicament for the treatment of scleroderma.
US08247388B2
The ability of miR-181a to support active signaling between Notch and pre-TCR pathways by coordinately dampening negative regulators of these pathways allows the use of miR-181a as a therapeutic target for T-ALL.
US08247380B2
This invention characterizes the selective apoptotic activity of specially prepared zinc charged alpha 1-acid glycoprotein, alpha 2-HS glycoprotein, and alpha 1-antitrypsin. These proteins cause apoptosis in cancer cells while leaving normal cells intact. In addition, active fragments of zinc charged alpha 1-acid glycoprotein and alpha 2-HS glycoprotein, whether manufactured from the modification of natural alpha 1-acid glycoprotein or alpha 2-HS glycoprotein, recombinantly, or synthetically, selectively induce apoptosis.
US08247372B2
Compounds which are Spiruchostatin analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.
US08247369B2
Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
US08247365B2
A detoxicant solution includes 0.1 to 50 parts by weight of at least one Friedel-Crafts reagent (Lewis acids) (I); 0.5 to 80 parts by weight of one or more of the following specific solvents (II): dimethyl sulfoxide, 1,3-dimethyl-2-imidazolidinone or octamethylcyclotetrasiloxane; and 1 to 80 parts by weight of an alcoholic solvent (III). The term “parts by weight” relates in each case to 100 parts by weight of the complete detoxicant solution.
US08247360B2
The present invention provides a refrigerating machine oil, a compressor oil composition, a hydraulic oil composition, a metalworking oil composition, a heat treating oil composition, a lubricating oil composition for machine tools and a lubricating oil composition which comprise a lubricating oil base oil having % CA of not more than 2, % CP/% CN of not less than 6 and an iodine value of not more than 2.5.
US08247359B2
In one aspect, the present invention provides a water-in-oil emulsion comprising from about 5 to about 40 wt % aqueous phase and from about 95 to about 60 wt % non-aqueous phase, said aqueous phase being dispersed in said non-aqueous phase in the form of droplets having an average droplet size no greater than about 0.1 μm, said emulsion comprising: at least 60 wt % of an oil selected from fuel oils, lubricating oils and mixtures thereof, from about 1 to about 30 wt % of emulsifying agents, and the balance to 100 wt % water, wherein said emulsifying agents include a fatty (C8-C24)-amido-(C1-C6)alkyl betaine, is useful as a fuel, coolant or lubricant. In another aspect the present invention provides one or more stable, clear, water-in-fuel microemulsion-forming surfactants may be used in a liquid fuel or oil which is immiscible with water to: a) scavenge free-water which exists in or is introduced into the liquid fuel or oil thereby to render or retain the liquid fuel or oil in a usable state; and/or b) inhibit the growth of aquatic micro-organisms in the liquid fuel or oil when the fuel or oil becomes contaminated with free-water thereby to retain the liquid fuel or oil in a usable state.
US08247351B2
The present invention concerns boosting the activity of crop protection materials comprising active ingredients from the class of the phenyl-substituted cyclic ketoenols through the addition of ammonium salts and/or phosphonium salts or through the addition of ammonium salts and/or phosphonium salts and penetrants, the corresponding materials, processes for preparing them, and their use in crop protection.
US08247349B2
This invention relates to the use of nitrogen and/or calcium containing fertilizers or salts to improve the performance of abscisic acid (ABA) analogs and ABA derivatives on tomato leaf transpiration inhibition. This invention also relates to the use of ABA analogs or derivates or their salts to reduce the phytotoxicity of foliar applied nitrogen and/or calcium-containing fertilizers or salts.
US08247329B2
A method for forming a semiconductor device includes forming a nanotube region using a thin epitaxial layer formed on the sidewall of a trench in the semiconductor body. The thin epitaxial layer has uniform doping concentration. In another embodiment, a first thin epitaxial layer of the same conductivity type as the semiconductor body is formed on the sidewall of a trench in the semiconductor body and a second thin epitaxial layer of the opposite conductivity type is formed on the first epitaxial layer. The first and second epitaxial layers have uniform doping concentration. The thickness and doping concentrations of the first and second epitaxial layers and the semiconductor body are selected to achieve charge balance. In one embodiment, the semiconductor body is a lightly doped P-type substrate. A vertical trench MOSFET, an IGBT, a Schottky diode and a P-N junction diode can be formed using the same N-Epi/P-Epi nanotube structure.
US08247326B2
The invention is directed to a method of chemically-mechanically polishing a surface of a substrate, comprising contacting a surface of a substrate comprising nickel-phosphorous with a chemical-mechanical polishing composition comprising wet-process silica, an agent that oxidizes nickel-phosphorous, and an aminopolycarboxylic acid, wherein the polishing composition has a pH of about 1 to about 5, and abrading at least a portion of the nickel-phosphorous to polish the substrate.
US08247325B2
Metal nanoplates are grown on n-type and p-type semiconductor wafer substrates through galvanic reactions between substantially pure aqueous metal solutions and the substrates. The morphology of the resulting metal nanoplates that protrude from the substrate can be tuned by controlling the concentration of the metal solution and the reaction time of the solution with the semiconductor wafer. Nanoplate size gradually increases with prolonged growth time and the nanoplate thicknesses increases in a unique stepwise fashion due to polymerization and fusion of adjacent nanoplates. Further, the roughness of the nanoplates can also be controlled. In a particular embodiment, Ag nanoplates are grown on a GaAs substrate through reaction with a solution of AgNO3 with the substrate.
US08247324B2
A method for fabricating a semiconductor device includes forming landing plugs over a substrate, forming a trench by etching the substrate between the landing plugs, forming a buried gate to partially fill the trench, forming a gap-fill layer to gap-fill an upper side of the buried gate, forming protruding portions of the landing plugs, and trimming the protruding portions of the landing plugs.
US08247320B2
The invention relates to a process for producing electrodes for solar cells, the electrode being configured as an electrically conductive layer on a substrate for solar cells, in which, in a first step, a dispersion comprising electrically conductive particles is transferred from a carrier to the substrate by irradiating the dispersion with a laser and, in a second step, the dispersion transferred to the substrate is dried and/or hardened to form the electrically conductive layer.
US08247312B2
A method of printing an ink on a wafer surface configured with a set of non-rounded peaks and a set of non-rounded valleys is disclosed. The method includes exposing the wafer including at least some non-rounded peaks and at least some of the non-rounded valleys in a region to an etchant. The method further includes depositing the ink on the region, wherein a set of rounded peaks and a set of rounded valleys are formed.
US08247307B2
A plurality of rectangular single crystal semiconductor substrates are prepared. Each of the single crystal semiconductor substrates is doped with hydrogen ions and a damaged region is formed at a desired depth, and a bonding layer is formed on a surface thereof. The plurality of single crystal substrates with the damaged regions formed therein and the bonding layers formed thereover are arranged on a tray. Depression portions for holding the single crystal semiconductor substrates are formed in the tray. With the single crystal semiconductor substrates arranged on the tray, the plurality of single crystal semiconductor substrates with the damaged regions formed therein and the bonding layers formed thereover are bonded to a base substrate. By performing heat treatment and dividing the single crystal semiconductor substrates along the damaged regions, the plurality of single crystal semiconductor layers that are sliced are formed over the base substrate.
US08247306B2
A solid-state image pickup device includes: a silicon layer; a pixel portion formed in the silicon layer for processing and outputting signal charges obtained by carrying out photoelectric conversion for incident lights; an alignment mark formed in a periphery of the pixel portion and in the silicon layer; and a contact portion through which a first electrode within a wiring layer formed on a first surface of the silicon layer, and a second electrode formed on a second surface opposite to the first surface of the silicon layer through an insulating film are connected, wherein the alignment mark and the contact portion are formed from conductive layers made of the same conductive material and formed within respective holes each extending completely through the silicon layer through respective insulating layers made of the same material.
US08247302B2
A method of fabricating a substrate includes forming spaced first features and spaced second features over a substrate. The first and second features alternate with one another and are spaced relative one another. Width of the spaced second features is laterally trimmed to a greater degree than any lateral trimming of width of the spaced first features while laterally trimming width of the spaced second features. After laterally trimming of the second features, spacers are formed on sidewalls of the spaced first features and on sidewalls of the spaced second features. The spacers are of some different composition from that of the spaced first features and from that of the spaced second features. After forming the spacers, the spaced first features and the spaced second features are removed from the substrate. The substrate is processed through a mask pattern comprising the spacers. Other embodiments are disclosed.
US08247301B2
A substrate having, on a base material, a barrier film for preventing copper diffusion containing one or more metal elements selected from tungsten, molybdenum and niobium, a metal element having a catalytic function in electroless plating such as ruthenium, rhodium, and iridium, and nitrogen contained in the form of a nitride of the aforementioned one or more metal elements selected from tungsten, molybdenum and niobium. The barrier film for preventing copper diffusion is manufactured by sputtering in a nitrogen atmosphere using a target containing one or more metal elements selected from tungsten, molybdenum and niobium and the aforementioned metal element having a catalytic function in electroless plating.
US08247298B2
Disclosed is a method of manufacturing a semiconductor device comprising: forming a first layer on a sidewall of a trench formed on a main surface of a semiconductor substrate, filling up the trench with a protective film, etching back the protective film by a dry etching method so that a height of a surface of the protective film is lower than an opening of the trench and removing the first layer exposed by the etching-back.
US08247295B2
A DMOS type semiconductor device and a method for manufacturing the same are provided. An isolation oxide layer with an ion implantation opening is formed on a semiconductor. A gate oxide film is formed on the semiconductor within the ion implantation opening. A gate is formed on the isolation oxide layer and the gate oxide film. A body layer diffusively formed in the semiconductor by implanting ions of an impurity element having a first conduction type from the ion implantation opening. A regulation layer which is shallower than the body layer is diffusively formed in the body layer by implanting ions of an impurity element having a second conduction type opposite to the first conduction type from the ion implantation opening. A source layer is diffusively formed in the regulation layer by implanting ions of an impurity element having the second conduction type from the ion implantation opening. The regulation layer is formed so as to horizontally extend beyond a region in which a gate bird's beak occurs from an end of the gate toward underlying layers of the gate.
US08247287B2
In one embodiment, a method comprises forming an epitaxial layer over a substrate of an opposite conductivity type, the epitaxial layer being separated by a buffer layer having a doping concentration that is substantially constant in a vertical direction down to the buffer layer. A pair of spaced-apart trenches is formed in the epitaxial layer from a top surface of the epitaxial layer down at least into the buffer layer. A dielectric material is formed in the trenches over the first and second sidewall portions. Source/collector and body regions of are formed at the top of the epitaxial layer, the body region separating the source/collector region of the pillar from a drift region of the epitaxial layer that extends from the body region to the buffer layer. An insulated gate member is then formed in each of the trenches adjacent to and insulated from the body region.
US08247286B2
One embodiment of inventive concepts exemplarily described herein may be generally characterized as a semiconductor device including an isolation region within a substrate. The isolation region may define an active region. The active region may include an edge portion that is adjacent to an interface of the isolation region and the active region and a center region that is surrounded by the edge portion. The semiconductor device may further include a gate electrode on the active region and the isolation region. The gate electrode may include a center gate portion overlapping a center portion of the active region, an edge gate portion overlapping the edge portion of the active region, and a first impurity region of a first conductivity type within the center gate portion and outside the edge portion. The semiconductor device may further include a gate insulating layer disposed between the active region and the gate electrode.
US08247284B2
A method for manufacturing a semiconductor device includes the steps of (a) forming a gate electrode on a silicon substrate, through a gate insulating film; (b) forming a lamination of an insulating film and a sacrificial film having different etching characteristics on the silicon substrate, covering the gate electrode, and anisotropically etching the lamination to form side wall spacers on side walls of the gate electrode and the gate insulating film; (c) implanting impurities into the silicon substrate on both sides of the side wall spacers; (d) etching the silicon substrate and the sacrificial film to form recesses in the silicon substrate, and to change a cross sectional shape of each of the side wall spacers to approximately an L-shape; (e) epitaxially growing Si—Ge-containing crystal in the recesses; and (f) depositing an insulating film containing stress, covering the side wall spacers.
US08247279B2
A semiconductor device according to one embodiment includes: a first transistor comprising a first gate electrode formed on a semiconductor substrate via a first gate insulating film, a first channel region formed in the substrate under the first film, and first epitaxial crystal layers formed on both sides of the first channel region in the substrate, the first layers comprising a first crystal; and a second transistor comprising a second gate electrode formed on the substrate via a second gate insulating film, a second channel region formed in the substrate under the second film, second epitaxial crystal layers formed on both sides of the second channel region in the substrate, and third epitaxial crystal layers formed on the second layers, the second layers comprising a second crystal, the third layers comprising the first crystal, the second transistor having a conductivity type different from that of the first transistor.
US08247277B2
A manufacturing method of a thin film transistor is provided. An insulating pattern layer having at least one protrusion is formed on a substrate. At least one spacer and a plurality of amorphous semiconductor patterns separated from each other are formed on the insulating pattern layer. The spacer is formed at one side of the protrusion and connected between the amorphous semiconductor patterns. The spacer and the amorphous semiconductor patterns are crystallized. The protrusion and the insulating pattern layer below the spacer are removed so that a beam structure having a plurality of corners is formed and suspended over the substrate. A carrier tunneling layer, a carrier trapping layer and a carrier blocking layer are sequentially formed to compliantly wrap the corners of the beam structure. Hereafter, a gate is formed on the substrate to cover the beam structure and wrap the carrier blocking layer.
US08247271B2
A structure fabrication method. First, an integrated circuit including N chip electric pads is provided electrically connected to a plurality of devices on the integrated circuit. Then, an interposing shield having a top side and a bottom side and having N electric conductors in the interposing shield is provided being exposed to a surrounding ambient at the top side but not at the bottom side. Next, the integrated circuit is bonded to the top side of the interposing shield such that the N chip electric pads are in electrical contact with the N electric conductors. Next, the bottom side of the interposing shield is polished so as to expose the N electric conductors to the surrounding ambient at the bottom side of the interposing shield. Then, N solder bumps are formed on the polished bottom side of the interposing shield and in electrical contact with the N electric conductors.
