US10259154B2
The present disclosure provides a coextruded multilayer film The coextruded multilayer film includes a core component having from 15 to 1000 alternating layers of layer A and layer B. Layer A has a thickness from 10 nm to 1000 nm and includes a beta-propylene-based polymer having a crystallization temperature (T1c). Layer B includes a second polymer having a glass transition temperature (T2g), wherein T1C
US10259144B2
The present disclosure provides a laser sintering apparatus and a laser sintering method. The laser sintering apparatus includes a first laser head configured to output a laser beam at a first power level, a second laser head configured to output a laser beam at a second power level, and a driving device configured to drive the first laser head and the second laser head to move, so as to enable the first laser head and the second laser head to heat an identical region of a to-be-sintered material.
US10259139B2
An extrusion forming apparatus includes an extruding section, a chamber drum, and a forming section. The extruding section kneads a material including a ceramic raw material and extrudes a kneaded material. The chamber drum has a first space portion having a first extruding direction extending portion through which the kneaded material is allowed to flow in an extruding direction, and a second space portion which has a second extruding direction extending portion extending in the extruding direction and a direction changing portion bending from the extruding direction to a downward direction, to allow the kneaded material to flow in the downward direction changed from the extruding direction. The second space portion has a cross section obtained by isotropically decreasing a cross section of the first space portion perpendicular to a flow-through direction of the kneaded material. The forming section has a die to extrude a ceramic formed body.
US10259138B2
An injection mold system for injecting slurry into an internal portion of an injection mold component core is disclosed. The system may include a fill clip for injecting slurry into an internal portion of an injection mold component core including a fill member for injecting slurry into the internal portion of the injection mold component core, and a latch member for removably coupling the fill member with the injection mold component core. The system may also include a fill reservoir for collecting excess slurry from the internal portion of the injection mold component core. The fill reservoir may also redistribute the excess slurry back into the internal portion of the injection mold component core.
US10259111B2
A tool attachment for a handheld power tool that has a housing having a fastening interface includes: an attachment housing on which there is situated a locking unit for locking the tool attachment on the fastening interface of the handheld power tool; a tool receptacle for accommodating an insertion tool; and a hammer mechanism situated in the attachment housing, which hammer mechanism is configured to apply an impact in the axial direction of the tool receptacle on the insertion tool, during hammer operation of the tool attachment.
US10259108B2
An apparatus is disclosed for dismantling a pallet comprising an elongated handle having a free end and an attachment end, wherein the attachment end is coupled with a crossbar having a horizontal axis extending perpendicular to the plane of the handle. The apparatus also has one or a plurality of blades extending rigidly forward in adjustable communication with the crossbar via a notched aperture in each blade for receiving the crossbar, wherein each blade further comprises a lower curved portion, and an upper portion for engaging a board of a pallet, at least one wheel rotatably coupled with said lower curved portion, and means for clamping the blades to the crossbar.
US10259105B2
A jig for assembling a curved surface display device includes: a base station, which is provided with a bearing surface; a support frame provided on the bearing surface; and a bottom surface support plate provided on the bearing surface to support back of the curved surface display device. The support frame is provided with a plurality of corner support pieces to support corners of the curved surface display device, a distance between each of the corner support pieces and the bearing surface is adjustable.
US10259098B2
A polishing apparatus polishes a surface of a substrate by pressing the substrate against a polishing pad on a polishing table. The polishing apparatus is configured to control a temperature of the polishing surface of the polishing pad by blowing a gas on the polishing pad during polishing. The polishing apparatus includes a pad temperature control mechanism having at least one gas ejection nozzle for ejecting a gas toward the polishing pad and configured to blow the gas onto the polishing pad to control a temperature of the polishing pad, and an atomizer having at least one nozzle for ejecting a liquid or a mixed fluid of a gas and a liquid and configured to blow the liquid or the mixed fluid onto the polishing pad to remove foreign matters on the polishing pad. The pad temperature control mechanism and the atomizer are formed into an integral unit.
US10259097B2
An embodiment comprises: a lower plate; an upper plate which is disposed on the lower plate and rotates; a carrier which receives a wafer and is disposed on the lower plate; and a sensor unit for irradiating light to the wafer received in the carrier, detecting light reflected by the wafer, and outputting detection data according to the detection result, wherein the sensor unit rotates together with the upper plate.
US10259094B2
A material removal device for removing material from a substrate includes a holder extending between first and second sides and a grinding wheel supported by the holder and being operable to remove the material from the substrate. The holder has a guide frame at the first side and a support frame at the second side. The guide frame has a first bottom surface and the support frame has a second bottom surface. The first and second bottom surfaces are vertically offset from each other. The grinding wheel has an axle supported by the guide frame and the support frame. The grinding wheel has a grinding surface located below the first bottom surface and above the second bottom surface.
US10259092B2
An apparatus for machining a cylindrical workpiece has a hollow spindle with a driving center on its tip end. The hollow spindle is rotationally journaled within a spindle unit. A tail stock spindle, with a centering center on its tip end, is rotationally supported and axially movable within a centering unit. A shaft-like kelly is non-rotationally and axially movably supported within an inner bore of the spindle. A drive rotates the spindle. Cylinders axially drive the kelly and the tail stock spindle, respectively. The spindle, the tail stock spindle and the cylinders are arranged on the same axial line. The cylindrical workpiece is sandwiched between the driving center and the centering center. An outer circumferential surface of the workpiece is finish machined while rotating the workpiece under a condition where the kelly engages the workpiece within an inner bore of the workpiece.
US10259076B2
A device for manufacturing a layered object includes a container, a vibration unit, and an energy beam irradiation unit. The container includes a stage, a wall surrounding the stage, and a lid. The vibration unit vibrates raw material powder to planarize a face of the raw material powder supplied into the container. The energy beam irradiation unit irradiates part of the raw material powder with an energy beam to form part of the layered object. The lid presses the raw material powder when the vibration unit vibrates the raw material powder. A space is formed between the wall and the lid in the container when the lid is in contact with the raw material powder. The raw material powder is allowed to flow into the space.
US10259068B2
Method of assembling a first thin copper part and a second thin aluminum part, each to be welded using heterogeneous welding, includes placing the ends of the parts so that they face one another and pressing the ends against one another so as to constitute a welding zone extending therebetween; and applying an aluminum alloy by way of filler metal to the welding zone using a low energy welding method in which the electric arc and the meltable filler wire are wider than the combined thickness of the parts, the parts being held so as to maintain the welding zone at the top using a fixing element including at least two rigid blocks of a conductive material whose thickness is between 1 and 2 mm, whose length is greater than that of the parts and whose width is sufficient to hold the parts, and a pressure fixing system.
US10259060B2
A reciprocating tool includes a motor, a crank, a connecting rod, a rod, a tool bit, and a counter weight. The tool bit is mounted such that the action portion is positioned on a side opposite to a side with the rod central axis or the extended line of the rod central axis viewing from the rotational center of the crank. The first eccentric shaft and the second eccentric shaft are disposed such that at a position where the first eccentric shaft causes the rod to reach top dead center (TDC), the second eccentric shaft causes the counter weight to reach bottom dead center (BDC) or a point before the BDC, and at a position where the first eccentric shaft causes the rod to reach the BDC, the second eccentric shaft causes the counter weight to reach a point before the TDC.
US10259052B2
A system for duplicating a master key includes a clamping mechanism for receiving and positioning a master key. The master key defines a major key axis and an intermediate key axis along which a key blade variably extends. The key blade has an upper surface and a minor key axis along a key thickness. A mechanical measurement device includes a probe that deflects along the intermediate key axis during a measurement process. A movement mechanism imparts relative motion along the major key axis between the mechanical measurement device and the master key. The mechanical probe follows the upper surface of the key blade. The mechanical measurement device generates a signal indicative of the deflection of the probe. A processor receives the signal and generates information usable for defining the machining of a duplicate key.
US10259049B2
A system is proposed that is made up of a tool holder 1, a collet 15 with a clamping nut 19, and a tool insert 27, in which the collet 15 and the tool insert are fixed and positioned on various function surfaces within the tool holder 1. Nevertheless, the clamping means are the same, namely a thread on the tool holder 1.
US10259045B2
A method for forming a part includes: forming a first portion of the part at a first level; forming a second portion of the part at a second level; wherein forming the first and second portions includes exposing the first and second levels to a sintering process and portions of the first and second levels to an electron beam; causing a magnetorheological (MR) fluid to move into a passage inside the first and second portions; exposing the first and second portions to a magnetic field causing motion of particles in the MR fluid to move and break up sintered material in the passage; and removing some or all of the sintered material in the passage.
US10259039B2
A method of manufacturing a component that includes providing a core structure, casting a component about the core structure, removing a first portion of the core structure from the cast component, and leaving a second portion of the core structure in the cast component to provide a reduced cross-section in the cast component.
US10259035B2
The invention relates to mold material mixtures containing at least one aluminum oxide in the alpha phase and/or at least one aluminum/silicon mixed oxide, except for aluminum/silicon mixed oxides having a layered silicate structure, as a particulate metal oxide, in combination with refractory mold base materials and a water glass-based binder system. The mold material mixtures are used for the production of molds and cores for the foundry industry.
US10259032B2
Metal foil base material placed on lower blade is first restricted under pressure by lower blade and pad and then cut by a shearing action based on an engagement of lower blade side cutting edge and upper blade side cutting edge. Resin face sheets are fixed to the top surface of lower blade and the pressing surface of pad, the face sheets having a larger friction coefficient than that of these surfaces. By frictional forces imparted by face sheets, metal foil base material is prevented from being dragged and moved by the pressing force of the upper blade prior to cutting. Consequently, the occurrence of “burr”, “roll-up”, and so forth is eliminated thereby ensuring a good cutting quality.
US10259025B2
A method for preparing the iron-based biochar material, the iron-based biochar material prepared there from and a method for controlling the heavy metal pollution in soil using the iron-based biochar material. For the iron-based biochar material of the present invention, by using a method of high-temperature carbonization, a biomass is used as a raw material and an iron-containing compound is add in the process of preparing biochar, wherein iron is incorporated in a specific ratio, to form the iron-based biochar material with a special structure and function. The material has a simple preparation process, low cost and a short production period; the prepared iron-based biochar material has an unique effect on the arsenic-cadmium combined pollution soil remediation, can effectively reduce the bioavailability of arsenic and cadmium in the soil, significantly reduces the arsenic and cadmium contents in the agricultural products planted in the arsenic-cadmium combined pollution soil, and has no toxic and side effects on the crops, is safe to apply and can be applied to the control of arsenic-cadmium combined pollution soil in a large scale.
US10259023B2
Improvements in a processing basket lining system for slide maker-stainer instrument. The utility liner is configured to sit on top of the processing baskets that are customarily occupied/filled with the processing reagents. The probe jackets are shaped to slip in and out without interfere with its capacity to dispense-drain reagents while submerged to the intended reagents in the processing baskets. The liners provide a surface between the processing baskets or probes and the reagents where debris can accumulate as a waste by-product of the process largely in quantities or simply just by the length of use time. The disposable utility lining system, processing basket and probe cover are disposable. The liners are preferably made of plastics. The material of choice is tested not to react with the processing reagent for a period of time, depending on the manufacturer's maintenance requirement.
US10259022B2
An infectious waste treatment system and method for decontaminating infectious waste employ a thermal friction extruder in which first and second interleaved counter-rotatable augers include reverse pitch flight sections that urge waste material in a direction opposite to that of the flow stream and into engagement with the back sides of friction plates. This increases the amount of heat generated by the extruder. The reverse pitch flight sections can be selectively replaced with forward pitch flight sections to control the amount of heat imparted to the waste material by the friction plates.
US10259011B2
A disc for a separating conveyor screen has a disc body with an opening in an axial direction for receiving a shaft. At least one anchoring member of the disc has an anchoring portion projecting into the opening in a radially inward direction and has a positioning portion fitted in a disc body of the disc. The anchoring portion has at least one projection in circumferential sense of the opening for anchoring in at least one recess in an outside surface of the shaft. At least one tensioner is provided for tensioning the anchoring member and the disc body radially towards each other. A separating conveyor screen equipped with such discs is also described.
US10259010B2
A method for curing an automotive coating is disclosed. The method includes applying a first automotive coating to at least one surface; moving a hand-held ultraviolet light source into a booth that has the at least one coated surface; curing the first automotive coating with the ultraviolet light source; moving the ultraviolet light source out of the booth that has the at least one coated surface; applying a second automotive coating to the at least one surface; moving the ultraviolet light source into a booth that has the at least one coated surface; curing the second automotive coating with the ultraviolet light source; and moving the ultraviolet light source out of the booth that has the at least one coated surface.
