US10584193B2
These flat elliptical polymer particles have a front view, a planar view, and a side view in a projection diagram based on third-angle projection which are all elliptical. The flat elliptical polymer particles satisfy (1)-(4): (1) the average length (LAV) of flat portions satisfies 0.13≤(LAV)≤500 μm; (2) the average breadth (DAV) of the flat portions satisfies 0.1≤(DAV)≤250 μm; (3) the average (P1AV) aspect ratio (L/D) calculated from the length (L) and the breadth (D) satisfies 1.3
US10584192B2
The present disclosure provides a solid catalyst component obtainable by a process including: (a) a first step in which Ti(OEt)4, is reacted with a Mg based compound of formula MgCln(ORI)2-n, where n is from about 0.5 to about 1.5, RI is a C1-C10 alkyl groups, the Ti(OEt)4 and the Mg compound are used in amounts such that the Ti/Mg molar ratio is of about 0.2 to about 0.4, the reaction temperature is about 110 to about 130° C., and the reaction time is about 2 to about 5 hours; and (b) a subsequent step in which the product obtained in step (a) is reacted with a Ti compound of the formula Ti(ORI)4-yCly, where y is a number between 3 and 4.
US10584189B2
A β-phase PVDF is prepared through a controllable dehydrofluorination under either a basic or high temperature condition. PVDF is degraded by losing hydrogen fluoride (HF) and either carbon-carbon double bonds form in the molecular backbone or single bonds form crosslinking the two polymer chains. These changes in structure influence the crystallization behavior of PVDF and therefore, influence the electrical properties by changing the arrangement of the dipoles.
US10584188B2
A photoinitiator of Formula I includes a benzophenone moiety, a nitrogen-containing moiety (NCM) covalently bonded to the benzophenone moiety, and an unsaturated polymerizable moiety (PM) covalently bonded to the nitrogen-containing moiety. The unsaturated polymerizable moiety includes an acrylate group or a methacrylate group.
US10584185B2
Systems and methods for extracting useful by-products and natural rubber from non-Hevea rubber bearing plants are disclosed.
US10584177B2
Described herein are anti-MCAM antibodies and antigen binding fragments thereof that are capable of inhibiting the interaction between MCAM and its ligand, a protein comprising a laminin α-4 chain. These anti-MCAM antibodies and antigen binding fragments thereof may be useful for, for example, treating inflammatory conditions characterized by the infiltration of MCAM-expressing cells into a site of inflammation in the body.
US10584176B2
The present invention relates to Fc variants having increased affinity for FcγRIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
US10584174B2
Bispecific antibody compounds, and methods of using same, are provided which bind and neutralize Dkk-1 and RANKL and which are useful as adjuncts to spinal fusion surgery or as agents for bone healing or treating conditions associated with bone loss or degeneration.
US10584170B2
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a therapeutically effective amount of an antibody that inhibits signaling from the PD-1/PD-L1 signaling pathway. This disclosure also provides a method for immunotherapy of a subject afflicted with cancer comprising selecting a subject that is a suitable candidate for immunotherapy based on an assessment that the proportion of cells in a test tissue sample from the subject that express PD-L1 on the cell surface exceeds a predetermined threshold level, and administering a therapeutically effective amount of an anti-PD-1 antibody to the selected subject. The invention additionally provides rabbit mAbs that bind specifically to a cell surface-expressed PD-L1 antigen in a FFPE tissue sample, and an automated IHC method for assessing cell surface expression in FFPE tissues using the provided anti-PD-L1 Abs.
US10584164B2
The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC) and C5a anaphylatoxin-mediated inflammation and, thus, treating complement-associated disorders. The antibodies have a number of improved properties relative to eculizumab, including, e.g., increased serum half-life in a human.
US10584161B2
Monoclonal antibodies that specifically bind the nucleocapsid protein of Heartland virus (HRTV) are described. The monoclonal antibodies can be used, for example, in immunoassays to detect HRTV-specific antibodies in a biological sample or to detect HRTV in a cell or tissue sample. The monoclonal antibodies can also be used to diagnose or treat an HRTV infection.
US10584151B2
The present invention relates to the field of biotechnology and genetic engineering, and particularly to the expression of recombinant peptides. The inoculation thereof in cattle results in the production of an immune response capable of adversely affecting Rhipicephalus microplus ticks, which feed on the inoculated cattle, decreasing the number and reproductive capacity of this tick species. Such recombinant immunogen can be used as an effective vaccine for tick control. The technical goal is the design and construction of two synthetic genes made with preferred codons for Pichia pastoris and expression thereof from a recombinant peptide, which consists in a continuous sequence and of a recombinant peptide, respectively, and the drug composition based of said recombinant polypeptide.
US10584144B2
The presently-disclosed subject matter relates to an artificial RNA nanostructure molecule and method to treat brain tumor in a subject. More particularly, the presently disclosed subject matter relates to a RNA nanostructure containing a multiple branched RNA nanoparticle, a brain tumor targeting module, and an effective amount of a therapeutic agent. Further, the presently disclosed subject matter relates to a method of using the RNA nanostructure composition to treat brain tumor in a subject having or at risk of having brain tumor.
US10584140B2
The present invention relates to a method for efficiently producing a ruthenium complex (1A) by reacting a dinuclear ruthenium complex (2A) with a compound (3A) in the presence of a primary alcohol and a base. The ruthenium complex (1A) can also be efficiently produced by treating a dinuclear ruthenium complex (4A) with a primary alcohol and a base. (In the formulas, solid lines, triple lines, broken lines, C, H, N, OP, Ru, X, AH and R1 to R12 have the meanings defined in the specification.)
US10584139B2
A multi-branched cationic phosphonium salt is provided. The multi-branched cationic phosphonium salt has a structure represented by formula (I): {Z[P+(R1)(R2)(R3)]n}(X−)n (I) wherein each of R1, R2, and R3 is independently a linear or branched C1˜C10 alkyl group, X− is an organic or inorganic anion, and Z has a structure represented by Formula (IIb) or Formula (IIc): wherein a is an integer of 1˜15. In Formulas (IIb) and (IIc), Z is connected to [P+(R1)(R2)(R3)] at the position marked by an asterisk (*), and n is an integer of 3˜4.
US10584134B2
The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
US10584133B2
The present disclosure provides compounds that modulate protein function and/or restore protein homeostasis. The disclosure provides methods of modulating protein-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other therapeutic agents, are provided.
US10584129B2
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.
US10584126B2
The present invention relates to compounds of formula(I), a process for their production and their use in electronic devices, especially electroluminescent devices. When used as charge transport material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency and reduced driving voltage of electroluminescent devices.
US10584120B1
Benzimidazole compounds of formula (I), shown below, are disclosed. The compounds are potent human glutaminyl cyclase inhibitors. Also disclosed is a pharmaceutical composition containing one of these compounds and a pharmaceutical acceptable carrier, as well as a method of treating Alzheimer's disease or Huntington's disease by administering to a subject in need thereof an effective amount of such a compound.