US08247267B2
A wafer level integrated circuit assembly method is conducted as follows. First, a mother device wafer with plural first posts is provided. The first posts are used for electrical connection and are made of copper according to an embodiment. Solder is sequentially formed on the first posts. The solder is preferably pre-formed on a wafer, and the locations of the solder correspond to the first posts of the mother device wafer. Consequently, the solder can be formed on or adhered to the first posts by placing the wafer having pre-formed solder onto the first posts. Plural dies having plural second posts corresponding to the first posts are placed onto the mother device wafer. Then, the solder is reflowed to bond the first and second posts, and the mother device wafer is diced.
US08247266B2
A thin film transistor (TFT) using an oxide semiconductor layer as an active layer, a method of manufacturing the TFT, and a flat panel display (FPD) including the TFT are taught. The TFT includes a gate electrode formed on a substrate, an oxide semiconductor layer electrically insulated from the gate electrode by a gate insulating layer, and the oxide semiconductor layer including a channel region, a source region, and a drain region, and a source electrode and a drain electrode respectively electrically contacting the source region and the drain region. The oxide semiconductor layer is formed of an InZnO or IZO layer (indium zinc oxide layer) including Zr. The carrier density of the IZO layer is controlled to be 1×1013 to 1×1018 #cm−3 by controlling an amount of Zr.
US08247251B2
A method of fabricating a light-emitting element, in which less stress is applied to the light-emitting element, includes: forming element isolation patterns on a substrate; forming a buffer layer on an entire surface of the substrate to directly contact the surface of the substrate and the element isolation patterns and forming light-emitting structure layers on the buffer layer; forming element isolation trenches, which overlap at least part of the element isolation patterns, respectively, buffer layer patterns and light-emitting structures which are separated from each other by the element isolation trenches, respectively, by etching the buffer layer and the light-emitting structure layers; injecting a lift-off solution into the element isolation trenches to remove the element isolation patterns; and removing the substrate.
US08247248B2
A method for forming a layer of phosphor material on an LED encapsulant structure includes forming a layer of a phosphor material on a first surface, disposing the first surface to cause the phosphor material to be in contact with a surface of the LED encapsulant structure, applying a pressure between the first surface and the surface of the LED encapsulant structure, and causing the layer of the phosphor material to be attached to the LED encapsulant structure.
US08247243B2
Methods and devices for solar cell interconnection are provided. In one embodiment, the method includes physically alloying the ink metal to the underlying foil (hence excellent adhesion and conductivity with no pre-treatment), and by fusing the solid particles in the ink on the surface (eliminating any organic components) so that the surface is ideally suited for good conductivity and adhesion to an overlayer of finger ink, which is expected to be another adhesive. In some embodiments, contact resistance of conductive adhesives are known to be much lower on gold or silver than on any other metals.
US08247241B2
According to an aspect of the invention, there is provided a method for detecting a target compound including: injecting a test liquid containing a target compound into a colloid solution of magnetic nano-particles having an average particle diameter of 50 nm or less to allow the target compound to bind to the magnetic nano-particles, thereby forming bound magnetic nano-particles having a diameter of 100 nm or more; and bringing a dispersion liquid containing the bound magnetic nano-particles in proximity to a magnetic sensor including at least a magnetoresistive (MR) element and a permanent magnet while measuring the change in magnetic resistance to selectively detect the bound magnetic nano-particles, thereby indirectly detecting the target compound.
US08247236B2
Methods of evaluating molecular isomers of branched-chain amino acids are featured. The methods can include: derivatizing one or more molecular isomers of branched-chain amino acids in a sample comprising a branched-chain amino acid labeled with one or more heavy atoms as a first standard; adding, to the sample, after derivatization, a nonderivatized or derivatized branched chain amino acid that is labeled with one or more heavy atoms, as a second standard; evaluating the sample using tandem mass spectrometry; and detecting peaks indicative of derivatized and nonderivatized forms of one or more branched-chain amino acids in the sample.
US08247235B2
The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention.
US08247222B2
This invention relates to a method and apparatus for processing cell cultures. The apparatus comprises a micro-chamber comprising no more than one absorption layer and at least one gel layer, in this order, laminated on a transparent base plate having no conspicuous absorbency in visible and infrared regions, and at least one light source, the absorption layer having absorbency in visible and infrared regions, and the gel-like material being a substance which has a gel dissolution temperature of 100 degree C. or less, solates when heated and is in a gel state at room temperature and has absorbency for a specific wave length of visible and infrared regions, and the light source having a monochromatic light in the specific wave length, wherein the light source is disposed such that it irradiates on the absorption layer and/or the gel layer, with the exception that when no absorption layer is provided, at least two layers each composed of a gel-like material are laminated on the transparent base plate.
US08247216B2
Apparatus, systems and methods for use in analyzing discrete reactions at ultra high multiplex with reduced optical noise, and increased system flexibility. Apparatus include substrates having integrated optical components that increase multiplex capability by one or more of increasing density of reaction regions, improving transmission of light to or collection of light from discrete reactions regions. Integrated optical components include reflective optical elements which re-direct illumination light and light emitted from the discrete regions to more efficiently collect emitted light. Particularly preferred applications include single molecule reaction analysis, such as polymerase mediated template dependent nucleic acid synthesis and sequence determination.
US08247215B2
Provided is a cell chip for exposing to a portion of each of cells microdroplets dispensed with an inkjet printer or the like in a screening test of the effect of a substance on cells by using an apparatus for introducing the substance into cells including: a cell-immobilizing support including a substrate having through-holes penetrating from one side to the other side of the substrate and including cells immobilized in the through-holes so as to block up the through-holes; a liquid phase region present in contact with one side of the support and including a medium of the cells; and a mechanism present so as to face the other side of the support and imparting a microdroplet to a portion of each of the cells exposed in the openings on the other side.
US08247210B2
Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided.
US08247195B2
Methods for expressing recombinant polypeptides in host cells and host cells for polypeptide expression are provided.
US08247177B2
The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which permit the sequential determination of nucleotide sequences in two distinct and separate regions on complementary strands of the double-stranded polynucleotide template. The two regions for sequence determination may or may not be complementary to each other.
US08247169B2
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for DGAT2.
US08247168B2
The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins.
US08247167B2
Isolated, latently infected T cell lines are provided that can be utilized in high throughput screening to discover compounds capable of activating HIV-I. The T cell lines harbor a latent HIV-I derived vector pro virus, which upon activation expresses a marker for late viral gene expression due to the insertion of the marker gene in the position of HIV-I envelope.
US08247155B2
The present invention provides a process for producing a colored toner comprising the steps of: providing a polymer composition comprising at least one polymer wherein the at least one polymer has a softening temperature from about 30° C. to about 160° C.; and a colorant; forming an aqueous mineral suspension of at least one multivalent metal phosphate by contacting a water-soluble salt of the multivalent metal with an aqueous solution comprising: a water-soluble phosphate salt; and at least one crystal growth inhibitor which controls the growth of the at least one multivalent metal phosphate, wherein the pH of the aqueous mineral suspension is from 5.5 to 14; and forming a dispersion of the polymer composition by adding the polymer composition to the aqueous mineral suspension under agitation to form a solid portion comprising dispersed particles of the polymer composition, wherein the temperature of the aqueous mineral suspension during the dispersing step is at least about 70° C.
US08247147B2
A toner including toner particles containing at least a binder resin and a colorant. The binder resin is a vinyl-based resin. The toner contains a THF insoluble matter in a quantity of 0.0 mass % or more to less than 16.0 mass %. The toner has a main peak in a molecular weight domain Dr1 ranging from 5,000 to 80,000 in measurement of THF soluble matter of the toner with a gel permeation chromatogram (GPC)-differential refractive index detector (RI), and the toner has a main peak in a molecular weight domain Dm1 ranging from 10,000 to 120,000 and at least one peak in a molecular weight domain Dm2 ranging from 300,000 to 7,000,000 in the GPC-RI measurement in measurement with a GPC-multi-angle laser light scattering detector (MALLS).
US08247143B2
A photoreceptor including an electroconductive substrate, a photosensitive layer located overlying the electroconductive substrate, and a surface layer located overlying the photosensitive layer, wherein the surface layer is a cross linked surface layer comprising filler particulates on which linear scar is formed along the circumference direction, and the filler particulates form concave portions on a groove formed by the linear scar, and wherein the ten point average roughness Rz along the direction of the rotation axis of the photoreceptor measured on the circumference surface thereof is from 0.17 to 2.00 μm and the average distance Sm of concavities and convexities along the direction of the rotation axis of the photoreceptor measured on the circumference surface thereof is from 20 to 500 μm, and the ten point average roughness Rz along the circumference direction of the photoreceptor measured on the circumference surface thereof is from 0.13 to 0.50 μm and the average distance Sm of concavities and convexities along the circumference direction of the photoreceptor measured on the circumference surface thereof is from 10 to 40 μm.
US08247142B1
A fluorinated structured organic film comprising a plurality of segments and a plurality of linkers arranged as a covalent organic framework, wherein the fluorine in the structured organic film may be distributed in a patterned uniform manner.
US08247133B2
A fuel cell includes a separator having circular disks. On a surface of each of the circular disks, a fuel gas channel is provided for supplying a fuel gas to an anode. The fuel gas channel includes ring shaped grooves and ridges provided alternately, wherein the width of the ring shaped grooves gradually increases outwardly from a fuel gas inlet.
US08247131B2
A fuel cell stack includes a load receiver provided at an outer end of a fuel cell unit, a guide receiver provided in a box, and a pressure receiver provided in at least one corner in the box. The guide receiver abuts against the load receiver for receiving the external load. The pressure receiver protrudes toward the fuel cell unit. The pressure receiver abuts against a corner of the fuel cell unit for receiving the load. The pressure receiver has a resin receiver, and the resin receiver abuts against a curved portion of the fuel cell unit for supporting the fuel cell unit.
US08247129B2
A fuel cell provided with a reforming catalyst is located in a high-temperature portion on the anode side to cool the high-temperature portion by means of heat absorption of reforming reaction, or a combustion catalyst is provided in a low-temperature portion on the anode side to heat the low-temperature portion by means of heat generation of combustion reaction, or both of the catalysts are provided, by which the occurrence of variations in temperature in a cell reaction region of anode is prevented.
US08247128B2
A fuel cell includes electrolyte electrode assembly and separators. An annular member and a ring foil are provided between the separators. The annular member is provided around an outer circumferential portion of the electrolyte electrode assembly, and includes grooves for discharging a first exhaust gas FGoff which has been consumed at an anode to the outside of the electrolyte electrode assembly. The ring foil is provided adjacent to a cathode, and extends from a position between an outer end of the electrolyte electrode assembly to a position between the annular member and the separator.
US08247126B2
A method of controlling pressure of a fuel gas in a fuel cell stack is disclosed. The method includes establishing a specification for a fuel gas/oxidant gas delta pressure vs. time value, operating the fuel cell stack, monitoring the fuel gas/oxidant gas delta pressure vs. time value and reducing stress resulting from excessive pressure of the fuel gas by implementing at least one of the following: (1) inducing the fuel cell stack to convert excess fuel gas into electrical current; (2) shutting off supply of the fuel gas to the fuel cell stack; and (3) and raising an operating pressure of the fuel cell stack when the fuel gas/oxidant gas delta pressure vs. time value strays beyond the specification.
US08247123B2
An electric power source control apparatus (50) includes a required electric power decision portion that receives an operation input signal from an outside of an electric power source (20), and decides an amount of electric power required of the electric power source (20), in accordance with the operation input signal; and an electric power source operation portion that operates the electric power source (20) in accordance with the amount of the required electric power. The electric power source operation portion limits an amount of electric power used for heating when the amount of the required electric power is larger than an amount of electric power that can be supplied by the electric power source, during heating.
US08247121B2
Upon stop of electric power generation of a fuel cell a hydrogen shutoff valve is closed, and a cathode is purged. At the same time, an air introducing valve and the purge valve are opened. The air taken in by the compressor is introduced into the anode through the air introducing tube to exhaust the hydrogen remaining in the anode to replace the hydrogen with the air. When the replacement of the hydrogen with the air has been finished, the compressor is turned off and the air introducing valve and the purge valve are opened. After that, if a temperature of the fuel cell is determined to be equal to or lower than a threshold “a”, a cathode-prioritized purge and an anode-prioritized purging are performed.
US08247120B2
A fuel cell system includes an energy conversion module and a fuel module that is detachable from the energy conversion module. The fuel module includes a fuel tank, a fuel module identification member including fuel module data and a fuel filter member. The control module is configured to access the fuel module data from the fuel module identification member. The fuel cell stack is configured to utilize the refined fuel to generate electrical energy.
US08247119B2
In a fuel cell system, a humidifier is attached to an end plate. A pipe connector of a fluid pipe provided at the end plate such as an oxygen-containing gas inlet manifold and a pipe connector of a fluid pipe of the humidifier such as a humidified air supply pipe are connected through a substantially ring-shaped intermediate pipe. O-rings are attached to annular grooves in the outer circumferential portions of the intermediate pipe. One of the O-rings tightly contacts the inner circumferential surface of the pipe connector of the oxygen-containing gas inlet manifold, and the other of the O-rings tightly contacts the inner circumferential surface of the pipe connector of the humidified air supply pipe.
US08247112B2
An object of the present invention is to provide an electrolyte solution for lithium-ion secondary batteries comprising a tetraalkylphosphonium salt which improves the cycle characteristics and safety of lithium-ion batteries, and to provide a lithium-ion secondary battery using the electrolyte solution. Disclosed is an electrolyte comprising a tetraalkylphosphonium salt represented by general formula (1) wherein R1 represents a linear, branched or alicyclic alkyl group having 2 to 6 carbon atoms and R2 represents a linear, branched or alicyclic alkyl group having 1 to 14 carbon atoms, provided that R1 and R2 are different from each other and the total number of carbon atoms in the phosphonium cation is 20 or less; and X represents an anion.
US08247109B2
A battery cover structure includes a removable cover and a main body. The cover defines two cutouts at an end thereof. The main body includes a first housing and a second housing. The first housing defines a through hole. An elastic arm extending from the first housing and is received in the through hole. Two latching blocks respectively extend from two sides of the arm and are respectively engaged in the cutouts of the cover. The arm includes a distal portion. The second housing is integrally formed with the first housing. The second housing includes a flexible operating portion above the distal portion of the arm. When the operating portion is pressed down, the at latching blocks are detached from the cutouts so as to remove the cover.