US10259009B2
A balloon coating method and a balloon coating apparatus are disclosed by which the thickness and/or morphological form of a drug in a coating formed on a balloon can be appropriately set. The balloon coating method can include moving a coating section for applying a coating liquid containing a drug relative to the balloon in the direction of an axis, while rotating the balloon about the axis of the balloon, thereby to apply the coating liquid to an outer surface of the balloon; detecting the distance of a dried part where the coating liquid applied to the outer surface of the balloon has been dried from the coating section; and controlling moving velocity of the coating section relative to the balloon in such a manner that the distance of the dried part from the coating section is maintained at a preliminarily set designated distance.
US10259003B2
A pump assembly cap includes an accumulator reservoir configured for fluid communication with a container through a one-way inlet valve. An actuator including a dispensing passage having a dispensing orifice. A delivery path extended from the one-way inlet valve, through the accumulator reservoir, the one-way outlet valve, and to the dispensing orifice. The delivery path includes a sealed configuration and an opened configuration. In the sealed configuration, the actuator is in a ready position and the accumulator reservoir includes a first volume, the one-way outlet valve hermetically seals the accumulator reservoir, and the one-way inlet valve is closed. In the opened configuration, the actuator is moved to a dispensing position and the accumulator reservoir includes a second volume less than the first volume, the hermetic seal of the one-way outlet is open, and the one-way inlet valve is closed.
US10258995B2
Provided are a solvent separation method, a solvent separation apparatus, and a solvent separation system that make it possible to easily collect a solvent removed from an exhaust atmosphere and that make it possible to easily carry out maintenance of exhaust gas pathways. An impeller placed in a storage space of a casing is rotated to introduce a gas including a volatilized solvent from an inlet of the casing into the storage space, and the volatilized solvent is cooled and devolatilized by a collection face that has been cooled so as to have a surface temperature lower than the temperature of the gas, to thereby separate the solvent from the gas.
US10258993B1
A media shredder system includes a body forming an inner cavity; a punch cutter; a die cutter; and a driver. The punch cutter includes a punch cylindrical body with an outer surface; and a plurality of random oriented protrusions with sharp cutting edges, the protrusions are configured to protrude from the outer surface of the cylindrical body. The die cutter includes a die cylindrical body with an outer surface; and a plurality of dies extending inwardly from the outer surface of the die cylindrical body, the plurality of dies matching the plurality of random oriented protrusions. The driver simultaneously rotate the punch cutter and the die cutter.
US10258985B2
This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced. In another set of embodiments, a fluidic stream may be manipulated in some fashion, for example, to create tubes (which may be hollow or solid), droplets, nested tubes or droplets, arrays of tubes or droplets, meshes of tubes, etc. In some cases, droplets produced using certain embodiments of the invention may be charged or substantially charged, which may allow their further manipulation, for instance, using applied external fields. Non-limiting examples of such manipulations include producing charged droplets, coalescing droplets (especially at the microscale), synchronizing droplet formation, aligning molecules within the droplet, etc. In some cases, the droplets and/or the fluidic streams may include colloids, cells, therapeutic agents, and the like.
US10258980B2
The present invention relates to metal complexes and methods of synthesizing the metal complexes. The invention is further directed to pharmaceutical and/or dietary supplement composition comprising compounds synthesized as described herein.
US10258976B2
Precatalysts of formula I and IV, and processes for the functionalization of SP2-carbons using the same are described herein. The precatalysts comprise a fluoroborate salt protected intramolecular frustrated lewis pair (FLP). The precatalysts are bench stable with improved stability towards moisture and/or air. The precatalysts can be used to generate in situ the corresponding FLP catalyst.
US10258963B2
A stainless steel wire may be platinized using electrophoretic deposition (EPD) method and then may be coated by polyaniline/multiwalled carbon nanotube (PANI/MWCNT) nanocomposite by electrochemical polymerization (EP). The resulting fiber may be used for headspace solid-phase microextraction (HS-SPME) of residual solvents (benzene, toluene, ethylbenzene and xylene, BTEX) in commercial pharmaceutical drugs, followed by gas chromatography-flame ionization detection (GC-FID).
US10258950B2
A method of making a package for a fuel unit, a fuel unit including the package, and a hydrogen generator including one or more of the fuel units are disclosed. The package includes a package strip made by forming apertures in a nonconductive substrate strip, forming conductor sections in a conductor strip, aligning the substrate and conductor strips, bonding the conductor sections to the substrate strip to cover the apertures, and removing non-bonded portions of the conductor strip. A package enclosing a hydrogen generating reactant is formed by securing a segment of the package strip to itself, to one or more other segments and/or to one or more other package components. One or more conductor sections in the package strip are in thermal contact with one or more quantities of reactant composition so heat can be transferred thermally decompose the reactant composition and generate hydrogen gas.
US10258948B2
A nozzle part dropping a slurry and a rotary disk centrifugally spraying the slurry to be dropped from the nozzle part are included. The rotary disk includes a plurality of grooves stretching in a radiation direction at least in a periphery part of a surface on which the slurry is sprayed.
US10258945B2
A mechanical resonant system includes a voice coil actuator, a payload mass (110A,110B), a driver mass (120A,120B,120C) and a frame mass (130A,130B,130C). The voice coil actuator includes a bobbin (160), an electrical conductor (170) and a magnet assembly (180,190). The bobbin is made from a material that is electrically nonconductive. The electrical conductor is coupled to the bobbin. The magnet assembly has a housing (180) and a magnet (190) coupled to the housing. At least a portion of the bobbin (160) and at least a portion of the electrical conductor (170) are configured to be positioned within a gap formed by the magnet (190) and the housing (180). The bobbin and the magnet assembly are configured to oscillate when an alternating current is applied to the electrical conductor. The payload mass (110A,110B) is coupled to one of the bobbin and the housing. The driver mass (120A,120B,120C) is coupled to the other of the bobbin and the housing. The frame mass (130A,130B,130C) is coupled to each of the payload mass and the driver mass. The payload mass, the driver mass, and the frame mass are each independently moveable with respect to one another.
US10258939B2
An apparatus includes a body having a length extending from a first end to a second end. The body defines a bore extending through the entirety of the body and at least one of a plurality of grooves or holes around the bore. The body has a length that is dimensioned to be received entirely within a neck of a container.
US10258919B2
An oxygen separator for generating an oxygen-enriched gas from an oxygen comprising gas, said oxygen separator comprising: a) an oxygen separator device comprising i) a sorbent material for sorbing at least one component of the oxygen comprising gas; and ii) at least two controllable interfaces, comprising a first controllable interface and a second controllable interface, for controlling the communication of gas between the inside and the outside of the oxygen separator device, b) a processor for controlling the oxygen separator such that a plurality of phases are sequentially carried, amongst them a purging phase; wherein the processor is configured to control the at least two controllable interfaces such that a flow of gas is generated between the first controllable interface and the second controllable interface during at least the purging phase, wherein the second controllable interface is located and/or controlled such that it controls the fluidic coupling between the inside of the oxygen separator device and a volume of non-oxygen-enriched gas during the purging phase.
US10258917B1
A system for a vehicle includes a water separator and a particulate filter. The vehicle includes an engine that emits exhaust, and the water separator and the particulate filter are disposed downstream of the engine and receives at least a portion of the exhaust. The water separator separates water from the exhaust, and the particulate filter filters particulates of the exhaust such that the water may be subsequently used, e.g., for potable uses, operation of the engine, etc.
US10258909B2
A work vehicle includes a work implement and an operating fluid tank. The operating fluid tank has a tank body and a strainer. The tank body is for collecting operating fluid for driving the work implement. The strainer is installed inside the tank body and includes a cylindrical filter and a cover member. The cylindrical filter is disposed with an axis extending in a vertical direction. The cover member includes an upper plate part and a cylindrical part. The upper plate part of the cover member covers an upper surface of the filter. The cylindrical part of the cover member extends downward from an outer edge part of the upper plate part and covers an upper side surface part of the filter with a gap between the side surface of the filter and the cylindrical part, while allowing a lower side surface part of the filter to be exposed.
US10258903B2
A method for chromatographically separating a first saccharide from a liquid eluent comprising the first saccharide and a second saccharide by passing the liquid eluent through a bed including a polymeric macroporous alkylene-bridged resin in calcium form.
US10258896B2
A building system includes a plurality of building tiles and/or connecters that are magnetically and releasably connectable to one another. The magnetic building tiles are comprised of a tile frame and a tile panel. The tile frame, by one approach, is comprised of two connectable frame portions or elements having magnets embedded therein. The first frame element and the second frame element are connectable to one another through a snap, clip, or another similar connection mechanism. The first and second frame elements are connectable around or into the tile panel, which is removable from the magnetic building tile. The tile panel or the tile frame has a channel into which the other of the tile panel or tile frame extends to secure the two pieces together. In another approach, the tile frame is a single element and the tile panel may snap or attach thereto, such as, for example, through fasteners or friction.
US10258894B2
An outdoor amusement rocking device having a frame and a support member that together form a curvature saddle-shaped play structure. The amusement device includes a hyperbole paraboloid frame structure defining an interior area and a resilient support sheet material disposed in the interior area of the frame and attached to the frame.
US10258891B2
An input using a pointing device is acquired, and it is determined whether the input using the pointing device is an operation of moving an input position. If it has been determined in the determination of the operation that the input using the pointing device is the operation of moving the input position, an operation direction of the operation of moving the input position is determined. If the determined operation direction corresponds to any one of a plurality of directions determined in advance, a predetermined display target is moved in a direction based on the operation direction, thereby causing the predetermined display target to appear on a display screen. If it has been determined that the operation direction corresponds to any one of the plurality of directions, a common display target is caused to appear, regardless of which one of the plurality of directions the operation direction corresponds to.
US10258889B2
A system, computer-readable storage medium storing at least one program, and a computer-implemented method for representing a resource object in a virtual environment are presented. To begin, a graphical user interface may be provided to a player. The graphical user interface may display a virtual environment that includes the resource object and a game object. A resource production event may be detected. The resource production event may be generated based on a resource production attribute that specifies that a quantity of resource units have been generated. Based on the detected resource production event, at least some portion of the quantity of generated resource units is allocated to the resource pool. Then, responsive to detecting a user initiated game action being applied to the game object, a determinable amount of resource units is removed from the resource pool.
US10258888B2
Gaming systems and methods facilitate integrated real and virtual game play among multiple remote control objects, including multiple remotely-controlled aircraft, within a locally-defined, three-dimensional game space using gaming “apps” (i.e., applications) running on one or more mobile devices, such as tablets or smartphones, and/or a central game controller. The systems and methods permit game play among multiple remotely-controlled aircraft within the game space. Game play may be controlled and/or displayed by a gaming app running on one or more mobile devices and/or a central game controller that keeps track of multiple craft locations and orientations with reference to a locally-defined coordinate frame of reference associated with the game space. The gaming app running on one or more mobile devices and/or central game controller also determine game play among the various craft and objects within the game space in accordance with the rules and parameters for the game being played.
US10258881B2
Methods for tagging content in a video game title during game play executed on a game cloud system, and social sharing methods. One method includes receiving a pause indication during the game play and suspending the game play to hold the video game title in a current frame image, storing the game state, and receiving the tag data that is associated to a location in the current frame image and to a user identifier for the current frame image. The method further includes generating a video recording of the game play having the tag data and generating a mini-game from a portion of the video game title. The mini-game includes a playable portion to enable view of a portion of the video recording for the mini-game and an executable portion to enable the play of game code for the mini-game that is a portion of the video game title.
US10258867B2
The present invention relates to a transformer toy car that automatically transforms the shape to turn a card over to provide the information on the card, if the card is attached to the transformer toy car. The transformer toy car includes: a separable toy car body; and cards adapted to be attached to the underside of the toy car body, wherein if one of the cards is attached to the underside of the toy car body, a portion of the separable toy car body is separated, and a portion of the separated toy car body pressurizes a floor surface, thereby making the toy car body stand up or turn over and thus allowing the underside surface of the card attached to the underside of the toy car body to be exposed to the outside.
US10258864B2
An air cushion for absorbing bounces, including at least one air chamber and one air inlet valve, characterized in that the air chamber has a multiplicity of protrusions in the direction of impact.
