US08330349B2
The present invention is directed to phosphors and white light emitting diodes and a method for preparing a Ce3+ doped calcium silicate phosphor represented by a chemical formula of (Ca1-yMy)2-x-zSiO4:Ce3+x,N+z, wherein x is 0
US08330348B2
An apparatus device such as a light source is disclosed which has an OLED device and a structured luminescence conversion layer deposited on the substrate or transparent electrode of said OLED device and on the exterior of said OLED device. The structured luminescence conversion layer contains regions such as color-changing and non-color-changing regions with particular shapes arranged in a particular pattern.
US08330343B2
A plasma display device includes a plasma display panel, a chassis disposed on the plasma display panel with a heat-conducting sheet in between, a small-signal processing circuit board disposed on a rear face of the chassis, a thermal sensor, a thermal sensor fixture for installing the thermal sensor, a front frame, and a back cover having a ventilation area with multiple ventilating holes. The thermal sensor fixture has a shielding wall around the thermal sensor and is disposed on a rear face of the small-signal processing circuit board. The thermal sensor is disposed at an intermediate position between the plasma display panel and the back cover at a position facing the back cover.
US08330337B2
An LED lamp includes a light source including LEDs and a heat dissipation device. The heat dissipation device includes a heat absorption board contacting the light source to absorb heat generated by the LEDs, a fin assembly located over the heat absorption board, two heat pipes thermally connecting the heat absorption board and the fin assembly, a fan and a fan holder fixing the fan on the fin assembly. The fan holder includes a supporting board supporting the fan and supporting posts connecting an outer edge of the heat dissipation board and an outer edge of the supporting board. The supporting posts are embedded in the fin assembly.
US08330326B2
A piezoelectric motor that includes a rotor and a stator having a surface on which a driving member that is in contact with the rotor for rotating the rotor is disposed. The stator includes a stator body, a plurality of piezoelectric elements disposed on a surface of the stator body, and an electrode wiring plate integrally formed with the stator body. The piezoelectric elements are electrically connected to a plurality of electrodes formed on the electrode wiring plate through a plurality of wiring lines. The wiring lines are constituted by an electroconductive film extending from a surface of the stator body to the electrodes.
US08330324B2
An apparatus, system and method for controlling drive patterns is disclosed. A digital engine for controlling drive patterns may include a profile controller to program characteristics of one or more drive patterns for one or more piezoelectric actuators. The digital engine may further include a register array to store profile information for the one or more drive patterns. Each drive pattern may comprise a plurality of pulses with each pulse having a slope. The digital engine may also include a digital pattern generator to generate the one or more drive patterns based upon the profile information stored in the register array. The digital engine may further include a slope shaping circuit to modify one or more signals based upon an input from the digital pattern generator.
US08330323B2
A source signal is converted into a time-variant temperature field with transduction into mechanical motion. In one embodiment, the conversion of a source signal into the time-variant temperature field is provided by utilizing a micro-fabricated fast response, bolometer-type radio frequency power meter. A resonant-type micromechanical thermal actuator may be utilized for temperature read-out and demodulation.
US08330322B2
The present invention provides an actuator which suppresses the inflow of water and the like, and is unlikely to cause cracking and peeling even when repeatedly driven. An actuator having a conductive layer and an ion-conducting layer includes: a first layer which is provided in contact with the actuator and is formed from a polymer that suppresses the permeation of water; and a second layer which is provided in contact with the first layer, has a lower tensile elastic modulus than that of the first layer, protects the first layer, and is formed from a polymer. The first layer and the second layer can cover the whole actuator.
US08330318B2
A rotating electrical machine includes: a stator that has a stator core and a stator coil; and a rotor disposed rotatably on an inner circumferential side of the stator core. The stator core includes a plurality of slots opening on the inner circumferential side and the slots are each formed as an open slot with a width of an inner circumferential-side opening thereof ranging along a circumferential direction set substantially equal to or greater than a width of a bottom side measured along the circumferential direction. The stator further includes a slot insulator disposed between inner wall of each of the slots at the stator core and the stator coil and a holding member constituted with a nonmagnetic material and inserted in each of the slots at the stator core so as to hold the slot insulator between two side surfaces present along the circumferential direction at the slot. The stator is formed by winding the stator coil through the plurality of slots.
US08330316B2
Various embodiments relate generally to electrodynamic machines and the like, and more particularly, to rotor assemblies and rotor-stator structures for electrodynamic machines, including, but not limited to, outer rotor assemblies. In some embodiments, a stator assembly including field pole members arranged about an axis of rotation and including pole faces at the ends of the field pole members, subsets of the pole faces being disposed within a boundaries of conically-shaped spaces having apexes disposed on the axis of rotation. The rotor assemblies include interior regions in which the subsets of the pole faces are disposed, the interior regions having surfaces external to the boundaries of the conically-shaped spaces. The rotor assemblies also include subsets of magnets interleaved circumferentially with the subsets of magnetically permeable structures and boost magnets disposed adjacent the subsets of magnetically permeable structures. Further, rotor assemblies include flux conductor shields disposed adjacent the boost magnets.
US08330306B2
A magneto-plasma-dynamic (MPD) generator, comprising: a conveying duct shaped for conveying a high velocity, conductive fluid; a magnetic field generator arranged to generate a magnetic field across the conveying duct, substantially perpendicular to the direction of travel of the fluid, such that the fluid passes through the magnetic field (2) when conveyed by the duct; electrodes provided in the conveying duct to conduct a current induced in the fluid as it is conveyed by the conveying duct through the magnetic field; and an electrode supplying mechanism configured to supply a conductive liquid for replenishing the electrodes.
US08330305B2
A system and method for protecting devices from impact damage is provided. Prior to impact between a surface and a device, a determination of a risk of damage to the device is made. If the risk of damage to the device exceeds a threshold, a protection system is activated to reduce or substantially eliminate damage to the device.
US08330297B2
There is provided a system for supplying power to a site having a load. The system comprises a number n of power source units, the value of n being greater than or equal to 3. The system further comprises a number t≦tmax of loads groups, each load group having a number i of inputs. The value of i is greater than or equal to 2 and less than the value of n. Each load group receives power from i power source units, such that each load group is connected to a unique combination of i power source units. tmax is such that every possible combination of i power source units is connected to a unique load group.
US08330287B2
A device (1) making it possible to convert the undulation and/or the oscillations of a liquid in which it is at least partially immersed into usable energy. The device (1) includes a float (3) guided by a guide device (2) anchored in the sea bed, with the aid of guide element (12) and including conversion element making it possible to convert the relative movements between the float (3) and the guide device (2) into usable energy such as electric energy.
US08330280B1
A bump structure comprises a first polymer block, a second polymer block, a first groove, an under bump metallurgy layer and a connection metal layer, wherein the first polymer block and the second polymer block are individual blocks. The first polymer block and the second polymer block are located at two sides of the first groove, the first polymer block comprises a first connection slot, and the second polymer block comprises a second connection slot communicated with the first connection slot and the first groove. The under bump metallurgy layer covers the first polymer block and the second polymer block to form a second groove, a third connection slot and a fourth connection slot communicated with each other. The connection metal layer covers the under bump metallurgy layer to form a third groove, a fifth connection slot and a sixth connection slot communicated with each other.
US08330279B2
A semiconductor device includes a supporting board having a protection film thereon; a semiconductor chip provided on the supporting board; a first internal connecting terminal formed on the supporting board; a second internal connecting terminal formed on the semiconductor chip; a first insulation layer for covering an upper surface of the supporting board and upper and lateral surfaces of the semiconductor chip; a wiring pattern provided on the first insulation layer, the wiring pattern connecting the first and second internal connecting terminals; a solder resist layer provided on the first insulation layer and the wiring pattern, the solder resist layer having an opening part; an external connecting terminal provided so as to connect to the wiring pattern through the opening part; a groove part formed on outer peripheries of the supporting board, the protection film, and the first insulation layer; and a resin layer formed in the groove part.
US08330277B2
A semiconductor element built-in device includes: a first substrate having a first pad thereon; a semiconductor element on the first substrate; a second substrate having a second pad thereon and mounted on the first substrate via a solder terminal having a solder coated thereon; a resin layer provided between the first substrate and the second substrate such that the solder terminal and the semiconductor element are embedded in the resin layer; and a dam provided at least partially around at least one of the first and second pads, the dam being configured to restrain the solder flowing from the solder terminal.
US08330271B2
A semiconductor element that is excellent in both mechanical reliability and electrical reliability and a mounting structure for the semiconductor element are provided.The semiconductor element includes: a substrate; an electrically conductive layer on the substrate; a protective layer having an opening on the electrically conductive layer; a barrier metal layer in contact with the electrically conductive layer in the opening; and an electrically conductive bump on the barrier metal layer. The barrier metal layer contains phosphorus and has a phosphorus-rich portion that has a higher phosphorus content than the remaining portion has. The phosphorus-rich portion is located in the surface of the barrier metal layer facing the electrically conductive bump, and the thickness thereof in the periphery of the region where the electrically conductive bump is formed is larger than at the center of the region.
US08330252B2
An integrated circuit device includes a semiconductor chip and a control chip at different supply potentials. A lead chip island includes an electrically conductive partial region and an insulation layer. The semiconductor chip is arranged on the electrically conductive partial region of the lead chip island and the control chip is cohesively fixed on the insulation layer.
US08330250B2
A vertically oriented p-i-n diode is provided that includes semiconductor material crystallized adjacent a silicide, germanide, or silicide-germanide layer, and a dielectric material arranged electrically in series with the diode. The dielectric material has a dielectric constant greater than 8, and is adjacent a first metallic layer and a second metallic layer. Numerous other aspects are provided.
US08330248B2
A semiconductor device includes a circuit portion including at least one real feature, and a plurality of dummy feature groups each including a plurality of dummy features spaced apart from each other by a first distance. The plurality of dummy feature groups are spaced apart from each other by a second distance larger than the first distance, and the circuit portion and the plurality of dummy feature groups are spaced apart from each other by the second distance.
US08330247B2
The invention relates to a semiconductor arrangement and method for production thereof, wherein the semiconductor arrangement is provided with an integrated circuit arranged on a substrate. The integrated circuit is structured on the front face of the substrate and at least one capacitor is connected to the integrated circuit, wherein the at least one capacitor is designed as a monolithic deep structure in trenches. The trenches are arranged in at least one first group and at least one second group, the trenches of a group running essentially parallel to each other and the first and second group are at an angle to each other, essentially at right angles to each other.
US08330240B2
A multi-state current-switching magnetic memory element has a magnetic tunneling junction (MTJ), for storing more than one bit of information. The MTJ includes a fixed layer, a barrier layer, and a non-uniform free layer. In one embodiment, having 2 bits per cell, when one of four different levels of current is applied to the memory element, the applied current causes the non-uniform free layer of the MTJ to switch to one of four different magnetic states. The broad switching current distribution of the MTJ is a result of the broad grain size distribution of the non-uniform free layer.
US08330238B2
A method of packaging a micro electro-mechanical structure comprises forming said structure on a substrate; depositing a sacrificial layer over said structure; patterning the sacrificial layer; depositing a SIPOS (semi-insulating polycrystalline silicon) layer over the patterned sacrificial layer; treating the SIPOS layer with an etchant to convert the SIPOS layer into a porous SIPOS layer, removing the patterned sacrificial layer through the porous layer SIPOS to form a cavity including said structure; and sealing the porous SIPOS layer. A device including such a packaged micro electro-mechanical structure is also disclosed.
US08330230B2
A semiconductor device pad is configured to have the same voltage level as that of a semiconductor substrate. The pad includes a semiconductor substrate having a junction area doped with a high concentration of impurity ions, a polylayer portion at least a portion of which is electrically connected to the junction area and a metal layer portion electrically connected to the polylayer portion and receiving a voltage externally applied. The metal layer is configured to transfer the received voltage to the semiconductor substrate.
US08330228B2
A Ge and Si hybrid material inversion mode GAA (Gate-All-Around) CMOSFET includes a PMOS region having a first channel, an NMOS region having a second channel and a gate region. The first channel and the second channel have a circular-shaped cross section and are formed of n-type Ge and p-type Si, respectively; the surfaces of the first channel and the second channel are substantially surrounded by the gate region; a buried oxide layer is disposed between the PMOS region and the NMOS region and between the PMOS or NMOS region and the Si substrate to isolate them from one another. In an inversion mode, current flows through the overall cylindrical channel, so as to achieve high carrier mobility, reduce low-frequency noises, prevent polysilicon gate depletion and short channel effects and increase the threshold voltage of the device.
US08330225B2
NMOS transistors having controlled channel strain and junction resistance and methods for the fabrication of same are provided herein. In some embodiments, an NMOS transistor may include a transistor stack comprising a gate dielectric and a gate electrode formed atop a p-type silicon region; and a source/drain region disposed on both sides of the transistor stack and defining a channel region therebetween and beneath the transistor stack, the source drain region including a first silicon layer having a lattice adjusting element and one or more second silicon layers having a lattice adjusting element and an n-type dopant disposed atop the first silicon layer.
US08330207B2
A flash memory device including a lower tunnel insulation layer on a substrate, an upper tunnel insulation layer on the lower tunnel insulation layer, and a P-type gate on the upper tunnel insulation layer, wherein the upper tunnel insulation layer includes an amorphous oxide layer.
US08330201B2
There is provided a non-volatile semiconductor memory having a charge accumulation layer of a configuration where a metal oxide with a dielectric constant sufficiently higher than a silicon nitride, e.g., a Ti oxide, a Zr oxide, or a Hf oxide, is used as a base material and an appropriate amount of a high-valence substance whose valence is increased two levels or more (a VI-valence) is added to produce a trap level that enables entrance and exit of electrons with respect to the base material.