US08247107B2
A battery pack that enhances the reliability and coupling force of a connection member electrically connecting two protective circuit boards is disclosed. The battery pack includes: a secondary battery including a positive electrode and a negative electrode; a first protective circuit board electrically connected to the battery; a second protective circuit board electrically connected to the first protective circuit board; and at least one conductive plate coupled to one surface of the first protective circuit board and one surface of the second protective circuit board.
US08247098B2
An electrochemical cell comprising: (i) an anode half-cell with an anode, (ii) a cathode half-cell with a cathode, (iii) an ion-exchange membrane arranged between the anode half-cell and the cathode half-cell, the anode and/or the cathode comprising a gas diffusion electrode, (iv) a gap between the gas diffusion electrode and the ion-exchange membrane, (v) an electrolyte feed inlet above the gap, (vi) an electrolyte drain beneath the gap, (vii) a gas inlet, (viii) a gas outlet, and (ix) an electrolyte holding vessel comprising an overflow connected with the electrolyte feed inlet.
US08247092B2
The present invention relates to a cutting tool for metal machining with improved wear properties, comprising a cutting tool substrate of cemented carbide, cermet, ceramics or a super hard material, and a wear resistant coating, wherein the wear resistant coating comprises a PVD Ti—Si—C—N layer, and a method of making thereof.
US08247082B2
There is provided an aluminum alloy brazing sheet having an improved brazability than in the related art while keeping the post-braze strength, workability, corrosion resistance, and the like at respective prescribed or higher levels. An aluminum alloy brazing sheet has a two-layered structure in which on one side of a core material, a brazing material is provided. The core material contains Si: 0.6 to 1.0 mass %, Cu: 0.6 to 1.0 mass %, Mn: 0.7 to 1.8 mass %, Mg: 0.1 to 0.7 mass %, and Ti: 0.06 to 0.20 mass %, and the balance including Al and inevitable impurities. The brazing material includes an aluminum alloy containing Si: 3.0 to 12.0 mass %, the gage of the aluminum alloy brazing sheet is 0.6 to 1.4 mm, and the area ratio of a {001} plane in the core material surface is 0.3 or more.
US08247081B2
A process for joining a stainless steel part and a titanium carbide ceramic part comprising: providing a SUS part, a TiC ceramic part, a Ti foil and a Fe foil; placing the TiC ceramic part, the Ti foil, the Fe foil, and the SUS part into a mold, the Ti foil and the Fe foil located between the TiC ceramic part and the SUS part, the Ti foil abutting the TiC ceramic part, the Fe foil abutting the SUS part and the Ti foil; placing the mold into a chamber of an hot press sintering device, heating the chamber and pressing the SUS part, the TiC ceramic part, the Ti foil, and the Fe foil at least until the SUS part, the TiC ceramic part, the Ti foil and the Fe foil form a integral composite article.
US08247080B2
A coating structure including an outer coating comprising aluminum; and an interlayer disposed between a substrate and the outer coating is provided. The interlayer may include a rare earth metal, a transition metal, or a noble metal. The interlayer may have one or more property of being less responsive to halogen etching relative to the outer coating; having a coefficient of thermal expansion that is greater than the coefficient of thermal expansion of the substrate and less than the coefficient of thermal expansion of the outer coating or vice versa; having a color different from the color of the outer coating; having a electrical conductivity different from the electrical conductivity of the outer coating. A method of making is article is provided. The method may include securing an interlayer to a substrate surface, and securing an outer coating to a surface of the interlayer opposite the substrate.
US08247075B2
It is an object of the present invention to provide: a modified perovskite-type composite oxide, which effectively suppresses elution of A-site metals from a perovskite-type composite oxide, and which can be particularly preferably used as an inorganic filler for a composite dielectric body; a method for producing the same; and a composite dielectric material using the same. The modified perovskite-type composite oxide of the present invention is produced by primarily coating the particle surface of a perovskite-type composite oxide with silica and then secondarily coating it with a coupling agent, characterized in that the layer primarily coated with silica is produced by performing a heat treatment at 800° C. to 1200° C. on hydrolyzed silica obtained by the hydrolysis of tetraalkoxysilane.
US08247065B2
Provided are blends of linear low density polyethylene copolymers with very low density, low density, medium density, high density, and differentiated polyethylenes and other polymers. The invention also includes articles produced from the linear low density polyethylene and polyethylene blends described herein.
US08247064B2
This invention relates to coating a surface wherein the coated surface inhibits foulants such as cell and/or protein and/or prion adhesion or formation. In particular, the coated surface may be part of a medical device which inhibits bacterial adhesion and colonisation, thrombus formation and/or prion, blood protein and/or protein formation.
US08247061B2
Disclosed is a method for calibrating an annular-shaped body which is made of thermoplastic or at least partially crystalline plastic material, to an annular-shaped body which is produced according to the method, and to an oscillating object which is used in the method. Also disclosed is an oscillating object which is used to stimulate oscillations and which is introduced into an annular-shaped body by means of axial forward motion. Localized warming of the annular-shaped body is performed until the glass transition temperature of the material thereof is exceeded by localized contact of the oscillating object with the annular-shaped body. A desired, economical internal measurement having high precision is produced when the calibration section of the oscillating body is immersed into the annular-shaped body.
US08247060B2
A flexible graphene-based metamaterial structure is disclosed that can operate at above liquid helium or liquid nitrogen temperatures, up to room temperature or above in applications similar to those for which a superconductor-based material structure is used. The flexible graphene-based metamaterial structure is formed from a flexible substrate, and a plurality of two-dimensional graphene blocks disposed in an array on the flexible substrate, each graphene block having a plurality of graphene sheets. The lateral dimension of the face of the graphene blocks is dependent on the temperature of operation of the flexible metamaterial structure. The flexible graphene-based metamaterial structure can be used for cloaking, with application in magnetic shielding.
US08247056B2
A label assembly and method of using the same to label articles durably, yet removably. In one embodiment, the label assembly is used to label fabric articles, such as clothing, and comprises (a) an image forming laminate for forming an image on the fabric article, the image forming laminate comprising an ink layer, the ink layer being bondable to the fabric article; and (b) an image removing laminate for removing the image from the fabric article, the image removing laminate comprising a remover layer, the remover layer, upon being activated by heat and/or light, being bondable to the ink layer of the image forming laminate; (c) whereby, upon bonding of the image removing laminate to the ink layer, the bonding between the image removing laminate and the ink layer is stronger than the bonding between the ink layer and the fabric article.
US08247054B2
The present invention relates to a system, method, and composition utilizing a pressure sensitive adhesive (PSA) and/or thermal sensitive adhesive sheet for adhering sheets of preformed thermoplastic road markings, texture and design patterns to concrete, asphalt, wood or composite material surfaces. These markings may be decorative or legend type markings. The system involving the method of applying the product allows for immediate use in a traffic area upon completion of the application to any of the appropriate outdoor surfaces.
US08247053B2
The invention relates to an adhesive composition comprising, relative to its total weight: from 1 to 40% of a polyethylene (A) grafted with a functional monomer or a blend of a polyethylene (A1) with a second polymer (A2) different from (A1), said blend of (A1) and (A2) being co-grafted with an unsaturated functional monomer, the content by weight of unsaturated functional monomer relative to (A) being in the range from 30 to 100000 ppm; from 25 to 98% of a non-grafted polyethylene (B) having a density in the range from 0.900 to 0.965; from 1 to 35% of an elastomeric product (C). The invention also relates to a multilayer structure comprising this composition, said structure being able to serve as protection of metal tubes used for the fabrication of oil pipelines and gas pipelines.
US08247046B2
A tube having walls of multi-layer construction, wherein said multi-layer construction includes one or more sub-layers, each said sub-layer consisting of a woven polymer mesh disposed in between one or more outer layers of material selected from the group consisting of paper, poly-propylene and polyethylene, wherein said tube is formed by affixing said sub-layers to each other while said sub-layers are wound around a mandrel.
US08247044B2
An inkjet recording element is disclosed having a support and, on the support, (a) a porous base layer comprising particles of fumed silica and a hydrophilic binder and (b) a porous gloss layer above the base layer comprising particles of colloidal silica and a hydrophilic binder, wherein the particles of fumed and colloidal silica are anionic. Also disclosed is a method of printing on such an inkjet recording element. The inkjet recording element can potentially have, in some embodiments, the advantages of improved image quality (reduced coalescence) and higher dye ink optical densities.
US08247036B2
A method for making a coaxial cable, the method comprises the steps of: providing a carbon nanotube structure; and forming at least one conductive coating on a plurality of carbon nanotubes of the carbon nanotube structure; a carbon nanotube wire-like structure from the carbon nanotubes with at least one conductive coating; at least one layer of insulating material on the carbon nanotube wire-like structure; at least one layer of shielding material on the at least one layer of insulating material; and one layer of sheathing material on the at least one layer of shielding material.
US08247035B2
This invention offers a method for forming multilayer coating film by successively applying onto a coating object a water-based first coloring paint, water-based second coloring paint and clear paint, and simultaneously baking the resultant first coloring coating film, second coloring coating film and clear coating film, in which the water-based first coloring paint (A) comprises polyester resin and curing agent, the polyester resin containing benzene ring and cyclohexane ring in its molecules, their combined content in the polyester resin being within a range of 1.0-2.2 mols/kg (solid resin content); and that the curing agent is at least one compound selected from the group consisting of isocyanate group-containing compound, oxazoline group-containing compound, carbodiimide group-containing compound, hydrazide group-containing compound and semicarbazide group-containing compound. According to this method, multilayer coating film excelling in smoothness, distinctness of image, chipping resistance and water resistance can be formed by 3-coat-1-bake system.
US08247030B2
A method is provided for controlling copper agglomeration on a substrate and for forming void-free bulk copper metal filling of recessed features in integrated circuits. In one embodiment, the method includes providing a substrate having a topography including a top surface and at least one recessed feature comprising at least a sidewall surface and a bottom surface, depositing a barrier film on the substrate topography, and depositing a metal-containing wetting film on the barrier film. The method further includes physical vapor depositing copper metal on the metal-containing wetting film, where the substrate temperature is sufficiently high to form a smooth copper metal seed layer on the metal-containing wetting film. Void-free bulk copper metal may be plated in the at least one recessed feature.
US08247029B2
The micropattern formation of the invention comprises forming a resist pattern, and then forming a carbon-containing film on the surface of the resist pattern, followed by ashing of the carbon-containing film and a portion of the resist surface constituting the resist pattern. Thus, the discharge state of ashing just after the initiation of discharge is so stabilized that the ashing rate distribution can be improved, and sensitive pattern slimming can be implemented with ease and high precision.
US08247027B2
In the present invention a composite particle including: a first polymeric particle having a diameter of from 100 nm to 3.5 microns including a core and a shell: the core including, when dry, at least one void; and the shell polymer having a calculated glass transition temperature(“Tg”) greater than 50° C.; and a second polymeric particle disposed on the surface of the first polymeric particle, the second polymeric particle having a minimum film-forming temperature of greater than 20° C.; wherein the ratio of the diameter of the first polymeric particle to the diameter of the second polymeric particle is from 1 to 50; and wherein the ratio of the weight of the first polymeric particle to the weight of the second polymeric particle is from 0.1 to 40, is provided. In certain embodiments the composite particle further includes pigment particles having a diameter of from 10 nm to 5 microns disposed on the surface of the composite particle, wherein the ratio of the weight of the pigment particles to the weight of the composite particle is from 0.1 to 10. Also provided is a method for forming the composite particles, a thermosensitive recording material including the composite particles and a method for providing the thermosensitive recording material.
US08247025B2
Techniques for fabricating magnetic nanoparticles are provided. In one embodiment, a method performed under the control of at least one apparatus for fabricating magnetic nanoparticles includes preparing a substrate that defines at least one cavity through a portion thereof, soaking the substrate with a solution, the solution including a multiple number of magnetic nanoparticles, and applying a magnetic field so as to collect at least a portion of the magnetic nanoparticles into the at least one cavity.
US08247008B2
Described are digestive/laxative compositions and methods of manufacture and use of same. In a preferred embodiment, the invention provides for a digestive/laxative composition including actinidin. The actinidin is preferably contributed by inclusion of fruit of genus actinidia, or a product thereof. Preferably, the process for forming the composition includes a method in which the fruit is processed at a temperature below that causing significant degradation of actinidin present, this temperature being preferably in the range of −40° C. to 40° C. Methods of administration of the composition are also described.
US08247007B2
The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
US08247001B2
The present invention relates to compositions comprising one or more anthraquinones for use in the treatment of obesity and related metabolic and liver disease. More particularly it relates to a plant extract fraction rich in anthraquinones including both anthraquinone glycosides and anthraquinone aglycones obtainable from a member of the Leguminosae family, more particularly Cassia seeds. It also relates to a method of obtaining a plant extract fraction rich in anthraquinones.
US08246991B2
Disclosed herein are biocompatible and biodegradable polymers which are useful in tissue engineering; wound healing, coatings, and drug delivery, said polymers comprising one or more ECM-mimetic peptides and one or more biodegradable moieties, wherein the moieties do not comprise an amino acid or residue thereof. Further disclosed herein are methods for making and using the disclosed biocompatible polymers.
US08246983B2
The present invention relates to methods and compositions for the treatment of cancer and for research and analysis of cancer. In particular, the present invention provides encapsulated arsenic anti-cancer compositions with improved properties.
US08246977B2
Transdermal delivery systems for administering sufentanil through the skin are provided. The systems contain a sufficient amount of sufentanil to induce and maintain a constant state of analgesia when applied to a subject. The systems are characterized as having one or more features including a high degree of dosage form rate control over flux of sufentanil from the system, a high net flux of sufentanil from the system through the skin, lack of a permeation enhancer, an adhesive member demonstrating superior shear time, a low coefficient of variation in the net flux of sufentanil from the system, a high delivery efficiency, and a substantially constant steady state net flux of sufentanil from the system. Methods of using the transdermal delivery systems to administer a sufficient amount of sufentanil to induce and maintain analgesia for extended periods when applied to a subject are also provided.
US08246976B2
A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. According to the invention, providing drug having differing crystal sizes as well as drug which is solublized in the pressure-sensitive adhesive composition controls the rate of drug delivery from the pressure-sensitive adhesive composition.
US08246973B2
Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
US08246972B2
This invention relates to the use of an active compound selected from the group comprising a sphingoid base, a sphingoid base derivative or a mixture of two or more these compounds for manufacturing a cosmetic composition suitable for topical application with animals having an at least partly fur covered skin for maintaining and/or repairing the keratoseborrheaic condition of the skin and/or fur.