US10258862B2
A rotating binding for a snowboard or other recreational equipment to which a user's foot is attached includes a lever having teeth at one end for engaging corresponding teeth in a disk attached to the snowboard or other equipment. Movement of the lever is resisted until an additional movement of the lever is performed in order to unsecure the lever from a secured position in which it engages the teeth within the disk. Some examples of the snowboard or other recreational equipment may include retractable fins that may be extended downward from the snowboard, or secured in a retracted position.
US10258850B2
In one example, a system for fitting golf equipment for an individual can be configured to be used with an electronic device comprising a fitting processor module and a camera. The system can comprise an image analysis module configured to receive image data of at least a portion of the individual and one or more physical indicia proximate to the individual, where the image data can be captured by the camera. The image analysis module can also be configured to recognize one or more reference features of the individual from the image data, and to calculate one or more fitting dimensions between the one or more reference features in the image data. Other examples, devices, and related methods are also disclosed herein.
US10258833B2
Multi-piece golf balls having a multi-layered solid core and multi-layered cover are provided.
US10258817B2
The present invention relates to a spray head for effective fire fighting. The spray head according to the present invention provides a uniform distribution of a fluid, such as pressurized water, over a relatively large area. To achieve this, the spray head comprises a body defining a central axis and further comprising a fixation structure for fixing the spray head to a fluid supply system, a fluid inlet, directing fluid in a first direction, a plurality of outlet holes arranged around the central axis, and a flow path between the inlet and the holes, wherein a first set of holes are located in such a way, that the fluid is leaving the first set of holes in a second direction opposite to the first direction and wherein the body further comprises an arrangement for holding a fire actuation member.
US10258815B1
A collapsible cooking oil fire extinguishing device having a shaft with two rigid support arms for support of a fire resistant material. An automatic locking mechanism with a manual pivot mechanism enables changing the device between a collapsed storage position and an expanded usage position. The rigid support arms extend only partially around the perimeter of the fire resistant material, which enables the fire resistant material to tightly cover a cooking oil fire in a vessel with a handle. The pivot mechanism, automatic locking means, and rigid support arms allow the user to exert downward pressure on the burning vessel, thereby creating an airtight seal, cutting off the supply of oxygen and extinguishing the fire. The spring in the automatic locking mechanism is not under compression in the storage position, which increases reliability and prevents malfunction during long periods of time in the storage position.
US10258813B2
A medical image processing apparatus of an embodiment has acquisitor, a first landmark detector, and an estimator. The acquisitor acquires a perspective image of an object to be treated imaged by an imaging apparatus. The first landmark detector detects a position of a landmark that appears in the perspective image acquired by the acquisitor. The estimator, based on relationship information indicating a relationship between the position of landmark and the position of a target, estimates the position of the search-for location of the object to be treated from the position of the landmark detected by the first landmark detector.
US10258809B2
An antimicrobial treatment system comprises a wearable photoactivation device. The wearable photoactivation device includes a body configured to be positioned on a head of a subject over one or more eyes of the subject. The body includes one or more windows or openings that allow the one or more eyes to see through the body. The body includes one or more photoactivating light sources coupled to the body and configured to direct photoactivating light to the one or more eyes according to illumination parameters. The illumination parameters determine a dose of the photoactivating light that activates, according to photochemical kinetic reactions, a photosensitizer applied to the one or more eyes and generates reactive oxygen species that provide an antimicrobial effect in the one or more eyes, without substantially inducing cross-linking activity that produces biomechanical changes in the one or more eyes.
US10258803B2
Exemplary radio frequency (RF) transmitter circuits that provide power to an implant device are described. An exemplary RF transmitter circuit may be included in an apparatus located external to a patient and may be configured to dynamically adjust an amount of power that is provided to an implant device implanted within the patient.
US10258799B2
An electrical stimulation system for use with a plurality of electrodes implanted within a tissue region comprises a neurostimulator configured for delivering electrical stimulation energy to the plurality of electrodes in accordance with a set of stimulation parameters, thereby injecting a charge into the tissue region, a control device configured for receiving user input to modify the set of stimulation parameters, and controller/processor circuitry configured for, in response to the user input computing a charge injection metric value as a function of a physical electrode parameter and an electrical source parameter for a first set of the electrodes, wherein the electrode set comprises at least two electrodes, comparing the computed charge injection metric value to a safety threshold value, and performing a corrective action based on the comparison.
US10258794B2
Provided is an electrical stimulation device including a first to fourth electrodes, and an electrical stimulation generation section which supplies an electrical stimulation signal to each of the first to fourth electrodes. The electrical stimulation generation section supplies, to the first and second electrodes, an electrical stimulation signal according to a first stimulation pattern, and supplies, to the third and fourth electrodes, an electrical stimulation signal according to a second stimulation pattern. The first stimulation pattern is set so that an electrical stimulation signal for changing stimulation intensity according to a first waveform is supplied to the first electrode, and an electrical stimulation signal for changing stimulation intensity according to a second waveform is supplied to the second electrode, the second waveform being increased and decreased in conjunction with the first waveform. The second stimulation pattern is set so that an electrical stimulation signal for changing stimulation intensity according to a third waveform is supplied to the third electrode, and an electrical stimulation signal for changing stimulation intensity according to a fourth waveform is supplied to the fourth electrode, the fourth waveform being increased and decreased in conjunction with the third waveform. The electrical stimulation generation section alternately performs electrical stimulation of the first stimulation pattern and electrical stimulation of the second stimulation pattern.
US10258788B2
Electrodes having an active region formed of a plurality of layers in which one or more conductive layers is formed of a pattern having a plurality of branches and/or holes (e.g. a grid pattern, a snowflake pattern, etc.) to provide a greater density of edges, so that the ratio of edges in the patterned conductive layer to the perimeter of the active region is greater than a minimum value (e.g., 1.5, 2, 3, 4, 5, 6, etc.). The multiple layers may include the patterned conductive layer and a second conductive layer, which may also be patterned, with a less conductive layer sandwiched between them to achieve a more even charge distribution across the face of the active region than in addition to the greater current density provided by the large number of edges.
US10258784B2
A device for reducing agent penetration at an insertion site is provided that has a porous inner sleeve fluidly connected to a conduit. A vacuum or hydrodynamic source is fluidly connected to the conduit. The device is stabilized by fibroblast in-growth and inhibits bacterial colonization. A device is also provided that has a conduit having a bore and an outer conduit surface. The outer conduit surface is optionally nanotextured to promote fibroblast adhesion and limit bacterial residency. A sleeve is provided in fluid communication with the bore of the conduit, and is formed from materials characterized by a pore matrix through which vacuum or hydrodynamic draw is achieved in a process to promote stabilization and reducing bacterial colonization by draw fluid from an area around the surrounding the site of the device. The sleeve optionally has a distal nanotextured surface.
US10258783B2
Fluid communication devices and supporting structures may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.
US10258778B2
Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.
US10258777B2
Provided is a treatment method and a medical device that can intentionally and locally administer a drug to a lesion area appearing in a narrow blood vessel such as a retinal blood vessel and a spinal blood vessel. The treatment method has an introduction step of introducing a medical elongated body having a drug holder for holding a drug into a living body, an arrangement step of arranging the drug holder at a treatment target inside the living body, and a discharge step of discharging the drug to the treatment target by releasing the drug held by the drug holder.
US10258767B2
A catheter having a catheter shaft and a tip. The catheter shaft includes an inner layer, a first reinforcing layer disposed around an outer periphery of the inner layer, an intermediate layer, a second reinforcing layer disposed around an outer periphery of the intermediate layer, and an outer layer that covers the second reinforcing layer. The tip includes a proximal end portion that extends in an axial direction of the catheter and is joined to at least the intermediate layer and the outer layer, between the first reinforcing layer and the second reinforcing layer. The proximal end portion increases the joining strength between the intermediate layer and the tip and the joining strength between the outer layer and the tip. As a result, it is possible to prevent the tip from easily detaching from the catheter shaft.
US10258762B2
A sleep support apparatus includes a pair of electrocardiographic electrodes that detect an electrocardiographic signal, a photoelectric pulse wave sensor that includes a light emitter and a light receiver and that detects a photoelectric pulse wave signal, peak detectors that respectively detect the peaks of the electrocardiographic signal and the photoelectric pulse wave signal, a pulse wave transit time clock that obtains a pulse wave transit time from a time difference between the peak of the photoelectric pulse wave signal and the peak of the electrocardiographic signal, a sleep state detector that determines that a user's body has not reached a state suitable for sleep when the pulse wave transit time is less than or equal to a certain threshold, and a forearm heater that increases a temperature of a forearm when it is determined the user's body has not reached a state suitable for sleep.
US10258759B2
A bi-level positive airway pressure device includes a housing that has a patient port for connecting to an airway of a patient. Within the housing is a device that generates a positive airway pressure directed towards to patient port. Also within the housing is a system that mechanically detects exhalation (by the patient that is connected to the patient port) that enters into the patient port. Responsive to detecting exhalation, a blocking device occludes the device that generates positive airway pressure, thereby reducing or stopping the positive airway pressure until the system that mechanically detects exhalation no longer detects exhalation, at which time the blocking device is operated to no longer occlude the device for generating positive airway pressure, thereby providing positive airway pressure to the patient port during, for example, inhalation.
US10258756B2
An atraumatic nasal tube for non-invasive respiratory support (NIV-CPAP), having one central tube (5) extending from the nasal bridge, at a distance from the forehead area, to the nasal opening of the patient. The first end of the central tube (5) has an applicator (2) to be fixed to the forehead of the patient for connecting to a hose system coupled to a respiratory machine, and the second end of the central tube (5) comprises nasal connectors (6) protruding in a sickle shape out of the central tube (5) and opening into the nasal opening.
US10258747B2
A method for manufacturing a needle-equipped outer tube includes providing a needle; providing a joint member having a needle insertion hole into which the needle is insertable; providing an outer tube comprising a connection section at a first axial end portion of the outer tube; pressing the joint member, with the needle located in the needle insertion hole, toward the connection section, such that the joint member engages with the connection section of the outer tube; and thermally welding the needle and the joint member, as well as the joint member and the connection section, such that the needle is joined to the joint member, and the joint member is joined to the connection section of the outer tube.
US10258744B2
A pharmaceutical syringe piston having a longitudinal axis includes a body having a central face portion with a first outer circumference and maximum first diameter. A cylindrical sealing portion proximate the central face portion has first and second axial ends and a wall extending therebetween. The wall has a second outer circumference and a second diameter essentially constant along the longitudinal axis between the first and second axial ends of the cylindrical sealing portion and is larger than the maximum first diameter. An annular curved portion has a maximum outer diameter less than the second diameter and connects the first axial end of the cylindrical sealing portion to the first outer circumference. An inert film encloses the central face portion and at least a part of the annular curved portion and has an outer boundary between the first axial end of the cylindrical sealing portion and the first outer circumference.
US10258743B2
Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.
US10258737B2
Disclosed is a skin adherable device for delivering therapeutic fluid into a body of a patient. The device includes a monitoring apparatus, a dispensing apparatus, and a tip for delivering the therapeutic fluid into the body of the patient and for monitoring bodily analyte in the body of the patient. The dispensing apparatus may continuously deliver the therapeutic fluid to the body of the patient and the monitoring apparatus may continuously monitor bodily analytes of the patient.
US10258729B2
A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.
US10258723B2
A breast milk collection device includes a reservoir volume and an adaptor having one end to receive a woman's breast. The adaptor has a drip tube communicating with the reservoir. A source of cyclical application and relief of vacuum force is applied to the woman's breast located in the adaptor for the expression of breast milk. A one-way assembly permits breast milk to enter the reservoir and to submerge the valve element. The valve assembly includes a flexible barrier having an interior hollow chamber in fluid communication with said cyclical source of vacuum force and relief pressure, the flexible barrier fluidly isolating the source from the reservoir. The flexible barrier inflatably expands when relief pressure is applied to the interior of the flexible barrier, the flexible barrier becoming deflated when a vacuum force is applied to the hollow interior of the flexible barrier.
US10258716B2
Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
US10258713B2
Systems and methods for managing scent in an environment include disposing scent diffusion devices within the environment, wherein the diffusion devices comprise a communications facility that enables transmitting signals to and receiving signals from a non-fragrance dispensing, wide-area network gateway device that receives communication and control functions from a remote computer for distribution to the plurality of scent diffusion devices. A sensor in the environment transmits sensor data to the remote computer. A scent parameter for scenting the environment is received at the remote computer. Diffusion of a liquid from the scent diffusion devices is controlled by the network gateway device the to achieve the scent parameter, wherein controlling includes setting or adjusting an operation parameter of one or more of the scent diffusion devices in response to the sensor data.