US10584119B2
The present invention comprises compounds of Formula I and their use in the inhibition of cell proliferation in therapeutic treatments. Pharmaceutical compositions comprising at least one compound of Formula I and at least one pharmaceutical excipient are disclosed, as well as methods of using compounds of Formula I and pharmaceutical compositions thereof for treatment of hyper-proliferative diseases and other disorders.
US10584118B2
The invention relates to 2,5-disubstituted benzoxazole and benzothiazole derivatives of Formula (I) wherein L, X, Y, and ring (A) are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds may be useful for the prevention or treatment of diseases or disorders associated with impaired reactive oxygen species (ROS) production, and/or for the prevention or treatment of various fibrotic diseases.
US10584115B2
Amine substituted pyridine and pyrazine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein.
US10584111B2
The disclosures herein relate to novel compounds of formula wherein R1, R2, R3 and R4 and n are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of inflammation, neurological or psychiatric disorders associated with modulating mGlu5 receptor function.
US10584109B2
The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
US10584104B2
The present invention relates to the pharmaceutical field for the treatment of hyperuricemia and gout. In particular, the present invention relates to a carboxylic acid urate transporter 1 (URAT1) inhibitor of a general formula (I) containing a diarylmethane structure and a preparation method thereof, and a pharmaceutical composition containing the same and a use thereof in the preparation of medicaments for treating hyperuricemia and gout, wherein R1 is selected from H, C1-C10 alkyl, C3-C10 cycloalkyl, F, Cl, Br, I, CN, NO2, SR4 or OR4; R2 is selected from H, F, Cl, Br or I; R3 is selected from H or C1-C4 alkyl; X is selected from S or CH2; wherein R4 is selected from C1-C10 alkyl.
US10584103B2
Provided herein are small molecule neurotensin receptor agonists, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
US10584102B2
Provided herein is a process for preparing a pyridazine amine compound of formula V, and a process for preparing dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof. Further, provided herein are novel dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof, wherein the amino group is an ethylamino group.
US10584097B2
The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.
US10584085B2
The present invention relates to a process for etherification of mixed olefinic light naphtha boiling in the range of C5-90° C. cut with simultaneous minimization of unreacted methanol concentration in the product. The etherification of mixed olefinic light naphtha produces the high octane blending component which can be blended directly in the gasoline pool without any recovery of the feed oxygenates like methanol, ethanol etc. which conventionally uses energy intensive separation processes.
US10584079B2
An alkylation process and apparatus are described. The alkylation process includes pre-mixing a paraffin stream with an ionic liquid catalyst stream from a settler. The premixed paraffin and ionic liquid catalyst stream is mixed in a low-efficiency pump to form a paraffin and ionic liquid catalyst mixture. An olefin feed stream is introduced into a riser reactor. The paraffin and ionic liquid catalyst mixture is introduced into the riser reactor to form a reaction mixture comprising alkylate and the ionic liquid catalyst. The reaction mixture is separated in a settler into an ionic liquid catalyst stream and a hydrocarbon stream.
US10584076B1
An in-situ process for synthesizing highly pyrophoric foam materials using metal and carbon precursors wherein the precursors serve as foaming and activating agents to disperse and lock nano-sized metal particles within a rigid porous carbon matrix. The resulting carbon matrix is also pyrophoric.
US10584074B2
The present invention relates to an improved nitrification inhibitor composition and its use in agricultural applications.
US10584073B2
Contemplated compositions and methods for treating in service concrete includes the step of contacting a portion of the in service concrete with an composition, wherein the composition comprises a base and at least one of an acid and a salt of an acid in an amount effective to convert insoluble calcium salts into soluble calcium gluconates that can be washed away with water or other liquid.
US10584068B2
An article comprises a plasma resistant ceramic material comprising 80-90 mol % of Y2O3, over 0 mol % to 20 mol % of ZrO2, and 10-20 mol % of Al2O3.
US10584067B2
Disclosed is a focused ultrasonic piezoelectric actuator having a novel type of piezoelectric device for focusing ultrasonic waves. The focused ultrasonic piezoelectric actuator includes a dome-shaped piezoelectric body for focusing ultrasonic waves and a rim configured to facilitate focusing of ultrasonic waves of the body and injection of the dome-shaped piezoelectric body during a powder injection molding process, remove warpage of the dome-shaped body during a sintering process, and reinforce focusing intensity of the ultrasonic waves. The rim is integrally formed with the body. Accordingly, in the focused ultrasonic piezoelectric actuator, a dome-shaped focused ultrasonic piezoelectric actuator for focusing ultrasonic waves using a thickness vibration mode at a MHz frequency band is easily manufactured by a powder injection molding method, and thus an ultrasonic focusing effect is maximized.
US10584063B2
The present invention provides a calcium sulphate-based product (e.g. a wall board) comprising gypsum, a pozzolan source such as a clay additive, rice husk ash or diatomaceous earth and a metal salt additive. The product may be produced by drying an aqueous slurry comprising calcined gypsum, the pozzolan source and the metal salt additive. The clay additive may be a kaolinitic clay. The metal salt additive may be a magnesium salt e.g. magnesium nitrate, magnesium chloride or magnesium hydroxide.
US10584047B2
Processes are disclosed for the microbial nitritation of ammonia that attenuate the production of at least one of nitrate anion and nitrous oxide. The processes use an ME biocatalyst having a highly porous, hydrophilic polymeric structure with ammonia-oxidizing microorganisms substantially irreversibly retained therein. The processes are particularly useful for integration with anammox processes.
US10584045B1
An apparatus and method for oxygenating a flow of mixed liquor, typically from an aeration tank, to a secondary clarifier permits further biological reduction of biochemical oxygen demand (BOD) of a waste stream, such as waste water while resident in the secondary clarifier. In some embodiments, the mixed liquor may be oxygenated to levels at or above about 4 mg/L. Depending upon the user requirements and the BOD of the waste stream, all or a portion of the mixed liquor may be treated to raise the dissolved oxygen content. Various apparatus may be used for superoxygenation, including, as one example, a superoxygenation cone, such as a Speece cone.
US10584043B2
A capacitive deionization apparatus may include at least one pair of porous electrodes and a spacer structure disposed between the at least one pair of electrodes. The at least one pair of porous electrodes may include an electrode material having a surface area for the electrostatic adsorption of feed ions. The spacer structure may include an electrically-insulating material with an ion exchange group on the surface thereof. The spacer structure provides a path for flowing a fluid therethrough.
US10584041B2
The present disclosure relates a system for the treatment of water. The water treatment system may be linked an aquatic protection system or a water filtration system.
US10584038B2
The present invention relates to a process for the preparation of precipitated calcium carbonate allowing for a more sustainable and cost-efficient use of milk of lime. The obtainable products show good optical properties as well as fine particle size distributions.
US10584037B2
Embodiments of the invention relate to systems, methods, and equipment to make lithium hydroxide from lithium salts.