US08330200B2
A semiconductor device includes a P-body layer formed in an N-epitaxial layer; a gate electrode formed in a trench in the P-body and N-epitaxial layer; a top source region formed from the P-body layer next to the gate electrode; a gate insulator disposed along a sidewall of the gate electrode between the gate electrode and the source, between the gate electrode and the P-body and between the gate electrode and the N-epitaxial layer; a cap insulator disposed on top of the gate electrode; and an N+ doped spacer disposed along a sidewall of the source and a sidewall of the gate insulator. The source includes N+ dopants diffused from the spacer. A body contact region containing P-type dopants is formed from the N-epitaxial layer. The contact region touches one or more P-doped regions of the P-body layer and the source. Methods for manufacturing such a device are also disclosed. Embodiments of this invention may also be applied to P-channel devices.
US08330196B2
A semiconductor device according to an embodiment includes: a semiconductor layer; source and drain regions in the semiconductor layer; a magnetic metal semiconductor compound film on each of the source and drain regions, the magnetic metal semiconductor compound film including the same semiconductor as a semiconductor of the semiconductor layer and a magnetic metal; a gate insulating film on the semiconductor layer between the source region and the drain region; a gate electrode on the gate insulating film; a gate sidewall formed at a side portion of the gate electrode, the gate sidewall being made of an insulating material; a film stack formed on the magnetic metal semiconductor compound film on each of the source and drain regions, the film stack including a magnetic layer; and an oxide layer formed on the gate sidewall, the oxide layer containing the same element as an element in the film stack.
US08330190B2
A semiconductor device includes a first metal layer disposed on a semiconductor substrate; an insulating layer disposed on the first metal layer; and a second metal layer disposed on the insulating layer and having an electrode pad surface exposed to the outside, wherein a recess is disposed in the insulating layer and the second metal layer; and at least the second metal layer is disposed in the recess of the insulating layer.
US08330189B2
A one time programmable nonvolatile memory formed from metal-insulator-semiconductor cells. The cells are at the crosspoints of conductive gate lines and intersecting doped semiconductor lines formed in a semiconductor substrate.
US08330187B2
A GaN-based field effect transistor (MOSFET) is comprised of a channel layer comprised of p-type GaN, an electron supply layer, a surface layer having band gap energy smaller than that of the electron supply layer, sequentially laminated on a substrate, and recess section is formed by removing a part of the drift layer, the electron supply layer, and the surface layer down to a depth that reaches to the channel layer. A source electrode and a drain electrode are formed so that the recess section positions between them, a gate insulation film is formed on the surface layer and on inner-surface of the recess section including the channel layer, and a gate electrode is formed on the gate insulating film in the recess section.
US08330184B2
In one embodiment, a bidirectional voltage-regulator diode includes first to fifth semiconductor layers formed on an inner surface of a first recess formed in a semiconductor substrate of an N-type in the order. The first semiconductor layer of the N-type has a first impurity concentration lower than an impurity concentration of the semiconductor substrate. The second semiconductor layer of a P-type has a second impurity concentration. The third semiconductor layer of the P-type has a third impurity concentration higher than the second impurity concentration. The fourth semiconductor layer of the P-type has a fourth impurity concentration lower than the third impurity concentration. The fifth semiconductor layer of the N-type has a fifth impurity concentration.
US08330182B2
The light emitting device has a light emitting element 101, and translucent material 102 that passes incident light from the light emitting element 101 and emits that light to the outside. The sides of the translucent material 102 perimeter are inclined surfaces 107 that become wider from the upper surface to the lower surface. The area of the lower surface of the translucent material 102 is formed larger than the area of the upper surface of the light emitting element 101. The lower surface of the translucent material 102 and the upper surface of the light emitting element 101 are joined together, and the part of the lower surface of the translucent material 102 that is not joined with the light emitting element 101 and the inclined surfaces 101 are covered by light reflecting resin 103.
US08330181B2
A semiconductor light-emitting device capable of increasing an amount of light irradiated to the outside is provided.A semiconductor light-emitting device (1) includes a substrate (2), an n-type semiconductor layer (3), a light-emitting layer (4), a p-type semiconductor layer (5), an n-side pad electrode (6), an n-side pad electrode (7), a p-side electrode (8), a reflecting layer (9), and a p-side pad electrode (10). The n-side pad electrode (7) is electrically connected to the n-type semiconductor layer (3) via the n-side pad electrode (6). The p-side pad electrode (10) is electrically connected to the p-type semiconductor layer (5) via the p-side electrode (8). A connection surface (7a) of the n-side pad electrode (7) connected to the n-type semiconductor layer (3) is arranged in a first area (Ar1) closer to a short side (2b) on an arrow B direction-side, and a connection surface (10a) of the p-side pad electrode (10) connected to the p-type semiconductor layer (5) is arranged in a fourth area (Ar4) closest to a short side (2b) on an arrow A direction-side among the first area (Ar1) to the fourth area (Ar4) formed by equally dividing the substrate (2) into four.
US08330172B2
An organic light emitting diode display capable of reducing the shortening of image stacking lifetime caused by the residue of the barrier ribs produced during the forming of the barrier ribs is provided. The display includes: a substrate; a first pixel electrode formed on the substrate; barrier ribs formed on the substrate, and having an opening exposing the first pixel electrode; a second pixel electrode formed on the first pixel electrode; an organic light emitting member formed on the second pixel electrode; an organic light emitting member formed on the second pixel electrode; a common electrode formed on the organic light emitting member; and a thin film encapsulation member covering the common electrode. The width of the second pixel electrode is greater than the exposure width of the first pixel electrode exposed through the opening of the barrier ribs.
US08330156B2
In a thin film transistor including an oxide semiconductor, an oxide cluster having higher electrical conductance than the oxide semiconductor layer is formed between the oxide semiconductor layer and a gate insulating layer, whereby field effect mobility of the thin film transistor can be increased and increase of off current can be suppressed.
US08330155B2
Semiconductor devices include a gate electrode, a gate insulation layer, a first channel layer pattern, a second channel layer pattern and first and second metallic patterns. The gate electrode is on a substrate. The gate insulation layer is on the gate electrode. The first channel layer pattern is on the gate insulation layer, and has a first conductivity level. The second channel layer pattern is on the first channel layer pattern, and has a second conductivity level that is lower than the first conductivity level. The first and second metallic patterns are on the gate insulation layer and contact respective sidewalls of the first and second channel layer patterns.
US08330151B2
The organic electroluminescent element of the present invention includes at least a pair of electrodes, at least one organic light-emitting layer between the pair of electrodes, and at least one lens A on a light-extracting surface of the pair of electrodes, wherein one of the pair of electrodes is a reflective electrode, and the other is a semi-transmissive/semi-reflective electrode, and wherein a real part n1 of a refractive index of the organic light-emitting layer and a real part n2 of a refractive index of the lens A satisfy the relationship n1>n2, and the real part n2 is represented by Expression (1) described below: n2≦n3 sin θ2 Expression (1).
US08330150B2
An organic light-emitting display device, which may be configured to prevent moisture or oxygen from penetrating the organic light-emitting display device from the outside is disclosed. An organic light-emitting display device, which is easily applied to a large display device and/or may be easily mass produced is further disclosed. Additionally disclosed is a method of manufacturing an organic light-emitting display device. An organic light-emitting display device may include, for example, a thin-film transistor (TFT) including a gate electrode, an active layer insulated from the gate electrode, source and drain electrodes insulated from the gate electrode and contacting the active layer and an insulating layer disposed between the source and drain electrodes and the active layer; and an organic light-emitting diode electrically connected to the TFT. The insulating layer may include, for example, a first insulating layer contacting the active layer; and a second insulating layer formed of a metal oxide and disposed on the first insulating layer.
US08330141B2
A light-emitting device includes an n-type silicon thin film (2), a silicon thin film (3), and a p-type silicon thin film (4). The silicon thin film (3) is formed on the n-type silicon thin film (2) and the p-type silicon thin film (4) is formed on the silicon thin film (3). The n-type silicon thin film (2), the silicon thin film (3), and the p-type silicon thin film (4) form a pin junction. The n-type silicon thin film (2) includes a plurality of quantum dots (21) composed of n-type Si. The silicon thin film (3) includes a plurality of quantum dots (31) composed of p-type Si. The p-type silicon thin film (4) includes a plurality of quantum dots (41) composed of p-type Si. Electrons are injected from the n-type silicon thin film (2) side and holes are injected from the p-type silicon thin film (4) side, whereby light is emitted at a silicon nitride film (3).
US08330139B2
Some embodiments include a memory device and methods of forming the same. The memory device can include an electrode coupled to a memory element. The electrode can include different materials located at different portions of the electrode. The materials can create different dielectrics contacting the memory elements at different locations. Various states of the materials in the memory device can be used to represent stored information. Other embodiments are described.
US08330134B2
Various embodiments related to monitoring for optical faults in an optical system are disclosed. For example, one disclosed embodiment provides, in an optical system comprising a light source, a light outlet, and an optical element disposed between the light source and the light outlet, a method of monitoring for optical system faults. The method includes detecting, via a light sensor directed toward an interface surface of the optical element closest to the light source, an intensity of light traveling from the interface surface of the optical element to the light sensor, and comparing an intensity of light detected to one or more threshold intensity values. The method further includes identifying an optical system fault condition based on comparing the intensity of light detected to one or more threshold values, and modifying operation of the optical system.
US08330133B2
Embodiments of the invention are directed to a support frame for alleviating the weight and stress inflicted upon the shoulders and neck of individual caused by wearing a radiation shield garment and methods of use thereof. In one embodiment, the support frame comprises an elongated upper vertical back members slidably coupled to a lower vertical back member to provide vertical height adjustment; a lower back support panel coupled to the lower vertical back member to provide lower back support to the wearer; and a pair of shoulder members attached to the upper top end of the elongated vertical back member to support shoulder regions of the radiation shield garment.
US08330125B2
A beam line ion implanter includes an ion source configured to generate an ion beam, a scanner configured to scan the ion beam to produce a scanned ion beam having trajectories which diverge from a scan origin, and a focusing element having a focusing field positioned upstream of the scanner configured to focus the ion beam to a focal point at the scan origin. A method of ion beam tuning includes generating an ion beam, focusing the ion beam to a focal point positioned at a scan origin, and scanning the ion beam to produce a scanned ion beam having trajectories which diverge from the scan origin.
US08330114B2
Systems that increase the position resolution and granularity of double sided segmented semiconductor detectors are provided. These systems increase the imaging resolution capability of such detectors, either used as Compton cameras, or as position sensitive radiation detectors in imagers such as SPECT, PET, coded apertures, multi-pinhole imagers, or other spatial or temporal modulated imagers.
US08330101B2
A method of replacing an ion source in a mass spectrometer (MS) system is provided, where the ion source includes an ionization volume, at least one ionizing element and at least one focusing element, and where the mass MS system includes the ion source, a vacuum chamber that houses the ion source, and an interlock chamber. The method includes opening a valve between the interlock chamber and the vacuum chamber, moving the ion source into the interlock chamber through the opened valve and closing the valve, and removing the ion source from the interlock chamber. The ion source may further include means for plugging into a docking station in substantially one action, where the docking station provides sufficient electrical connection, upon plugging with the ion source, for operation of the ion source.
US08330089B2
It is intended to provide a CMOS image sensor with a high degree of pixel integration. A solid-state imaging device comprises a signal line formed on a Si substrate, an island-shaped semiconductor formed on the signal line, and a pixel selection line. The island-shaped semiconductor includes: a first semiconductor layer connected to the signal line; a second semiconductor layer located above and adjacent to the first semiconductor layer; a gate connected to the second semiconductor layer through an insulating film; and a charge storage section comprised of a third semiconductor layer connected to the second semiconductor layer and adapted, in response to receiving light, to undergo a change in amount of electric charges therein; a fourth semiconductor layer located above and adjacent to the second and third semiconductor layers. The pixel selection line is connected to the fourth semiconductor layer formed as a top portion of the island-shaped semiconductor.
US08330084B2
A temperature-control circuit of a heating line and a temperature-control method thereof are disclosed. The method comprises steps of: outputting a forward square-wave signal by a first forward square-wave signal generation circuit; outputting a reverse square-wave signal by a reverse square-wave signal generation circuit; and outputting a varied forward square-wave signal by a second forward square-wave signal generation circuit. Above square-wave signal generation circuits are respectively connected with an AND gate. When the input square-wave signals are simultaneously logic high, a switch is triggered by a trigger circuit to heat the heating wire. When the heating wire's temperature increases, the forward square-wave signal output by the second forward square-wave signal generation circuit is changed so as to render these input square-wave signals non-simultaneously logic high and not to trigger the switch in order to stop the heating wire's heating and keep the heating wire at a certain temperature range.
US08330081B2
A heating device for an optical fiber may include a crucible body having an optical fiber receiving slotted passageway therein for receiving the optical fiber therein, and a heating element receiving passageway therein adjacent the optical fiber receiving slotted passageway and spaced apart therefrom. The heating device may include a respective electrically powered resistance heating element enclosed within the heating element receiving passageway for heating the optical fiber within the optical fiber receiving slotted passageway.
US08330072B2
A substrate processing system includes a first, movable surface tension gradient device, a dicing device and a system controller. The first, movable surface tension gradient device is capable of supporting a first process within a first meniscus. The first meniscus being supported between the first surface tension gradient device and a first surface of the substrate. The first movable surface tension gradient device capable of being moved relative to the first surface of the substrate. The dicing device is oriented to a desired dicing location. The desired dicing location being encompassed by the meniscus. The system controller is coupled to the dicing device and the surface tension gradient device. The system controller includes a process recipe. A method for dicing a substrate is also described. The method of dicing a substrate including placing a substrate in a substrate dicing system, forming a meniscus between a proximity head and a first surface of the substrate, dicing the substrate at a desired dicing location and simultaneously capturing any particles and contaminants generated by dicing the substrate within the meniscus, the meniscus including the desired dicing location and moving the meniscus in a desired dicing direction.