US10258711B2
A removable replaceable cartridge for use with a liquid diffusing device. The cartridge includes a venturi, a conduit extending to the venturi, a mixing area and an outlet path for atomizing and dispersing a liquid within the cartridge. A diffusion device including a removable replaceable cartridge received within a housing. The housing includes a source of compressed gas which is directed into the cartridge. A venturi head with a unitary body for use with a diffusion device.
US10258710B1
A refill for dispensing a volatile material includes a bottle having a body defined by at least one sidewall and a neck extending outwardly from the at least one sidewall. The neck includes a rim at an upper end thereof, the neck being defined by an inner surface, a top surface, and an outer surface. The refill further includes a plug and a wick having a first end positioned within the bottle and a second end extending out of the bottle, the wick further defining a longitudinal axis. The plug is coupled to the neck of the bottle, the plug retaining the wick within the bottle. At least a portion of the inner surface of the rim is tapered at an angle of between about 2 and about 9 degrees with respect to the longitudinal axis.
US10258709B2
A scent diffuser (e.g., air freshener) configured to automatically circulate fragrant air throughout a surrounding environment comprises a powered air circulator configured for circulating air and a fragrance composition throughout the surrounding environment, and a solar cell positioned within a support face of the air circulator. The support face is configured to secure the scent diffuser relative to a support surface and has an open portion configured to allow light to contact the solar cell. The air circulator may comprise a centrifugal fan positioned within the housing and configured to draw air through intake apertures in sidewalls of the housing and to exhaust air and fragrance through an outflow aperture of the housing.
US10258702B2
A water-absorbent carrier for moist heat sterilization can be used in a narrow space and does not have a risk of generating foreign matter. The water-absorbent carrier is obtained by embedding a water-absorbent substance in a synthetic resin. The water-absorbent carrier can be manufactured by impregnating the water-absorbent substance with a water-soluble substance, drying the water-absorbent substance, embedding the water-absorbent substance in a thermoplastic synthetic resin, and washing the water-absorbent substance to remove the water-soluble substance. Alternatively, the water-absorbent carrier can be manufactured by dispersing a water-insoluble synthetic resin in a dispersion medium, mixing the water-absorbent substance in the dispersion medium, pouring the mixture into a mold, and volatilizing the dispersion medium. A medical article to be sterilized includes the water-absorbent carrier packaged in a closed space. Moist heat sterilization (autoclave sterilization) of the medical article can be performed at a moist heat temperature exceeding 100° C.
US10258691B2
The present invention includes compositions and methods for preventing one or more cardiac channelopathies or conditions resulting from irregularities or alterations in cardiac patterns caused by an active agent or a drug in a human or animal subject comprising: an amount of a lysophosphatidyl compound adapted for oral administration effective to reduce or prevent one or more cardiac channelopathies or conditions resulting from irregularities or alterations in cardiac patterns caused by the active agent or drug. Such compositions may further comprise a monoglyceride, a free fatty acid or a combination of the foregoing, including, e.g., a eutectic mixture.
US10258673B2
The invention relates a pharmaceutical composition containing botulinum toxin and a mucopolysaccharide uses thereof with increased pharmacological activity and long lasting botulinum toxin effect.
US10258672B2
A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTPσ.
US10258669B2
A group of polypeptides and a complex formed by the polypeptides and human serum albumin, a method for improving the solubility of the group of polypeptides in a salt solution by combining the polypeptides with human serum albumin, a method for preparing the complex formed by the group of polypeptides and human serum albumin, and an application of the group of polypeptides and the complex formed by the polypeptides and human serum albumin in the preparation of drugs for suppressing tumor metastasis and treating leukemia are described.
US10258653B2
Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
US10258651B2
A method of generating neural and glial cells is provided. The method comprising growing human stem cells under conditions which induce differentiation of said human stem cells into the neural and glial cells, said conditions comprising the presence of retinoic acid and an agent capable of down-regulating Bone Morphogenic Protein activity.
US10258647B2
The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
US10258644B2
A method for preventing and/or treating a disease associated with increased interleukin-1β and/or interleukin-6 and/or interleukin-8 activity and/or disease, in which a reduction in the activity of interleukin-1β and/or interleukin-6 and/or interleukin-8 is beneficial for healing includes utilizing a silicon-containing, biodegradable material containing a polyhydroxysilicic acid ethyl ester compound, with the proviso that wound defects including chronic diabetic-neuropathic ulcer, chronic leg ulcer, bedsores, secondary-healing infected wounds, non-irritating, primary-healing wounds, ablative lacerations and/or abrasions, are excluded from said disease that is prevented and/or treated with the silicon-containing, biodegradable material.
US10258641B2
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
US10258633B2
The present invention relates to a method for inhibiting fibrosis that occurs in an organ where the farnesoid X receptor (FXR) is expressed. This method involves the step of administering a high potency, activating ligand of FXR in an effective amount to a patient who is not suffering from a cholestatic condition. The invention also provides pharmaceutical compositions containing an effective amount of an FXR ligand and kits for dispensing the pharmaceutical compositions.
US10258627B2
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
US10258621B2
Certain adjunctive therapies comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent for treating HIV-related disorders are provided herein. These disorders include AIDS dementia complex, AIDS-induced encephalopathy, HIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment, minor neurocognitive disorder, minor cognitive motor disorder, vacuolar myelopathy, peripheral neuropathies, and polymyositis. Also provided are pharmaceutical compositions comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent.
US10258616B2
The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain.
US10258612B2
Disclosed are methods and compositions for treating or preventing a disease or disorder responsive to a decrease in baseline mitochondrial iron in a subject in need thereof. The methods typically include administering a pharmaceutical composition comprising a mitochondrial permeable iron chelator to the subject.
US10258609B2
The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis, hypercholesterolemia, low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia, etc. which comprises (a) a compound represented by the general formula (1) (in the formula, each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor.
US10258608B2
The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
US10258606B2
The present invention concerns the use of methods for evaluating β-adrenergic receptor targeting agent treatment for a patient, particularly one with a heart condition. In general, the disclosed methods entail determining the presence or absence of one or more polymorphisms in an endothelin gene system member. Based on the results of this determination, a β-adrenergic receptor targeting agent may be prescribed, administered or a treatment regimen altered, including the administration of a β-blocker. Accordingly, methods of treatment are also described.
US10258595B2
A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.
US10258594B2
Disclosed is a semiochemical composition including methyl palmitate, methyl linoleate, methyl oleate methyl stearate, methyl laurate, methyl myristate, salts thereof, derivatives thereof, isomers thereof and/or structural analogues thereof that have an appeasing effect in cats and/or also effects social facilitation in cats, and an acceptable vehicle. Solutions such as spot-on formulations of long duration are also encompassed. Methods to effect appeasing in a cat and/or social facilitation in cats are also disclosed.
US10258585B2
Disclosed herein are formulations containing carbidopa and optionally levodopa, arginine, and other components that have reduced levels of impurities and toxins, particularly degradation productions. Also disclosed herein are methods of treatment diseases or conditions relating to a loss of dopamine or dopaminergic neurons using such formulations, methods of making such formulations, and kits that include such formulations.
US10258584B2
Disclosed is a pregabalin sustained-release preparation, wherein the sustained-release tablet contains a pharmaceutically active ingredient containing pregabalin or a salt or hydrate thereof, a gel framework material containing alginic acid, and a swellable material containing polyoxyethylene.
US10258576B2
The present invention relates to a particulate material and a solid dosage form notably tablets comprising a regularly shaped calcium-containing compound such as a calcium salt as a therapeutically and/or prophylactically active substance and a pharmaceutically acceptable sugar alcohol such as, e.g., sorbitol and/or isomalt that has a micro structure as evidenced by SEM. The invention also relates to a process for the preparation of the particulate material and solid dosage form. The process involves agglomeration of the calcium-containing compound and the pharmaceutically acceptable sugar alcohol by means of roller compaction. The particulate material obtained by roller compaction is suitable for use in the further processing of the particulate material into e.g. tablets such as chewing tablets.
US10258573B2
A method of preparing an inhalable insulin suitable for pulmonary delivery includes: dissolving an insulin raw material in an acidic solution to form a dissolved insulin solution; titrating the dissolved insulin solution with a buffer solution to form a suspension comprising micronized insulin particles; and stabilizing the micronized insulin particles.
US10258564B2
The present invention relates generally to compositions and methods of using the same. A first aspect of the present invention comprises a composition comprising a first viscosity increasing agent; at least one polyhydric alcohol; at least one buffering agent; at least one preservative; a second viscosity increasing agent; at least one organic solvent; at least one humectant; at least one active pharmaceutical ingredient; and water, wherein the composition is buffered to a pH of about 3 to about 11.
US10258556B2
Disclosed is related to an anti-aging peptide, which has an amino acid sequence of ProAspSerThrGluAlaLys (SEQ ID NO: 1). Also provided are anti-aging compositions comprising the peptide and personal care methods of using the peptide.
US10258553B1
A hair strengthening conditioner formulation for application to human or animal hair for the purpose of strengthening and improving the hair. The present invention is for external application but may also be used in combination with dietary supplement compositions. The present hair strengthening conditioner comprises a proprietary mixture of a number of compounds as described in the tables and the claims.
US10258543B1
A device is provided for unclogging an enteral tube including a first length of tubing, the distal end of which is fitted with a connector for connecting to an enteral feeding tube and the proximal end of which is fitted with a connector that is not compatible with an enteral feeding tube. An anti-reflux valve is situated in the first length of tubing and allows fluid flow only towards the distal end thereof. A second length of tubing has a proximal end connected to the first length of tubing at a position between the proximal end of the first length of tubing and the directional valve. A pressure relief valve is situated in the second length of tubing. A method is provided for utilizing the device to clear a clogged enteral tube.
US10258527B2
A latticed patient-hoisting device for a hospital bed and methods of its use for lifting, moving, turning and positioning of hospital patients. Embodiments of the device have a plurality of vertical and parallel straps running parallel to the patient's body from head to feet and a plurality of horizontal straps perpendicular to the vertical straps. The ends of the horizontal straps are removably attached to one or more rails of a hospital bed by a loop. The device is placed under a patient, and the patient is moved by drawing one or more ends of one side of the horizontal straps and attaching those ends to one or more rails on the same side of the bed. In embodiments, one or more horizontal straps may be detached from a rail or repositioned along it to provide access to a particular area of the patient's body for patient care.
US10258523B2
Apparatus and methods for turning a patient onto their side without having to place anything under the patient's torso in order to turn the patient are provided. This disclosure provides apparatus and methods for turning a patient with these apparatus without having to place anything under the patient's torso. Certain embodiments provide apparatus specifically designed to enable a caregiver to turn a patient without the assistance of a second person to hold them in place.
US10258517B1
A fluid distribution material for use in an absorbent article includes a formed film layer having first and second sides and a basis weight of between about 10 gsm and about 25 gsm, and a nonwoven layer having a basis weight of between about 10 gsm and about 15 gsm and laminated to the formed film layer. The formed film layer includes a plurality of apertured protuberances arranged in a pattern having 10 to 40 protuberances per linear inch. Each of the protuberances includes a continuous sidewall extending from the first side, and the second side has a plurality of apertures aligned with the plurality of protuberances, and land areas in between the apertures. The nonwoven layer includes a plurality of fibers attached to the formed film layer at the land areas. The material has a rewet value of less than 0.075 grams in accordance with the Rewet Test Method.
US10258509B2
An in-ear noise dosimeter in the form of an earplug which senses sound in the ear canal using an eartip which has a sound delivery channel that couples sound at the end closest to the eardrum to an earplug microphone. The earplug can communicate wirelessly with a remote data collection and processing system. A dock unit for storing the earplugs when not worn can compensate for differences in unoccluded-ear versus occluded-ear responses by an acoustic compensator. An electronic compensation filter can be modified by a proximity switch in the earplug which changes state when the earplug is worn in the ear versus stored in a dock unit. The dosimeter can also have a temperature sensor for sensing human body temperature and remotely-located wireless LEDs used to alert the user of high noise dosage. Data can also be downloaded from the earplug using a reader unit.