US08246968B2
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.
US08246965B2
Bacillus isolates and compositions comprising the same are provided. Also provided are methods of inducing systemic acquired resistance to infection in a plant by applying a composition comprising a Bacillus control agent to said plant wherein said plant is capable of producing defense proteins.
US08246963B2
Disclosed is a vaccine for edwardsiellosis and streptococcosis in a fish. Specifically, disclosed is a vaccine for edwardsiellosis in a fish, which comprises inactivated cells of (A) an Edwardsiella tarda strain derived from the target fish, and inactivated cells of (B) an Edwardsiella tarda strain derived from a fish other than the target fish, wherein, when the strain (A) is a typical Edwardsiella tarda strain, the strain (B) is an atypical Edwardsiella tarda strain, whereas when the strain (A) is an atypical Edwardsiella tarda strain, the strain (B) is a typical Edwardsiella tarda strain. Also specifically disclosed is a vaccine for edwardsiellosis and/or streptococcosis in a fish, which comprises the components mentioned above and inactivated cells of (C) Streptococcus iniae and/or Streptococcus parauberis.
US08246953B2
The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat a pathological disorder that is mediated by sclerostin or disease related to bone abnormalities such as osteoporosis.
US08246939B2
A water-free preparation, in particular for application to the lips, which contains a silicone-free phase which contains at least one polybutene and/or polyisobutene, at least one isoparaffin, at least one wax and/or wax ester and optionally conventional adjuvant and additive substances and a silicone-bearing phase which contains at least one fluorosilicone, at least one dimethicone, at least one dimethiconol and optionally a particulate phase and fillers.
US08246938B2
Cosmetic hair treatment agent free from hydrogen peroxide and/or the addition products thereof to organic and inorganic compounds and having, in a cosmetic carrier, at least one surface-active agent chosen from anionic, amphoteric and/or zwitterionic surfactants, and at least one acetylpyridinium derivative of formula (I) for improving the general condition of the fibers, for reducing hair damage in the interior of the hair and for increasing the elasticity of the hair.
US08246934B2
A respiratory dispersion for pulmonary delivery comprises one or more bioactive agents, a suspension medium, and a plurality of perforated microstructures having a mean aerodynamic diameter of less than 5 μm. The suspension medium comprises at least one propellant and permeates the perforated microstructures.
US08246933B2
A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO3, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.
US08246929B2
A method for producing a biocompatible material of the formula NaxKyNbO3, 0≦x≦0.8, 0.2≦y≦1, x+y=1 includes the steps of a) providing a Na-precursor and a K-precursor for NaxKyNbO3, b) mixing the precursors in solution wherein said precursors first react to form a sol and thereafter a gel, c) heat treating the gel to obtain an oxide of the material NaxKyNbO3, 0≦x≦0.8, 0.2≦y≦1, x+y=1. The material can be produced as a film, and the material or film can be provided on the exterior surface of a medical implant that will come into contact with body tissue and/or body fluids upon implantation thereof.
US08246927B2
A chemical vapor deposition (CVD) device is equipped with a reaction vessel tube and a small vessel substrate in an electric furnace and with a heater and a thermocouple at the periphery thereof. A gas supply portion is connected to one of the reaction vessel tubes, and a pressure adjusting valve and an exhaust portion are connected to the other of the reaction vessel tubes, controlled by a control section such that the exhaust portion vacuum-exhausts the reaction vessel tube interior, the heater sublimates the small vessel substrate interior by rising temperature of catalyst iron chloride, and the gas supply portion bleeds an acetylene gas into the reaction vessel tube. As a result, iron chloride and the acetylene gas vapor-phase-react, a silicon oxide surface layer is formed to form growth nucleus of carbon nanotubes, and carbon nanotubes are grown so as to be oriented vertically.
US08246920B2
The present invention provides a method for reducing reagent usage, comprising the steps of providing a retainer, at least one group of loopholes being provided on the sidewalls of the retainer; providing a colorimetric glass, adapted to be inserted into the retainer, for receiving the first reagent to be observed through said loopholes; providing a cap, for capping the colorimetric glass and the retainer into a whole, after the colorimetric glass being inserted into the retainer. The present invention mainly uses a reagent tube with a retainer having a new structure, a colorimetric glass and a cap, storing the first reagent only in the colorimetric glass, and the volume of the colorimetric glass is far less than that of the current reagent tube, thus the usage of the reagents can be reduced effectively.
US08246915B2
Disclosed is a removable cooling module (1), for use in a reactor (20) for carrying out an exothermic reaction, comprising a coolant feed tube (2); a distribution chamber (4); a plurality of circulation tubes (5); and a collection chamber (6); said coolant feed tube (2) having at its first end an inlet (3), for charging the coolant module (1) with coolant, and communicating with said distribution chamber (4) at its second end; each of said circulation tubes (5) communicating with the distribution chamber (4) through a first end and communicating with said collection chamber (6) through a second end; the collection chamber (6) having an outlet for discharging coolant. The modular nature of the invention facilitates removal of individual cooling module (1) from a reactor shell (21).
US08246912B2
An optical detecting apparatus for a bio-chip, the optical detecting apparatus including: a light source system for illuminating a bio-chip with an excitation light; a fluorescent light detecting system for detecting a fluorescent light emitted by the bio-chip; and a light path altering unit for directing the excitation light emitted by the light source system to a bio-chip and directing the fluorescent light emitted by the bio-chip to the fluorescent light detecting system, wherein a cross-sectional area of the excitation light irradiated by the light source system onto the bio-chip is greater than an area of the bio-chip, and the fluorescent light detecting system detects a fluorescent image of the entire bio-chip with a single illumination of excitation light.
US08246911B2
Interactions between molecules that are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides for a method for detecting an analyte, comprising contacting with said analyte a recognition moiety for said analyte, wherein said contacting causes at least a portion of a plurality of mesogens proximate to said recognition moiety to detectably switch from a first orientation to a second orientation upon contacting said analyte with said recognition moiety; and detecting said second orientation of said at least a portion of said plurality of mesogens, whereby said analyte is detected.
US08246909B2
A method measures a property of a germicidal solution in an endoscope processor spectroscopically by placing a quantity of the solution into a cuvette and passing a light therethrough. A reservoir receives a quantity of the solution and bubbles are filtered out via a cross-flow filter prior to putting a sample therefrom into the cuvette for measuring.
US08246908B2
By the conventional technique for dispensing more than one reagents accurately, the system is complicated and thus a compact and inexpensive system is difficult to realize. In the present invention, the pressurized dispensing system utilizing a capillary is realized, and in addition, in order to reduce the leakage of reagents different from the reagent dispensed, by forming air layers at the tips of the capillaries after dispensing, a compact, simple, inexpensive analysis apparatus is realized.
US08246907B2
An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.
US08246904B2
A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam.
US08246896B2
The invention relates to a molding composition which is embodied as a molding composition, a thus produced molded body as a molded body, and a method for producing said molded body comprising a surface structure.
US08246868B2
A W/O emulsion is produced from an aqueous solution containing a substance to be entrapped in a vesicle in a dissolved or suspended state and an oil phase containing an emulsifier; subsequently, the W/O emulsion is cooled to a temperature at which the aqueous solution of the W/O emulsion becomes a frozen particle and the oil phase maintains a liquid state, and the oil phase is removed; thereafter, an oil phase containing a vesicle constituent lipid is added to the frozen particle, and the obtained mixture is then stirred, so as to substitute the emulsifier on the surface of the frozen particle with the vesicle constituent lipid; and thereafter, an external Water phase is added to the frozen particle coated with a lipid membrane, so as to hydrate the lipid membrane by the external water phase. This process achieves a high entrapment yield of a desired substance while controlling desired physical properties such as particle diameter.
US08246861B2
A method for making a carbon nanotube composite includes providing a free-standing carbon nanotube structure and a reacting liquid with a metal compound dissolved therein, treating the carbon nanotube structure by applying the reacting liquid on the carbon nanotube structure, and heating the treated carbon nanotube structure in an oxide-free environment to decompose the metal compound.
US08246854B2
This invention relates to organic catalysts comprising iminium or oxaziridinium moieties, cleaning compositions comprising such catalysts; and processes for making and using such catalysts and cleaning products.
US08246853B2
The present invention relates to maintaining the fundamental physical properties of a liquid alkali metal with dispersed nanoparticles which is such that nanoparticles are uniformly dispersed and mixed in a liquid alkali metal used in heat exchange, cooling and other applications, and suppressing the reaction of the liquid alkali metal with dispersed nanoparticles. Provided is a method of manufacturing a liquid alkali metal with dispersed nanoparticles by dispersing nanoparticles in a liquid alkali metal. In this method, the nanoparticles are made of a metal having a large atomic bonding due to a combination with the liquid alkali metal compared to the atomic bonding of atoms of the liquid alkali metal and a metal having a large amount of charge transfer is used in the nanoparticles. The liquid alkali metal is selected from sodium, lithium and sodium-potassium alloys, and the nanoparticles to be dispersed are made of transition metals, such as titanium, vanadium, chromium, iron, cobalt, nickel and copper.
US08246851B2
Disclosed is a nonflammable refrigerant composition consisting of pentafluoroethane in an amount from 62% to 67% based on the weight of the composition, a second component that is selected from 1,1,1,2-tetrafluoroethane, 1,1,2,2-tetrafluoroethane, and mixtures thereof in an amount from 26% to 36% by weight; and an ethylenically unsaturated or saturated hydrocarbon compound that is at least 70% isobutane in an amount of from 1% to 4% by weight and up to 5% by weight based on the weight of the composition of another fluorohydrocarbon. The composition optionally may further include at least one additive, lubricant or combination thereof.
US08246849B2
To provide a magnetic powder production method, a magnetic sheet production method, and an antenna module production method that are capable of reducing a size of magnetic particles, achieving thinning and a low loss, and improving magnetic permeability without lowering it. At least two oxide-based magnetic materials are mixed, preliminarily calcined, and pulverized. The pulverized magnetic materials are typically formed into a paste by being dispersed in an organic solvent, and the magnetic materials are applied onto a film after being subjected to defoaming processing. Accordingly, a sheet-like magnetic material is formed. The sheet-like magnetic material is cut into predetermined sizes so as to be fragmented into particles, with the result that magnetic particles are formed.
US08246848B2
There is provided a production process of a heat-ray shielding film-formed base member comprising the steps of mixing a sol solution, formed by using a starting raw material of trialkoxysilane or trialkoxysilane and tetraalkoxysilane, with a solution in which tin-doped indium oxide ultra-fine particles are dispersed, to make a treatment agent; and applying the treatment agent to a base member. In this production process, the treatment agent has an organic solvent having a boiling point of 100-200° C. as a dispersion medium, and the application is conducted by a means by bringing a member retaining the treatment agent into contact with the base member or by a means by spraying the treatment agent, thereby adjusting haze value of the film to be formed to 0.5% or less.
US08246845B2
A pit is formed from a stack comprising at least one first layer formed by a material able to change physical state and a second layer made of the same material as that forming the first layer, but in a different physical state. An area of the first layer is treated to make said area go from its initial physical state to the physical state corresponding to that of the second layer. A selective etching step is then performed to eliminate said area of the first layer and the area of the second layer initially covered by the treated area of the first layer. Advantageously, said material is a phase transition material.
US08246834B2
A method for separating a sample using high pressure flash chromatography is provided. The method comprises the steps of: i) providing a pressurized vessel containing an adsorption material; ii) pressurizing a compressible fluid, optionally containing a cosolvent, to create a mobile phase; iii) premixing the sample with the mobile phase or optionally placing the sample in the pressurized vessel; iv) eluting the mobile phase through the pressurized vessel, to obtain a separated sample; v) heating the mobile phase containing the separated sample after the mobile phase exits the pressurized vessel to remove the compressible fluid; and iv) collecting the separated sample. The pressurized vessel contains an adsorption material having a particle size of 10-100 microns, and the pressure of the adsorption vessel is held at 50-350 bar during elution. Also provided is an apparatus for carrying out the above method.
US08246829B2
A modularizable system for residential water treatment having a low energy requirement to process water for reuse at the residence which results in a reduction in the amount of fossil fuels required to power large water processing stations and transfer water from water plants to individual residences is disclosed. The system increases availability of water at the residential level in areas where water is a limited or limiting resource (e.g., in arid climates). Furthermore, the amount of water a residence uses in a given cycle is more efficient.
US08246826B2
The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
US08246821B2
A bubbler is positioned within a solvent reservoir of a chromatographic system with its opening near the bottom of the system to measure the pressure of solvent. The bubbler may use air or may use helium or some other gas so that the solvent can be purged of excess air while its level is being monitored by the bubbler. The bubbler provides a depth signal to a microcontroller that records the drop in pressure and projects a low level of pressure at which point solvent should be replenished. The microprocessor may provide a signal to the operator or terminate operation or automatically replenish solvent depending upon the program.
US08246819B2
The automatic transmission fluid filter includes a plastic upper case having an outlet port, a plastic lower case having an inlet port, and a filter element including a filter medium and a plastic holder frame holding the periphery of the filter medium and held between the upper case and lower case, at least one of the upper case and lower case including a pair of joint portions respectively joined to opposite walls a of the holder frame, and a connecting wall connecting the pair of joint portions and having a circular arc longitudinal cross section protruding outward of one case.
US08246814B2
A process for upgrading crude oil fractions or other hydrocarbon oil feedstreams boiling in the range of 36° to 520° C., and preferably naphtha and gas oil fractions boiling in the range of 36° to 400° C., employs a solid adsorption material to lower sulfur and nitrogen content by contacting the hydrocarbon oil, and optionally a viscosity-reducing solvent, with one or more solid adsorbents such as silica gel or silica, silica alumina, alumina, attapulgus clay and activated carbon in a mixing vessel for a predetermined period of time; passing the resulting slurry to a membrane separation zone, optionally preceded by a primary filtration step (i.e., single stage or multiple stages), to separate the solid adsorption material with the adsorbed sulfur and nitrogen compounds from the treated oil; recovering the upgraded hydrocarbon product having a significantly reduced nitrogen and sulfur content as the membrane permeate; mixing the solid adsorbent material with one or a combination of aromatic solvents such as toluene, benzene, the xylenes and tetrahydrofuran to remove and stabilize the sulfur and nitrogen compounds; transferring the solvent to a fractionation tower to recover the solvent, which can be recycled for use in the process; and recovering the hydrocarbons that are rich in sulfur and nitrogen for processing in a relatively small high-pressure hydrotreating unit or transferring them to a fuel oil pool for blending.