US08330071B2
Generating pulsed discharge between an end surface of an electrode and an end face portion of a metallic plate, to attrite the electrode, to form in the end surface of the electrode a recess conforming to a shape of the end face portion of the metallic plate, having the electrode making a relative movement in a direction perpendicular to a lateral side of the metallic plate, generating pulsed discharge between an internal side face of the electrode recess and a lateral face of the end face portion of the metallic plate, to form an auxiliary coat on the lateral face of the end face portion of the metallic plate, and generating pulsed discharge between a bottom face of the electrode recess and a top face of the end face portion of the metallic plate, to form a cladding layer on the end face portion of the metallic plate.
US08330067B2
The apparatus, which serves for the optical inspection of workpieces, comprises a transport device driven by a drive unit, which transport device is supplied with workpieces delivered by a loading device, which workpieces are transported by the transport device to at least one inspection position, where an optical inspection is performed, and further to at least one discharge position, where the inspected workpieces are selectively extractable by a discharge device. According to the invention, a plurality of transparent receiving bodies are firmly mounted or rotatably supported on the transport device, each of the receiving bodies comprising a recess, into which the workpieces can be inserted individually or in groups, and wherein an inspection radiation can be guided through each receiving body in order to image the held workpieces.
US08330060B2
A weighing station for weighing and sorting objects to be weighed, comprising a rotating conveyor element for transporting the objects further in that, in a conveying step, said conveyor element can rotate by a specifiable angle of rotation about its axis.
US08330057B2
The food calorie counting system relates to a calorie counting system that utilizes a container with at least one chamber for holding food materials, sensitive scales integrated into the chambers to weigh the food, and a processor to calculate the number of calories in the food items based on weight, type of food and method of preparation. The number of calories is then displayed on a display device to a user. The system may be used as a stand-alone device, or may further utilize an external central control unit where information from the container is transmitted to the external control unit for processing, food calorie calculation and transmission back to the containers for display.
US08330052B2
A method for producing a joined structure, containing: after placing an anisotropic conductive film in the predetermined manner, placing a wiring member containing a wiring plate formed thereon, where the wiring plate has a resist region in which the wiring plate is covered with a resist layer, and a second electrode region in which the wiring plate is not covered with the resist layer, so that the edge of the resist region at a boundary with the second electrode region comes above the chamfer part of the substrate; and heating and compressing the anisotropic conductive film from the side of the wiring member to melt and make the anisotropic conductive film flow into the side of the resist region to thereby cover the second electrode region with the anisotropic conductive film, so as to electrically connect the first electrode region and the second electrode region.
US08330047B2
A first insulating layer is formed on a suspension body and a wiring trace is formed on the first insulating layer. In addition, a ground trace is formed on the first insulating layer so as to extend along the wiring trace on one side of the wiring trace with a spacing therebetween. A second insulating layer is formed on the first insulating layer to cover the wiring trace and the ground trace. On the second insulating layer, a wiring trace is formed at a position above the wiring trace. A third insulating layer is formed on the second insulating layer to cover the wiring trace. The width of the wiring trace is set larger than the width of the wiring trace. At least a partial region of the ground trace and at least a partial region of the wiring trace are opposite to each other with part of the second insulating layer sandwiched therebetween.
US08330040B2
Photovoltaic cells and methods for the manufacture of photovoltaic cells are described. Operative layers of the photovoltaic cell are deposited onto a superstrate having a plurality of spaced ramps, allowing for the individual cells to be connected in series with minimal loss of the efficiency due to dead space between the cells.
US08330034B2
A musical accompaniment system is described including a fretted, stringed electric musical instrument, a floor unit, interface units and connecting cables. Designated frets of the instrument are divided into sections that output to a switching component that sends MIDI note # data to a synthesizer when strings of instrument contact designated fret sections. The floor unit includes actuators that output to the synthesizer when tapped by the user. The user taps on the actuators with his or her feet and thereby actuates accompaniment notes that are generated in the rhythms in which they are tapped. Accompaniment notes generated by the process are designated by notes and chords being fingered on the instrument. Methods are described that facilitate the actuating and generating of accompaniment notes in the musical style of traditional bass accompaniment through the use of the system. A method is described to facilitate the system that includes string/fret coordinates that designate appropriate MIDI note # data and accompaniment note for fingering formations of traditional guitar chords used in popular music. Additional methods are described that obviate the generating of extraneous accompaniment notes normally associated with fretted guitar-like instruments. An additional actuator is described that actuates a designated user-programmable bass note or accompaniment sound with each tap by the user on the actuator.
US08330025B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH816791. The invention thus relates to the plants, seeds and tissue cultures of the variety CH816791, and to methods for producing a corn plant produced by crossing a corn plant of variety CH816791 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH816791.
US08330024B1
A novel maize variety designated X8M147 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8M147 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8M147 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8M147, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8M147. This invention further relates to methods for producing maize varieties derived from maize variety X8M147.
US08330022B1
A novel maize variety designated X18A642 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18A642 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18A642 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18A642, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18A642. This invention further relates to methods for producing maize varieties derived from maize variety X18A642.
US08330019B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH227660. The invention thus relates to the plants, seeds and tissue cultures of the variety CH227660, and to methods for producing a corn plant produced by crossing a corn plant of variety CH227660 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH227660.
US08330010B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH117231. The invention thus relates to the plants, seeds and tissue cultures of the variety CH117231, and to methods for producing a corn plant produced by crossing a corn plant of variety CH117231 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH117231.
US08330009B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH676009. The invention thus relates to the plants, seeds and tissue cultures of the variety CH676009, and to methods for producing a corn plant produced by crossing a corn plant of variety CH676009 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH676009.
US08330005B2
A potato cultivar designated FL 2137 is disclosed. The invention relates to the tubers of potato cultivar FL 2137, to the seeds of potato cultivar FL 2137, to the plants of potato FL 2137, to the plant parts of potato cultivar FL 2137 and to methods for producing a potato plant produced by crossing potato cultivar FL 2137 with itself or with another potato variety. The invention also relates to methods for producing a potato plant containing in its genetic material one or more transgenes and to the transgenic potato plants and plant parts produced by those methods. This invention also relates to potato cultivars or breeding cultivars and plant parts derived from potato variety FL 2137, to methods for producing other potato cultivars, lines or plant parts derived from potato cultivar FL 2137 and to the potato plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid potato tubers, seeds, plants and plant parts produced by crossing potato cultivar FL 2137 with another potato cultivar.
US08330004B2
A potato cultivar designated FL 2126 is disclosed. The invention relates to the tubers of potato cultivar FL 2126, to the seeds of potato cultivar FL 2126, to the plants of potato FL 2126, to the plant parts of potato cultivar FL 2126 and to methods for producing a potato plant produced by crossing potato cultivar FL 2126 with itself or with another potato variety. The invention also relates to methods for producing a potato plant containing in its genetic material one or more transgenes and to the transgenic potato plants and plant parts produced by those methods. This invention also relates to potato cultivars or breeding cultivars and plant parts derived from potato variety FL 2126, to methods for producing other potato cultivars, lines or plant parts derived from potato cultivar FL 2126 and to the potato plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid potato tubers, seeds, plants and plant parts produced by crossing potato cultivar FL 2126 with another potato cultivar.
US08330003B2
A soybean cultivar designated S080093 is disclosed. The invention relates to the seeds of soybean cultivar S080093, to the plants of soybean S080093, to plant parts of soybean cultivar S080093, and to methods for producing a soybean plant produced by crossing soybean cultivar S080093 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080093, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080093, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080093 with another soybean cultivar.
US08330001B1
A novel soybean variety, designated XBP27002 is provided. Also provided are the seeds of soybean variety XBP27002, cells from soybean variety XBP27002, plants of soybean XBP27002, and plant parts of soybean variety XBP27002. Methods provided include producing a soybean plant by crossing soybean variety XBP27002 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XBP27002, methods for producing other soybean varieties or plant parts derived from soybean variety XBP27002. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP27002 are further provided.
US08329999B2
A soybean cultivar designated S080104 is disclosed. The invention relates to the seeds of soybean cultivar S080104, to the plants of soybean S080104, to plant parts of soybean cultivar S080104, and to methods for producing a soybean plant produced by crossing soybean cultivar S080104 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080104, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080104, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080104 with another soybean cultivar.
US08329995B2
Non-naturally occurring soybean plants and seeds having reduced isoflavones are provided. A series of independent non-transgenic human-induced mutations found in one or more isoflavone synthase genes of soybean; soybean plants having these mutations in one or more isoflavone synthase genes; and a method of creating and finding similar and/or additional mutations of the isoflavone synthase gene by screening pooled and/or individual DNA of soybean plants. The results are soybean plants and seeds having reduced isoflavones.
US08329992B2
Polynucleotides encode polypeptides for increasing the rate of growth of plants. Introduction of the polynucleotides into plants produces plants having altered characteristics, such as increased growth, increased leaf area and reduced fertility. Expression of polypeptides in plants or plant cells promotes cell division. Expression of the polynucleotides in plants in the antisense orientation produces plants that are sterile or have smaller leaves.
US08329990B2
A novel crop grain filling gene (GIF1) and the applications thereof are presented in the invention. The GIF1 gene can be applied to control grain filling, enhance crop yield or quality, or improve disease resistance or storage stability of crop grains. A method for improving crops is also presented in the invention. The GIF1 gene shows valuable potentials in controlling crop yield, quality, storage, and resistance to diseases.
US08329989B2
The present invention provides a transgenic soybean event MON87705, and cells, seeds, and plants comprising DNA diagnostic for the soybean event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said soybean event in a sample, methods for detecting the presence of said soybean event nucleotide sequences in a sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said soybean event in a sample, growing the seeds of such soybean event into soybean plants, and breeding to produce soybean plants comprising DNA diagnostic for the soybean event.
US08329988B2
The invention relates to a method of increasing the resistance to one or more penetrating pathogen(s) in a monocotyledonous or dicotyledonous plant or a part of a plant, for example in an organ, tissue, a cell or a part of a plant cell, for example in an organell, wherein a DNA sequence which codes for an armadillo repeat ARM1 protein and which mediates an increased pathogen resistance, preferably an increased resistance to fungal pathogens, is increased into, and expressed in, the plant or plant cell; or wherein an endogenous DNA sequence which codes for an armadillo repeat ARM1 protein and which mediates an increased pathogen resistance, preferably an increased resistance to fungal pathogens, is increased in the plant or plant cell in comparison with the original, or wild-type, plant, or wherein the endogenous gene sequence or preferably the 5′-untranslated region (5′UTR) is modified in comparison with the original sequence. The invention also relates to plants, to parts of a plant, for example an organ, tissue, a cell or a part of a plant cell, for example an organelle, which are obtained by the above methods, and to corresponding propagation material.
US08329985B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH861515. The invention thus relates to the plants, seeds and tissue cultures of the variety CH861515, and to methods for producing a corn plant produced by crossing a corn plant of variety CH861515 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH861515.
US08329983B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH136255. The invention thus relates to the plants, seeds and tissue cultures of the variety CH136255, and to methods for producing a corn plant produced by crossing a corn plant of variety CH136255 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH136255.
US08329981B2
A genetically modified mouse characterized in that it does not comprise a nucleic acid sequence which itself encodes any endogenous immunoglobulin heavy chain constant region locus polypeptide.
US08329967B2
A process for producing a blended fuel from a paraffin rich component and a cyclic rich component, where each of the components are generated from a renewable feedstock, is presented. The paraffin rich component is generated from glycerides and free fatty acids in feedstocks such as plant and animal oils. The cyclic rich component is generated from biomass derived pyrolysis oil. The source of the animal or plant oil and the biomass may be the same renewable source.
US08329966B2
Synthetic base oil composition comprising dialkyl aromatic compound with alkyl side chain carbon number from C10 to C28, or preferably C11 to C24, or even more preferably, C12 to C18, wherein the branching characteristics of the alkyl side chain has a total methyl number (TMN) determined by C13 NMR spectroscopy to be from more than 2.1 to less than 3.5, or preferably from 2.15 to 3.25, or even more preferably from 2.2 to 3.0, or a branching index (BI) from more than 0.1 to less than 1.5, or more preferably, 0.15 to 1.25, or even more preferably, 0.2 to 1.0. The synthetic base oil composition has a combination of high viscometric index, low volatility, superior low temperature properties, and improved thermal/oxidation stability, and is particularly suitable to be used as a premium synthetic base stock, second base oil component, or additive for lubricant and additive package applications.
US08329962B2
Methods and systems for the synthesis of alcohol are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of olefins in water. The high shear device may allow for lower reaction temperatures and pressures and may also reduce reaction time. In an embodiment, a method of making an alcohol comprises introducing an olefin into a water stream to form a gas-liquid stream. The method further comprises flowing the gas-liquid stream through a high shear device so as to form a dispersion with gas bubbles having a mean diameter less than about 1 micron. In addition, the method comprises contacting the gas-liquid stream with a catalyst in a reactor to hydrate the olefin gas and form an alcohol.
US08329955B2
Amino compounds are continuously prepared by hydrogenation of nitrile compounds in the presence of a catalyst, and more particularly diamines are prepared by the continuous hydrogenation of dinitrile compounds in the presence of a Raney metal catalyst and in the absence of an alcoholic solvent; the subject process includes extracting a portion of the catalyst present in the reaction medium, the extracted portion of the catalyst is submitted to a regeneration for providing a catalyst having a catalytic activity lower than that of a fresh catalyst but still high and the regenerated catalyst is recycled to the reaction medium together with fresh catalyst according to a predetermined ratio, whereby the consumption of catalyst is reduced per ton of amines produced.
US08329953B2
Provided are a cyclopentaphenanthrene-based compound and an organic EL device using the same. The cyclopentaphenanthrene-based compound is easy to prepare and excellent in solubility, color purity, and color stability. The cyclopentaphenanthrene-based compound is useful as a material for forming an organic layer, in particular, a light-emitting layer in an organic EL device, and as an organic dye or an electronic material such as a nonlinear optical material.