US10258504B1
A method of repairing a detached retina includes removing sub-retinal fluid from a location within the eye between the retinal tissue and an underlying support tissue, inserting a biocompatible elastomeric patch having encapsulated ferromagnetic particles into an interior of the eye through an incision of a sclera of the eye, positioning a magnetic source adjacent to an exterior surface of the eye such that the magnetic source is aligned with the detached retinal tissue, and drawing the removable elastomeric patch toward the detached portion of the retina with the magnetic source such that the detached retinal tissue is substantially maintained against underlying support tissue along an inner eye wall by magnetic attraction between the encapsulated magnetic particles of the removable elastomeric patch and the magnetic source.
US10258503B2
An ocular implant system including an ocular implant sized and shaped to be inserted at least partially into an eye; a carrier member with a shell having a central channel extending at least partially through the shell from a proximal end towards a distal end of the shell. A guide sleeve removably attached within at least a first region of the central channel of the shell and defining a proximal port into the central channel that is accessible from the proximal end of the shell. An implant holder removably attached within at least a second region of the central channel of the shell adjacent to a distal end of the guide sleeve and having a pair of graspers adapted to releasably secure the implant at a distal end of the implant holder. Related devices, systems, and/or methods are described.
US10258498B2
The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulphur, and combinations thereof; R2 and R3 are independently hydrogen or C1-6alkyl group; R4 and R5 are independently hydrogen, C1-6alkyl group optionally substituted with amino, mono- or di(C1-6alkyl)amino, or with 5 to 24 membered optionally fused heterocyclic ring attached by nitrogen and optionally comprising additional 1 to 3 N, O, S heteroatoms and optionally substituted with C1-6alkyl group or C1-6 alkoxy group; R6 is C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-6alkyl or arylC1-6alkyl group; and stereoisomers including enantiomers, diastereomers, racemic mixtures, mixture of enantiomers and combination thereof, as well as polymorphs, pharmaceutically acceptable salts, solvates, esters and prodrugs thereof for use in the therapeutic or prophylactic treatment of a disorder mediated by heat shock proteins.
US10258479B2
Various devices, methods, and systems to implant and secure a fusion cage or intervertebral prosthesis during treatment of spinal injury or disease are provided. In various embodiments, such devices may comprise an instrument assembly having a body comprising a head, a shaft, and a handle; an insertion stop; and an intervertebral device retainer. Various embodiments also may comprise an impactor assembly comprising a housing; a bit comprising a head, a shaft, and a coupler; a transmission comprising a housing, a cam, a cam follower, a collet, and a driveshaft; and the motor. In various embodiments, the impactor assembly may be deployed with adjustments for the frequency, displacement, and force of impulses delivered to an anchor for the intervertebral device.
US10258476B2
A prosthetic knee with an artificial ACL/PCL. The prosthetic knee includes a femoral component and a tibial component. The artificial ACL/PCL connects the femoral component and the tibial component and includes an anterior cruciate ligament portion connecting an anterior anchor point on the tibial component to a posterior anchor point on the femoral component, and a posterior cruciate ligament portion connecting a posterior anchor point on the tibial component to an anterior anchor point on the femoral component. The artificial ligament may be provided as single length of material and may be pre-assembled into an ACL/PCL module having portions that may be inserted into at least one of the femoral component or the tibial component. A system is also provided for total knee replacement that includes a selection of femoral components, tibial components, and one or more ACL/PCL modules of varying sizes.
US10258469B2
A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure around which the valve is disposed in a collapsed condition. A sheath structure surrounds the collapsed valve, but can be moved relative to the valve to uncover it for expansion at the desired implant site in the patient. The sheath structure may be variously mounted and moved to deploy the valve in various ways. For example, the sheath structure may include multiple parts, each of which can be moved separately to separately deploy various parts of the valve. The apparatus may have other aspects, such as the ability to reverse deployment of the valve, the ability to pass other instrumentation through the valve delivery apparatus, the ability to be smoothly withdrawn from the patient after deployment of the valve, etc.
US10258467B2
A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve.
US10258462B2
An accommodating intraocular lens implant is provided that includes a bowl-shaped posterior lens unit, which comprises a posterior lens, and has an inner surface; an anterior floating lens unit, which comprises an anterior lens; and a plurality of levers, which (a) are in jointed connection with the anterior floating lens unit and the posterior lens unit, and (b) are arranged to move the anterior floating lens unit toward and away from the posterior lens unit, in an anterior-posterior direction. The lens implant is shaped such that the inner surface limits posterior motion of the anterior floating lens unit.
US10258450B2
There are disclosed various embodiments of surgical tacks for use in surgical procedures. The tacks generally include a head and a barrel portion extending distally from the head. Preferably, the head and the barrel portion define a throughbore for receipt of a drive instrument. A thread on the head is provided to engage threads in the installation tool. A tissue thread is provided on the barrel portion to engage tissue. Distal and proximal surfaces of the tissue thread may be oriented at various angles relative to the barrel portion. There is also disclosed an insertion instrument to insert one or more tacks as well as a method of use. There is further disclosed a model device for use in explaining the operation of the instrument.
US10258445B2
An injection apparatus for injecting a medicament into a patient, the injection apparatus has a stationary head and a movable head that is movable with respect to the stationary head. A needle is attached to a needle holder that is held by the movable head and by the stationary head. When the movable head is urged rearwardly, a front edge of the needle moves forwardly with respect to a front face of the movable head.
US10258443B2
A brush head assembly (100) including: a hard platen (24); a plurality of bristle tufts (21), each of which includes a plurality of bristle strands having a proximal end (23) and a free end (25); and an elastomeric matrix (30) bonded to the hard platen, where each of the bristle tufts is bonded directly to the elastomeric matrix without a retention element. A brush head assembly (100) includes: a hard platen (24) with a plurality of bristle tuft holes (28); a plurality of bristle tufts (21), each of which includes a plurality of bristle strands having a proximal end (23) and a free end (25), where each of the plurality of bristle tufts are inserted into a respective one of the bristle tuft holes; and an elastomeric matrix (30) that at least partially encompasses the hard platen and the proximal end of the bristle tufts.
US10258422B2
To arrange surgical end effectors used in minimally invasive surgery, the disclosure provides an instrument holder which can be arranged inside the body of the patient. An instrument holder of this kind has a base part having multiple receptacles. The volume of the base part can be varied for the purpose of inserting the base part into the human body, and removing it therefrom, by way of a trocar. A method is also provided for arranging an instrument holder for surgical end effectors used in minimally invasive surgery inside the patient body.
US10258407B2
An electrosurgical generator includes an electrosurgical energy output configured to deliver electrosurgical energy to a bipolar end effector assembly in a conductive fluid environment for treating tissue. A controller having a processor is configured to control a waveform of the electrosurgical energy such that the waveform oscillates between a cut phase for initiating and sustaining tissue cutting, wherein the waveform includes a cut energy greater than the energy needed to create and sustain arcing, and a hemostasis phase, for desiccating/coagulating tissue, wherein the waveform includes a hemostasis energy less than the energy needed to sustain arcing.
US10258402B2
A bone plate is asymmetric and includes a straight body and a cross arm. The plate has first and second sides, each with the same structure. The body and cross arm include nodes separated by deformable bridges. Each node defines a screw hole, and wings extending laterally therefrom. The wings taper in thickness between the first and second sides. Screw holes are threaded into the nodes. Each of the first and second sides of the body and cross arm define longitudinal channels in the nodes. The plate can be shaped to the bone by deformation at the bridges or removal of portions of the plate at bridges. A pair of benders, each with clamp bracket and clamping bolt threadedly coupled within a threaded hole of the bracket, is also provided for shaping the plate.
US10258400B2
Various forms of a cable fixation device, instrumentation, kit, and methods useful for repairing the skeletal system are introduced. The system utilizes a clamp housing fixing a head end of a surgical cable therein. In an operative configuration the cable is looped around a damaged bone segment and reentered through a lock aperture in the clamp housing then through a multi-part collet and lock cap residing within a lock aperture. The cable loop and each aforementioned component comprise a central axis aligned within a single plane. A sliding interface situated between the lock cap and collet prevent twisting of the surgical cable. The locking mechanism is non-destructive to the cable despite repeated unlocking and relocking of the fixation device. The axis for tensioning of the cable is coincident with the locking axis. A cerclage inserter instrument is disclosed.
US10258398B2
A device including a first member extending along an axis between a first end and a second end. The first end includes a first portion spaced apart from a second portion by a gap extending parallel to the axis. An inner surface of the first portion and an inner surface of the second portion defining a cavity. A pivoting member is movably disposed in the cavity and includes an inner surface defining a passageway. A second member is disposed within the passageway. The pivoting member is movable between a first orientation such that the gap has a first width and the pivoting member is rotatable to a selected trajectory relative to the axis and a second orientation such that the gap has a second width that is less than the first width and the second member is fixed in the selected trajectory. Methods of use are disclosed.
US10258395B2
A bone plate locking mechanism and methods for utilizing same are disclosed. A bone plate in accordance with the present invention includes a bone screw hole having a plurality of first lips and a plurality of second lips. The first lips are closer to the upper surface than the second lips and the first and second lips are offset around the bone screw hole.
US10258389B2
Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer or member having an unexpanded configuration and an expanded configuration, wherein the expandable member in an expanded configuration has a size, volume and/or shape configured for positioning between the spinous processes of adjacent vertebrae in order to distract the vertebrae relative to each other. The systems include one or more expandable members and a mechanical actuation means for expanding the expandable member. The methods involve the implantation of one or more devices or expandable spacers.
US10258381B2
An end cap is provided comprising a head with a tool engagement portion and a shaft with a tip, wherein the shaft comprises a threaded conical portion starting from the tip and extending in a direction to the head. The thread may be provided with a constant pitch, i.e. with a constant distance between the turns of the thread.
US10258373B2
Embodiments include a fiducial deployment system. A fiducial may include dimples to enhance echogenicity and/or to provide for engagement with a delivery cannula or stylet. The needle system may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time, when the fiducials are coaxially disposed around a central deployment member that may be embodied as a delivery cannula or stylet. In certain embodiments, echogenic placement of fiducials may present certain advantages. An elongate structure may be included that is configured to distally advance fiducials along the deployment member.
US10258365B2
A tissue-removing catheter includes a cutter having an axial cavity and an opening extending from the axial cavity through the cutter to allow tissue removed from the body lumen by the annular cutting edge to pass proximally through the opening. A cutter driveshaft defines a tissue-transport passage extending longitudinally therein and in communication with the axial cavity of the cutter. A screw blade extends longitudinally within the tissue-transport passage and includes an external helical thread for transporting removed tissue proximally within the tissue-transport passage as the screw blade rotates about its axis. The cutter driveshaft having a distal end portion operatively coupled to the cutter for driving rotation of the cutter.
US10258358B2
Catheter-delivered endovascular medical devices are described. The devices may include a pull wire connected to a proximal body and a distal body, which may be formed of a basket or other framework that has a plurality of cells. The distal body may move/articulate proximally relative to and toward the proximal body. Methods of using and making the devices are also described.
US10258353B2
The invention relates to a surgical assembly for the implantation of an implantable device in a cavity formed in an osseous structure, comprising abase template intended to be fixed to the osseous structure and a plurality of interchangeable templates intended to be successively coupled to the base template, each of the interchangeable templates having at least one through opening to be used for guiding of a tool to form the cavity in the osseous structure and/or position of the implantable device into the cavity.
US10258346B2
A surgical clip applier is provided including a housing; a pair of handles; a channel assembly extending from the housing; a clip carrier disposed within said channel assembly and defining a channel and a plurality of windows; a wedge plate slidably disposed within said channel assembly and being operatively connected to said handles, said wedge plate including a plurality of apertures formed along a length thereof; a plurality of clips slidably disposed within said channel of said clip carrier; and a clip follower slidably disposed within said channel of said clip carrier at a location proximal of said plurality of clips. The clip follower is configured and adapted for selective engagement with said windows of said clip carrier and said apertures of said wedge plate to distally urge said plurality of clips relative to said clip carrier upon a distal advancement of said wedge plate.
US10258345B2
A polymeric, surgical clip is provided for clamping a blood vessel between two legs. A hook section of the clip comprises, in some embodiments, a sharpened forward edge and/or a sharpened rearward edge for penetrating connective tissue adjacent a vessel before closing the surgical about a blood vessel. The upper leg of the surgical clip may comprise an oblique flank for disposing over the one or more edge of the hook section, preventing damage to soft connective tissue surrounding the surgical clip postoperatively.