US08246801B2
Disclosed a support structure of an electroosmotic member including: a support structure; an opening formed in the support member in which an electroosmotic member is disposed; and at least one of an elastic piece to separate the opening and the space from each other and to support the electroosmotic member, a cushioning filled in a gap between a wall of the opening and an edge of the electroosmotic member to support the electroosmotic member, and a projection provided on a wall of the opening to support the electroosmotic member, wherein the elastic piece, the cushioning and the projection supports the electroosmotic member which absorbs an impact or a vibration, and when the impact is applied to the support member (housing), an impact load applied to the electroosmotic member can be suppressed and thus, even when the impact is applied, it is possible to prevent the electroosmotic member from being damaged.
US08246783B2
A roller for thermal pressure treatment of web-type media such as paper or non-wovens, provided with an inner heating system and comprising a base body made of hardened and tempered wrought steel or alloyed cast iron, an intermediate layer applied to the surface thereof and a hard wearing layer applied thereon. Peripheral bores or canals extending parallel to the axis are arranged in the base body of the roller at a regular distance from the surface, being distributed in a regular manner on the circle formed about the roller axis. The materials used and the arrangement of the peripheral bores are such that the roller can be used in calanders in a method wherein the surface temperatures of the roller exceed 140° C., the heating capacity is more than 35 kW/m2, operational speeds are more than 1200 m/min, line pressures are greater than 250 kN/m and the processed webs of material weigh more than 45 g/m2 and have a degree of moisture of over 5%.
US08246779B2
Methods and apparatus for maintaining sulfur concentration in the chemical recovery cycle of a Kraft pulping process. A portion of the recovery boiler ash is dissolved, treated to remove solids, and combined with an acid to provide a solution. The recovery boiler ash may be dissolved directly in the acid. The acid may be effluent from a chlorine dioxide generator. The resulting solution is maintained in a fully dissolved state and subjected to an acid separation step to provide a sodium sulfate enriched phase, which may be used to maintain sulfur concentration in the Kraft pulping process, and a sulfuric acid phase. Chlorine ions can be separated with the sulfuric acid phase. The sulfuric acid phase can be recycled to the chlorine dioxide generator.
US08246768B2
A high-tensile steel plate of low acoustic anisotropy and high weldability having yield stress of 450 MPa or greater and tensile strength of 570 MPa or greater and a process for producing the steel plate are provided. The steel has an Si content of 0.10% or less, thereby achieving a volume ratio of island martensite of 3% or less, contains Nb≧0.025% and Ti≧0.005% so as to satisfy 0.045%≦[Nb]+2×[Ti]≦0.105%, contains Nb, Ti, C and N in ranges such that the value of A=([Nb]+2×[Ti])×([C]+[N]×12/14) is 0.0022 to 0.0055, and has a steel structure wherein bainite volume ratio is 30% or more and pearlite volume ratio is less than 5%.
US08246765B2
A method for inhibiting growth of tin whiskers is provided. The method includes providing a metal substrate, forming a tin layer to cover the surface of the metal substrate, and treating the metal substrate covered the tin layer by an annealing process, wherein the annealing process is performed at 400° C.-600° C. and the surface of the tin layer is subsequently inhibited from growing tin whiskers.
US08246762B2
The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.
US08246759B2
There is provided a substrate processing apparatus capable of stably holding a substrate and properly processing the substrate. The substrate processing apparatus is an apparatus that processes a substrate while rotating the substrate, with a place surface of the substrate being oriented in a horizontal direction. The substrate processing apparatus comprises a table including a rotatable base plate having a plurality of projecting members projected outward, and a rotation driving mechanism that rotates the base plate. The table can rotatably hold the substrate such that the projecting members contact the substrate from below with a gap formed between the substrate and the table. The substrate processing apparatus further comprises a pressure adjusting apparatus including a suction duct line having one end thereof being opened to the gap, and a suction mechanism connected to the other end of the suction duct line.
US08246754B2
A process for removing ink from a printed media substrate. Such process includes the step of providing a media substrate including an ink printed image wherein the ink composition or the media substrate contains photolabile entities. Then the process includes the step of applying UV light on the printed substrate wherein the emitted UV light has a wavelength value which is below the threshold wavelength of the photolabile entities.
US08246751B2
The present application provides a pulsed detonation cleaning system for cleaning an enclosed structure. The pulsed detonation cleaning system may include a pulsed detonation combustor cleaner and an external fuel-air flow. The pulsed detonation combustor cleaner delivers the external fuel-air flow into the enclosed structure and ignites the external fuel-air flow to clean the enclosed structure.
US08246732B2
An exhaust gas cleaning apparatus according to the present invention includes a wall member configured to form a gas passage for allowing an exhaust gas to pass therethrough, and a mist nozzle and a water film nozzle disposed in the gas passage. The mist nozzle forms mist in the gas passage, and the water film nozzle forms water film in the gas passage. The mist nozzle is disposed further toward the upstream side in a flowing direction of the exhaust gas than the water film nozzle. Plural sets of the mist nozzle and the water film nozzle may be provided.
US08246720B2
An electrostatic aerosol concentrator includes an airflow chamber with alternately energized and grounded electrode elements that work in concert to impart radial inward motion to charged aerosol particles and focusing them toward an enriched aerosol outlet. Aerosol particles entering the airflow chamber may carry a positive or negative charge naturally, or a charge may be induced on the particles using a charging section located upstream of the aerosol inlet. Natural or induced charges on the aerosol particles may be used to selectively concentrate subpopulations of aerosol particles from a mixture of particles. For example, bacterial spores or aerosolized viruses may be selectively enriched without concentrating other aerosol particles.
US08246715B2
A method of adjusting a vortex of molten metal comprises providing a scrap charging vessel. The scrap charging vessel includes a vortex control plate having an outlet orifice that can be positioned at a bottom of the vessel so that the outlet orifice is in fluid communication with an outlet passageway of the vessel. A vortex level is estimated or observed. A size of the outlet orifice of the vortex control plate is selected that can produce a desired level of a vortex in the vessel that is the same as or different than the estimated or observed vortex level. The vortex control plate of the selected outlet orifice size is positioned in the vessel. Molten metal is moved into an inlet opening of the vessel and forms the vortex at the desired level in the vessel.
US08246713B2
The present invention provides a process for preparation of a fertilizer, particularly a process for preparation of a nano long-acting selenium fertilizer. The present invention provides a process for preparation of a long-acting selenium fertilizer, including: mixing a selenium rich carbonaceous siliceous rock powder having 30-95% of nano particles relative to total volume and a selenium content of 500 μg/g or more with a liquid having pH of 8.0-10.0. The liquid having pH of 8.0-10.0 is obtained by mixing KOH, K2CO3 and 20% ammonia in a weight ratio of 10:1:2, and then adjusting pH with water.
US08246712B2
Disclosed is a soapstock treatment apparatus which can treat a soapstock produced during a plant oil production process within a short period and with a high degree of efficiency. As shown in FIG. 1, the soapstock treatment apparatus includes a reactor 20 configured to oxidatively decompose a soapstock, an electric heating coil 23 configured to heat water in the reactor 20 at 650° C. which is not less than the critical temperature of water, a high-pressure pump 13 configured to pressurize the water in the reactor 20 at 17 Mpa which is less than the critical pressure of water, and a compressor 33 configured to pressurize the water in the reactor 20 at 17 Mpa which is less than the critical pressure of water. Also, an exhaust pipe 41 for discharging a reaction gas generated by the oxidative decomposition treatment and a waste pipe 51 for discharging a solid (inorganic) residue generated by the oxidative decomposition treatment are connected to the reactor 20. Furthermore, a gas-liquid separator 44 for separating the reaction gas into a gas substance and a liquid substance are connected.
US08246707B2
A filter arrangement includes a media construction comprising a corrugated sheet secured to a flat sheet rolled into a coiled construction. A frame and a first seal member are provided. The frame secures the first seal member to the coiled construction. The first seal member is preferably oriented to form a radial seal with a housing. A second seal member is secured to the outer annular surface of the coiled construction. The second seal member includes a gasket extension having first and second opposite ends; an attachment portion; and a protrusion extending from the attachment portion. The second seal member is preferably oriented to form an axial seal with a housing. Air cleaners preferably utilizing filter arrangements as described herein operably installed within housings. Methods of installing, filtering, assembling, and servicing preferably include arrangements as described herein.
US08246698B2
Disclosed herein are solubility changeable dye compositions, methods of preparing such compositions and methods of using them. The composition includes a dye component linked via a linker moiety to a stimulus responsive hydrophobic moiety which modulates the solubility of the dye, wherein the hydrophobic moiety is configured to be de-linked from the dye component on exposure to a stimulus and render the dye component more hydrophilic.
US08246697B2
A mixture of amides of the following formula (I) is disclosed wherein —R1 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms; —R2 and R3 represent independently, a hydrogen atom or a linear or branched alkyl group having 1 to 5 carbon atoms which is optionally hydroxylated, provided that R2 and R3 are not a hydrogen atom at the same time; -n has a value in the range of 0.2 to lower than 3; characterized in that said mixture comprises: -amides (a) of formula (I) wherein R represents a C6-C24 alkyl or alkenyl group having even number of carbon atoms and at least a 95 wt. % of linearity; and -amides (b) of formula (I) wherein R represents a C5-C23 alkyl or alkenyl group having odd or odd and even number of carbon atoms and a 35-85 wt. % of linearity; and cosmetic compositions comprising said mixture, particularly dying compositions.
US08246694B2
A prosthesis comprising an elastomeric locking liner sized and configured to surround a limb of a patient about a knee joint, the liner having an inner surface for facing the limb of the patient and an outer surface defining an anterior region and a posterior region which are demarcated by an imaginary plane extending midway between the front most portion and rear most portion of the limb along the length of the limb, wherein the anterior region has an anterior material secured thereto and the posterior region has a posterior material secured thereto and the anterior and posterior materials having equal transverse elongation, and the anterior material having a longitudinal elongation greater than the longitudinal elongation of said posterior material, whereby when said prosthesis is donned onto a limb of a patient over the knee and the limb is flexed about the knee, buckling of the prosthesis about the knee is substantially reduced or eliminated and wherein the distal end of the liner includes an insert member adapted to receive a connector for locking the liner to a prosthetic socket when worn on a residual limb of an amputee.
US08246691B2
A bioabsorable stent is disclosed. The stent is made of a bioabsorable material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.
US08246682B2
An in-situ formed laminoplasty implant comprising an expandable bag containing a flowable, hardenable composition, wherein the implant may be shaped to act as a laminoplasty strut and be rigidly connected to a prepared lamina space.
US08246677B2
A method of delivering a replacement prosthetic valve to a previously implanted prosthetic valve including the steps of compressing a replacement prosthetic valve having an expandable stent within a sheath of a delivery system, wherein the delivery system comprises a proximal end, a distal end, and a centering structure positioned between the proximal and distal ends, advancing the delivery system and compressed replacement prosthetic valve into a vessel of a patient until the distal end of the delivery system is positioned adjacent to a second side of a previously implanted prosthetic valve, deploying the centering structure to radially reposition the distal end of the delivery system, further advancing the delivery system toward the previously implanted prosthetic valve, and deploying the replacement prosthetic valve.
US08246675B2
A kit for implanting in a duct, which includes a tubular endoprosthesis and a prosthetic valve is disclosed. The prosthetic valve includes a carrier frame that is radially deformable in elastic manner relative to a central axis of the tubular endoprosthesis between a deployed, implanted position, and a folded, implanting position. The carrier frame is urged elastically towards its deployed position. A flexible shutter is connected to the carrier frame. The shutter is deformable between an obstruction position in which it is extended transversely, and a release position in which it is contracted transversely under to allow a fluid to flow through the carrier frame. The carrier frame also includes an integrated centripetal compressing mechanism for centripetally compressing the carrier frame towards folded position.
US08246661B2
A bone plate (1) having an upper side (2), a bone-sided lower side (3), a first end (11), a second end (12) and several plate holes (4) arranged between the two ends (11, 12) and connecting the upper side (2) to the lower side (3), the plate holes being provided for receiving bone screws. Two of the plate holes (4) are formed by a combination of two partially overlapping boreholes (5, 6) of different type. The first (5) of the two boreholes is a circular cylindrical bore, having an internal thread (7) and a cylinder axis (9). The second borehole (6) has a cone axis (10) and tapers from the upper side (2) to the lower side (3) in the form of a frustum of a cone. The second borehole (6) is provided with an internal thread (8). The cylinder axis (9) is situated at a distance A from the cone axis (10), where A is different than zero.
US08246658B2
A spinal connector assembly includes a connector body having a first receiver portion, a second receiver portion, and a threaded portion extending axially from the second receiver portion. A washer member coupled with the connector may rotate about the rotational axis and translate along the rotational axis. A lock member threadingly engages the threaded portion of the connector body to exert an axial force onto a second implant member to compress the second implant member within a channel in the washer member which in turn displaces the washer member into compressed engagement with a first implant member to thereby lock the washer member and the second implant member at a select angular orientation relative to the connector body, and the axial force also compresses the first implant member into clamped engagement within the first passage of the connector body.
US08246654B2
The present invention provides a transfacet fixation assembly, including: an engaging bolt; and a receiving bolt selectively coupled to and engaged with the engaging bolt at an angle of between about 30 degrees and about 120 degrees; wherein each of the engaging bolt and the receiving bolt is configured to be disposed through a hole or bore formed through one of a plurality of bony structures making up a portion of a facet joint of a spine. Optionally, the engaging bolt includes a spherical distal end for engaging a locking sleeve disposed at a distal end of the receiving bolt.
US08246650B2
A removable filter for capturing thrombi in a blood vessel. The filter comprises a plurality of primary struts having first ends connected to each other to define a central axis of the filter. Each primary strut has a curved member extending from the central axis and terminates at an anchoring hook to engage the blood vessel at a first axial plane. The filter further comprises a plurality of secondary struts connected to the curved members of the primary struts and extending therefrom to a free end at a second axial plane to centralize the filter in the blood vessel.