US08329945B2
The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in transcription and translation. The present invention makes available compositions and methods that can be utilized, for example to control cell proliferation and differentiation in vitro and in vivo.
US08329943B2
A method of stabilizing a hem protein which is effective against the denaturation and degradation of a hem protein typified by hemoglobin and a storage solution therefor. A method of stabilizing a hem protein and a storage solution therefor characterized in that an iminocarboxylic acid or its salt is made to coexist in a sample containing the hem protein, wherein the above-described iminocarboxylic acid is a compound represented by the following general formula (1) wherein R represents a hydrogen atom or a hydroxyl group; and X's represent each a hydrogen atom, an alkali metal or an ammonium group.
US08329936B2
The present invention relates to a method for producing cyanoacrylic acid esters. The method is based substantially on a transesterification reaction, wherein the transesterification reaction is performed in the presence of at least one transition metal catalyst that is formed by reacting at least one hydroxyl group-containing support material with at least one transition metal alkoxide.
US08329935B2
A process for efficiently producing through a small number of steps an N-substituted 2-amino-4-(substituted-oxymethylphosphinyl)-2-butenoic ester which is an intermediate for herbicide L-AMPB. The process comprises reacting a compound represented by the following formula (1): (where R1 represents C1-4 alkyl group) with a compound represented by the following formula (2): (wherein R2, R2′, and R3 each represents C1-4 alkyl and R4 represents benzyloxycarbonyl) in the presence of a base.
US08329933B2
The present invention provides an organosilicon composition comprising diethoxymethylsilane, a concentration of dissolved residual chloride, and a concentration of dissolved residual chloride scavenger that does not yield unwanted chloride salt precipitate when combined with another composition comprising diethoxymethylsilane.
US08329931B2
A catalyst for obtaining isopulegol of high diastereoselectivity by highly selective cyclization reaction of citronellal is provided. The present invention relates to an organoaluminum compound obtained by reacting at least one organoaluminumoxy compound selected from the group consisting of chain aluminoxanes, cyclic aluminoxanes and bis(dialkylaluminumoxy)alkylboranes, with at least one hydroxy compound selected from the group consisting of diarylphenols, bis(diarylphenol) compounds, biaryldiols, dimethanols and silanols.
US08329924B2
The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
US08329919B2
The invention relates to new forms of salts of valsartan or crystalline, also partly crystalline and amorphous salts of valsartan, the respective production and usage, and pharmaceutical preparations containing such a salt.
US08329913B2
An object of the present invention is to provide novel carbazole derivatives, solvates thereof, or pharmaceutically acceptable salts thereof having an excellent adipose tissue weight reducing effect, hypoglycemic effect, and hypolipidemic effect, which are useful as a preventive and/or therapeutic agent for fatty liver, obesity, lipid metabolism abnormality, visceral adiposity, diabetes, hyperlipemia, impaired glucose tolerance, hypertension, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, and the like.The above-mentioned object can be achieved by carbazole derivatives, solvates thereof, or pharmaceutically acceptable salts thereof, wherein the carbazole derivatives are represented by the following general formula (I): (In the formula (I), the ring A represents phenyl group or the like; X represents —O— or the like; Y represents ═N— or the like; a and b represent methylene group or the like; both V and Z represent —O— or the like; W represents a C1-C10 alkylene group whose 1 or 2 hydrogen atoms may be substituted by a phenyl group or a C1-C6 alkyl group; 1,2-phenylene group; 1,3-cyclohexyl group; or the like; R1 represents methyl group or the like; R2 represents methoxy group or the like; and R3 represents carboxy group or the like.).
US08329911B2
The invention provides compounds of formula I: wherein a, b, c, p, W, A, X1, R1, R2, R3, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
US08329904B2
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein n, m, A, R1 and R2 have the significance given in the description. The compounds are useful as HSL inhibitors and may be used in the treatment or prophylaxis of diabetes, dyslipidemia, atherosclerosis or obesity.
US08329888B2
The present invention is directed to pharmaceutical and therapeutic compositions which comprise RNA complexes comprising an antisense strand and a discontinued passenger strand capable of regulating gene expression. The use of a discontinued passenger strand reduces off target effects of the RNA complexes and also has other advantages.
US08329883B2
Methods for regulating the serine protease of Plasmodium. Recombinant DNA constructs which express the Plasmodium serine protease, especially those comprising a sub2 3′UTR and coding segment which express a SUB2 a serine protease. Recombinant Plasmodium containing such constructs and exhibiting increased virulence. Methods for detecting virulent Plasmodium strains by detecting the presence or amount of sub2 3′UTR sequences, sub2 mRNA or cDNA, SUB2 polypeptide expression, or other Plasmodium proteins, such as AMA1 or MSP1, which have been post-translationally modified by SUB2.
US08329878B2
The present invention discloses improved methods of disaggregating protein aggregates, and refolding denatured proteins, using high pressure. In particular, the present invention provides for the use of agitation, high temperature, “stepped” depressurization, dialysis and dilution under pressure to increase the speed and extent of aggregate dissolution and protein refolding.
US08329877B2
The object of the present invention is a procedure for the distribution, separation and purification in aqueous solution of recombinant proteins, based on the utilization of polypeptides with choline affinity. The invention is based on a phenomenon consisting of that two aqueous solutions with determinated components can be mixed, being distributed finally in two phases with different density. The fusionated proteins to said polypeptides with choline affinity are preferably located in one of the phases, while most of the cell extract proteins tend to go to the opposite phase. After a series of washings for removing the rest of the not desired material, this location can be inverted through the addition of a soluble molecule with affinity by the polypeptide fusionated to the protein of interest. This procedure allows modulating at convenience the presence of the protein or polypeptide of interest in one phase or another, possibiliting its purification with a high yield and purity grade. The invention represents an economic and scalable way of recombinant protein separation labelled preferably with choline-binding domains.
US08329873B2
Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family.
US08329870B2
The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous solutions or specifically for the formation of water-soluble covalent fibrinogen conjugates. A preferred conjugate is a hyaluronic acid-fibrinogen conjugate and fibrin adhesive, clot or matrix derived from it. Methods of preparation and methods of use in tissue repair and regeneration are also disclosed.
US08329865B2
An antimicrobially active peptide comprises the DCD protein or a fragment of DCD, preferably derived from the C-terminal region.
US08329858B2
A method of controlling oil-absorbing properties of a silicone rubber powder characterized by keeping a silicone rubber powder in hot storage at a temperature in the range of 40° C. to 150° C. or in cold storage at a temperature in the range of 0° C. to 10° C.
US08329855B2
Disclosed are new semiconductor materials prepared from thienocoronene-imide-based small molecule and/or polymeric compounds. Such compounds can exhibit high carrier mobility and/or good current modulation characteristics. In addition, the compounds of the present teachings can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.
US08329850B2
Golf equipment including compositions including castable formulations that have low material hardness and increased shear resistance. The compositions may be used in any layer of a golf ball including cores, intermediate layers, and covers and result in high spin rates.
US08329849B2
An organic silicon compound includes a specific alkoxyorganopolysiloxane portion, a portion including an alkoxysilane group, the portion being bonded to the polysiloxane portion, and a portion including a resin-compatible chain or a reactive functional group, the portion being bonded to the polysiloxane portion.
US08329848B2
An object of the present invention is to provide a novel ethylene-α-olefin copolymer excellent in crosslinking properties; a foamed molded article having a low specific gravity and a low compression set (CS) and a composition capable of producing the foamed molded article, footwear parts composed of a foamed molded article; an ethylenic copolymer composition excellent in balance between weather resistance and mechanical strength, and an electric wire coating material and an electric wire sheath using the ethylenic copolymer composition; and a thermoplastic elastomer capable of producing a molded article excellent in balance between mechanical strength and toughness. The ethylenic copolymer (A) of the present invention is a copolymer composed of only ethylene and an α-olefin having 3 to 20 carbon atoms, and is characterized in that vinyl-group content (a) per 1000 carbon atoms as measured by infrared absorption spectroscopy, MFR10/MFR2.16 (b), and the specific gravity (c) are within a specific range.
US08329845B2
The present invention provides a divided redox-curing type composition including a first part in which at least an oxidizing agent (b) is dissolved in a first radical monomer including a radical monomer (a) having an acidic group and/or a hydrophilic group; and a second part in which at least an aromatic sulfinate (d) is dispersed in a second radical monomer including a radical monomer (c) having neither an acidic group nor a hydrophilic group. According to the present invention, a redox-curing type composition capable of securing a time necessary for an adhesion operation and exhibiting high bond strength not only at the initial stage of adhesion but also over a long period of time thereafter in application to a wetting material such as a tooth or a bone as well as a tooth crown repairing material such as a metal or porcelain.
US08329840B2
The present invention relates to a photo-reactive norbornene-based copolymer which has superior miscibility to various organic solvents or additives while exhibiting superior liquid crystal alignment property and can be preferably used to an alignment layer of liquid crystal display device, a method of preparing the same, and an alignment layer including the same.
US08329828B2
A heat-shrinkable polyester film is provided which exhibits a high shrinkability in a high-temperature range with a main shrinking direction oriented in a longitudinal direction thereof, though not shrinking in the longitudinal direction in a low-temperature range, possesses an extremely high mechanical strength in a transverse direction orthogonal to the main shrinking direction, and, in particular, can be utilized suitably as a film for forming a jacket label of a battery or in similar applications.
US08329827B2
A sulfonated block copolymer which is solid and non-dispersible in water having at least two polymer end blocks A and at least one interior block B wherein each A block is a polymer block resistant to sulfonation and each B block is a polymer block susceptible to sulfonation, wherein the A and B blocks do not contain any significant levels of olefinic unsaturation. Each A block includes one or more segments selected from polymerized (i) ethylene, (ii) monomers of conjugated dienes having a vinyl content less than 35 mol percent prior to hydrogenation, and (iii) mixtures thereof; and each B block comprising segments of one or more polymerized vinyl aromatic monomers selected from (i) unsubstituted styrene monomers, (ii) ortho-substituted styrene monomers, (iii) meta-substituted styrene monomers, (iv) alpha-methylstyrene, (v) 1,1-diphenylethylene, (vi) 1,2-diphenylethylene and (vii) mixtures thereof.
US08329815B2
A silicon-containing polymer which is represented by general formula (5) below and has a weight-average molecular weight in the range from 500 to 500,000: (In the formula, A2 is an organic group of 2-10 carbons, having a carbon-carbon unsaturated group; R3 is an alkylene group of 1-20 carbons, a bivalent aromatic group of 6-20 carbons, or a bivalent alicyclic group of 3-20 carbons; n is 0 or 1; R4 is a hydrogen atom or an alkyl group of 1-10 carbons (R4 in one molecule may be the same type or a combination of two or more different types.); each of x and y is a positive number; each of w and z is 0 or a positive number; 0≦z/(w+x+y)≦2; and 0.01≦y/(w+x)≦5), and the heat-resistant resin composition comprising the silicon-containing polymer.
US08329814B2
Briefly described, embodiments of this disclosure include ink formulation and modified pigments. One exemplary modified pigment, among others, includes a pigment A represented by the formula in FIG. 3.
US08329813B2
A process for reducing the fluoroether carboxylic acid or salt content of aqueous fluoropolymer dispersion. The fluoroether carboxylic acid or salt employed comprises fluoroether carboxylic acid or salt having the formula below: [R1—O-L-COO−]Y+ wherein R1 is a linear, branched or cyclic partially or fully fluorinated aliphatic group which may contain ether linkages; L is a branched partially or fully fluorinated alkylene group which may contain ether linkages; and Y+ is hydrogen, ammonium or alkali metal cation. The process comprises adding stabilizer to the aqueous fluoropolymer dispersion to form a stabilized aqueous fluoropolymer dispersion and heating the stabilized aqueous fluoropolymer dispersion to decarboxylate the fluoroether carboxylic acid or salt to produce a fluoroether byproduct. At least a portion of the fluoroether byproduct is removed.
US08329806B2
The method for producing flaky-glass granules of the present invention is a method for producing flaky-glass granules by allowing a plurality of glass flakes to be bonded to each other so as to be granulated. The method includes the steps of: (I) adding at least one liquid selected from water and a volatile organic solvent to the plurality of glass flakes and stirring a resultant mixture, and (II) drying the plurality of glass flakes stirred with the liquid added thereto. Unlike conventional flaky-glass granules, the flaky-glass granules produced by this method contain neither a binder nor a surface treatment agent for bonding the glass flakes to each other. Thus, when mixed into a thermoplastic resin to be molded at a high temperature, the flaky-glass granules cause neither foam inclusion nor discoloration in a molded article of the resin.
US08329801B2
The invention provides a self-adhesive composition in powder form for the coating of metallic substrates, composed of homopolyamide (A) selected from PA11 and PA12, copolyamide (B), calcium carbonate and, optionally, at least one component selected from a pigment or dye, an anti-crater agent or spreading agent, a reductant, an antioxidant, a reinforcing filler, a UV stabilizer, a fluidizing agent and a corrosion inhibitor, said composition being devoid of silane-type adhesion promoter or of an adhesion promoter containing an epoxy, alcohol and/or carboxylic acid function, or derivatives thereof, and having a dry-state modulus and/or a wet-state modulus of greater than or equal to 2200 MPa [Standard NF EN ISO 527]. The invention also relates to a composite material comprising a metallic substrate directly coated with a coating film resulting from the melting of said composition, the adhesion of the coating film to the metallic substrate being greater than 3 after 2000 hours of salt fog before and after drying, in accordance with Standard NFT 58-112.
US08329794B2
A polymer composition of a compatibilized silica in blends of acrylonitrile butadiene polymer and styrene butadiene polymer comprising six to ninety percent by weight of a compatibilized silica, at least one percent by weight of a coupling agent, at least one percent by weight of a styrene butadiene polymer, and at least one percent by weight of an acrylonitrile butadiene polymer is described herein. The polymer composition can have a minimum amount of at least ten percent by weight of 15:50 ratio, acrylonitrile to butadiene polymer, with the remainder being compatibilized silica.