US10584035B2
A system for purifying trichlorosilane that can prevent re-contamination by the dissociation of an adduct occurring in association with the conversion of high boiling point compounds or the remaining of impurities due to an equilibrium constraint is provided. Trichlorosilane containing impurities serving as a donor or an acceptor in silicon crystals is supplied to a multistage impurity conversion step. These impurities in the trichlorosilane are converted into high boiling point compounds in the presence of a distillation aid. A plurality of impurity conversion step sections (101 to 10n) are connected in series, and any of the impurity conversion step sections comprises a reception section a for the trichlorosilane from the preceding stage section, an introduction section b for the distillation aid, a transmission section c for the trichlorosilane to the subsequent stage section, and a drain section d that discharges a remainder out of the impurity conversion step section.
US10584033B2
A method for synthesizing carbon nanocages, including N-doped carbon nanocages, includes a first step of forming a solution including a metal salt and an organic carbon source; a second step of drying the solution to obtain a precursor powder; and a third step of annealing the precursor powder to obtain a nanocage including a metal nanoparticle surrounded by a carbon shell. The metal nanoparticle is then removed from the carbon shell by applying an acid solution.
US10584024B2
Various systems, devices, and methods are provided for facilitating communication between a forecourt controller and a fuel dispenser. In certain aspects, a fuel controller translator is provided for translating commands transmitted between the forecourt controller and the fuel dispenser. For example, where the forecourt controller transmits commands that are compatible with the payment terminal, but not with the fuel controller, the fuel controller translator can translate the commands received from the forecourt controller into a format compatible with the fuel controller. Conversely, the fuel controller translator can translate commands received from the fuel controller into a format that is compatible with the forecourt controller.
US10584012B2
The present invention relates to a cable spool arrangement for use in automated cable winding applications, said cable spool arrangement comprising a first core half and a second core half, each one of the first and second core halves comprising an outer wall having a conical section, wherein each one of said first core half and said second core half comprises a connecting arrangement configured to connect said first core half and said second core half together, and comprising at least one protrusion and at least one recess. The present invention also relates to a stackable cable spool half.
US10584007B2
A sheet feeding apparatus includes a stacking surface on which a sheet is stacked, a feed portion configured to feed the sheet in a sheet feeding direction, and first and second detecting portions disposed at positions different from each other in a width direction orthogonal to the sheet feeding direction and so as to overlap with the stacking surface in a view from a height direction orthogonal to the stacking surface. The first and second detecting portions detect height positions which are positions in the height direction of an uppermost sheet. In addition, a control portion stops feeding the sheet by the feed portion based on at least one a height position detected by the first detecting portion and a height position detected by the second portion in feeding the sheet.
US10584004B2
A sheet conveying apparatus, including: a sheet storage portion; a roller to convey sheets by rotating about a rotation axis; an arm rotatably supporting the roller and pivotable about an arm pivot axis; a presser plate pivotable about a presser-plate pivot axis; and a pivot mechanism to pivot the presser plate such that a contact angle, which is an angle defined upstream in a sheet conveyance direction by the arm and an uppermost one of the sheets contacting the roller, is less than a maximum angle in a time period from a sheet maximally loaded state to a sheet minimally loaded state, the maximum angle being an angle defined upstream in the conveyance direction by: only one sheet assumed to be placed on the presser plate which is the presser plate in the maximally loaded state; and the arm the roller of which contacts the one sheet.
US10583998B2
An automatic egg tray stacking apparatus turns alternate egg trays through the operation of movable guides at the junction with a loading conveyor before conveying the egg trays toward a stacking mechanism that first stops the egg tray and then lowers the stack on top of the egg tray before re-elevating the partially formed stack to permit the entrance of a new egg tray into the stacking mechanism. Once the stack of egg trays is completed, the stack is allowed to move onto a stack conveyor and is moved forwardly for shipment. The stacking mechanism is operated by a single actuator having dual pneumatic cylinders that provide a three position operation of the lifting function with the stacking mechanism having lifter members engaging all four sides of the lowermost egg tray of the elevated stack. A control mechanism operates the apparatus with input from appropriately positioned sensors.
US10583994B2
Provided is a conveyor belt monitoring system that determines whether or not an abnormality has occurred in the conveyor belt. The system successively detects elongation of a running conveyor belt using an elongation detection mechanism, and further successively detects tension acting on a core layer forming the conveyor belt on the basis of power consumption of the running conveyor belt. On the basis of data obtained, the system monitors the presence/absence of the abnormality in the conveyor belt using a control unit.
US10583987B2
A wear resistant funnel sheet element for a material guide chute includes first and second edges located at a tapered angle from each other. Interlinking fastening features are provided in order to mate the respective edges of at least one of the wear resistant funnel sheets to form a funnel element. The sheet element may be a molded flat piece of a rubber material, which serves as an interchangeable wear part on a material guide chute.
US10583985B2
An article storage facility includes a first rail extending along a rail extending direction, a first storage rack configured to store a plurality of articles, a first transport device configured to move along the first rail and to transfer an article to and from the first storage rack, a second rail extending along the rail extending direction; and a second storage rack configured to store a plurality of articles, and a second transport device configured to move along the second rail and to transfer an article to and from the second storage rack. The first rail and the second rail are spaced apart by a set distance from each other along the rail extending direction. A third rail extends along the rail extending direction between the first rail and the second rail, and has a length less than the set distance. The third rail includes a fixed base and a movable rail portion. The movable rail portion is so configured that a location of the movable rail portion with respect to the fixed base when fixed to the fixed base can be changed.
US10583981B2
A method for constructing a carton flow bed rack (1) includes specifying a number of levels of the carton flow bed rack (1). The method also includes specifying whether and where each level has a load end, and/or an unload end, and/or a stop end. The method further includes specifying at least one of a height, a width, and a depth of the carton flow bed rack and providing and dimensioning components for assembling the carton flow bed rack according to the specifications.
US10583974B2
A unitary package including a rolled tissue product and a packaged tissue product overwrapped with a packaging film. The packaged tissue product may be disposed in a folded over portion of a divider and co-packed with first and second rolled tissue products, which differ in at least one regard, to increase the stability of the package. The rolled tissue products preferably comprise a plurality of rolled towel products having a first height and a plurality of rolled bath tissue products having a second height, where the first height is greater than the second height. The divider, packaged tissue product and first and second rolled tissue products are generally packaged together to form a cubic package.
US10583960B2
A selectively height adjustable pallet including a first member having a first outer surface and a first inner surface, a second member having a second outer surface and a second inner surface, and a plurality of selectively adjustable supports arranged between the first member and the second member. The selectively adjustable supports being operable to establish a first distance between the first inner surface and the second inner surface in a first configuration and a second distance, distinct from the first distance between the first inner surface and the second inner surface in a second configuration. At least one cross member is selectively arranged between the first inner surface and the second inner surface when the plurality of adjustable supports are in one of the first configuration and the second configuration.
US10583954B2
A packaging for a shaver may include a shell configured to shift between a closed configuration and an open configuration, wherein the shell is configured to receive the shaver. The packaging may also include an image of the shaver disposed on an outer surface of the shell, and an actuator coupled to the outer surface of shell, the actuator being disposed within the image of the shaver, and wherein activation of the actuator while the shell is in the closed configuration, causes the shell to shift from the closed configuration to the open configuration.