US08246645B2
A lancet assembly includes a lancet and a lancet holder that houses the lancet, whereinthe lancet includes a lancet body, a lancet cap and a pricking component, the pricking component is situated in both of the lancet body and the lancet cap, the tip of the pricking component is covered with the lancet cap, and the lancet cap and the lancet body are integrally connected together by a bridging componentwhen the lancet cap is pressed in the pricking direction with the lancet body attached to the lancet holder, the bridging component is broken so that the lancet cap is separated from the lancet body. Thereafter,when the separated lancet cap is pressed further: in the pricking direction, the separated lancet cap moves to a position that is off the pricking pathway of the pricking component.
US08246642B2
An ultrasonic medical instrument having a handpiece and medical ultrasonic blade assembly including a vibration antinode, a handpiece, and a medical ultrasonic blade. The blade is threadably engaged by the handpiece proximate the vibration antinode. The blade is in ultrasound-transmitting physical contact with the handpiece proximate the vibration antinode and apart from where the medical ultrasonic blade is threadably engaged by the handpiece. A medical-instrument connection assembly for transmitting ultrasonic vibrations includes first, second, and third connecting members. The first connecting member is adapted to be ultrasonically vibrated and has a longitudinal axis. The second connecting member is capable of being positioned to be substantially coaxially aligned with the longitudinal axis and in ultrasound-transmitting physical contact with the first connecting member. The third connecting member surrounds, and is rotatably or fixedly attached to, the second connecting member and is threadably engageable with the first connecting member.
US08246640B2
A tissue cutting device includes a sizing element which detects the diameter of the vessel in which the cutting device is positioned. The sizing element is coupled to the cutting element so that the amount of the cutting element that is exposed varies in response to movement of the sizing element.
US08246639B2
A device for clamping a tissue, the device having a clamp (100) with at least one magnetic portion. In at least one embodiment, the clamp (100) has two oppositely polarized magnets (102, 104) and a mounting structure (106) for the magnets. In some other embodiments, a clamp has an electromagnetic collar (500) and a power source (300) to provide power to the collar (500) via an electrical connector (302). In at least some embodiments, the clamps (100) may also be electromagnetic.
US08246633B2
A manipulator includes a yaw axis and a pitch axis disposed as joints on a distal end of a joint shaft and which are actuatable by motors, a needle variable in orientation by the joints, a coaxial connector disposed at a position closer to a proximal end of the manipulator than the joint shaft, and a coaxial cable providing within the joint shaft at least a portion of an electrical connection between the coaxial connector and the needle. A small board providing an impedance matching circuit, and which includes a coil and a capacitor, is interposed between the coaxial connector and the coaxial cable.
US08246624B2
Embodiments described herein provide systems and methods for inserting a spinal stabilization rod. A rod insertion tool can include a body defining a passage, a pivot rod disposed in the passage and a rod retaining member. Movement of the pivot rod can cause the rod retaining member to rotate and consequently the spinal stabilization rod to rotate. The rod insertion tool can be sized to fit through channels in sleeves used during implantation of a spinal stabilization system.
US08246622B2
A device for removing material from within the body, includes an elongated element formed from hollow segments sequentially interconnected at effective hinges. The device assumes an insertion configuration for insertion of the segments sequentially through an opening of a first dimension into the body. A portion of the elongated element inserted into the body progressively assumes a material removing configuration in which a relative position of each segment relative to an adjacent segment is delineated by the effective hinge together with additional abutment surfaces defining a fully deflected state of the effective hinge. The material removing configuration has at least two dimensions exceeding the first dimension. At least two of the segments are formed with at least one cutting configuration deployed so as to collect material into a hollow volume of the segment during progressive formation of the material removing configuration as the elongated element is advanced.
US08246619B2
An endoscopic forceps includes a housing having a shaft attached thereto that supports a pair of jaws disposed at a distal end thereof. A drive assembly having a drive shaft with a proximal end is operable to move the jaws relative to one another from an open to closed positions. A knife assembly is operable to advance a knife through tissue disposed between the jaws and includes a flange disposed thereon. A knife lockout is included that has a flange configured to engage the proximal end of the drive shaft and a lockout arm configured to engage the flange of the knife assembly to prevent movement thereof. Movement of the jaws to the closed position causes the proximal end of the drive shaft to engage the flange on the lockout which causes the lockout arm to disengage the flange on the knife assembly to permit advancement of the knife.
US08246615B2
A microwave ablation system includes a generator including a first energy source, a second energy source and a diplexer, the diplexer multiplexes a first energy from the first energy source and a second energy from the second energy source. The system also includes a cable including a center conductor and an outer sheath where the multiplexed energy is transmitted through the center conductor. In addition an antenna is provided that is operable to receive the multiplexed energy from the center conductor and to deliver the multiplexed energy to a region of tissue. The outer sheath acts as a return path of the second energy to the second energy source. A sensor is also provided that measures at least one parameter of the second energy generated by the second energy source and the second energy returned from the region of tissue.
US08246613B2
A method for the treatment of skin including the steps of determining the skin depth for energy absorption necessary for treatment; and generating a spot size for energy impinging on the skin to provide a desired amount of energy to the desired depth for treatment. In one embodiment the selected spot size has a small diameter. In another embodiment the spot diameter is narrower than the spacing between adjacent hairs on the skin. In another aspect the invention relates to an apparatus for the treatment of skin including a source of energy; and a means for selecting a spot size for energy from the source impinging on the skin to provide a desired amount of energy to a desired depth for treatment. In another embodiment the apparatus includes an interlock to prevent the laser from producing light unless the source is positioned to irradiate only the skin.
US08246600B2
A multiple catheter assembly (100) including a first catheter (110) having a first proximal end region (112), a first distal end region (114) terminating in a first distal tip (116), and an outer surface (120) defining at least a first lumen (122) extending longitudinally therethrough between a first distal and a first proximal opening. The assembly (100) also includes a second catheter (130) having a second proximal end region (132), a second distal end region (134) terminating in a second distal tip (136), and a second outer surface (140) defining at least a second lumen (142) extending longitudinally therethrough between a second distal and a second proximal opening. The first (122) and second (142) lumens are independent from each other for facilitating simultaneous flow in opposite directions. The outer surfaces (120,140) of the first and second catheters are releasably joined for allowing the first and second distal tips (116,136) and first and second proximal end regions (112,132) to be at least partially longitudinally split from each other. A method of inserting the catheter assembly (100) is also provided.
US08246597B2
A pant-type wearing article configured so as to prevent a lateral zone of a front waist region and an associated lateral zone of a rear waist region which should remain fastened together from being needlessly disengaged from each other. In the pant-type wearing article an outer surface of a base sheet strip constituting a front fastener component is bonded to a fixed region defined on an inner surface of a front lateral zone. The front lateral zone includes a free region to which the base sheet strip is not bonded. The free region normally takes a posture folded back in a waistline direction so that an outer surface of the front lateral zone lies inside.
US08246596B2
A disposable absorbent article may comprise a chassis and a pair of longitudinally disposed barrier cuffs. Each cuff may contain a barrier zone, an attachment zone, and a transition edge separating the barrier zone and attachment zone. The barrier cuffs exhibit a cuff span and a cuff height at a given cross-section through a crotch point and an end region. The absorbent article exhibits a cuff span ratio, defined as a maximum cuff span as measured in the end region of the barrier cuff divided by a cuff span as measured at the crotch point, of greater than 1. The absorbent article exhibits a cuff height ratio, defined as a cuff height as measured at the crotch point divided by a minimum cuff height as measured in the end region, of greater than 1.
US08246588B2
The invention concerns an insertion device for inserting a medical device into the subcutaneous or intramuscular area of a patient. More specifically, this invention relates to an insertion device comprising pivoting and guiding means for moving a penetrating member from a position, where the penetrating member is not pointing into the direction of insertion, to a position, where the penetrating member is pointing into the direction of insertion. The inserter device comprises a housing (15) encompassing a penetrating member (9), said housing comprising a top section (14) and a lower section (16), wherein said insertion device (1) comprises pivoting means (27, 31, 41, 43) and guiding means (10, 19, 16s, 31s, 18s) providing one or more pivoting movement(s) of the penetrating member (9) from a first position, where the penetrating member (9) is not pointing into the direction of insertion, to a second position, where the penetrating member (9) is aligned with the direction of insertion, to a third position, where the penetrating member (9) protrudes the housing (15) and the penetrating member (9) is aligned in the direction of insertion. The guiding means (10, 19, 16s, 31s, 18s) are adapted to provide a longitudinal movement of the penetrating member (9) from the second to the third position.
US08246581B2
A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that holds a volume of the liquid medicament received from the reservoir and displaces substantially all of the volume of the liquid medicament when actuated, and at least a first valve, a second valve, and a third valve. The valves establish fluid connection between the reservoir and the pump when in a first valve configuration and establish fluid connection between the pump and the outlet when in a second valve configuration. At least two of the valves isolate the outlet from the reservoir when the valves are in the first valve configuration.
US08246579B2
The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 24, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a handpiece 50 applied to a surgical area for infusing irrigation fluid and for aspirating a biological material, conduits 60 and 62 connecting the handpiece to each of the source of irrigation fluid and the collection cassette and means 70 for isolating the pump from the handpiece to prevent creation of vacuum within the conduit 62 and the collection cassette 30 after receiving a stop signal.
US08246576B2
Described herein is a medical device that has a collapsed configuration and an expanded configuration wherein one or more polymeric network layers are applied to the substrate and microparticles embedded in the polymeric network. The polymeric network layer or layers is/are configured to retain the microparticles when the device is in a collapsed configuration and to release the microparticles when the device is in an expanded configuration. Methods for delivering a therapeutic agent using the device and making the device are also disclosed.
US08246573B2
A medical device system comprises a reservoir configured to store a therapeutic fluid and a medical pump configured to deliver the therapeutic fluid from the reservoir to a patient. The system also comprises a sensor that can detect a characteristic associated with the pump and a processor to determine if the characteristic detected indicates the reservoir is empty or near empty. The characteristic may comprise a property associated with the energization of an actuation mechanism configured to be energized to provide a pump stroke. The characteristic may also comprise a characteristic of a noise made by an actuator within the pump at the end of a pump stroke.
US08246565B2
Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components.
US08246563B2
A cardiorenal patient monitoring system comprising, either implanted or non-implanted device(s), remote peripheral device(s), computer network(s), host, and communication means between the device(s), computer network(s), and host. The preferred embodiment shows an advanced patient monitoring system for using an implanted cardiac device and a dialysis machine in renal therapy. In addition, the method of advanced patient monitoring is in conjunction with the advanced patient monitoring system is disclosed.
US08246560B2
The invention relates to a hand brace for immobilizing and adjustably positioning one or more digits of the hand, and more specifically, to a brace having a flexible sheet member for application to a wrist and hand, at least one adjustable stabilizing member extending the length of the sheet member that is sufficiently rigid to maintain joints at a desired angle of flexion, a semi-rigid member positioned against the flexible sheet member for protecting and supporting joints of the hand and defining an opening for relieving pressure on a joint, and straps for adjustably securing the invention to the hand. Advantageously the invention immobilizes the hand such that the fourth and fifth metacarpophalangeal joints of the hand are positioned at a desired angle of flexion and fourth and fifth interphalangeal joints of the hand are positioned at a desired angle of extension.
US08246550B2
A Comprehensive Integrated Testing Protocol (CITP) incorporates precise measurements of the dynamic and the static lung volumes and capacities at V30 for routine infant lung function testing. The static functional residual capacity (sFRC) in infants is measured after a short hyperventilation induces a post-hyperventilation apnea (PHA) that abolishes the infant's breathing strategies and creates a reliable volume landmark. A measurement of the sFRC is then obtained by inert gas washout; e.g., by measuring the volume of nitrogen expired after end-passive expiratory switching of the inspired gas from room air to 100% oxygen during the PHA. A true measurement of the total lung capacity (TLC) is obtained from the sum of (1) the passively exhaled gas volume from a Pao plateau of 30 cm H2O through a pneumotachometer (PNT) by integrating the flow signal to produce volume, which is the inspiratory capacity (IC), and (2) the sFRC. From intrasubject TLC and residual volume (RV), the difference is a reliable estimate of the slow vital capacity (SVC). Similar measurements may be obtained with a fastened squeeze jacket for comparison. Actual airway opening pressure (aPao) is measured during a 0.20 s airway occlusion after halting the inflating airflow and prior to activating the jacket inflation. An open mouth is maintained during forced expiration in order to generate an oronasal instead of a forced expiration.
US08246548B2
Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning.
US08246545B2
A phased array ultrasound transducer is made from a plurality of independently excitable elements that are arranged in a row in the azimuthal direction, configured so that azimuthal aiming of an outgoing ultrasound beam is controlled by timing the excitation of the elements. The geometry of the elements is configured to focus the outgoing beam in the elevation direction so as to improve the images of target regions located at or about a particular radial distance. In some embodiments, this is accomplished by forming each element from a plurality of subelements that are stacked in the elevation direction, with the subelements of any given element all (a) wired together and (b) positioned at about the same distance from a substantially rod-shaped focal region.
US08246536B2
A treatment tool insertion channel of an endoscope, which is arranged through an inside of an insertion part that includes a flexible tube and a bendable part, includes a flexible inner tube, a spiral groove formed around the flexible inner tube over an entire length of the bendable part and the flexible tube, at least one coil wound along a bottom of the spiral groove, and at least one type of filler with which the spiral groove is filled. The treatment tool insertion channel includes a first portion that includes a part inside the bendable part and a second portion at a proximal end side of the first portion, the first portion being configured more flexible than the second portion.
US08246533B2
A system for securing an implantable apparatus to a mammal includes a mount including a base portion having a plurality of holes dimensioned to receive rotationally-driven fasteners, each fastener comprising a helical portion having a tip configured for tissue penetration, the mount configured to secure the implantable apparatus relative to tissue of the mammal upon driving the fasteners into the tissue. The system further includes a fastening tool configured to rotationally drive the helical portion of the fasteners into the tissue. The mount may be secured to the fascia covering the sternum via a subcutaneous securement method, or it may be attached to the intra-abdominal wall, behind the sternum, or it may be attached to the sternum directly via bone screws or the like.
US08246532B2
The present invention relates to implantable medical devices for improving sound perception by subjects with conductive or mixed conductive/sensorineural hearing loss. In particular, the present invention provides methods and devices for vibrating the skull of a hearing impaired subject.