US08329788B2
The present invention includes rubber compositions, rubber articles and tires formulated to prevent ozone attack. A particular embodiment of the present invention includes a tire comprising a rubber structure, the rubber structure comprising an essentially unsaturated rubber elastomer, between 0.1 and 0.45 phr (parts by weight per hundred parts by weight of the rubber elastomer) of a particular compound 2,4,6-Tris-(N-1,4-dimethylpentyl-p-phenylenediamino)-1,3,5-triazine and between 0.5 and 2 phr of a phenolic resin.
US08329782B2
A process for reducing fluorosurfactant content of a stabilized fluorosurfactant-containing aqueous fluoropolymer dispersion comprising contacting the stabilized fluorosurfactant-containing aqueous fluoropolymer dispersion with an anion exchange resin comprising a polymer and quaternary ammonium functional groups to reduce fluorosurfactant content, the functional groups being resistant to degradation which releases trialkylamines. The anion exchange resin is separated from the dispersion after the fluorosurfactant content has been reduced.
US08329779B2
The invention relates to a translucent or transparent, colored enamel that contains metal nanoparticles that lost their natural tendency to aggregate with each other, and having a color essentially provided by the reflection of light. The nanoparticles have lost their natural capability to aggregate with each other due to the application of a coating, or because they have been functionalised electrostatically or using highly sterically hindered entities or using hydrophilic entities located at the surface thereof. The nanoparticles may be gold nanoparticles that impart an intense and deep red to said enamel.
US08329775B2
Azo compounds that block visible light are disclosed. These light absorbers are particularly suitable for use in intraocular lens materials.
US08329767B2
The present invention is a method for forming a hydrophilic polymer membrane for use in a membrane electrode assembly, comprising the polymerization of a material or materials from which the membrane may be formed, wherein the polymerization is by UV curing.
US08329765B2
Process for converting synthesis gas to hydrocarbons in a slurry reactor in the presence of a Fischer-Tropsch catalyst comprising cobalt and zinc oxide. The process is carried out by a) activating the Fischer-Tropsch catalyst with a reducing gas consisting of hydrogen and an inert gas at a temperature between 330 and 400° C., and b) contacting the activated Fischer-Tropsch catalyst from step a) with synthesis gas in the slurry reactor in order to convert the synthesis gas into hydrocarbons.
US08329751B2
The invention relates to aryl-sulphonamido compounds endowed with inhibitory activity against metallo proteases MMP, having formula (I) below wherein R, R1, R2, R3, R4, R5, n and m have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of degenerative disorders.
US08329750B2
Methods for treating vasomotor symptoms associated with menopause are described.
US08329746B2
A method and composition for treating osteoarthritis with ion-channel regulators is disclosed. The ion-channel regulators are used alone or in combination with other osteoarthritis treatment agents, including but not limited to injectable agents such as viscosupplements and steroids. A composition comprising one or more ion-channel regulator(s) and one or more osteoarthritis treatment agent(s) is also disclosed.
US08329743B2
The present invention provides a composition comprising polyisoprenylated benzophenone derivative and at least one component selected from stilbene derivative and anthocyanins. The composition inhibits adipogenesis and is therefore useful in treating obesity or weight loss.
US08329728B2
This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. In particular, the disclosure provides for substituted imidazo[4,5-c]pyridine compounds having the general formula their salts, pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.
US08329725B2
The invention relates to annelated pyrrolidin sulfonamides with oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula (I), in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
US08329704B2
The present invention concerns aryl and heteroaryl substituted pyrazinone derivatives having antagonistic melanin-concentrating hormone (MCH) activity, in particular MCH-1 activity according to the general Formula (I) a pharmaceutically acceptable acid or base addition salt thereof, a stereochemically isomeric form thereof, an N-oxide form thereof or a quaternary ammonium salt thereof, wherein the variables are defined in Claim 1. It further relates to their preparation, compositions comprising them and their use as a medicine. The compounds according to the invention are useful for the prevention and/or treatment of psychiatric disorders, including but not limited to anxiety, eating disorders, mood disorders, such as bipolar disorders and depression, psychoses, such as schizophrenia, and sleeping disorders; obesity; diabetes; sexual disorders and neurological disorders.
US08329702B2
The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
US08329700B2
Pyrazine compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein m, n, p, R1, R2, R3, R4, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, Y and Z are defined in the specification, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
US08329697B2
The present invention is directed to AHCY inhibitors of formula (I) which are useful in the treatment of diseases characterized by high homocysteine levels, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases characterized by high homocysteine levels.
US08329695B2
The present invention relates to a crystalline form a dihydropteridione derivative, namely a crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.
US08329692B2
Compounds selected from the group according to Claim 1 are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
US08329690B2
Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: wherein R1, R2, R3, R4, R5, and Q1 are defined herein.
US08329689B2
The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (HCV, HBV), human immune deficiency (HIV), atypical pneumonia (SARS) and bird flu. The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R14 and R24 independently of each other are an aminogroup substituent selected for hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heterocyclyl, or R14 and R24 together with a nitrogen atom, with which they are bound, form through R14 and R24 optionally substituted azaheterocyclyl or guanidyl; R2 is analkyl substituent selected from hydrogen, an optionally substituted mercaptogroup, optionally substituted aminogroup and optionally substituted hydroxyl; R3 is lower alkyl, R5 is an hydrogen atom or R5 together with an oxygen atom with which it is linked or R24 together with a nitrogen atom with which it is linked close, via R5 and R24 an oxazine cycle; R6 is a cyclic system substituent selected for hydrogen, a halogen atom, cyanogroup, optionally substituted aryl or substituted heterocyclyl.
US08329688B2
Compounds of a formula entitled, trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid, as a free acid or a pharmaceutically acceptable salt thereof; and hydrates and other solvates in crystalline form; pharmaceutical formulations; and methods of use are disclosed.
US08329687B2
The present invention provides a compound having a superior serotonin 5-HT2C receptor activating action, which is represented by the formula wherein A is —OR1 or —S(O)pR2, R1 and R2 are the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group to optionally having substituent(s), and p is 0, 1 or 2, or a salt thereof.
US08329686B2
Novel isatin analogues, including isatin analogues comprising Michael Acceptors (IMAs) are disclosed. Further disclosed are methods of synthesis of the isatin analogues, and uses of the analogues, including inhibition of caspase-3 and caspase-7, and in vivo imaging of apoptosis by Positron emission tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
US08329684B2
The present invention relates to novel cephalosporin derivatives represented by Chemical Formula 1. Wherein, X, Y, L, R1, and R2 are as same as defined in the description of the invention. The present invention also relates to pharmaceutical antibiotic compositions comprising a novel celphalosporin derivative represented by Chemical Formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an effective ingredient. Compounds of the present invention are effective ingredients for the broad spectrum of antibiotic resistance, exhibit low toxicity, particularly in Gram-negative bacteria, which can be useful with strong antimicrobial activity.
US08329683B2
The present invention provides compounds of formulae Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va and the therapeutic use thereof. The present invention also includes methods of treating NF2-deficient or NF1-deficient cells or neurodegenerative diseases with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. Furthermore, the present invention is directed to methods of inhibiting the growth of NF2-deficient or NF1-deficient tumors. The methods comprise contacting NF2-deficient or NF1-deficient tumor cells with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. The present invention is also directed to the combinational use of radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va with at least one additional active agent, such as one or more HSP90 inhibitors.
US08329675B2
The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.
US08329672B2
Compositions for oral and/or topical administration of a prebiotic and a physiologically active fatty acid, or a salt or ester thereof, are disclosed. The compositions are disclosed as enhancing the body's population of beneficial microorganisms for improving health and well-being.
US08329665B2
Provided herein are compounds used to inhibit the deamination enzyme responsible for the inactivation of therapeutic compounds, and methods of using them.
US08329663B2
The present disclosure provides compositions and methods for the treatment and elimination of chronic intracellular infections in cells or organisms. The compositions may include one or more acidic substances and one or more antimicrobial substances, administered in combination or separately. The methods may include administering an amount of one or more such compositions to an infected cell or organism for a period of time ranging from days to years, until the infection is substantially eliminated.
US08329660B2
The invention relates to isolated polypeptides and nucleic acids encoding polypeptides which comprise a tim-3 IgV domain and a tim-3 intracellular domain, wherein the polypeptides do not comprise a tim-3 mucin domain or a tim-3 transmembrane domain. In addition, the invention relates to methods of modulating immune responses in a subject, comprising administering to the subject a therapeutically effective amount of an agent that modulates tim-3 activity. Immune responses include, but are not limited to, immune tolerance, transplantation tolerance, Th1 responses and Th2 responses.
US08329649B2
A stable aqueous composition containing follicle-stimulating hormone, which comprises follicle-stimulating hormone and histidine as a stabilizing agent.
US08329635B2
The present invention relates to new compounds useful for the stimulation of the production of antibodies. Said compounds comprises a saccharidic tumor antigen and a polymeric scaffold. The present invention also encompasses conjugated compounds useful in ELISA assay for the selection of antibodies against saccharidic antigens.
US08329634B2
A paint thinner and cleaner includes a methyl soy ester and dibasic ester and satisfies a less than 25 grams per liter Volatile Organic Compound (VOC) rating which permits the thinner and cleaner to be used for cleaning and thinning in government regulated areas. Requirements for reducing VOCs are well recognized. The paint thinner and cleaner of the present invention performs as well as products (for example, hydrocarbon based thinners) having greater than 25 grams per liter VOC products. Further, the paint thinner and cleaner according to the present invention has less than one tenth of the hazardous ingredients present in the other paint thinners. The paint thinner and cleaner is suitable for reducing water and oil based coatings and material.
US08329632B2
New detergent compositions and the use of enzyme combinations therein are disclosed. The compositions have enhanced stability of non protease enzymes present in the compositions.
US08329623B2
The present invention provides a grease composition (7) which has a low friction and a low viscosity and is durable at a high temperature and a grease-sealed bearing (1) in which the grease composition is enclosed. The grease composition contains base oil, a thickener, and an additive. The base oil contains an ionic liquid consisting of a cation component and an anion component. The additive contains a corrosion inhibitor such as nitrites, molybdates or dibasic acid salts. The thickener is fluorine resin such as polytetrafluoroethylene. The grease composition (7) is applied to a periphery of each rolling element (4) of the grease-sealed bearing (1).
US08329619B2
Substituted quinolinones of the formula I in which the variables are defined according to the description, their agriculturally suitable salts, processes and intermediates for preparing the compounds of the formula I, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidally effective amount of at least one compound of the formula I to act on plants, their seed and/or their habitat.
US08329617B2
This invention relates to the control of plant pests, such as aphid and whitefly by treating plants with a compound which inhibits the plant pest's ability to overcome plant defense responses, such as piperonyl butoxide or propyl gallate, in combination with a compound which activates plant defense responses, such as cis-Jasmone or beta-amino butyric acid.
US08329610B2
The present invention relates to a hydrogenation catalyst composition, process for preparing the same and use thereof. The composition comprises a hydrogenation catalyst, an organonitrogen compound in an amount of 0.01%-20% by weight of the catalyst, a sulfiding agent in an amount of 30%-150% by weight of the sulfur-requiring amount calculated theoretically of the hydrogenation catalyst, and an organic solvent in an amount of 0.1%-50% by weight of the catalyst. The preparation process comprises introducing the required substances onto the hydrogenation catalyst in oxidation state. By introduction of the organonitrogen compound, sulfur and organic solvent, the hydrogenation catalyst composition of the present invention may further increase the sulfur-maintaining ratio of the catalyst during the activation, slow down the concentrative exothermic phenomenon, decrease the rate of temperature rise of the catalyst bed layer, and improve the activity of the catalyst. The process of the present invention may be used for the treatment before the application of various hydrogenation catalysts.
US08329609B2
A process for preparing an alkoxylation catalyst wherein a catalyst precursor which is formed from an alkoxylated alcohol and an alkaline earth metal compound to form a dispersion of an alkaline earth metal species is reacted with propylene oxide to propoxylate at least a portion of the ethoxylated alcohol.
US08329607B2
Provided are diesel exhaust components where palladium is segregated from a molecular sieve, specifically a zeolite, in a catalytic material. In the catalytic material, therefore, there are at least two layers: a palladium-containing layer that is substantially free of a molecular sieve and a hydrocarbon trap layer that comprises at least one molecular sieve and is substantially free of palladium. The palladium is provided on a high surface area, porous refractory metal oxide support. The catalytic material can further comprise a platinum component, where a minor amount of the platinum component is in the hydrocarbon trap layer, and a majority amount of the platinum component is in the palladium-containing layer. Systems and methods of using the same are also provided.
US08329598B2
Methods of forming a top oxide around a charge storage material layer of a memory cell and methods of improving quality of a top oxide around a charge storage material layer of a memory cell are provided. The method can involve providing a charge storage layer on a semiconductor substrate, a nitride layer on the charge storage layer, and a first poly layer on the nitride layer, and converting at least a portion of the nitride layer to a top oxide. By converting at least a portion of a nitride layer to a top oxide layer, the quality of the resultant top oxide layer can be improved.
US08329593B2
Polymer is removed from the backside of a wafer held on a support pedestal in a reactor using an arcuate side gas injection nozzle extending through the reactor side wall with a curvature matched to the wafer edge and supplied with plasma by-products from a remote plasma source.
US08329582B2
A semiconductor device comprises insulating layer including damascene patterns and formed over a semiconductor substrate, conductive line formed higher than the insulating layer within the respective damascene patterns, and interference-prevention grooves formed within the damascene patterns between sidewalls of the conductive line and the insulating layer.
US08329576B2
Methods of improving the uniformity and adhesion of low resistivity tungsten films are provided. Low resistivity tungsten films are formed by exposing the tungsten nucleation layer to a reducing agent in a series of pulses before depositing the tungsten bulk layer. According to various embodiments, the methods involve reducing agent pulses with different flow rates, different pulse times and different interval times.