US10583950B1
A device including: a finger guard implement, wherein the finger guard implement is configured to protect a finger from a needle injury of a tagging gun for attaching tags to a piece of clothing, apparel or garment; a central guard section, wherein the central guard section is configured to impenetrable by the needle; a central guard top portion, in which a silicone material is molded on the central guard top portion, wherein the silicone material is configured to allow the needle to pass through, thereby, attaching tags to clothing, apparel or garment; and a bar portion, wherein the bar portion is configured to secure the finger guard implement to the finger.
US10583943B2
Method and system for automatically processing blanks for forming packaging boxes. By means of a feeding conveyor blank material is fed in a feeding direction from a storage of blank material to a single blank cutting station comprising a blank forming apparatus for cutting and creasing blank material into a blank. By means of said blank forming apparatus a blank is formed having a rectangular bottom panel and rectangular corner, side and end panels. Cutting and creasing blank material into the blank is performed during feeding of said blank material in feeding direction through the blank forming apparatus.
US10583940B2
A compartment for a space vehicle includes a pressurized structure having a structural wall, the structural wall having interior surfaces facing an interior of the compartment and exterior surfaces exposed to an external environment. An internal mounting structure for mounting a component is provided within the compartment, and mounting features support the internal mounting structure from the pressurized structure. The internal mounting structure is spaced away from the interior surfaces of the pressurized structure, and a thermal fluid is provided in the pressurized structure. The thermal fluid enables convective heat transfer between the component mounted on the internal mounting structure and the interior surfaces of the pressurized structure.
US10583934B2
To provide a fuel pipe of an aircraft that makes it possible to maintain temperature of fuel in the fuel pipe at appropriate temperature while giving consideration to reliability that is constantly required for the aircraft. A fuel pipe provided in an airframe of the aircraft includes: an inner pipe defining a flow path through which fuel flows; and an outer pipe surrounding an outer periphery of the inner pipe. A gap is provided between the outer periphery of the inner pipe and an inner periphery of the outer pipe. The inner pipe is made of a rubber material, and the outer pipe is made of a metal material.
US10583929B2
A multicopter having a plurality of propellers is configured to be electrically operated. The multicopter is provided with electric motors, at least one main battery, a generator, an engine, and a battery condition detecting section. The electric motors drive the propellers. The main battery is a first electric power source that supplies the electric power to the electric motors. The generator is a second electric power source that supplies the electric power to the electric motors. The engine drives the generator. The battery condition detecting section detects abnormality of the main battery. When the battery condition detecting section detects the abnormality of the main battery, the generator supplies the electric power that has been converted from motive power from the engine directly to the electric motors.
US10583926B2
A seat attachable to a floor of a vehicle includes a seat frame movable between a first position and a second position and a mounting assembly attached to the seat frame and configured to be secured to the floor. The mounting assembly and seat frame are configured so that when the seat frame is in the second position first and second sliding assemblies of the mounting assembly are both located in forwardly extended positions and no part of the mounting assembly contacts the floor forward of a front connection of the mounting assembly.
US10583922B1
A configurable unmanned aerial vehicle (UAV) may include swappable avionics that may be selectable for use with other UAV components to build a customized UAV just prior to deployment of the UAV that is configured to deliver a package to a destination. Various factors may be involved in the selection of the avionics, such as an availability of different avionics, payload requirements (size, weight, etc.), environmental conditions along an anticipated route of flight, a region of use of the UAV, compatibility, a distance of the flight, power considerations, security considerations, and/or other factors. The avionics may include various hardware and/or software which may provide control output (e.g., data, power, and/or mechanical) to other components and/or systems, including a propulsion system. Coupling devices may selectively couple the avionics to other components of the UAV, such as to a battery, a cargo bay or package, and/or to a propulsion system.
US10583915B2
Systems and methods are provided for aircraft spoiler lockout. One embodiment is a system that includes a locking device that removably engages a control member inside a cockpit of an aircraft. The locking device restricts motion of the control member to prevent movement of wing surfaces of the aircraft. The system further includes a controller in communication with a wireless transmitter. The controller determines from a signal sent by the wireless transmitter whether both handheld switches connected to the wireless transmitter are being actively held. If so, the controller directs a supply of power to the locking device thereby causing the locking device to temporarily release the control member. Otherwise, the locking device restricts motion of the control member.
US10583909B2
A method of manufacturing a foldable aerodynamic structure, such as a wing, for an aircraft. The wing (1) including an inner region (1) and an outer region (3) rotatable relative to the inner region between a flight configuration and a ground configuration. The method includes designing the foldable aerodynamic structure by determining the location and orientation of an Euler axis of rotation (11) about which the outer region rotates to achieve the ground configuration and determining a cut plane (13), perpendicular to that Euler axis, separating the inner and outer regions; and iteratively repeating this process until a preferred cut plane (13) is obtained that satisfies at least one design criteria.
US10583907B2
A small marine vessel includes a vessel body, a propulsion device, a propulsion device housing provided in a rear portion of the vessel body and that houses the propulsion device, a first cover that substantially covers and seals the propulsion device housing, and a second cover disposed above the first cover and that covers the first cover and an opening of the propulsion device housing.
US10583904B2
An apparatus is disclosed having a sensor configured to measure a biological parameter of a diver and transmit a sensor signal. A controller is configured to determine that the biological parameter value correlated to the sensor signal is anomalous and responsively issue a rescue deployment signal to a buoyancy valve assembly. The buoyancy valve assembly has an inlet port connectable to a source of pressurized gas and an outlet port connectable to a buoyancy control bladder. The buoyancy valve assembly configured to receive the rescue deployment signal and responsively supply pressurized gas from the inlet port to the outlet port and buoyancy bladder, whereby the diver may ascend the water surface, even if disabled.
US10583899B2
A lighthouse lantern comprising a power supply and a phosphor-containing emitter is disclosed. The lighthouse lantern includes a power supply; a laser diode configured for receiving power from the power supply and irradiating laser in one direction; a phosphor-containing emitter positioned on a traveling line of the laser, wherein the emitter is configured for receiving the laser and emitting light; and a pair of reflective structures disposed symmetrically with respect to the phosphor-containing emitter, wherein each reflective structure has a reflective surface inclined in a direction away from the phosphor-containing emitter, wherein the reflective surfaces of the reflective structures are symmetrical with each other with respect to the phosphor-containing emitter. In accordance with the present disclosure, the lighthouse lantern may generate high output with low input power and thus has improved power efficiency, may suppress frequent failures near sea or seawater, and may reduce production costs.
US10583893B2
An electric bicycle having an electric motor mounted to a frame of the bicycle and which includes a motor output shaft defining an output end engaging a drive chain of the bicycles drive train to transmit the drive of the electric motor thereto. A torque sensor includes a base mounted in fixed relation to the frame and/or the electric motor. The torque sensor has a flexible arm extending from the base and a sensing member mounted to an extremity of the flexible arm that is displaceable relative to the base. The sensing member engages the drive chain along a segment thereof and is displaceable thereby. The segment of the drive chain extends from the output end of the motor output shaft to the pedal crank of the drive train.