US08246527B2
A folding system for folding leading and/or trailing flaps of container blanks is provided. The system may include a conveyor having a conveying surface configured for conveying the blank along a predetermined path to a first folding position and a second folding position, a folding apparatus, and a control system. The folding apparatus may include a drive assembly and a folding tool. The control system may be operatively coupled to the folding apparatus and operable to control movement of the folding tool between a first rotational position and a second rotational position. Rotation of the folding tool to the first rotational position may cause the leading flap of the container blank positioned in the first folding position to fold about a leading flap fold line. Rotation of the folding tool from the first rotational position to the second rotational position may cause the trailing flap of the container blank positioned in the second folding position to fold about a trailing flap fold line.
US08246518B2
The invention is a transmission shifting system for a vehicle, the vehicle having a transmission having a push-pull and rotating member for operating the transmission movable in an H pattern. In detail, the invention includes a first reversible electric motor coupled to the member for moving the member backwards and forwards. A second reversible electric motor is coupled to the member for rotating the member clockwise and counter-clockwise. The second motor coupled to the member by means of a biasing assembly such that a biasing force can be applied to the member when the second motor rotates without the member rotating. A transmission shifter control system is provided for sequencing the operation of the first and second motors so to move the member in the H pattern upon receipt of an actuation signal.
US08246516B2
A method of operating a drive train of a motor vehicle that has at least an automatic transmission and a drive unit. A starting rotational speed is determined for starting the motor vehicle, and a starting process is initiated with the determined starting rotational speed by engaging a starting element, in particular a starting clutch. The starting rotational speed may be individually set by a driver in such a way that, when the automatic transmission is in the neutral position, the engine speed of the drive unit may be determined by the driver by actuating the accelerator pedal, and that once the automatic transmission is shifted from the neutral position to a either a forward gear or a reverse gear, the engine speed of the drive unit, prevailing during the shift of the automatic transmission, is used as the starting rotational speed.
US08246513B2
A method and apparatus for controlling transmission functions in a transmission of a motor vehicle by an electromagnetically actuated control valve. The control valve is controlled by a control device that includes a stored valve characteristic curve to provide a temperature-dependent and a target-current-dependent overlay, so that a symmetrical target value oscillation around a target current value is achieved. The characteristic curve for controlling the control valve is adapted at least partially as a function of a current value and a temperature.
US08246512B2
In a control device for a vehicular power transmitting device, if engine torque TE generated with using a fuel other than a basic fuel by an internal combustion engine (8) connected to a shifting mechanism (10) for power transmitting capability, exceeds torque TES generated with using a basic fuel, a downshift is initiated at a lower accel-opening than that at which the downshift is initiated with using the basic fuel. That is, the shifting is performed at a shift point enabling the suppression of a torque increase in consideration of an increase in engine torque TE generated by the internal combustion engine, thereby preventing rotary elements of the shifting mechanism (10) from reaching high-speed rotations during a transition in downshift. This minimizes a drop in durability of the shifting mechanism (10).
US08246505B2
A planetary type gear unit comprising a planet carrier with a planet bogie plate and at least one planet shaft, whereby on both sides of the bogie plate a planet wheel is mounted on the planet shaft by taper roller bearings, whereby the planet shaft is provided with an axially displaceable piece on each of its extremities forming an abutment which provides an axial support for the inner bearing rings of the taper roller bearings and with a tensioning elements by which the axially displaceable pieces can be displaced to one another for controlling the pre-tensioning on the taper roller bearings.
US08246496B2
A portable sports goal comprising a frame, a first pliable goalpost member, a second pliable goalpost member and a pliable crossbar member. The frame presents net connection points and is configured to support each of the pliable goal members in tension between two net connection points such that the goal apparatus presents a substantially rectangular goal mouth. A frame for use in the goal apparatus. A net for use in the goal apparatus comprising first, second and third edges, and a first pliable goalpost member, a second pliable goalpost member and a pliable crossbar member extending along the first, second and third edge respectively. A method of providing a goal. A portable football goal.
US08246485B2
A golf club shaft has a more attractive appearance than a coating of plating and also achieves a rustproofing effect within the shaft, while avoiding the problem of an increase in weight and processing of effluents associated with plated shafts. The golf club shaft has a shaft body, a covering film formed by chemical treatment of an outside surface and an inside surface of the shaft body, a coating film layer formed by electric painting on the covering film of at least the outside surface; and a pigment layer, in which a polarizing powder is dispersed, which is coated on the coating film layer.
US08246475B2
A boot assembly and constant velocity joint utilizing the boot assembly is provided. The constant velocity joint and boot assembly includes a first shaft, the first shaft having an axle portion extending between a first end and a second end, at least one of the first end and the second end having an enlarged joint portion. It also includes a hollow boot disposed on the first shaft having a joint end and a shaft end, the joint end disposed proximate the enlarged joint portion and the shaft end disposed proximate the axle portion. The constant velocity joint also includes a spacer, the spacer having an inner surface disposed on the axle portion and an outer surface having the shaft end of the boot disposed thereon.
US08246474B2
A Kelly bar arrangement includes an inner bar and at least one outer bar, whereby the inner bar is arranged with respect to the at least one outer bar in an axially movable but rotationally fixed manner, and a spring means which is arranged in a lower area of the inner bar for cushioning an axial movement of the inner bar with respect to the at least one outer bar. In accordance with the invention provision is made for the spring means to be designed as an elastomer spring.
US08246473B2
A universal joint with improved ball lubrication, the improvement wherein each yoke has a ball head at an inward end of the yoke, the centering plate has a tube in which the ball heads of the yokes are slideably received to establish a slideable connection between the ends of the yokes and the centering plate, and the lubricant is supplied from the second passageway to an interior of the tube. A shield substantially encloses the joint in combination with the tractor master shield and has lubrication fitting access holes.
US08246471B2
There is provided a system and method for providing dynamic recap sequences to a player of a video game. There is provided a method for use by a processor to present a recap sequence to a player of a video game, the method comprising storing, in a memory, identification data identifying the player and associated event data relating to the video game played by the player after a first game play, receiving the identification data to identify the player for a second game play, retrieving the event data from the memory, creating a prioritized event list including a number of events from the event data, generating the recap sequence based on the prioritized event list, and presenting the recap sequence to the player prior to the second game play. Creation of the prioritized event list can be customized to suit particular requirements of the video game.
US08246470B2
A video repository unit includes a plurality of disk drives arranged in a redundant array and circuitry to control writing/reading of video programs to/from the redundant array. A wireless transceiver receives video programs and transmits a selected video program to a remote viewer responsive to a request received by the wireless transceiver. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
US08246463B2
According to a game system and a game apparatus of the present invention, when other game apparatus or a group to which a plurality of game apparatuses belong are present in a range where wireless communication by the game apparatus operated by a player is available, the other game apparatus and the makeup of the group are notified to the player. Thus, the player can form a group of desired game apparatuses by determining a group to enter in consideration of the displayed group information, and execute a multiplayer game using wireless communication.
US08246462B1
A Hall-effect system for providing inputs into a processor includes at least one magnet for establishing a magnetic field, a remote sensor unit and a receive station. The magnet is sized and adapted to be worn on a user's finger, while the remote sensor unit is adapted to be worn on a user's thumb. The remote sensor unit includes a Hall-effect sensor that senses changes in the magnetic field due to the motion of the magnet relative to the Hall-effect sensor. The Hall-effect sensor detects the magnetic field changes, and the remote sensor unit generates a sensor output corresponding to the magnetic field changes. The receive station is connected to the processor. The receive station receives the output from the remote sensor unit and converts the sensor output into an input for the processor.
US08246460B2
Provided is a game system executing a game by performing communication between a plurality of hand-held game apparatuses, each having a display section for displaying an image and an operation section, and a stationary game apparatus. In each of the plurality of hand-held game apparatuses, a plurality of directional signs indicative of operations performed by a player using the operation section is displayed on the display section. Operation data indicative of a content of the operation performed by using the operation section is transmitted to the stationary game apparatus. The stationary game apparatus receives the operation data transmitted from each of the plurality of hand-held game apparatuses. The stationary game apparatus obtains, from sound data storage means storing therein a plurality of pieces of sound data, sound data corresponding to the operation data, and at the same time, outputs a sound based on each piece of the obtained sound data.
US08246459B2
Disclosed are a method, an apparatus, and a recording medium for a performance game, and more particularly are a method, an apparatus, and a recording medium for providing a performance game for playing indicators in a plurality of areas while a user moves in corresponding areas.
US08246448B2
Gaming systems, machines and methods are disclosed that provide various player-centric rewards to the casino patrons. The rewards may be provided across multiple games including slots, tables, keno, and any other casino game. The sweepstakes rewards may be used to promote increased play for chosen time periods, locations, and/or individual players. In addition, patrons can earn sweepstakes rewards based upon the amount of coins played at the slot machine, on the slot floor or throughout the entire casino. Furthermore, the patrons can receive a birthday reward, which may be credited to the eligible patrons on or about the patron's birth date. The rewards may be directly credited to the gaming machines using either cashable or non-cashable credits. The system facilitates patrons continuing to accrue rights toward a reward even when playing different gaming machines, or when playing machines having different denominations.
US08246435B2
A method, system, and computer readable storage medium to provide a variation of a blackjack game. The player does not make any strategy decisions as the player must play his or her hand out according to a predetermined strategy. The dealer also players his or her hand out according to a predetermined strategy.
US08246430B1
A chimney cap capable of being secured to a chimney and including a base; an annular collar member for insertion into a chimney, and having an outside circumference smaller than an opening of the chimney so as to be readily received therein; an annular shaped mesh member that is supported about the collar; a top supported over the base; and a plurality of support rods attached to the collar and for the purpose of supporting the annular shaped mesh member. The annular shaped mesh member has discharge openings for air flow and at least one elongated slot through which one of the support rods extends for securing the annular shaped mesh member. The elongated slot in combination with the one support rod enables adjustment of the diameter of the annular shaped mesh member.
US08246429B2
An apparatus (10) for washing eviscerated poultry carcasses (12) has a housing (11), a conveyor (15a) for moving the shackled poultry carcasses through the housing. A guide bar (24) tilts the poultry carcasses (12) from a vertical position for spraying by a first set of nozzles (23). The first set of nozzles (23) delivers a cleaning solution (100) at a sufficient flow rate and line pressure, whereby a portion of the cleaning solution (100) is deflected back out the rear opening (12d) of the poultry carcass (12).
US08246426B1
An animal carcass hair removal machine paddle is provided. The paddle includes a core of alternating layers of woven and non-woven fabrics. The core is pressed together and surrounded by an outer shell pressed onto the core. The layers of fabric are arranged with some shorter than the full length of the core such that one end of the core is thicker than the other end and the layers form a wave-like pattern when the core is pressed. In some embodiments, the weft or warp of the woven fabrics are arranged in special aligned and/or perpendicular arrangements.
US08246424B2
A polishing disc for a tool for the fine machining of optically active surfaces, particularly on spectacle lenses as workpieces, comprises a main body which has a center axis and on which there is fixed an intermediate layer which is softer than the main body and on which a polishing agent carrier rests. The intermediate layer has, with respect to the center axis, a radial inner region of substantially constant axial thickness and an adjoining radial outer region. The latter is formed or is fixed to the main body in a particular way so as to prevent the edge of the polishing disc from being imprinted on the machined surface of the workpiece in the form of very fine, scratch-like microstructures. Also proposed is a simple method which can be used to produce such a polishing disc.
US08246423B2
An elongated liquid polish dispenser which can be longitudinally attached to a hand-held rotary buffer such that a thumb switch to operate the dispenser is placed opposite a trigger on the buffer's handle is described. The dispenser can be firmly attached by a built-in strap to several popular models of professional heavy duty polishers without obscuring vent holes of those models. The thumb switch activates an electric pump which pumps liquid polish through a nozzle and onto a work surface.
US08246420B1
The problem of controlling dust during an operation such as a micro-etching process, associated with a dental appliance in an efficient and economical manner is solved by a unit which is portable and which encloses the appliance during the micro-etching process.
US08246411B2
A manufacturing method for flexible display apparatus includes following steps. A carrier frame is formed on a rigid substrate. A flexible substrate is formed on the carrier substrate, wherein a border of the flexible substrate is supported by the carrier frame. A display unit is formed on the flexible substrate. At least a portion of the flexible substrate is separated from the carrier frame. In the manufacturing method, the flexible substrate and the carrier frame can be easily separated.
US08246404B1
A swim fin system that may be used to propel an individual through water. The swim fin system may include a leg securement device, with an upper and a lower end, effective for detachably securing to at least the lower leg of an individual. A fin may attach longitudinally to the leg securement device where at least a portion of the fin is oblique to the leg securement device. The swim fin system may further include a second securement device, with an ankle end and a toe end, effective for detachably securing to at least the foot and ankle of an individual.
US08246402B2
An outboard motor includes an engine that generates power and a transmission device arranged to change the speed of rotation of the engine and to transmit the rotation to a propeller. The transmission device includes a planetary gear type transmission mechanism arranged to shift to any of a plurality of speed positions, and the planetary gear type transmission mechanism is controlled to shift such that a sun gear and planetary gears unitarily rotate when a speed position is a normally used speed position. The outboard motor achieves a reduction in load normally caused by engagements between gears in a normally used speed position and also achieves significant improvement in durability of the gears.
US08246398B2
In an outboard marine motor including an upper case (4) enclosing an engine (E) and a lower case (5) fitted with a propeller (12) and connected to a lower end of the upper case, the lower case is configured to be turned relative to the upper case around a vertical axial line. The power of the engine is transmitted to the propeller via a vertical drive shaft (10) which is coaxial with the vertical axial line. Thereby, the outboard marine motor can be steered simply by turning the lower case. Because the upper case having a relatively large lateral dimension as compared with the lower case is not required to be turned, a large steering angle can be achieved without the outboard marine motor interfering with watercraft having the outboard marine motor mounted thereon. This is particularly beneficial when two or more outboard marine motors are used one next to the other.
US08246394B2
A plurality of recesses are formed on a surface of a wire barrel where an electric wire is provided. In a state before the electric wire is crimped onto the wire, barrel, at least one of sides comprising rims of an opening of each recess of a quadrangular shape is a crossing side crossing at an angle of from 85 degrees to 95 degrees to an extending direction. In a state before the electric wire is crimped onto the wire barrel 16, the crossing sides of a plurality of recesses positioned adjacent to each other in the extending direction are so arranged as to overlap with each other in the extending direction.