US08329574B2
Flash memory devices include a pair of elongated, closely spaced-apart main active regions in a substrate. A sub active region is also provided in the substrate, extending between the pair of elongated, closely spaced-apart main active regions. A bit line contact plug is provided on, and electrically contacting, the sub active region and being at least as wide as the sub active region. An elongated bit line is provided on, and electrically contacting, the bit line contact plug remote from the sub active region.
US08329570B2
A method of manufacturing a semiconductor device, comprising, forming a first gate electrode in a first region of a semiconductor substrate and forming a second gate electrode in a second region of the semiconductor substrate, forming a first sidewall along a lateral wall of the first gate electrode and forming a second sidewall along a lateral wall of the second gate electrode, forming an oxide film to cover the semiconductor substrate, the first gate electrode, the second gate electrode, the first sidewall and the second sidewall, forming a resist above the oxide film to cover the first region, removing the oxide film in the second region by etching the oxide film with the resist serving as a mask, removing the resist, and executing a plasma process by using a gas containing chlorine with respect to the semiconductor substrate and the oxide film in the first region.
US08329568B1
In one embodiment of the present invention, a field effect transistor device is provided. The field effect transistor device comprises an active area, including a first semiconductor material of a first conductivity type. A channel region is included within the active area. A gate region overlays the channel region, and the first source/drain region and the second source/drain region are embedded in the active area and spaced from each other by the channel region. The first source/drain region and the second source/drain region each include a second semiconductor material of a second conductivity type opposite of the first conductivity type. A well-tap region is embedded in the active area and spaced from the first source/drain region by the channel region and the second source/drain region. The well-tap region includes the second semiconductor material of the first conductivity type. The first source/drain region and the second source/drain region and the well-tap region are epitaxial deposits.
US08329560B2
Disclosed are a laser processing apparatus and method that can effectively remove a low-k material formed on a wafer. A laser processing apparatus of the invention is a laser processing apparatus that processes a subject on which a low-k material is formed. The laser processing apparatus includes a laser generating unit that emits a laser beam; and an optical system that splits the laser beam emitted from the laser generating unit into two and irradiates the split laser beams onto the subject In this case, the optical system includes a pair of condensing lenses in which cut surfaces that are cut at a predetermined distance from central axes to be parallel to the central axes contact with each other, and the interval between the two split laser beams is the same as the interval between two edges of the low-k material in a removal subject region. According to the invention, after splitting a laser beam into two laser beams and primarily removing the edges of the low-k material in the removal subject region using the laser beams, the remaining low-k material between the edges is removed. As a result, it is possible to improve processing quality.
US08329549B2
Sophisticated gate stacks including a high-k dielectric material and a metal-containing electrode material may be covered by a protection liner, such as a silicon nitride liner, which may be maintained throughout the entire manufacturing sequence at the bottom of the gate stacks. For this purpose, a mask material may be applied prior to removing cap materials and spacer layers that may be used for encapsulating the gate stacks during the selective epitaxial growth of a strain-inducing semiconductor alloy. Consequently, enhanced integrity may be maintained throughout the entire manufacturing sequence, while at the same time one or more lithography processes may be avoided.
US08329548B2
A field transistor for electrostatic discharge (ESD) protection and method for making such a transistor is described. The field transistor includes a gate conductive layer pattern formed on a field oxide layer. Since the gate conductive layer pattern is formed on the field oxide layer, a thin gate insulating layer having a high possibility of insulation breakdown is not used. To form an inversion layer for providing a current path between source and drain regions, a field oxide layer is interposed to form low concentration source and drain regions overlapped by the gate conductive layer pattern.
US08329539B2
In a semiconductor device having a recessed gate electrode and a method of fabricating the same, a channel trench is formed in a semiconductor substrate by etching the semiconductor substrate. A first semiconductor layer is formed on the semiconductor substrate that fills the channel trench. A second semiconductor layer is formed on the first semiconductor layer, the second semiconductor layer having a lower impurity concentration than the first semiconductor layer.
US08329535B2
A memory device having at least one multi-level memory cell is disclosed, and each multi-level memory cell configured to store n multiple bits, where n is an integer, wherein the multiple bits are stored in a charge storage layer trapping charge carriers injected by application of a voltage to set or reset a threshold voltage Vt of the memory cell to one of 2n levels. Each memory cell may be programmed to one of 2n multiple levels, wherein each level represents n multiple bits.
US08329529B2
A method for fabricating an integrated circuit device includes providing a semiconductor substrate having a first region and a second region, e.g., peripheral region. The method forms a stop layer overlying the first and second regions and a low k dielectric layer (e.g., k<2.9) overlying the stop layer in the first and second regions. The method forms a cap layer overlying the low k dielectric layer. In an embodiment, the method initiates formation of a plurality of via structures within a first portion of the low k dielectric layer overlying the first region and simultaneously initiates formation of an isolated via structure for in the second region of the semiconductor substrate, using one or more etching processes. The method includes ceasing formation of the plurality of via structures within the first portion and ceasing formation of the isolated via structure in the second region when one or more portions of stop layer have been exposed.
US08329526B2
Dielectric cap layers of sophisticated high-k metal gate electrode structures may be efficiently removed on the basis of a sacrificial fill material, thereby reliably preserving integrity of a protective sidewall spacer structure, which in turn may result in superior uniformity of the threshold voltage of the transistors. The sacrificial fill material may be provided in the form of an organic material that may be reduced in thickness on the basis of a wet developing process, thereby enabling a high degree of process controllability.
US08329523B2
A method of fabricating an array substrate for a display device includes: forming a buffer layer on a substrate having a pixel region; sequentially forming a gate electrode of impurity-doped polycrystalline silicon, a gate insulating layer and an active layer of intrinsic polycrystalline silicon on the buffer layer in the pixel region; forming an interlayer insulating layer of an inorganic insulating material on the active layer; sequentially forming a source barrier pattern, a source ohmic contact layer and a source electrode on the interlayer insulating layer, sequentially forming a drain barrier pattern, a drain ohmic contact layer and a drain electrode on the interlayer insulating layer, and sequentially forming a first dummy pattern, a second dummy pattern and a data line on the interlayer insulating layer; forming a first passivation layer on a surface of the interlayer insulating layer including the source electrode, the drain electrode and the data line formed thereon; forming a gate line on the first passivation layer; forming a second passivation layer on a surface of the first passivation layer including the gate line formed thereon; and forming a pixel electrode on the second passivation layer.
US08329518B1
The present invention provides methods for manufacturing a thin film transistor (TFT) array substrate and a display panel. The method for manufacturing the TFT array substrate comprises the following steps: forming a plurality of gate electrodes, a gate insulating layer, a semiconductor layer, an ohmic contact layer, an electrode layer and a first photo-resist layer on a transparent substrate in sequence; patterning the first photo-resist layer; etching the ohmic contact layer and the electrode layer; coating a second photo-resist layer on the patterned first photo-resist layer and in the channels; removing the second photo-resist layer on the patterned first photo-resist layer and to allow the second photo-resist layer in the channels to remain therein; etching the semiconductor layer; removing the patterned first photo-resist layer and the second photo-resist layer; forming a passivation layer on the channels, the source electrodes and the drain electrodes; and forming a pixel electrode layer on the passivation layer. The present invention can reduce an amount of the required masks in the fabrication process, and only one wet etching is required to etch the metal material on the TFT array substrate.
US08329517B2
A method for manufacturing a pixel structure includes providing a substrate including a transistor region and a pixel region, forming at least one gate electrode on the transistor region, forming an insulating layer on the substrate to overlay the gate electrode, and forming a patterned semi-conductive layer on the surface of a portion of the insulating layer disposed on the transistor region and the pixel region. A patterned first protective layer is formed on a portion of the patterned semi-conductive layer corresponding to the gate electrode, and the patterned semi-conductive layer is doped without being overlaid by the patterned first protective layer.
US08329513B2
A method of forming a memory array includes forming first and second strings of serially-coupled memory cells respectively on first and second sides of a conductive pillar. Forming the first string of memory cells includes forming a first control gate on the first side of the conductive pillar and interposing a first charge trap between the first side of the conductive pillar and the first control gate. Forming the second string of memory cells comprises forming a second control gate on the second side of the conductive pillar and interposing a second charge trap between the second side of the conductive pillar and the second control gate. The first and second charge traps are electrically isolated from each other, and the first and second control gates are electrically isolated from each other.
US08329510B2
A method of making a semiconductor chip assembly includes providing a post, a base, an ESD protection layer and a metal layer, wherein the post extends above the base and the ESD protection layer is sandwiched between the base and the metal layer, mounting an adhesive on the base including inserting the post into an opening in the adhesive, mounting a conductive layer on the adhesive including aligning the post with an aperture in the conductive layer, then flowing the adhesive upward between the post and the conductive layer, solidifying the adhesive, then providing a conductive trace that includes a pad, a terminal and a selected portion of the conductive layer, providing a heat spreader that includes the post, the base, the ESD protection layer and an underlayer that includes at least a portion of the metal layer, then mounting a semiconductor device on the post, electrically connecting the semiconductor device to the conductive trace and thermally connecting the semiconductor device to the heat spreader.
US08329507B2
One embodiment of a semiconductor package described herein includes a substrate having a first through-hole extending therethrough; a conductive pattern overlying the substrate and extending over the first through-hole; a first semiconductor chip facing the conductive pattern such that at least a portion of the first semiconductor chip is disposed within the first through-hole; and a first external contact terminal within the first through-hole and electrically connecting the conductive pattern to the first semiconductor chip.
US08329503B1
A photovoltaic solar concentrator is disclosed with one or more transverse-junction solar cells (also termed point contact solar cells) and a lens located above each solar cell to concentrate sunlight onto the solar cell to generate electricity. Piezoelectric actuators tilt or translate each lens to track the sun using a feedback-control circuit which senses the electricity generated by one or more of the solar cells. The piezoelectric actuators can be coupled through a displacement-multiplier linkage to provide an increased range of movement of each lens. Each lens in the solar concentrator can be supported on a frame (also termed a tilt plate) having three legs, with the movement of the legs being controlled by the piezoelectric actuators.
US08329497B2
A backside illuminated imaging sensor includes a semiconductor layer and an infrared detecting layer. The semiconductor layer has a front surface and a back surface. An imaging pixel includes a photodiode region formed within the semiconductor layer. The infrared detecting layer is disposed above the front surface of the semiconductor layer to receive infrared light that propagates through the imaging sensor from the back surface of the semiconductor layer.
US08329491B2
A mechanical quantity sensor includes a first structure having a fixed portion with an opening, a displaceable portion arranged in the opening and displaceable relative to the fixed portion, and a connection portion connecting the fixed portion and the displaceable portion, a second structure having a weight portion joined to the displaceable portion and a pedestal arranged surrounding the weight portion and joined to the fixed portion, the second structure being arranged and stacked on the first structure, a first base connected to the fixed portion and arranged and stacked on the first structure, and a second base connected to the pedestal and arranged and stacked on the second structure. The weight portion is adjusted in thickness after the first structure is made and before the second base and the second structure are joined.
US08329482B2
Methods and devices for light emitting diode (LED) chips are provided. In one embodiment of a method, a pre-formed capping wafer is provided, with the capping wafer comprising a conversion material. A wire-bond free LED wafer is fabricated comprising a plurality of LEDs. The capping wafer is bonded to the LED wafer using an adhesive. The LED chips are later singulated upon completion of all final fabrication steps. The capping wafer provides a robust mechanical support for the LED chips during fabrication, which improves the strength of the chips during fabrication. Additionally, the capping wafer may comprise an integrated conversion material, which simplifies the fabrication process. In one possible embodiment for an LED chip wafer, a submount wafer is provided, along with a plurality of LEDs flip-chip mounted on the submount wafer. Additionally, a capping wafer is bonded to the LEDs using an adhesive, and the capping wafer comprises a conversion material. At least some of the light emitted from the LEDs passes through the capping wafer where at least some of the light is converted by the conversion material.
US08329478B2
The present invention relates to a magnetic tunnel junction device and a manufacturing method thereof. The magnetic tunnel junction device includes i) a first magnetic layer having an switchable magnetization direction, ii) a nonmagnetic layer provided on the first magnetic layer, iii) a second magnetic layer provided on the nonmagnetic layer and having a fixed magnetization direction, iv) an oxidation-preventing layer provided on the second magnetic layer, v) a third magnetic layer provided on the oxidation-preventing layer and fixing the magnetization direction of the second magnetic layer through magnetic coupling with the second magnetic layer, and vi) an antiferromagnetic layer provided on the third magnetic layer and fixing a magnetization direction of the third magnetic layer.
US08329477B2
A method and system for releasing active ingredients into the surrounding atmosphere is disclosed. In one embodiment, the dispersion rate of the active ingredient through the membrane is passively regulated by adjusting the porosity of the membrane. In another embodiment, materials with microfluidic channels of various diameters are interposed together so that the configuration of the channels approximates a venturi, thereby improving the flow of the solution through the microfluidic channels. In another embodiment, heat is applied to the top membrane layer to further accelerate the rate at which fluid is dissipated through the membrane structure. Devices incorporating membranes with the disclosed properties are also presented.
US08329473B2
Column which includes a first column with an upper layer of H2SO4 silica gel and a lower layer AgNO3 silica gel and a second column packed with alumina, connected detachably to a lower end of the first column. An oily liquid containing polychlorinated biphenyls, is added to the upper layer and heated. An aliphatic hydrocarbon solvent is supplied to the upper layer, whereby polychlorinated biphenyls captured by the first column are dissolved in the aliphatic hydrocarbon and then flow to the second column. The polychlorinated biphenyls are captured by the alumina which is located near the inlet of the second column, which is then detached from the first column. A hydrophobic solvent is passed through the second column in a direction opposite to the direction in which the aliphatic hydrocarbon was passed, providing an extract containing the polychlorinated biphenyls dissolved in a small amount of the hydrophobic solvent.