US10583891B2
A clipless pedal system is provided. In various embodiments, systems of the present disclosure comprise pedals and cleats for interaction with the pedals. At least one of a pedal and an associated cleat comprises a magnet, and at least one of the pedal and the associated cleat comprises a ferrous metal for interaction with the magnet. Geometric features are provided to enable both a secure connection between a cleat and a pedal and to enable a user-friendly release of the cleat from the pedal.
US10583885B2
A motor vehicle forecarriage comprises a forecarriage frame, a pair of front wheels kinematically connected to the forecarriage frame by means of an articulated quadrilateral, said articulated quadrilateral comprising a pair of cross members, hinged to the forecarriage frame in correspondence of middle hinges, said cross members being connected together, in correspondence of opposite transverse ends by means of uprights pivoted to said transverse ends in correspondence of side hinges, wherein the cross members and the uprights define said articulated quadrilateral. Advantageously, each of the uprights guides and supports a stub axle of a front wheel, each upright extending from an upper end to a lower end, wherein each stub axle is mechanically connected to a rotation pin of a front wheel so as to rotatably support the wheel around a relative rotation axis.
US10583883B2
The present document describes a system for hooking and unhooking a bag with respect to a fixed structure of a motorcycle that comprises a tubular fixing frame, configured to be constrained to the fixed structure, one or more fixing blocks, configured to be constrained on predefined portions of the bag and to engage with the tubular fixing frame, and a fixing group, configured to be constrained to the bag and provided with one or more hook-shaped movable hooking means. The movable hooking means are rotatably actuatable, by means of a lock mechanism, between a first operative configuration, in which the movable hooking means are engaged with the tubular fixing frame, and a second non-operative configuration, in which the movable hooking means are released with respect to the tubular fixing frame and it is possible to obtain the unhooking of the bag from the motorcycle. The system also comprises a lock element integrally mounted on the fixing group and configured to maintain the movable hooking means locked when the lock mechanism is not actuated. The fixing group comprises first elastic means, configured to move the movable hooking means between the first operative configuration and the second non-operative configuration, and second elastic means, configured to move the movable hooking means between the second non-operative configuration and the first operative configuration.
US10583877B2
A torque stick apparatus for driving a personal transporter across a transport surface by positioning the torque stick apparatus against a drive surface is described. The torque stick apparatus includes a tubular housing, throttle control, battery pack, motor coupled to a wheel, and motor controller. The motor controller is coupled to the motor, the battery pack, and the throttle control. The motor controller determines whether to select regenerative braking mode based at least in part on the position of the throttle control. The motor controller supplies power from the battery pack to the motor in accordance with the throttle control when regenerative braking mode is not selected. The motor controller provides power from the motor to the battery pack when regenerative braking is selected. The battery pack and the motor controller are contained within the housing.
US10583876B2
A device for fixing an air guiding means to a motor vehicle includes an articulator including a plurality of joints configured to be pivoted relative to one another, a first of the plurality of joints configured to be connected to the air guiding means, wherein the first joint is translationally displaceable relative to a second of the plurality of joints.
US10583871B2
A method of constructing a vehicle component includes depositing a layer of a first metal, extruding a filament of a second metal onto the layer, and depositing a second layer of the first metal on the filament.
US10583870B2
Provided is a fastening component for vehicles that comprises a holding member, a nut, and a spacer. The holding member is made of a piece of plate material and bent to form first and second opposing portions that oppose each other. The nut comprises a bolt insertion hole and is arranged on an outer surface of the first opposing portion. The spacer having a cylindrical shape is arranged on an outer surface of the second opposing portion. The holding member comprises first and second through holes respectively penetrating the first and second opposing portions in respective thickness directions thereof. The first and second through holes are arranged to be continuous with the bolt insertion hole of the nut. The spacer is arranged to surround the bolt insertion hole when viewed along a central axis of the nut.
US10583866B2
A work vehicle comprising: a cab, an inside of which is a cockpit, having a window portion; a vehicle body having a passage on a periphery of the cab; a front lateral wiper provided so as to be rotatable around a first axis and along the window portion, and rotating around a second axis that extends in a different direction with the first axis in a movement range between a normal position that is in contact with the window portion and a rising position separated from the window portion; and a passage fence extending along an outer edge of the passage. The passage fence is configured to open upward with penetrating the passage fence inwardly and outwardly, and a part of the passage fence has an opening that includes the movement range of the front lateral wiper.
US10583862B2
A vehicle includes first and second roof rails spaced from each other, and a forward member and rearward member connected to each other and each extending from the first roof rail to the second roof rail. The forward member includes a beam and a finger. The finger is on the first roof rail and extends from the beam away from the rearward member.
US10583860B2
A steering arm assembly includes a steering arm body, a first rotary connecting part and a second rotary connecting part. A first end and a second end of the steering arm body are fixedly connected with a first rocker arm and a second rocker arm, respectively. The first rotary connecting part and the second rotary connecting part are respectively connected with the first end and the second end of the steering arm body, and the steering arm body is configured to rotate relative to the first rotary connecting part and the second rotary connecting part. The steering arm body is able to be detachably located on a mounting bracket through the first rotary connecting part and the second rotary connecting part; and the first rotary connecting part and the second rotary connecting part respectively include a first shaft housing and a second shaft housing, which are engaged with a first mounting plate and a second mounting plate respectively.
US10583859B2
When the state where steering torque detected by a torque detection unit is normal and the value of the steering torque is the same as or larger than a threshold value continues, an assist command generation unit that generates an assist command corresponding to steering torque produced by a driver limits the assist command; a failure determination unit includes a first failure determination unit that performs determination on a failure regardless of the limitation of the assist command and a second failure determination unit that performs determination on a failure while the assist command is limited, and stops driving of a motor when the second failure determination unit determines that there exists a failure.
US10583847B2
A raisable carrying device for loading cargo onto a rail vehicle using a hoisting unit. The carrying device includes at least one supporting unit for the cargo, holding pockets for the hoisting unit, and support surfaces for placing the carrying device directly on the floor of a terminal.
US10583845B1
Systems and methods are disclosed for detecting security threats during vehicle operations. For instance, retrieving a route plan for a route of a vehicle from a database of the vehicle; identifying either a portion of the route or a portion of the route plan as a security threat based on an analysis of the route plan; and in response to identifying the portion of the route or the portion of the route plan as the security threat, transmitting an alert of the security threat.
US10583841B2
A driving support device as an example of a data processor executes processing for estimating a driving behavior of a vehicle by using a driving behavior model trained based on detection results by a sensor. A detected-information input unit acquires detected information including the detection results. From the detection results included in the detected information input to the detected-information input unit, a selection unit selects a detection result that falls within predetermined selection range narrower than a range detectable by the sensor. A processing unit executes the processing, based on the detection result selected by the selection unit.