US10258340B2
The introducer sheath can be loaded onto a vasoocclusive device after removal of the vasoocclusive device from a microcatheter, to permit the vasoocclusive embolic coil assembly to be used again during a clinical procedure. The sheath includes a hollow, elongated tubular member with a longitudinal slot formed in the upper wall of the elongated tubular member and extending along the length of elongated tubular member. The upper wall of the elongated tubular member adjacent to the slot has an angled configuration to accept the vasoocclusive device. The sheath may include wing members extending outwardly from the angled configuration on the outside surface of the hollow, elongated tubular member to facilitate insertion of the vasoocclusive device into the sheath. The elongated tubular member may also consist of a segment with no slot attached to a flexible pusher member to facilitate initiation of loading of the vasoocclusive device into the sheath.
US10258335B2
A dispensing device configured to operate with an adhesive backed mesh and backing film for tissue bonding is disclosed. The dispensing device provides for low-friction, low force pay-out of a desired length of an adhesive backed mesh to a wound site. The device prevents or eliminates distortion of the mesh prior to application to the wound site, and includes means for reducing or eliminating binding during use. The dispensing device is configured to operate in a “forward” mode (substrate to which mesh is applied passes beneath applicator after mesh is applied) to provide essentially an unobstructed view of the wound site during use.
US10258331B2
An apparatus for affecting tissue includes an end effector configured to interact with a tissue. The apparatus further includes a surgical instrument that includes one or more drivetrains configured to drive a plurality of gear components in order to perform operations of the surgical instrument, and one or more vibration sensors positioned relative to the one or more drivetrains of the surgical instrument to sense and record vibration information from the one or more drivetrains of the surgical instrument, wherein the one or more vibration sensors are configured to generate an output signal based on the vibration information for comparison to predetermined threshold values to determine a status of the surgical instrument.
US10258322B2
A device is disclosed that can pierce and hold tissue and then pass suture through tissue. The device can have a shuttle that can removably attach to a suture and jaws that can be rotatably opened and closed with respect to each other. A method for using the device to repeatedly pass the suture through the tissue without removing the suture or device from the target site is also disclosed.
US10258316B2
A biopsy system comprises an introducer, a biopsy device having a needle, and a marker applier. The introducer may include a closed distal tip, a lateral aperture, a proximally facing interior wall, and a ramp that guides the closed distal end of a marker applier up and into abutment with the wall as the applier is fed into the introducer. The needle of the biopsy device includes a blunt distal end and features providing clearance for the ramp as the blunt distal end is brought into abutment with the wall when the needle is fed into the introducer. The introducer may alternatively include an open distal end having resiliently biased leaves that bear against an inserted biopsy device needle. In some other versions, a fin projects laterally from the closed distal end of a marker applier, spacing the distal end away from a sidewall region of the introducer cannula.
US10258313B2
An ultrasonic intracranial sonothrombolysis pressure amplitude is pre-quantified by using an ultrasound-scanner control unit (110) having an increasing and/or decreasing mode and designed for: with respect to a current mode, interrogating a blockage site iteratively so as to progressively and respectively increase or decrease a pressure amplitude of ultrasound being emitted to the site at which bubbles (144) for oscillating that is caused by the emitted ultrasound are present; iteration to iteration, deriving, from echoes of the emitted ultrasound, a magnitude of an energy of a signal; and automatically identifying, for the quantifying, an iteration that, in comparison with a just-previous iteration, fails to increase the magnitude. The interrogating may span a region that contains or goes through: the obstruction; another part of the blood vessel; and bubble circulation within a neighboring vessel and a neighboring capillary (136). The deriving can be based on an ultraharmonic signal, with band-pass filtering being utilized to extract the ultraharmonic signal from returning signals differenced to remove stationary content.
US10258309B2
Various embodiments of an eye imaging apparatus are disclosed. In some embodiments, the eye imaging apparatus may comprise a light source, an image sensor, a hand-held computing device, and an adaptation module. The adaptation module comprises a microcontroller and a signal processing unit configured to adapt the hand-held computing device to control the light source and the image sensor. In some embodiments, the imaging apparatus may comprise an exterior imaging module to image an anterior segment of the eye and/or a front imaging module to image a posterior segment of the eye. The eye imaging apparatus may be used in an eye imaging medical system. The images of the eye may be captured by the eye imaging apparatus, transferred to an image computing module, stored in an image storage module, and displayed in an image review module.
US10258307B2
An X-ray apparatus includes an X-ray radiator configured to radiate X-rays to an object and a controller configured to acquire orientation information indicating an orientation of the X-ray radiator and motion information indicating a movement of an X-ray detector configured to detect the X-rays radiated by the X-ray radiator and select the X-ray detector based on the orientation information and the motion information.
US10258303B2
The invention relates to an apparatus for determining a fractional flow reserve (FFR) value of the coronary artery system of a living being (3). A fractional flow reserve value determination unit (13) determines the FFR value by using an FFR value determination algorithm that is adapted to determine the FFR value based on a boundary condition and a provided representation of the coronary artery system, wherein the boundary condition is specific for the living being and determined by a boundary condition determination unit (12). Since the boundary condition determination unit determines a boundary condition, which is specific for the living being, and since the fractional flow reserve value determination unit not only uses the provided representation of the coronary artery system, but also the living being specific boundary condition for determining the FFR value, the accuracy of the FFR value, which is non-invasively determined, can be improved.
US10258294B2
The present invention provides an alarm controlling method, an alarm controlling apparatus and an adaptive alarming method for a patient monitor. The alarm controlling method comprises: acquiring false alarm probabilities of a plurality of current alarms; acquiring a corresponding alarm confidence according to a false alarm probability of each current alarm; and determining a priority of the current alarm based on at least the alarm confidence of the current alarm.
US10258288B2
Embodiments include a method and system for providing data to a user of a wearable sensor platform. The method may be performed by a least one software component executing on at least one processor. The method includes capturing data for the user using at least one sensor in the wearable sensor platform. The data includes physiological data and artifact data. The physiological data includes noise data therein. A confidence indicator for the data is determined based on at least one of the physiological data and the artifact data. A physiological data signal corresponding to the physiological data and the confidence indicator is provided to the user on the wearable device platform.
US10258262B2
The invention addresses confounding difficulties involving continuous sweat analyte measurement. Specifically, the present invention provides: at least one component capable of monitoring whether a sweat sensing device is in sufficient contact with a wearer's skin to allow proper device operation; at least one component capable of monitoring whether the device is operating on a wearer's skin; at least one means of determining whether the device wearer is a target individual within a probability range; at least one component capable of generating and communicating alert messages to the device user(s) related to: wearer safety, wearer physiological condition, compliance with a requirement to wear a device, device operation; compliance with a behavior requirement, or other purposes that may be derived from sweat sensor data; and the ability to utilize aggregated sweat sensor data that may be correlated with information external to the device to enhance the predictive capabilities of the device.
US10258254B2
An MRI prep scan acquires plural sets of echo signals at a plurality of cardiac time phases which are mutually different from each other for each slice and used to generate a plurality of respectively corresponding prep images. Reference information is acquired and displayed for determining a first cardiac time phase and a second cardiac time phase on the basis of the prep images. The first and second cardiac time phases are set in response to an operator's specification. An imaging scan section for acquiring imaging echo signals by performing an imaging scan is performed upon each of the first and second cardiac time phases to acquire imaging echo signals. A first image is generated based on an echo signal of the first cardiac time phase and a second image is generated based on an echo signal of the second cardiac time phase. A differential image is acquired by calculating a difference between the first image and the second image.
US10258241B2
In an embodiment, an apparatus for opto-acoustic imaging includes a first contact area adapted to apply a first pressure to a surface of an imaging volume of a subject and a second contact area adapted to apply a second pressure to the surface. The second contact area is configured to provide decreased blood exit from the imaging volume by restricting flow relative to the first contact area. An optical energy output port is provided to illuminate the imaging volume to produce opto-acoustic signals from an absorbed optical energy of blood in the imaging volume. The opto-acoustic signals are detected by one or more ultrasound transducers and processed by a processor to generate images of the volume. An image generated by processing the detected opto-acoustic signals is output on a display.
US10258238B2
Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at a plurality of temporal delays. A cross-correlation function of at least one of amplitude, phase and intensity of a scattered optical field is derived for a plurality of depths relative to the specified surface. A mean cross-correlation function is then derived for each depth and fit to obtain a diffusion coefficient, from which a relative viscosity characterizing the fluid is derived.
US10258236B2
A spectrometer includes an illuminating section; a receiving section configured to detect radiation reflected from an object including an optically inhomogeneous scattering medium; a hardware section configured to obtain a solution of an inverse problem to reconstruct an absorption spectrum of the optically inhomogeneous scattering medium, wherein the illuminating section includes at least one light-emitting diode source, a radiation spectral curve of which is divided, by at least two spectral filters having different spectral transmission curves, into at least two spectral regions, to form an equivalent radiation spectrum from at least two spectral sources, and wherein the hardware section applies the solution of the inverse problem based on information about a spectral content of the radiation of the illuminating section, a signal obtained in a form of a response from the optically inhomogeneous scattering medium, and a spectral sensitivity curve of the receiving section.
US10258228B2
A system for mounting a retractor tube to a spine without a guidewire is disclosed. The system includes an awl, a first dilator configured to be advanced over the awl, a retractor tube configured to be advanced over the first dilator, wherein an outer surface of the retractor tube defines a plurality of channels, and a plurality of pins adapted to be received within the plurality of channels, wherein the plurality of pins secure the retractor tube to the at least one vertebral body of the spine. A method for selectively mounting a retractor tube to a spine without a guidewire is also disclosed.
US10258227B1
Bilateral illumination attachment for dental camera is a light source that is reversibly attachable to any dental camera. Bilateral illumination attachment for dental camera has two light sources that directly face each other. When properly attached to a dental camera, bilateral illumination attachment for dental camera effectuates sub-enamel illumination or bilateral illumination of a tooth, so that the dental camera may capture a photo or image of the illuminated tooth. Bilateral illumination attachment for dental camera has a specially shaped rigid body that makes a slip-fit, press-fit, or snap-fit with the exterior surface of any dental camera. The distal end of specially shaped rigid body is sterilizeable. Bilateral illumination attachment for dental camera has a plurality of replaceable tooth cups where each tooth cup contains the two light sources. Replaceable tooth cups are placed on the tooth to effectuate sub-enamel illumination or bilateral illumination. Replaceable tooth cups are sterilizeable.
US10258224B2
An actuating member for making a flexible elongate member for medical use perform a predetermined action includes a push/pull member, an operating member, and an advancing member. The push/pull member includes a first moving portion and a second moving portion, which are movable relative to each other. The push/pull member is pushed/pulled in conjunction with a movement of the first moving portion and the second moving portion. The operating member effects the movement of the first moving portion and the second moving portion. The advancing member includes a narrowed portion that moves the first moving portion and the second moving portion in conjunction with an operation of the operating member. The push/pull member makes the elongate member perform at least one of (i) an advance/retraction action and (ii) a bending action by transmitting the movement of the first moving portion and the second moving portion to the elongate member.
US10258223B2
An inserting instrument includes a first flexible tube section having a flexibility lower than a spiral tube, a second flexible tube section having a flexibility lower than the spiral tube and equal to or higher than the first flexible tube section in a state where the second flexible tube section is not covered with the spiral tube. The flexibility of the second flexible tube section is lower than that of the first flexible tube section when the second flexible tube section is covered with the spiral tube. The inserting instrument includes a third flexible tube section provided on the proximal direction side with respect to the second flexible tube section and having a flexibility lower than the first flexible tube section.
US10258211B2
A floor tool for a cleaning appliance including a cleaner head rotatably attached to a conduit carried by a pair of wheels that converge beneath the conduit.
US10258208B2
A hand vacuum cleaner comprises a main body has a driving handle and houses a suction motor and fan assembly, the suction motor and fan assembly having a suction motor axis of rotation wherein the driving handle has a hand grip portion that extends upwardly and forwardly when the hand vacuum cleaner is oriented with the upper end above the lower end. An air treatment member has a dirt collection region having an openable door provided on a front end of the air treatment member.