US08329472B2
The object of the present invention is to provide a method for suppressing foam formation by identifying a gene involved in foam formation during culture of an acetic acid bacterium and reducing or deleting the function of a protein encoded by the gene, a method for more efficiently producing vinegar that contains a high concentration of acetic acid by using an acetic acid bacterium in which foam formation has been suppressed by the above method, and vinegar produced by the above production method. An acetic acid bacterium with suppressed foam formation was obtained by isolating a gene encoding a protein involved in foam formation during culture of an acetic acid bacterium, then by altering the gene by a modification to reduce or delete the function of a protein involved in foam formation. Further provided is a method for efficiently producing vinegar with higher concentration of acetic acid with the use of the acetic acid bacterium.
US08329467B2
Methods for altering pancreatic and liver cell function are provided, wherein the compositions and methods are based on use of netrin-4 or on altering the activity of netrin-4.
US08329462B2
The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise a self-inactivating configuration for biosaftey and promoters such as the EF1α promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element. These vectors therefore provide useful tools for genetic treatments such as inherited and acquired lympho-hematological disorders, gene-therapies for cancers especially the hematological cancers, as well as for the study of hematopoiesis via lentivector-mediated modification of human HSCs.
US08329455B2
This invention relates generally to systems and methods for digestion of solid waste that simplify solids handling. In certain embodiments, anaerobic methane extraction takes place for a period of time (e.g., from 1 to 4 weeks), after which an aerobic composting process begins in the same chamber. The organic waste remains in place and oxygen (e.g., in air) is forced into the chamber for an additional period of time (e.g., from 2 to 4 weeks). At the conclusion of the aerobic phase, the process yields a rough compost product that is stable and pathogen free. The rough compost can be further processed and blended to create high value engineered soils.
US08329453B2
Disclosed is a compact, microprocessor-controlled instrument for fluorometric assays in liquid samples, the instrument having a floating stage with docking bay for receiving a microfluidic cartridge and a scanning detector head with on-board embedded microprocessor for controlling source LEDs, emission signal amplification and filtering in an isolated, low noise, high gain environment within the detector head. Multiple optical channels may be incorporated in the scanning head. In a preferred configuration, the assay is validated using dual channel optics for monitoring a first fluorophore associated with a target analyte and a second fluorophore associated with a control. Applications include molecular biological assays based on PCR amplification of target nucleic acids and fluorometric assays in general, many of which require temperature control during detection. Sensitivity and resistance to bubble interference during scanning are shown to be improved by use of a heating block with reflective mirror face in intimate contact with a thermo-optical window enclosing the liquid sample.
US08329447B2
The invention provides a naturally occurring strain of Lactobacillus crispatus with advantageous characteristics. The strain colonizes mucosal surfaces, particularly vaginal surfaces. The strain is also capable of rapid growth in a number of conditions and is highly viable after desiccation. Moreover, the strain is capable of preventing and reducing pathogenic infection of vaginal mucosa.
US08329442B2
Disclosed herein are is a novel bacteriophage which has specific bactericidal activity against one or more Salmonella bacteria selected from the group consisting of Salmonella Enteritidis, Salmonella Typhimurium, Salmonella Gallinarum, and Salmonella Pullorum without affecting beneficial bacteria. Disclosed are also compositions, animal feeds or drinking water, cleaners and sanitizers for preventing and treating the infectious diseases caused by Salmonella Enteritidis, Salmonella Typhimurium, Salmonella Gallinarum or Salmonella Pullorum including salmonellosis, Salmonella food poisoning, Fowl Typhoid, and Pullorum disease or for controlling the salmonella bacteria.
US08329440B2
The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same.
US08329429B2
The present invention provides a method of enhanced protein production that comprises the step of expressing a recombinant gene encoding the protein in eukaryotic cells under conditions in which cleavage of the pro-domain of the protein is inhibited or eliminated. Generally the method of the present invention includes the step of inhibiting or altering the cleavage of a pro-domain of a recombinant protein of interest in order to increase the amount of recombinant protein secreted from a eukaryotic cell. Recombinant proteins that can be prepared using the method of this invention include members of the transforming growth factor-β (TGF-β) superfamily, such as bone morphogenetic proteins. Also provided are genetically engineered cells and polynucleotides for performing the method of the invention.
US08329427B2
The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).
US08329423B2
The present invention provides liquid crystal-based devices and methods for bioagent detection. In certain aspects, the present invention is directed to devices and methods utilizing liquid crystals and membranes containing polymerized targets that can report the presence of bioagents including, but not limited to, enzymes, antibodies, and toxins.
US08329422B2
The methods and reagents described in this invention are used to analyze circulating tumor cells, clusters, fragments, and debris. Analysis is performed with a number of platforms, including flow cytometry and the CELLSPOTTER® fluorescent microscopy imaging system. Analyzing damaged cells has shown to be important. However, there are two sources of damage: in vivo and in vitro. Damage in vivo occurs by apoptosis, necrosis, or immune response. Damage in vitro occurs during sample acquisition, handling, transport, processing, or analysis. It is therefore desirable to confine, reduce, eliminate, or at least qualify in vitro damage to prevent it from interfering in analysis. Described herein are methods to diagnose, monitor, and screen disease based on circulating rare cells, including malignancy as determined by CTC, clusters, fragments, and debris. Also provided are kits for assaying biological specimens using these methods.
US08329417B2
Methods that permit the rapid release of one or more analytes from head or body hair or other keratinized structures of an individual (who may previously have ingested one or more of the analytes) are provided. The methods can include contacting the keratinized structure with a reducing agent but not with a proteolytic agent. The methods can further include identification and quantification of the one or more analytes by known analytical techniques such as immunoassays. The described methods do not damage the analyte and do not cause harmful effects on a subsequently-used analyte detection probe (e.g., an antibody).
US08329415B2
The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent includes a glycol and non-specific animal immunoglobulins. Other aspects of the invention include related immunoassays and test kits.
US08329414B2
The purpose of the invention is to provide an antibody which recognizes OPN N-half but does not recognize the full-length OPN, and its use. A monoclonal antibody which is characterized in that it recognizes a protein or polypeptide in which the C-terminal amino acid sequence is YGLR (SEQ ID NO: 1) and it substantially does not recognize a protein or polypeptide which has an amino acid sequence of YGLR outside of the C-terminal, as well as a method for measuring OPN N-half utilizing the said antibody, a method for diagnosing diseases relating to OPN N-half, a method for judging the severity of said disease, and a method for treating said diseases, are provided.
US08329412B2
The invention relates to covalent modification of proteins through their conjugation with other proteins. More particularly, the invention relates to the modulation of such conjugation involving the protein NEDD8. The invention provides compositions and methods for detecting and/or modulating the activation and/or conjugation of NEDD8, as well as compositions and methods for discovering molecules which are useful in detecting and/or modulating the activation and/or conjugation of NEDD8. The present invention arises from the purification and characterization of novel NEDD8 activating and conjugating enzymes.
US08329409B2
The present invention relates to novel methods and compositions useful for detecting whole parathyroid hormone at a physiological level and parathyroid fragments in a mammalian sample. Such detections may be useful to different parathyroid diseases or disorders in a subject, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and optionally one or more of a selection of non-whole parathyroid hormone peptide fragments that may or may not function as a parathyroid hormone antagonists. By either comparing values or using independently the value of either the one or more of a selection of non-whole parathyroid hormone peptide fragments, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states.
US08329408B2
The present invention also relates to biomarkers and the use of biomarkers for the prediction and prognosis of cancer as well as the use of biomarkers to monitor the efficacy of cancer treatment. Specifically, this invention relates to the use of HER-2, EGFR, VEGF, u-PA, p-PAI-1, and soluble forms thereof, as biomarkers for cancer, especially for subjects treated with sorafenib.
US08329405B2
The invention provides an amplification system for the simultaneous detection of mutant alleles, and identification of the specific mutated sequence. A sample is enriched and simultaneously genotyped by the presence of peptide nucleic acids (PNAs) probes in an homogeneous single tube amplification reaction, by detecting the cleavage of a fluorophore quencher from the 5′-end of PCR products and, concurrently, selecting DNA that includes specific mutations relative to wild type, by employing a thermostable endonuclease that will only cleave an amplicon formed on a mutation bearing template strand. Oligonucleotides and kits for conducting the amplification system are also provided.
US08329401B2
The invention is directed to enhanced methods for detecting an analyte of interest in situ, by immunoassay, or by hybridization comprising binding an enzyme-labeled conjugate molecule to an analyte of interest in the presence of a redox-inactive reductive species and a soluble metal ion. The enzyme catalyzes the conversion of the inactive reductive species to an active reducing agent, which in turn reduces the metal ion to a metal atom thereby providing an enhanced means of detecting the analyte via metal deposition.
US08329395B2
The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganisms and isolated polynucleotides containing the mutations are also provided. In addition, methods for detecting a pathogenic microorganism in a clinical sample, assays for identifying an antibiotic, as well as, antibiotics identified by such assays are provided.
US08329383B2
A negative-working lithographic printing plate precursor have an outermost imageable layer that includes an oxygen scavenger and shelf-life stabilizer that is represented by either Structure (I) or Structure (II) below: HOOC—Ar—N(R1)(R2) (I) HOOC—R5—N(R6)(R7) (II) wherein Ar is a phenylene or naphthylene group, R1 and R2 are independently alkyl, alkenyl, alkynyl, phenyl, phenoxy, —R5OH, —CH2—C(═O)—R3, or —CH2—C(═O)O—R4 groups, R3 is hydrogen or an alkyl or phenyl group, R4 is an alkyl or phenyl group, R5 is an alkylene group, R6 and R7 are independently hydrogen or an alkyl, —R5OH, —R5C(═O)—R8, or —R5C(═O)OR9 group, R8 is hydrogen or an alkyl group, and R9 is an alkyl group, provided that the oxygen scavenger has no more than one carboxyl group.
US08329382B2
Imageable elements can be imaged and then processed using a solution containing core-shell particles that are designed to complex with non-coalesced particles in the non-exposed regions of imaged element. A separate development step is not needed, but the non-coalesced particles and complexed core-shell particles can be removed from the resulting printing plate before using the resulting lithographic printing plate for printing.
US08329379B2
Provided is an actinic ray-sensitive or radiation-sensitive resin composition, a resist film formed with the composition, and a pattern-forming method using the same. The actinic ray-sensitive or radiation-sensitive resin composition includes (P) a resin that contains the following repeating units (A), (B) and (C); and a solvent having a boiling temperature of 150° C. or less, (A) a repeating unit containing a group capable of decomposing and forming an acid upon irradiation with an actinic ray or radiation, (B) a repeating unit containing a group capable of decomposing and forming a carboxylic acid by the action of an acid, and (C) a repeating unit containing a carbon-carbon unsaturated bond.
US08329371B2
A non-magnetic toner, including a binder resin; a wax present dispersing in the toner in the shape of a particle; and a colorant, wherein the wax having a particle diameter not less than 2.0 μm and less than 3.0 μm is not less than 20% and less than 40% by number based on total number thereof; the wax has a mode value not less than 1.5 μm and less than 2.0 μm in a frequency distribution of 0.1 μm width; and the following relationship is satisfied: 45
US08329370B2
An image forming apparatus including: a latent electrostatic image bearing member, a charging unit, an exposing unit, a developing unit, a transfer unit, and a fixing unit, wherein the toner contains at least a binder resin and a colorant, the binder resin contains a polyester resin obtained by polycondensation of an alcohol component with a carboxylic acid component containing a rosin compound, the amount of the rosin compound contained in the carboxylic acid component is 5% by mass or more based on the total mass of the alcohol component and carboxylic acid component, and the amount of an abietic acid contained in the toner is 1% by mass or less.
US08329362B2
An extreme ultraviolet (EUV) mask includes a quartz substrate including an absorption region and a reflection region, first and second multi-layered thin films formed on the quartz substrate, and a structure pattern disposed between the first and second multi-layered thin films.
US08329354B2
An ejector and a fuel cell system using the ejector which can improve a control of an ejection pressure of a fluid.The ejector 50 includes a body 60, a nozzle 80, a needle 70, a diffuser 90 which sucks a second fluid by a negative pressure generated by a first fluid ejected from the nozzle 80, and a first, a second and a third diaphragms 100, 110, 120 which are movable in the axial direction against the needle 70. The first diaphragm 100 and the second diaphragm 110 have the same effective area, and an effective area of the third diaphragm 120 is different from those of the first diaphragm 100 and the second diaphragm 110.
US08329351B2
There is provided a fuel cell system capable of suppressing the increase of a control error of a motor. The system includes a fuel cell which generates a power by an electrochemical reaction between a fuel gas and an oxidizing gas, a motor driven by the generated power of the fuel cell, and a control unit which controls the generation state of the fuel cell. The control unit performs high-potential avoiding control to prevent the total voltage of the fuel cell from exceeding a predetermined high-potential avoiding voltage threshold value. In a vehicle velocity region where the control switching of the traction motor is caused, the high-potential avoiding volume is inhibited.
US08329340B2
A negative electrode for a non-aqueous electrolyte secondary battery is provided. The negative electrode includes: an electro-conductive base; a first layer provided on the electro-conductive base; and a second layer provided on the first layer. The first layer includes at least a graphitic material as a negative active material. The second layer includes at least a non-graphitizable carbonaceous material as a negative active material.
US08329339B2
Disclosed herein is a cathode active material based on lithium nickel oxide represented by Formula 1, wherein the lithium nickel oxide has a nickel content of at least 40% among overall transition metals and is coated with a polymer having a melting point of 80 to 300° C. at a surface thereof. A lithium secondary battery having the disclosed cathode active material has advantages of not deteriorating electrical conductivity while maintaining high temperature stability, so as to efficiently provide high charge capacity.