US10583840B2
Methods and apparatus to monitor an activity level of a driver are disclosed. An example method includes receiving, at a processor, eye movement data from a sensor monitoring eye movements of a driver of a vehicle. The method includes calculating, via the processor, an eye movement activity index using a substantially real-time recursive analysis of the eye movement data. The method further includes calculating, via the processor, a low activity indicator for the driver based on the eye movement activity index. The method also includes executing a task based on the low activity indicator.
US10583831B2
A method and a system for communicating a an ego-vehicle's determined behavior to a target object is for use in a driver assistance system of a vehicle. The method includes steps of acquiring data of a traffic scene preferably by sensor means configured to sense an environment of the vehicle, calculating a prediction result including a target object's behaviour based on the acquired sensor data, determining an action of the host vehicle based on the prediction result and generating an actuation signal for performing the determined action, and determining a communication information indicating the determined action. The communication information is output to a communication means for communication to the target object via at least one of a lighting means of the vehicle and a car-to-x communication means.
US10583828B1
Some embodiments provide an autonomous navigation system which autonomously parks a vehicle in a selected available parking space. The vehicle can be parked in a particular parking position in the parking space based on one or more factors. The particular parking position can be selected from a set of potential parking positions based on an aggregate intersection risk value associated with the particular parking position being less than at least one other potential parking position. The aggregate intersection risk value can be determined based on one or more of a proximity of one or more adjacent vehicles to the parking space, a door sweep volume of the one or more adjacent vehicles, body morphology of one or more present occupants of the vehicle, and predicted occupancy of the vehicle.
US10583826B2
Systems and methods are disclosed for controlling vehicle operations in response to a route identification reference for a vehicle based on route characteristics associated with the route identified by the route identification reference.
US10583825B2
A control apparatus for a hybrid vehicle, having an engine, an electric motor, and an automatic transmission which is placed in a selected speed position with engagement of selected at least one of coupling devices, includes: an input torque control portion controlling the electric motor for controlling an input torque transmitted to the automatic transmission during a shifting action of the automatic transmission, based on output torque of the engine and torque transmitted through the coupling devices, such that a value representing a rotating state of an automatic transmission input rotary member coincides with a target value. The input torque control portion controls the input torque to be not smaller than a predetermined lower limit, when a running state of the hybrid vehicle is switched from a power-on state to a power-off state during a shift-down action of the automatic transmission in the power-on state.
US10583824B2
A vehicle includes a left clutch provided on a path for transmitting driving torque to a left rear wheel and a right clutch provided on a path for transmitting driving torque to a right rear wheel torque. If a command value of the driving torque distributed to the left rear wheel using the left clutch and a command value of the driving torque distributed to the left rear wheel using the right clutch fall respectively below predetermined lower limit values, a control device controls the command values of the driving torque to be predetermined lower limit values. While realizing an optimal torque distribution control, accuracy of the driving torque distributed to the left and right rear wheels (auxiliary drive wheels) can be improved by preventing the command values (command torque) distributed to the left and right rear wheels from becoming small below the limit.
US10583822B2
A control system for a vehicle, the control system includes a selectable one-way clutch, a motor, and an electronic control unit. The electronic control unit is configured to (i) execute rotation control to control the motor such that negative differential rotation changes into positive differential rotation when the selectable one-way clutch is switched from a disengaged state to an engaged state while differential rotation of the selectable one-way clutch is negative and (ii) initiate engagement control by a switching mechanism such that a projecting operation of the selectable one-way clutch is completed while the differential rotation is negative.
US10583816B2
A lane departure prevention device includes: a travelling state recognition unit; a lane line recognition unit; a departure determination unit; a yaw moment calculation unit configured to calculate a target trajectory and a target yaw moment; a direction determination unit configured to determine the departure avoidance direction; a direction alignment determination unit configured to determine the turning direction of the vehicle by the target yaw moment coincides with the departure avoidance direction; and a braking force control unit configured to control the braking forces of the vehicle. In a case where the direction alignment determination unit determines that the results of determinations coincide with each other, the braking force control unit perform a braking force control, and in a case where the direction alignment determination unit doesn't determine that the results of determinations coincide with each other, the braking force control unit doesn't perform the braking force control.
US10583814B2
A method and apparatus for replacing a power source element is provided. The method includes enabling a first vehicle comprising a first power source apparatus comprising a first multiple compartment housing comprising a first plurality of receptacles retaining a first plurality of power source elements, a controller, and a communication interface. The first vehicle receives a notification indicating that a second vehicle requires replacement of a power source element of a second plurality of power source elements within a second power source apparatus of the second vehicle. The first vehicle is directed to a current location of the second vehicle and the first vehicle is docked to the second vehicle. The power source element of the second vehicle is replaced with a fully charged power source element of the first plurality of power source elements from the first vehicle during operation of the first vehicle and the second vehicle.
US10583808B2
A wiper device is provided. An operating range of each of two sets of wiper arm units can be properly restricted. A first wiper arm unit is prevented from colliding with a first front pillar or a dash panel when a first output shaft of a first speed reduction mechanism has rotated beyond a first control angle, and a second wiper arm unit is prevented from colliding with a second front pillar or the dash panel when a second output shaft of a second speed reduction mechanism has rotated beyond a second control angle.
US10583803B2
An autonomous robot vehicle in accordance with aspects of the present disclosure includes a land vehicle conveyance system, a sensor system configured to capture information including surrounding environment information and/or vehicle subsystem information, a communication system configured to communicate with a remote human operator management system, at least one processor, and a memory storing instructions. The instructions, when executed by the processor(s), cause the autonomous robot land vehicle to, autonomously, determine based on the captured information to request a remote human operator, and communicate a request to the remote human operator management system for a remote human operator to assume control of the land vehicle conveyance system, where the request includes at least a portion of the captured information.
US10583782B2
An electro-optic mirror reflective element for a rearview mirror assembly for a vehicle includes a front substrate and a rear substrate with an electro-optic medium disposed therebetween. A display element is disposed at the front substrate and includes a transparent organic light emitting diode display. With the electro-optic mirror reflective element disposed at a rearview mirror assembly at the vehicle and when the display element is activated, information displayed by the display element is viewable by a driver of the vehicle. With the electro-optic mirror reflective element disposed at the rearview mirror assembly at the vehicle and when the display element is not activated, the driver views reflected images of the scene rearward of the vehicle as reflected off a specularly reflective mirror reflector disposed at a surface of the rear substrate.
US10583774B2
A vehicle lamp emits red light from a second light emitting area by lighting a tail/accessory lamp while emitting red light from a first light emitting area during a lighting of a tail lamp. Meanwhile, the vehicle lamp lights out the tail/accessory lamp while emitting orange light from the second light emitting area during a lighting (flickering) of a turn lamp.