US10258199B2
The present invention is a drink mixing device generally characterized as having a ball assembly in wireless communication with a base assembly. The base assembly comprises a casing for storing a first battery, a transmitter that receives power from the first battery, a base assembly wireless coil, a power port receiving for external power and host or peripheral connection, a button located along the casing wherein the button is electronically connected to the transmitter. The ball assembly comprises a casing for storing a second battery, a motor, a ball assembly wireless coil, and a receiver. The motor turns a propeller external to but affixed to the exterior of the ball assembly when the motor is powered and turned on. The propeller is protected by a metal spiral.
US10258198B2
A dual function garlic press includes an upper handle having a plunger, a lower handle having a receiving chamber and a cutter grid. The cutter grid is pivotally connected to the first side of plunger. The upper handle is rotatable in relation to the lower handle about a vertical axis between a first position where the first side of the plunger faces towards the receiving chamber when the upper handle and the lower handle are at the close position, and a second position where the second side of the plunger is juxtaposed to the bottom of the receiving chamber when the upper handle and the lower handle are at the close position to crush the item in the receiving chamber.
US10258195B2
A barbeque grill and oven or food smoker having an offset firebox configuration is disclosed. Example embodiments include: an oven having an enclosed interior region for cooking food items; an offset firebox sharing at least a portion of a side of the oven, the offset firebox having a first opening over which a removable grill may be placed, the firebox having a second opening through which airflow may travel from the firebox into the oven; an oven lid configured to produce an opening in the top of the oven of any desired size, the opening of the oven lid causing an increase in the flow of heated air from the firebox into the oven; and a controller coupled to a temperature sensor and an airflow conduit, the temperature sensor being terminated at a location in the oven to sense a temperature in the oven, the conduit being terminated at the offset firebox to deliver an airflow to stoke a fire in the offset firebox, the controller being configured to automatically generate an airflow in the conduit to drive the temperature in the oven to a desired temperature.
US10258193B1
A heat shield in the shape of a semi-sphere made of flexible material and having a centralized opening therein so that the heat shield can be slidingly placed on the shaft or handle of a cooking utensil. The outer shell of the heat shield also has a plurality of criss-crossed ribs disposed thereon wherein the ribs are strengthening ribs for providing additional rigidity to the flexible shell which is expected to be made of a flexible, stretchable material like silicone or the like. The central opening in the shell is designed to have a plurality of slits radially extending therefrom so that the opening is useful for mounting on utensils having a variety of diameters because the opening is variable in diameter due to the slits and stretchability and flexibility of the material.
US10258192B1
A cooking utensil is disclosed herein, in one example comprising: a cooking pan having a base panel with a perimeter sidewall extending thereabove around the circumference thereof so as to contain a volume of fluid in the cooking pan; a steamer insert pan is removably fitted within the cooking pan above the base panel. The steamer insert plate optionally having a surface defining a central void there through with a steamer dome attached to the steamer insert pan overlying the central void and extending vertically upwards therefrom. The steamer dome configure to extend into a food item to be cooked with a substantially non-permeable top cap so as to direct vapors from fluids heated within the cooking pan through the central void of the steamer insert plate and laterally through the side wall into the food item to be cooked.
US10258191B2
Various beverage preparation systems and methods are disclosed. The beverage preparation system can include a dispensing unit configured to receive beverage, such as a shot of espresso, from a beverage preparation machine. The dispensing unit can include a dispensing unit with a first end and a second end. The dispensing unit can be rotatable between an upright position and an inverted position. The dispensing unit can be configured to receive the beverage through the second end when the dispensing unit is in the upright position, and can be configured to receive cleansing fluid through the second end when the dispensing unit is in the inverted position. In some embodiments, when the dispensing unit is in an intermediate position between the upright and inverted positions, the dispensing unit is configured to dispense the beverage out of the first end and into a cup or other vessel.
US10258185B2
A system produces a brew from an infusible brew substance using a combination of a mug and a brewer housed within the mug. The mug includes a vessel inside the mug that holds the water used to brew the brew. The vessel has an exit port below its upper rim. A removable stopper closes the vessel. A siphon tube fits through the exit port and extends downward within the vessel to the siphon's suction end. A heating element is immersed in water within the vessel. When electrically energized, the heating element vaporizes the water, which rises to the top and pushes the water downward into the suction end. A mesh filter holds the infusible brew substance or the substance is placed in the bottom of the mug. The mesh filter is located below the siphon sticking out of the exit port. Water flows through the filter into the mug outside the vessel.
US10258182B2
A decorative tree ornament that is positioned atop a tree and that lights up and plays music while presenting an ornamental display that is attached to a rotating platform. The rotating is driven by a motor and support by a sheath that is designed to be fitted about the top of the tree. A plurality of slits traverses through the sheath, allowing the sheath to be navigated around the branches of the tree. A microcontroller dictates the speed of the motor, audio files played from a speaker, and the brightness and color of light emitted from a light assembly of the ornamental display. The light assembly is integrated into a festive diorama that is encased in a dome enclosure; the festive diorama and the dome enclosure both being removably attached to the rotating platform. A stabilization post is further utilized to support the sheath and the rotating platform.
US10258178B2
A pair of chopsticks in which each chopstick provides an extenuate body tapering to a tip with an internal weighting moving the center of gravity of the chopstick toward the tip with respect to the midpoint of the chopstick to provide improved operability and to permit the chopstick to rest on small dishes with the tip in a downward orientation when an edge of the dish supports the chopstick toward its tip with respect to the midpoint.
US10258175B2
A duvet cover is comprised of a base sheet and a top sheet interconnected together by a peripheral stitched seam. A down feather sheet is retained between the base sheet and the top sheet. The down feather sheet has a substantially constant density of down feathers with the down feathers being retained captive by a binder thereby the duvet cover has a substantially constant insulating factor throughout because the down feathers are immovably retained therein. Such a duvet cover permits the creation of all sorts of stitched or quilted designs therein without concern for the propagation of the down feathers between the base sheet and the top sheet of the duvet which would create irregular insulation.
US10258169B2
A merchandising system that improves the merchandising of product by limiting the number and the frequency with which product can be removed from, for example, a merchandising shelf. The merchandising system may include a base configured to support product and a housing configured to engage the base. The housing may comprise a top wall, a first side wall, a second side wall, and a front retaining wall mounted to the base at an angle. The system may further include a spring-urged pusher movably mounted on the base. The system may further include an opening defined by the first side wall and the front retaining wall through which product may be removed.
US10258167B2
An upper body garment for supporting an infant adjacent the chest and upper belly of a wearer that includes a tubular garment body made from a stretchable fabric and comprising a front panel and a back panel, one or more breast panels extending from a top portion of the back panel and over the shoulders of the wearer; and a pouch panel extending from a lower portion of the breast panels. The pouch panel is secured along a U-shaped seam to an inside surface of the front panel to form a pouch with a top opening proximate the lower portion of the breast panels. The stretchable fabric is a two-way stretchable fabric with an increased capability for elastic expansion within a substantially horizontal plane when the wearer is in an upright position.
US10258164B2
A mattress core with replaceable inner blocks includes a base, an open slot A located in the upper portion of the base, an open slot B located in the lower portion of the base, an inner block located within slot B and shaped to partially fill up slot B with the remaining space forming a groove in slot B, a strip-shaped inner block made of soft material and fit into the groove, and a cover plate configured to fit in said slot A.
US10258155B2
A movement control device is applicable to a first object and a second object movable relative to the first object. One of the first object and the second object is arranged with a first blocking part and a second blocking part, and the other one of the first object and the second object is movably arranged with a blocking member. When the second object is moved relative to the first object and the blocking member is moved from an initial position to a blocking position, the blocking member is configured to block one of the first blocking part and the second blocking part, in order to prevent the second object from being moved relative to the first object.
US10258154B2
An adjustable organizational system for single and multi-tiered cabinets, shelves, and drawers. The system segregates items inside a cabinet on different tiers of shelves, and then groups the segregated items on each shelf into size-dependent groups through length adjustable straps that have adjustable heights and lengths. Multiple groups of items can be segregated on the same shelf through positional and height adjustment of the straps. Straps are defined by a pair of free ends that are secured to the walls of cabinet to enable grouping of items based on the size, shape, and function of the item. Strap adjustment members detachably fasten free ends of straps into cabinet walls. Strap adjustment members comprise a side mounting block, a stud, and a retaining nut. Nut extends and retracts relative to stud and cabinet walls to adjust length and position of straps relative to adjacent straps and cabinet walls.
US10258152B1
A pivot block for a foldable shelving unit is disclosed. The pivot block includes a body having a first end, a second end, a top edge, a bottom edge, and a cutout portion positioned between the top edge and the bottom edge. The pivot block further includes a first securing portion located at the first end, the first securing portion configured to be secured to a spring, and a second securing portion located at the second end, the second securing portion configured to be secured to a portion of the foldable shelving unit. The pivot block also includes a pivot point located within the cutout portion. The pivot block is configured to assist a shelf of the foldable shelving unit to pivot at the pivot point between a first position and a second position.
US10258148B1
A convertible sit-to-stand desk has a desktop that is manually movable into and between a lowered position and a raised position, a base that is configured to support the desktop with respect to a supporting surface, and a supporting frame that supports the desktop with respect to the base. The supporting frame facilitates movement of the desktop into and between the lowered and raised positions. The supporting frame comprises first and second sub-frame assemblies disposed on opposite sides of the desktop, respectively.
US10258145B2
A shelf attachment assembly for attaching a shelf to a wall includes a removable shelf having a wall member and a hinge member at an angle to the wall member. The wall member includes a first aperture and a second aperture, the second aperture having a wall member portion as well as a hinge member portion. The shelf attachment assembly also includes a shelf attachment bracket which is fastenable to the wall. The shelf attachment bracket includes a first attachment and a second attachment aligned to receive the first aperture and second aperture, respectfully. The removable shelf is attached to the shelf attachment bracket, firstly, by inserting the second attachment through the hinge member portion of the second aperture. The removable shelf is then rotated such that the second attachment passes into the wall member portion of the second aperture and the first attachment is inserted through the first aperture.
US10258139B2
A tool for mechanical processing, preferably a brush, comprises a tool body, a plurality of filaments having a first portion anchored to the tool body and a second portion designed to apply a brushing action when the body is rotated about its axis, wherein the body comprises a retaining portion defining the body and made from a binder material in which the first portion of the filaments is embedded and incorporated to make it integral with the body. The body has a plurality of windows designed to improve the heat exchange of the first portion of the filaments with the environment during the rotation of the brush at high speeds so as to reduce the temperature.
US10258137B2
Various embodiments of a clip-on pouch to be attached to an article of clothing providing storage and immediate access to small items such as credit cards or spare keys for a home, car, or locker. The clip-on pouch is designed to be comfortable and concealable even when worn on undergarments. One embodiment provides storage for at least one spare key. Another embodiment provides a pouch sized large enough to store at least one credit card and spare key. Various designs for the clip are presented.
US10258136B2
A swivel-lock quick release is described. Embodiments of the swivel-lock quick release can include, but is not limited to, a male member adapted to mate with a female member wherein the male member can be disengaged by lifting and then rotating the male member while continuously lifting the male member. The male member can include a slot adapted to interface with a protrusion from the female member. The male member and the female member can each include an attachment mechanism to couple to various objects and/or tools.
US10258116B2
In a clasp (1), a male member (2) has a columnar insertion portion (23) and a female member (4) has a cylindrical housing portion (43). The clasp (1) has magnets which attract the insertion portion (23) into the housing portion (43). A male engagement body (3) is provided on an outer peripheral surface (23a) of the insertion portion (23) of the male member (2) while a female engagement body (5) is provided on an inner peripheral surface (43a) of the housing portion (43) of the female member (4). The male engagement body (3) and/or the female engagement body (5) is provided as a long protruding edge structure or a long recessed notch structure along the axis of the clasp (1), has a guiding portion (53), and also has a retaining portion (52) which prevents the insertion portion (23) from getting out of the housing portion (43).
US10258114B2
Stringers without fastener tape have continuous fastener elements and have element fixing members wherein the fastener elements are sewn together by a sewing thread. The element fixing members are inserted between upper and lower leg sections of the fastener elements. The sewing thread comes in contact with and straddles the upper and lower leg sections of each fastener element and pierces the element fixing members between the fastener elements. As a result of such stringers without fastener tape, the fastener elements can be held and the weight and cost of an article with a slide fastener can be reduced.
US10258106B2
The present invention relates to a skin film for uppers of shoes, which includes a polyurethane skin or a thermoplastic polyurethane film having a colored layer and a thermoplastic polyurethane hot melt film. The skin film is manufactured when an ethylene vinyl alcohol copolymer is formed between the TPU film and the hot melt film. The skin film can prevent dyes of a fabric material from being transferred to the skin film when the skin film is bonded to the fabric material, thereby preventing pollution of the colored layer of the skin film.