US08329337B2
An electrode and method for preparing the same in which droplets of a first electrode ink composition and droplets of a second electrode ink composition are ejected from an ink jet device onto a base material and the first electrode ink composition contains at least one electrode active material and the second electrode ink composition contains at least one binder material. The resulting electrode is suitable for use in a battery.
US08329327B2
An electrochemical cell in one embodiment includes a first electrode, a second electrode spaced apart from the first electrode, a separator positioned between the first electrode and the second electrode, an active material within the second electrode, and a variable volume reservoir in fluid connection with the active material, such that changes in the volume of the active material cause changes in volume of the variable volume reservoir.
US08329326B2
An electrochemical device 1A has first and second electrode pads 5a and 5b on the upper surfaces 11 of protrusions 3a and 3b, and has first and second electrode pads 7a and 7b on the lower surfaces 13 of the protrusions 3a and 3b. First and second foil electrode terminals 261a and 261b of an electrochemical element 251 are electrically connected to the first and second electrode pads 5a and 5b, respectively. First and second foil electrode terminals 262a and 262b of an electrochemical element 252 are electrically connected to the first and second electrode pads 7a and 7b, respectively.
US08329325B2
A battery pack cooling system may utilize a shroud defining a throat and a body, which may contain a battery pack. An evaporator may be arranged against the battery pack. A liquid coolant delivery pipe may deliver liquid coolant from a reservoir to the throat section with the aid of gravity, a pump, or an ultrasonic misting device. A spray nozzle may also deliver liquid coolant into the throat. When in the throat, liquid coolant mixes with air blown by a fan. Gaps in the battery pack may align with gaps of the evaporator to permit liquid and air to be blown completely through the battery pack and through the evaporator. A refrigeration system including a refrigerant compressor, a condenser and an expansion device work to cool the evaporator to condense, cool and remove liquid coolant from the liquid and air mixture, and deposit it in the reservoir.
US08329324B2
Disclosed herein is a voltage sensing member for sensing voltages of battery cells constituting a battery module, the voltage sensing member including (a) a pair of supporting parts, i.e., a front supporting part and a rear supporting part, mounted to a bottom of the battery module at regions (a front part and a rear part of the battery module) corresponding to electrode terminal connections of the battery cells, (b) a connection part for electrically interconnecting the front supporting part and the rear supporting part, (c) conductive sensing parts having one-side ends coupled to the corresponding supporting parts via wires, each of the conductive sensing parts having a larger contact surface than each of the wires, and (d) a connector mounted on the front supporting part or the rear supporting part for transmitting the sensed voltages of the battery cells to a battery control device, wherein the conductive sensing parts are connected to the electrode terminal connections of the battery cells in a surface contact manner.
US08329319B2
The invention relates to a phase change magnetic composite material for use in an information recording medium, said material comprising a phase change material component, and a ferromagnetic material component, wherein said material exhibits both magnetic effects and phase change effects, and is usable for optical media, phase change random access memory (PCRAM) devices, magnetic random access memory (MRAM) devices, solid state memory devices, sensor devices, logical devices, cognitive devices, artificial neuron network, three level device, control device, SOC (system on chip) device, and semiconductors.
US08329312B2
A superplastically formed structural assembly is provided, as is an associated preform and method for forming such an assembly. The assembly includes a skin member and a support member that are joined to define a space between the members and between the joints. The assembly can be produced by joining the members in a flat configuration, and then forming the resulting preform to a predetermined shape of the structural assembly. The support member defines at least one aperture in communication with the space between the members. Thus, the skin member can be formed by delivering a pressurized fluid through the support member to the skin member, e.g., to superplastically form the skin member against a die that defines a contour surface corresponding in shape to the predetermined configuration of the assembly. The support member can extend in a substantially direct configuration between opposing portions of the skin member.
US08329308B2
A cementitious article and a method of making a cementitious article are disclosed. The cementitious article comprises a cementitious component that comprises a polyvinyl acetate type polymer, a monobasic phosphate, and optionally boric acid. Cementitious articles, such as board, are prepared such that the polyvinyl acetate type polymer, the monobasic phosphate, and optionally boric acid can be present in the cementitious core, and/or in dense layers if present. The concentration of the polyvinyl acetate type polymer, monobasic phosphate, and optionally boric acid in the cementitious article can increase from a central region A to peripheral regions B and C, respectively. In some embodiments, the polyvinyl acetate type polymer is a polyvinyl alcohol and the monobasic phosphate is monoammonium phosphate.
US08329296B2
The invention relates to primary particles of oxide-ceramic material, wherein the primary particles have an average particle size in the range from 10 to 1000 nm and are coated with a chromophoric component, a process for their preparation and their use in particular in the preparation of ceramic moldings and dental restorations. The invention further relates to a suspension based on oxide-ceramic material which contains the primary particles, and a process for the preparation of a ceramic moldings.
US08329290B2
A silicone resin composition containing (i) a silicone resin and (ii) fine metal oxide particles without having a reactive functional group or with a protected reactive functional group on the surface thereof (fine metal oxide particles B), wherein the silicone resin is obtained by carrying out a polymerization reaction between a silicone derivative having an alkoxysilyl group at an end of a molecule and a molecular weight of from 200 to 3000, and fine metal oxide particles having a reactive functional group on the surface thereof (fine metal oxide particles A), and wherein the fine metal oxide particles B are dispersed in the silicone resin (Embodiment 1); a silicone resin.
US08329280B2
A chopped fiber bundle includes a large number of unidirectionally arranged reinforced fibers. The length of each of the reinforced fibers is in the range of 5 to 100 mm. The chopped fiber bundle has a transition segment in which the number of the reinforced fibers increases toward the central part of the chopped fiber bundle in the aligned direction of the reinforced fibers with both ends in the aligned of the reinforced fibers in the chopped fiber bundle being a starting point. The level of a change in total sectional area of the large number of reinforced fibers is not more than 0.05 mm2 per mm in the aligned direction of the reinforced fibers over the whole area in the longitudinal direction of the chopped fiber bundle.
US08329269B2
A tubular film for foodstuff casings, which film is produced from a polymer composition containing a thermoplastic polyester that has a complex shear viscosity η* of at least 3000 Pa·s measured ISO 6721-10:1999 at 240° C. and 0.1 rad/s. Also claimed is a foodstuff casing produced from the tubular film.
US08329260B2
A substrate is implanted with a species to form a layer of microbubbles in the substrate. The species may be hydrogen or helium in some embodiments. The size at which the microbubbles are stable within the substrate is controlled. In one example, this is by cooling the substrate. In one embodiment, the substrate is cooled to approximately between −150° C. and 30° C. This cooling also may reduce diffusion of the species in the substrate and will reduce surface roughness when the substrate is cleaved along the layer of microbubbles.
US08329259B2
An electrostatic painting apparatus for electrostatically painting a door on a vehicle body. The painting apparatus uses a robot arm that opens/closes the door. A high voltage is applied to the robot arm and the amount of any current between an electrode pin on the robot arm and the door is measured to determine the positional relationship between the door and the robot arm.
US08329254B2
Disclosed is a method for producing an ink-jet head which enables the formation of an ink-repellent layer having excellent ink ejection stability, excellent adhesion to a head base material and excellent pressure resistance in a simple manner. The method for producing an ink-jet head is characterized by applying a coating solution comprising a compound represented by Formula (1) and an aqueous dispersion of a fluororesin to an ink-ejecting surface of an ink-jet head to form an ink-repellent layer on the ink-ejecting surface.
US08329252B2
A method is described for the growth of high-quality epitaxial silicon carbide (SiC) films and boules, using the Chemical Vapor Deposition (CVD) technique, which comprises the steps of supplying original species SiH4 and CCl4 into a growth chamber, decomposing at elevated temperatures, producing decomposition product SiH2, SiH, Si, CCl3, or CCl2, producing interaction product HCl, CH3Cl, CH4, or SiH2Cl2, etching by one of the byproducts HCl to suppress Si nucleation, providing main species SiCl2 and CH4 at a cooled insert located on sides of a substrate holder and at a shower-head located on top of the substrate holder, in the growth chamber, with proper Si to C atom ratio and Si to Cl atom ratio, to suppress parasitic deposits, and depositing SiC on a substrate at a proper growth substrate temperature (1500 to 1800 centigrade range).
US08329247B2
A method for producing a multi-layer photonic structure having at least one group of alternating layers of high index material and low index material may include, determining a characteristic property function for the multi-layer photonic structure, determining a thickness multiplier for the at least one group of alternating layers based on a comparison of the characteristic property function to a target profile, adjusting the characteristic property function with the determined thickness multiplier, and comparing an adjusted characteristic property function to the target profile, wherein, when the adjusted characteristic property function does not approximate the target profile, at least one additional group of layers is added to the multi-layer photonic structure.
US08329240B2
A method of improving the flow properties or cold solubility of a milk powder and use of the modified powder in beverage distribution machine for delivering, in particular, cold beverages. The method includes controlling glycation of proteins in the range of 10 to 35% blocked lysine and lactose crystallization between 5 and 50%. The resulting powder also represents an embodiment of the invention.
US08329238B2
Novel cooling compositions having a natural status are object of the present invention. These compositions comprise a combination of menthol, together with a nature identical ingredient and at least one natural extract. They can be added to flavoring compositions to impart cooling sensations devoid of mentholic flavoring notes.
US08329236B2
The present invention relates to a low sodium salt composition and the methods used to make it. The low sodium salt composition includes sodium chloride and a modified chloride salt composition. The modified chloride salt composition includes a homogenous amalgamation of chloride salt, food grade acidulant, and carrier, which does not contain sodium chloride. The low sodium salt composition is made using a two step. The first step includes making a modified chloride salt composition and the second step includes combining the modified chloride salt composition with sodium chloride to form a low sodium salt composition.
US08329227B2
The present invention provides formulas for producing compositions for the structural/functional nutritional support for those who struggle with poor focus, concentration and/or memory. In addition, the present invention provides compositions comprising nutritional/botanical factors helpful to those who subjectively experience transient mental fatigue or poor cognitive function. The compositions of this invention consist primarily of the following ingredients B-complex vitamins, antioxidants, minerals, phosphatidyl serine (PS), choline, dimenthyl-aminoethanol (DMAE), docosahexaenoic acid (DHA), L-pyroglutamic acid, as well as herbal extracts from Bacopa monniera, Vinca minor, and Huperzia serrata. The present invention also relates to the administration of these compounds to alleviate mental fatigue or poor cognitive function.
US08329220B2
The present invention provides stable, self-assembling, biocompatible and biodegradable hydrogel formulations, into which one or more compounds may be incorporated allowing for delayed release or controlled release of the incorporated compounds as the hydrogel is degraded in the body.
US08329217B2
A dosage form that provides a controlled release of at least two different active agents is provided. Particular embodiments include a dosage form that provides therapeutically effective levels of a first active agent and a second active agent in a mammal for an extended period of time following oral administration. An osmotic device containing a bi-layered core is provided. The osmotic device provides a dual controlled release of both drugs from the core. The layers of the core are in stacked, substantially concentric or substantially eccentric arrangement.
US08329197B2
The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
US08329195B2
Provided herein are compositions designed to reduce or prevent pneuomococcal infections, nasal carriage, nasal colonization, and central nervous system invasion. Provided herein is a composition comprising a polypeptide comprising the amino acid sequence of SEQ ID NO: 19 or a variant thereof that can elicit an anti-neuraminidase immune response. Further provided are methods of making and using the compositions disclosed herein. Specifically provided are methods of generating antibodies in a subject comprising administering to the subject an agent or composition taught herein. Also provided are methods of reducing or preventing nasal carriage or pneumococcal infection in a subject comprising administering to the subject a composition taught herein.
US08329192B2
The present invention provides isolated metal regulated polypeptides obtainable from a Campylobacter spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for treating in infection in a subject, for treating a condition caused by a Campylobacter spp., and for decreasing colonization of an animal.
US08329177B2
We found that FIZZ1/RELMα is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELMα was located in the pulmonary vasculature, bronchial epithelial cells, and type II pneumocytes. Recombinant FIZZ1/RELMα protein stimulates rat pulmonary microvascular smooth muscle cell (RPSM) proliferation dose-dependently. Therefore, we renamed this gene as hypoxia-induced mitogenic factor (HIMF). HIMF strongly activated Akt phosphorylation. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 inhibits HIMF-activated Akt phosphorylation. It also inhibits HIMF-stimulated RPSM proliferation. Thus, the PI3K/Akt pathway, at least in part, mediates the proliferative effect of HIMF. HIMF also has angiogenic and vasoconstrictive activity. Notably, HIMF increases pulmonary arterial pressure and vascular resistance more potently than either endothelin-1 or angiotensin II.
US08329175B2
The invention features methods and compositions for treating and preventing angiogenic disorders and endothelial cells disorders using HspA12B antagonist and HspA12B agonist compounds, respectively.
US08329174B2
Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
US08329168B2
Novel thrombin/prothrombin protease/zymogen variants which have anticoagulation activity and methods of use thereof are disclosed.
US08329166B2
Disclosed is a cultured pluripotent animal cell that is prepared from nasal polyps. Also disclosed are methods for making the cell and methods of treating a brain tissue damage or of promoting cerebral angiogenesis, cerebral neurogenesis, stem cell homing to the brain, neurotrophic factor expression in the brain.
US08329159B2
The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
US08329156B2
This invention relates to thermoplastic elastomers comprising at least one silicone ionomer. These thermoplastic elastomers may be reprocessed and/or recycled.
US08329152B2
Agents for temporarily shaping keratin fibers having a very high degree of hold. These agents impart a feeling of providing flexible and conditioned hair while also being pleasant to the touch. Agents according to the invention contain, in a cosmetically acceptable carrier, at least one copolymer A having at least one structural unit according to formula (I), and at least one further structural unit according to formula (II), wherein X+ is a physiologically acceptable cation, and further contains at least one further structural unit according to formula (III) and at least one silicone oil and/or silicone rubber.