US10583770B2
A mechanically actuated cargo restraint system for a vehicle includes a rotatable reel in a frame, a first flexible tether, a base and a pawl. The frame includes a cog having a single tooth. The first flexible tether has a first end coupled to the rotatable reel and a second end capable of being coupled to one of a vehicle and a cargo item. The first flexible tether is windable around the rotatable reel. The base rotate with the reel. The pawl is pivotally connected to the base, and is biased in a first position that allows rotation of the pawl with respect to the cog. The pawl moves to a second position responsive to centrifugal force associated with a velocity of rotation of the rotatable reel exceeding a threshold. The pawl engages the cog in the second position to inhibit relative movement of the pawl with respect to the cog.
US10583764B1
A floor mat assembly includes an extended floor mat and a connecting floor mat. The extended floor mat includes a floor portion and an interlocking portion. The interlocking portion extends from the floor portion and includes a body, at least one first rib and at least one second rib. The body defines a channel. The at least one first rib and the at least one second rib are disposed within the channel and cooperate to form a compartment. The connecting floor mat includes a floor portion and an adapter portion. The adapter portion extends from the floor portion and includes at least one locking tab. The extended floor mat and the connecting floor mat interlock when the at least one locking tab is received in the compartment, thereby restricting lateral movement of the extended floor mat and the connecting floor mat relative to each other.
US10583756B2
A child restraint includes a juvenile seat and a seat-support base having a seat bottom and a seat back. The seat-support base is adapted to be anchored on a passenger seat of a vehicle.
US10583743B2
In a regenerative braking device of a dump truck comprising an engine, a first generator and a second generator driven by the engine, at least one travel motor driven by generated electric power of the first generator and at least one fan motor to which generated electric power of the second generator is inputted via a first rectifier circuit, the regenerative braking device comprises: a resistive element to which regenerating electric power from the at least one travel motor in regenerative braking is supplied and which is cooled by at least one fan driven by the at least one fan motor and converts electric energy into heat energy and dissipates heat; and a DC/DC converter that inputs a part of the regenerating electric power which is supplied to the resistive element to an output line of the first rectifier circuit via a second rectifier circuit.
US10583721B2
A frame and soft top assembly which includes lift assist and improved fabric management. The assembly includes a pair of front arms pivotally attached to rear side rails and are attached to the vehicle roll bar. A plurality of fabric control bows connected with pivot links provide fabric control to the top material during pivoting of the front side rails. A pair of bow pivot links are pivotally connected to the rear side rail. A rear gas strut and a front gas strut are attached longitudinally to either side of the pair of bow pivot links, one providing lift assistance at the start of the pivotal opening of the sunroof while the other of the struts gets loaded as the top is deployed and buffers the closing of the roof which also loads the strut to provide assistance in the closing direction when it is time to close the sunroof.
US10583714B2
A vehicle includes: a power equipment unit including a power equipment, a cooling mechanism for cooling the power equipment, and a case for accommodating the power equipment and the cooling mechanism; and an exhaust duct disposed on a floor panel, wherein the cooling mechanism discharges air, which has cooled the power equipment, into a passenger compartment through the exhaust duct. One end of the exhaust duct is connected to a duct connection portion of the case, and the other end of the exhaust duct is connected to a treading guard member which faces the floor panel to form a channel of air.
US10583707B2
A vehicle incorporates a gravity-assist energy harvesting suspension system including one or more gravitational positive displacement pumps. The positive displacement pump has a cylinder and a reciprocating piston inside the cylinder. The piston is adapted for movement along a compression stroke and an opposite extension stroke in response to a gravitational bounce of the vehicle when in motion. A turbine comprising a rotor shaft and attached blades is mounted relative to a distal end of a fluid outlet hose connected to the pump. Fluid discharged through the outlet hose acts on the blades, thereby moving and imparting rotational energy to the rotor shaft. A generator is operatively connected to the turbine, and is adapted for converting the rotational energy generated by the rotor shaft to electrical energy.
US10583695B2
A tire for displaying at least one indicium includes a label affixed to the tire at a mounting location. The label has a first side facing away from the tire and a second side connected to the tire. The label's first side is configured to receive at least one adhesive appliqué having at least one indicium. The mounting location is a location on a sidewall of the tire where the label undergoes a strain equal to or less than a threshold strain under pre-defined conditions.
US10583688B2
The invention relates to a wheel, especially for motor vehicles, comprising a wheel rim and a wheel disc, the wheel rim having a rim base made of fiber composite material. The invention is characterized in that the wheel disc (3, 11, 20, 29, 40) can be indirectly connected to the wheel rim (1), in particular the rim base (2), by means of a connecting element (5, 14, 22, 31, 35, 42) which is designed and associated with the rim base (2) in such a way that the connected wheel disc (3, 11, 20, 29, 40) is not in contact with the rim base (2).
US10583687B2
An apparatus and method for a reel-to-reel chalk line comprising a first housing comprising a first impregnated chalk line reel, a first rotatable crank mechanism connected to the first reel, and a first chalk bin comprising apertures for allowing the passage of a continuous impregnated chalk line. The apparatus further comprises an opposed second housing comprising a second rotatable reel, a second crank mechanism connected to the second reel, and a second chalk bin comprising apertures for allowing passage of the continuous impregnated chalk line. The continuous impregnated chalk line is reeled about the first and second reels as the respective crank mechanisms are alternately rotated forward and backward. The chalk may include a variety of substances including reactive powders, liquids, dyes, glass, minerals, plastics, ceramics, metals, and fibers. The continuous chalk line may comprise interconnected impregnated chalk lines joined by mechanical or chemical means forming the continuous impregnated chalk line.
US10583685B2
This invention relates to a method of making a sculpture from a sculpture kit which includes a container with a lid and an elongated thin, twistable, resilient or springy strip of paper-like material forming a sculpture when twisted and removably attached to the kit container lid with the container forming the base of the sculpture.
US10583679B2
A photosensitive resin printing plate precursor includes at least a substrate and a photosensitive resin layer, the photosensitive resin layer containing: (A) a partially saponified polyvinyl acetate, (B) a polyamide having basic nitrogen, (C) a compound having an ethylenic double bond, and (D) a photopolymerization initiator; the photosensitive resin layer including at least an underlayer and a printing surface layer; the substrate, the underlayer, and the printing surface layer being included in this order; and the photosensitive resin layer containing, as the partially saponified polyvinyl acetate (A), those (A1) having an average polymerization degree of 1,200 to 2,600 in the printing surface layer and those (A2) having an average polymerization degree of 400 to 800 in the underlayer.
US10583678B1
An approach for forming a multi-colored image on a substrate that includes a thermochromic material capable of producing at least two different colors is disclosed. Individually selected pixels of the thermochromic material that correspond to the image are heated to predetermined temperatures. Each predetermined temperature corresponds to a predetermined color shift of the thermochromic material. While the individually selected pixels are being heated, an area that includes the individually selected pixels is flooded with an amount of UV radiation sufficient to at least partially polymerize the thermochromic material. A color of each individually selected pixel is determined by a predetermined temperature to which the pixel is heated and the amount of UV radiation to which the pixel is exposed.
US10583675B2
Examples systems and methods of this disclosure include a threshold corresponding to a vapor density, and a circuit or method step to compare an incoming signal that corresponds to a detected vapor density with the threshold.