US10258100B1
A football helmet has a rigid plastic football helmet shell with a single raised plateau in the crown portion of the shell extending from the front portion, over the crown portion, toward the back portion. The raised plateau has a left border and a right border. The left border is composed of a plurality of segments and extends continuously from the front portion, over the crown portion, toward the back portion. The segments of the left border including at least a first segment and second segment, which meet to form an angle. A non-circular first ventilation hole through the shell has at least a first side, a second side, and a third side, and is positioned at the angle, such that the first side is adjacent to the first segment and the second side is adjacent to the second segment. The first segment extends beyond the first ventilation hole by a first distance at least as long as the first side and the second segment extending beyond the first ventilation hole by a second distance at least as long as the second side.
US10258094B2
A glove has a palm side and a back side joined at a side edge to form a glove body. The palm side and the back side are constructed from a stretch material. Panels attach to the stretch material on the palm side to form finger parts, palm parts and a back part. The panels are separated from each other by the stretch material to allow relative movement. Elastic bands attached to the panels on the back side adjust the fit. A thumb part has a gusset of the stretch material. Grip surfaces have an embossed texture with indentations.
US10258081B1
A device and system for packaging, storing, and smoking an organic smoking material, and a method of using same. In one embodiment, the system includes a container that includes a housing defining a chamber, a first compartment within the chamber, the first compartment having a first depth, a second compartment within the chamber adjacent the first compartment, the second compartment having a second depth that is less than the first depth, and a lid configured to provide an airtight seal to at least the second compartment. In one embodiment, the system further includes a smoking device having a bowl portion with a sharpened free edge that can be used to simultaneously cut organic smoking material within the second compartment and load the cut organic smoking material into the bowl portion. The system may also include a loading funnel and a pushing device for inserting organic smoking material into the container.
US10258078B2
A process for reducing the permeability of a paper wrapper used in the construction of a smoking article is disclosed. The paper wrapper is treated with a film-forming composition that forms treated discrete areas on the wrapper. The treated discrete areas have a permeability within a predetermined range sufficient to reduce the ignition proclivity properties of a smoking article made with the wrapper. In accordance with the present invention, the film-forming composition is applied as multiple layers to the paper wrapper. After each application step, the wrapper is dried. Applying the film-forming composition to the paper wrapper in multiple layers minimizes distortion and other adverse affects that may occur to the wrapper.
US10258076B2
A fiber-wrapped smokeless tobacco product includes smokeless tobacco and a plurality of polymeric fibers surrounding the smokeless tobacco. The polymeric fibers can have a basis weight of 5 gsm or less and a diameter of less than 100 microns. In some cases, the polymeric fibers are melt-blown polymeric fibers. In some cases, the polymeric fibers are centrifugal force spun polymeric fibers. A method of preparing a fiber-wrapped smokeless tobacco product includes melt-blowing or centrifugal force spinning a plurality of polymeric fibers to create an polymer deposition zone and passing a body comprising smokeless tobacco through the polymer deposition zone. In some cases, an electrostatic charge can be applied to the plurality of polymeric fibers, the body, or a combination thereof. In some cases, a spin is applied to the body when passing through the polymer deposition zone.
US10258075B2
A charcoal article for use of a hookah tobacco pipe is provided. The article comprises a body extending between a top and bottom portions. Plurality of legs extends outwardly from a base surface disposed between the top and bottom portions. The legs are separated from each other by channels, and a recess is provided extending inwardly within the body from the base surface. An inner chamber is defined within the body by the walls of the legs and walls of the recess. The legs are configured for placement on a foil, having at least one perforation, covering a bowl with a smoking matter. Upon positioning of the article on the foil the heating chamber is positioned to coincide with or situated at the perforation within the foil.
US10258074B2
Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
US10258070B1
A method for infusing a nut snack by immersing it in an aqueous flavoring solution and baking/roasting the moistened product to the desired texture, crunch, and appearance. The process not only enhances the flavor of the nut, it also produces a nut with no exterior residue. The method includes such steps as providing a portion of blanched nuts; adding the blanched nuts to water and a flavoring component in order to infuse the flavoring into the nuts; cooking the flavored nuts for a predetermined period of time to enhance the infusion process; rinsing the cooked nuts; and roasting the nuts.
US10258059B2
Disclosed is a novel instant coffee comprising aromatized soluble particles and a method of aromatizing soluble coffee particles. The soluble coffee particles are mixed with roast whole beans, and the mixture is held for at least two days. The result is aromatized soluble coffee particles, as evidenced by the presence of relatively high amounts of 2-methylpyrazine in instant coffee comprising said particles. The instant coffee has a favorable content in aroma components, yet with a low oil content.
US10258058B2
A method for preparing functional edible oil rich in phytosterol esters and diglycerides includes steps of: 1) adding a raw material: adding phytosterol, triglyceride and a molecular sieve into a reactor, wherein a ratio of the phytosterol and the triglyceride is 1:2-1:4, a molecular sieve amount is 50 g/L; heating to 50-60° C. and stirring for 30-60 min, for obtaining a pre-mixture; 2) providing non-aqueous enzymatic transesterification: adding 5-20 g/L lipase into the pre-mixture, adding 100-200 ppm antioxidant, stirring and reacting for 8-12 h with a temperature of 50-60° C. and an atmospheric pressure, stopping heating and naturally cooling to a room temperature; and 3) post-treating: after reaction, removing the lipase and the molecular sieve by centrifugation, for obtaining the functional edible oil. The functional edible oil rich in two nutritional active components is obtained by the one-step method. Products of the present invention do not need separation and purification, and operation is simple.
US10258056B2
A filtration system is arranged to safely vent a storage room into which a fog mixture is introduced. Venting the storage room reduces and/or prevents a substantial increase in the internal pressure of the storage room. To control the pressure differential between the storage room and the ambient air pressure, a venting manifold with an in-line duct fan is used, for example, to exhaust storage room air into the atmosphere. The exhausted storage room air is filtered to reduce the exfiltration of chemicals and/or other contaminants from the environmentally sealed storage room.
US10258053B2
Evisceration apparatus for eviscerating a poultry carcass suspended by the legs. The apparatus may include an evisceration tool that is movable up and down and into and out of a body cavity of the poultry. The evisceration tool can include two bracket halves that connect to each other with a hinge at a lower extremity of the tool, wherein the two bracket halves may be embodied with cooperating clamping faces adjacent to said hinge for clamping a part of the viscera of the poultry when the two bracket halves are moved towards each other from an open position into a closed position.
US10258050B2
A household mixer appliance having an open top mixing container, a hook and a drive arrangement. The mixing container has a side wall portion with a through hole for the drive arrangement and the hook is arranged to be rotatable around an axis of rotation within the mixing container via the drive arrangement. A seal is arranged between the drive arrangement and the side wall portion of the mixing container, and the drive arrangement includes a quick-release mechanism to which the hook is attachable.
US10258039B2
Provided is a compound capable of effectively control worst weeds of higher leaf stages that present practical problems. A specific pyrazolylpyrazole derivative of formula (I) is disclosed that is able to solve the above-mentioned problems.
US10258038B2
The present invention relates generally to the use of heterocyclic compounds of the formula (I) for controlling nematodes and to methods useful for controlling nematodes and/or increasing crop yield.
US10258035B2
A composition and method are used to treat articles suspected of contamination with bacterial spores. The composition and method are effective against bacterial spores selected from C. diff., C. botulinum, C. sporogenes, B. cereus, and B. subtilis. The article can be a textile or a hard surface. The method includes preparing a first use solution by mixing ether amine in water and a second use solution by mixing percarboxylic acid in water; applying the first use solution to the article; and applying the second use solution to the article. An alternative method includes preparing a mixture of ether amine, percarboxylic acid, and water, and applying the mixture to the article.
US10258034B2
Methods for reducing dust by treating a seed with a lubricant composition are described herein. The disclosure also provides for a method of reducing planter dust released during seed planting by applying a lubricant composition to a seed. Methods for increasing seed lubricity by coating a seed with a lubricant composition are also described. Compositions and seeds useful in these methods are also described.
US10258028B2
A sprayer boom for use with an agricultural sprayer has perforated outer walls. The perforated outer walls may connect boom frame tube stringers to each other by way of stringer connecting plates with cutouts. The perforated outer walls may be defined by webs of material extending between the tube stringers and multiple openings defined between the webs of material.
US10258027B2
The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
US10258020B2
An animal restraining or tethering device for permitting movement of an animal along paths having their extent defined by a telescoping elevated rod adapted to be mounted between opposing passenger grab handles in a vehicle or between opposing mounting locations in a truck bed, is described. One end of a component rod member and one end of a tube member are fitted with adjustable end connectors for reversible attachment of the rod assembled therefrom to the passenger grab handles or the truck bed attachment locations. At least one sliding member adapted to slidably move along the rod is attached to a leash or chain which is in turn connected to an animal collar or harness. The sliding member can also be fixed at a chosen location along the rod, if desired. Various rings and loops may be fastened to the rod at chosen locations for holding items placed in the vehicle, and for preventing these items from being thrown about as a result of vehicle movement.
US10258013B1
A soybean cultivar designated 64442216 is disclosed. The invention relates to the seeds of soybean cultivar 64442216, to the plants of soybean cultivar 64442216, to the plant parts of soybean cultivar 64442216, and to methods for producing progeny of soybean cultivar 64442216. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 64442216. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 64442216, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 64442216 with another soybean cultivar.
US10258011B1
A novel soybean variety, designated 5PWAV53 is provided. Also provided are the seeds of soybean variety 5PWAV53, cells from soybean variety 5PWAV53, plants of soybean 5PWAV53, and plant parts of soybean variety 5PWAV53. Methods provided include producing a soybean plant by crossing soybean variety 5PWAV53 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety 5PWAV53, methods for producing other soybean varieties or plant parts derived from soybean variety 5PWAV53, and methods of characterizing soybean variety 5PWAV53. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety 5PWAV53 are further provided.
US10258009B2
A soybean cultivar designated S170034 is disclosed. The invention relates to the seeds of soybean cultivar S170034, to the plants of soybean cultivar S170034, to the plant parts of soybean cultivar S170034, and to methods for producing progeny of soybean cultivar S170034. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S170034. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S170034, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S170034 with another soybean cultivar.
US10258006B1
A novel maize variety designated PH42GF and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH42GF with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH42GF through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH42GF or a locus conversion of PH42GF with another maize variety.
US10258004B2
Novel lettuce, such as lettuce designated SSC3237 (a.k.a., ‘SUREFIRE’) is disclosed. In some embodiments, the invention relates to the seeds of lettuce SSC3237 (a.k.a., ‘SUREFIRE’), to the plants and plant parts of lettuce SSC3237 (a.k.a., ‘SUREFIRE’), and to methods for producing a lettuce plant by crossing the lettuce SSC3237 (a.k.a., ‘SUREFIRE’) with itself or another lettuce plant. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other lettuce plants derived from the lettuce SSC3237 (a.k.a., ‘SUREFIRE’.
US10258001B2
The present invention relates to the field of spinach breeding, in particular to a new dominant resistance gene, designated RPF11, which confers resistance against races 7 to 14 of Peronospora farinosa and to spinach plants comprising said gene.
US10258000B2
Inbred corn lines, designated BC143 is disclosed. The invention relates to the seeds of inbred corn lines BC143 to the plants and plant parts of inbred corn lines BC143 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn lines BC143 with itself or another corn line. The invention also relates to products produced from the seeds, plants, or parts thereof, of inbred corn line BC143 and/or of the hybrids produced using the inbred as a parent. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from inbred corn lines BC143.
US10257987B2
A feeding system for an agricultural implement includes a hopper configured to receive agricultural crop material. An auger extending across the hopper is configured to meter the agricultural crop material from the hopper into a tapered passageway. A movable belt is disposed along one side of the tapered passageway and is configured to urge the agricultural crop material through the tapered passageway toward an outlet of the tapered passageway to form the agricultural crop material into a mat having a thickness substantially equal to a width of the outlet.
US10257986B1
A continuous roll of wrapping material for crops such as baled cotton wherein wrapping segments are set off by spaced transverse lines of slits or scoring for predictable separation during the wrapping process. Protection of the transverse lines and sealing assistance may be included by the addition of an adhesive layer and a V-fold over the transverse lines.