US08246383B2
A portable electronic device may have a sealed connector secured within a device housing. The sealed connector may have a metal shell. A plastic contact housing may be insert molded within the shell. Conductive signal contacts may be laterally spaced in the contact housing. An elastomeric gasket may be assembled or compression molded onto the metal shell. Left and right metal brackets may be welded onto the metal shell to moisture-seal latch windows. A water-resistant sealing layer may be attached to the bottom plate of the metal shell to moisture-seal alignment rail windows. The sealed connector may be pressed against the device housing to place the gasket in a compressed state. The connector may be secured to the device housing by screwing down the metal brackets to a circuit board assembled within the housing while the gasket is in the compressed state.
US08246382B1
A bendable patch panel structure installed on a chassis includes a patch panel and a fixing element. The patch panel includes a first panel, a second panel, a hinge pivotally coupled between ends of the first and second panels, and a connecting plate separately installed at other ends of the first panel and second panel and pivotally coupled to the chassis. After the first and second panels are bent and adjusted, a fixing element for the appropriate connection is selected according to the shape of the two unfolded metal plates of the hinge, such that the installer can adjust the bending condition of the patch panel in a time-saving, effort-saving, quick and easy manner.
US08246376B2
The flexible electrical connector is designed to facilitate electrical connections between a power receiving device, such as an at least partially electric vehicle, and a power supplying device, such as an electric vehicle charging station. The flexible electrical connector has a blade shaped housing attached to a power cord that extends to the power supplying device. The blade shaped housing has a substantially rigid end portion with an electrical interface configured to detachably mate with a corresponding electrical interface on the power receiving device. The blade shaped housing also has a handle portion made of a substantially flexible material such which is configured to flex about the rigid end portion along an arc in a single plane. As such, the flexible handle can absorb impacts it receives rather than transferring them to the rigid and breakable electrical interface components.
US08246371B2
A standoff for providing a fluid-tight seal for an electrical connection in a well between an electrical conductor extending from down hole of the well and a power source conductor extending from an above-ground power source is enclosed by and extends through and further into the wellbore. The power source conductor extends down hole to a connector for connecting the power source conductor to the electrical conductor. The standoff includes a rigid tube adapted to extend through a wellhead barrier of the well and terminate at a lower end. A rubber boot surrounds the rigid tube. An electrical insulative tubular body has a hole forming a first inner surface surrounding the power source cable between the lower end of the rigid tube and the connector, the rubber boot surrounding the tubular body. A sleeve is placed at one end of the tubular body and has a second, larger hole coaxial with the first hole and forming a second inner surface. An internal surface is formed between the first and second inner surfaces, the lip surrounding a portion of the rigid tube adjacent the lower end and the internal shoulder engages the lower end of the rigid tube for preventing the rubber boot from extruding between the tubular body and the rigid tube when pressurized and evenly distributing the compressive force on the end of the standoff. On the other end of the standoff, a washer sits atop the electrical connector and supports the insulation.
US08246350B2
A safety attachment for application to orthodontic wire in the mouth of a patient comprises a safe-end portion to be crimped onto the orthodontic wire, which once in place on the wire has no sharp edges. The safety attachment comprises upper and lower portions secured to each other by a hinge. One or both of the inner surfaces of the attachment may be textured to improve grip on the wire. The safety attachment may include means for retention by application pliers. Pliers designed for application of a safety attachment have upper and lower beaks, wherein the upper beak includes means to crimp the safe-end portion onto an orthodontic wire and the lower beak includes means to retain the safety attachment prior to applying the safe-end portion to the wire and after application release the safe-end portion leaving it in place on the wire in the patient's mouth.
US08246348B2
A self-ligating orthodontic bracket with a replaceable closing spring member detachably connected to the upper structure of a tooth-attachable base member. Particular preferred embodiments relate to the form of detachable connection of the closing spring member with the upper structure, with one particularly preferred embodiment being torsion tabs that are reversibly deformable to maintain pivoting engagement of spring member and upper structure when desired and easy removal of the spring members when desired.
US08246343B2
In one embodiment, a method for generating heat energy includes injecting a stream having a concentration of at least 50% oxygen (O2 stream) into a primary gas stream through a mixer, the mixer discharging the O2 stream as two or more spaced jets traversing the primary stream, thereby enriching the primary gas stream. The method further includes mixing fuel with the enriched primary gas stream, thereby forming a fuel stream; and combusting the fuel stream, thereby forming a flue gas stream.
US08246340B2
A injection molding die includes a first molding unit, a second molding unit, at least one slide block, and a number of elastic elements disposed between the slide block and the first molding unit. The first molding unit includes a first molding surface and a sidewall surrounded the first molding surface. At least one gap is defined in an edge between the sidewall and the first molding surface. The gas hole is exposed at the gap for providing gas to the gap. The slide block is capable of moving toward or away from the sidewall, and includes a protrusion for engaging in the gap to cover the gas hole. The protrusion includes a protrusion surface coplanar with the first molding surface. The second molding unit includes a second mold surface defining a mold cavity cooperated with the first molding surface, the protrusion surface, and the at least one slide block.
US08246339B2
The present invention relates to a door skin comprising an exterior surface having outer portions lying on a first plane, spaced grooves recessed from the plane of the outer portions, and tonal portions having a planar area and a plurality of spaced depressions recessed from the plane of said planar area. The present invention is also directed to a method of etching a plate, for use with a molded die set, for embossing a wood grain pattern in the door skin, and the etched plate formed therefrom.
US08246338B2
A device and process for conditioning plastic preforms (5) comprising a cooling turret (6) featuring faces fitted with many holders (7) for conditioning preforms (5). This turret rotates around a horizontal axis (X) and carries out a vertical traverse between a top position under an arm (3), which unloads the preforms from the mould, and a bottom position near the table for extracting the preforms (5) from the turret (6). Tie structure of the turret consists of two parallel bars (18, 19) and several joining plates (14) to which the bases of the holders (7) are attached.
US08246335B2
An apparatus for molding optical fiber connector is provided. The optical fiber connector includes a main body. The main body has a blind hole for receiving an optical fiber two opposite surfaces being substantially parallel with the blind hole, and a lens portion aligned with the blind hole. The apparatus comprises a molding cavity and an insert for forming the blind hole. The molding cavity includes a central portion for forming the main body, a lens-forming portion for forming the lens portion, and two lateral portions for forming the corresponding surfaces. The molding cavity includes a first gate and a second gate for introducing molding material into the molding cavity. The first gate is located between the insert and one of the two lateral portions and the second gate is defined between the insert and the other one of the lateral potions.
US08246326B2
A seal section for use in a downhole submersible pumping system includes a housing, a bag support tube extending through the housing, a shaft positioned inside the bag support tube and a bag plate connected to the bag support tube. The bag plate preferably includes an end cap secured to the bag support tube and a locking collar threadingly engaged with the end cap. The bag plate is configured to receive the open end of a cylindrical seal bag manufactured from perflouroalkoxy polymer. The end cap includes a tapered head that tapers from a first diameter that is slightly larger than the inner diameter of the seal bag to a second diameter that is slightly smaller than the inner diameter of the seal bag. This mechanism for securing the seal bag obviates the need for o-ring or other mechanical seals between the seal bag and the bag plate.
US08246317B2
A fan assembly for creating an air current includes a base having an air inlet and an air outlet, the base housing an impeller and a motor for rotating the impeller to create an air flow passing from the air inlet to the air outlet. The fan assembly further includes a vertically oriented, elongate annular nozzle including an interior passage having an air inlet for receiving the air flow from the base and a mouth for emitting the air flow, the nozzle defining an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth.
US08246313B2
A dynamic port that extends from the bottom wall of an oil reservoir that surrounds the lower guide bearing of a reactor coolant pump and is in fluid communication within an oil level gauge. The dynamic port is rotatable into and out of the oil flow path to adjust the dynamic oil level shown by the oil level gauge when the pump is at operating speed to be substantially equal to the static oil level when the motor is at rest.
US08246312B2
A hub assembly for use with a wind turbine is provided. The hub assembly includes a body formed from a first material, a bearing seat formed integrally with the body, and a support assembly positioned within an opening defined by the bearing seat and at least partially coupled to the body. The support assembly includes an insert formed from a second material different than the first material.
US08246309B2
A rotor disk for a fan in a turbomachine is disclosed. The disk includes in its perimeter a plurality of essentially axial grooves for the installation and retention of vane roots having hooks at their downstream ends, and deformable regions formed by cavities being situated at the downstream end of the grooves in attachment flanges for inter-vane platforms to absorb the stresses between the disk and the vane roots.
US08246307B2
A blade for a rotor, such as a turbine rotor of a gas turbine engine, has a squealer tip comprising a peripheral wall which defines a cavity. A first region of the peripheral wall extends radially, with its outer surface forming a continuation of the adjacent aerofoil surface of the blade. A second region extends obliquely with respect to the radial direction and the adjacent part of the aerofoil surface. The second region defines a winglet, and serves to increase the width of the chamber towards the trailing edge of the blade.
US08246304B2
A method of determining at least one rotation parameter of a wind turbine rotor rotating with a rotation speed and a phase is provided. The method includes: measuring an effective centrifugal force acting in a first pre-determined direction, which is defined in a co-ordinate system rotating synchronously with the rotor, on at least one reference object located in or at the rotor, establishing a first angular frequency representing the rotation speed of the rotor on the basis of variations in the measured effective centrifugal force due to gravitational force, establishing a second angular frequency representing the rotation speed of the rotor by use of at least one yaw rate gyro, and establishing the value of the rotation speed as the rotational parameter by correcting the second angular frequency by comparing it to the first angular frequency.
US08246301B2
A fan assembly includes a side panel, a mounting panel and a fan module. The side panel defines a vent. The mounting panel is perpendicularly attached to the side panel. A retaining opening is defined in the mounting pane. The fan module includes a fan and a retaining member. The fan is configured for generating airflow towards the vent. The retaining member is attached to the fan module. The retaining member includes a body and an arm. The body includes a resilient portion. A protrusion protrudes from the resilient portion corresponding to the retaining opening. The arm is connected to the resilient portion. The arm is capable of being actuated to pull the resilient portion to deform away from the mounting panel to disengage the protrusion from the retaining opening.
US08246299B2
A ceramic seal segment for a shroud ring of a rotor of a gas turbine engine, the ceramic seal segment positioned radially adjacent the rotor and characterized by being a hollow section that defines an inlet and an outlet for the passage of coolant therethrough.
US08246296B2
In one embodiment, a centrifugal impeller is described having a front side with airfoils and a back side. A conduit may be formed between the front side and the back side, or any other side, and may convey pressurized working fluid between the two. The conduit may pass relatively high pressure working fluid between any two locations such as from the front side to the back side. The conduit may include an aperture located on the front side and an aperture located on the back side. Any number of conduits may be defined within the centrifugal impeller. Apertures located on the front side of the impeller may be formed in any suitable place, such as a hub of the impeller or an airfoil surface, to set forth just two non-limiting examples.
US08246290B2
A carton feeder assembly is disclosed for selecting or picking carton blanks from the end of a stack of blanks in a magazine. The assembly includes a magazine and conveyor for moving stacks of carton blanks toward a carton feeder assembly. A support shaft assembly is disposed at the downstream end of the magazine and includes a support shaft against which the forwardmost carton blank in the stack leans and rests to support the stack of carton blanks. The support shaft is eccentrically rotatably mounted and driven by a motor so that the support shaft oscillates rapidly as it is rotated. This motion of the support shaft keeps the forwardmost blank of the stack spaced slightly from and out of contact with the support shaft for a significant majority of the time, thus reducing substantially the average friction between the forwardmost blank and the support shaft. Thus, the forwardmost blank can gripped with suction cups of the feeder assembly, which can then be moved to slide the forwardmost blank from beneath the support shaft and off of the stack of blanks with very little frictional resistance. The suction cups thus stay attached to the blank and do not tend to slide off due to shear forces developed in overcoming frictional resistance.
US08246277B2
A tool holder for clamping an insert holder has a main block, two clamping members and a single adjustment member. The main block has a longitudinal side surface with a longitudinal groove with upper and lower walls. The two clamping members include mirror symmetrical left and right clamping members interfacing with two inclined non-parallel planar ramping surfaces of the lower wall of the longitudinal groove. A blade-shaped insert holder is mounted in the longitudinal groove on the two clamping members. The adjustment member interfaces with the two clamping members, and when rotated causes each clamping member to move up its respective non-parallel planar ramping surface, decreasing the distance between the two clamping members and the upper wall of the longitudinal groove until a clamping force is uniformly applied between the insert holder and the upper wall of the longitudinal groove.
US08246276B2
A pumpable inflatable crib bag assembly for supporting a mine roof which includes a generally cylindrical bag having top and bottom ends for retaining and confining a liquid settable grout to be pumped into the bag. The bag further includes an inner generally cylindrical mesh reinforcement disposed within and generally coextending with the bag. This generally cylindrical mesh reinforcement is spaced from an inner wall of the bag and is permeable to the liquid settable grout whereby the liquid settable grout may be pumped through a fill port into the bag to thereby fill the bag and encapsulate the mesh reinforcement. The liquid settable grout is pumped through a fill port which is adjacent the top end of the bag.
US08246272B1
An actuated spill barrier, comprises a chassis having a first pier and a second pier, a sump disposed within the chassis, the sump structure having a first angled wall at a first side and a second angled wall at an opposite second side, a door pivotally connected to the first pier and the second pier, the door having an angled first end surface and an angled second end surface, the first angled wall and the angled first end surface being supplementary angles and the second angled wall and the angled second end surface being supplementary angles inhibiting binding of the door, wherein thermal expansion of the door causes the first end surface to climb upwardly along said first angled wall and said second end surface to climb upwardly along said second angled wall inhibiting binding of said door in said sump, the door being biased to pivot from a first actuated position to a second position sealing against the first pier and the second pier.
US08246271B2
An apparatus for compacting road shoulders is provided comprising a primary carriage adapted to be mounted to a vehicle, an attachment carriage adjustably mounted to the primary carriage, a compacting attachment adjustably mounted to the attachment carriage, a control system in communication with at least one actuator, and a vibrator disposed on the apparatus. The apparatus for compacting road shoulders able to be positioned within a normal width of a vehicle, vibrationally compact the road shoulder, and adjust according to a grade of the shoulder.