US10583667B2
The disclosure discloses a printer including a feeder, a printing, a communication device, and a controller. The controller is configured to execute a temperature reception process and a printing control process. In the temperature reception process, first temperature data is received. The first temperature data is broadcast-transmitted from at least one other printer and corresponds to a first temperature inside the other printer. In the printing control process, a feeder and a printing head are controlled on the basis of the first temperature data to form a print on a printing medium and thereby generate a printed matter.
US10583663B2
A liquid-consuming apparatus includes: a tank including a liquid storage chamber which stores a liquid, an inlet formed in a surface of the tank, and an outlet through which the liquid from the liquid storage chamber flows; a cap which is movable between a first position and a second position; a cover which is movable relative to the tank between a closed position and an open position; and a holding member which is connected to the cap and which holds the cap at the second position. The cap at the second position or the holding member is configured to obstruct a movement of the cover from the open position to the closed position.
US10583657B2
A liquid jetting apparatus includes individual channel rows each formed by individual channels aligned in a first direction and including nozzles respectively, the individual channel rows being arranged in a second direction orthogonal to the first direction, first manifolds each extending in the first direction and connected to the individual channels, the first manifolds being arranged in the second direction, and at least one second manifold extending in the first direction and connected to the individual channels. First connecting ports are formed in end portions, of the first manifolds, on one side in the first direction and open on one side in a third direction orthogonal to both the first direction and the second direction. A second connecting port is formed in an end portion, of the second manifold, on the one side in the first direction and open on the one side in the third direction.
US10583655B2
A liquid ejection device is disclosed. One device includes a plurality of contacts aligned along a first direction. The plurality of contacts are positioned between two piezoelectric-element rows of four piezoelectric-element rows in a second direction orthogonal to the first direction. Each of the two piezoelectric-element rows is closer to a center line of a first substrate with respect to the second direction than each of another two piezoelectric-element rows of the four piezoelectric-element rows in the second direction. Each of a plurality of piezoelectric elements of a four piezoelectric-element rows is individually connected with a corresponding one of the plurality of contacts, respectively. One of the plurality of piezoelectric elements of the another two piezoelectric-element rows connect with a corresponding one of the plurality of contacts.
US10583647B2
Systems and methods for controlling warping and/or curling in a 3D-printed component are disclosed. One method may include fabricating a component having one or more anchors attached thereto layer-by-layer via additive manufacturing. The component and anchor(s) may be formed of a first material. The method may also include fabricating a support structure to support portions of the component as it is fabricated. The support structure may at least partially enclose the anchor(s). The anchor(s) and the support structure may be removed from the component after it is fabricated. Each anchor may be the same size and shape, which may reduce design time and allow the same anchor design to be used across multiple components. The support structure enclosing the anchors may lock them into place and prevent the component from warping or curling, for example, due to expansion or contraction during cooling.
US10583642B2
A honeycomb structural body includes multiple cores, at least face sheet, and at least one reinforcement sheet. The multiple cores each have a honeycomb structure, and are bonded to each other with foamed adhesive in a direction in which the number of multiple pores formed by the honeycomb structure increases. The at least one face sheet is adhered to the multiple cores so as to cover the multiple pores. The reinforcement sheet is placed between the multiple cores and the at least one face sheet, at a position where the reinforcement sheet covers the foamed adhesive.
US10583636B2
Soft touch fire retardant laminates with PVC middle layers, foamed or unfoamed, and multiblock copolymer or polyurethane or silicone top layers which meet FAA requirements are disclosed.
US10583635B2
The present invention provides a decorative sheet capable of vividly displaying deep-color designs including raven blackness. The decorative sheet includes a base material, and at least a protective layer, a primer layer, and a decorative layer laminated in this order on the base material, wherein the decorative layer contains a black pigment and the primer layer is formed of a cured product of a resin composition containing a resin A having a hydroxyl value of 44 mgKOH/g or less.
US10583632B2
Coatings and materials that are atomic oxygen resistant and have an atomically smooth surface that can reduce drag are disclosed. The coatings and materials can be used on at least a portion of a spacecraft intended to operate in harsh environments, such as stable Earth orbits at about 100 km to about 350 km.
US10583629B2
A joining structure includes a first member, a second member of a material different from that of the first member, and a separation mechanism provided between the first member and the second member and that separates the first member and the second member from each other, wherein a resin is filled into the space between the edge of at least one member among the first member and the second member, and the other member.
US10583617B2
A method and an automatic layup system for making a stack of a plurality of composite plies are presented. The automatic layup system includes a stacking assembly located in a first plane and a layup tool located in a second plane parallel to the first plane. The stacking assembly and the layup tool are movable towards each other. The method includes the steps of (a) providing one or more composite sheets between the layup tool and the stacking assembly, (b) generating a first composite ply from the one or more composite sheets, (c) placing the first composite ply on the layup tool by the stacking assembly by bringing the stacking assembly and the layup tool close to each other, and (d) repeating the steps (b) and (c) for generating and placing a second composite ply on the first composite ply, which is placed on the layup tool.
US10583615B2
A dry, fibrous tape for use in an automated placement process such as ATL or AFP and a preform produced therefrom. The preform is configured for resin infusion. The tape contains a layer of unidirectional fibers, at least one nonwoven veil bonded to one side of the fiber layer, and at least binding materials present within the tape. The preform produced from laying down such tape exhibits a low-bulk property that is close to the final thickness of the cured fiber-reinforced resin article and no further consolidation or compaction is required.
US10583598B2
An injection molding apparatus comprising: an injection molding machine, a heated manifold, a nozzle, the downstream end of the nozzle comprising an inner tubular member having a central flow channel and an outer circumferential surface and an outer tubular member having an inner tubular surface, the outer tubular member forming a seal surrounding the gate, the inner and outer tubular members being adapted to form a sealed circumferential gap, the inner tubular member including one or apertures extending radially through the inner tubular member to route flow radially from the fluid flow channel into the circumferential gap.
US10583594B2
A process for manufacturing a transaction card includes forming an opening in a card body of the transaction card; inserting an electronic component into the opening; and molding a molding material about the electronic component. A transaction card includes a molded electronic component.
US10583588B2
A retaining wall block having a false joint and a system of retaining wall blocks. The retaining wall block includes a body having a first textured surface and a second textured surface and a false joint dividing the first and second textured surface. The false joint can have a depth divided by the width greater than two inches. The false joint can have an interior angle of less than ten degrees. The system includes a plurality of retaining wall blocks and a first course of retaining wall blocks engaged with a second course of retaining wall blocks below. Each block in the system comprising a front face having a first textured surface and a second textured surface and a false joint dividing the first and second textured surface. The false joint can extend a predetermined depth of a third surface.
US10583582B2
A control method for a core drill and a feed device for driving the core drill along a machine holding device, including the method steps: moving the core drill in a first direction; detecting the surface position of a material based on reaching a threshold value for at least one feed device parameter as a first reference value; moving the core drill in a second direction; operating the core drill in a tapping mode; moving the core drill in the first direction; detecting the surface position of a material based on reaching a threshold value for at least one corresponding drilling parameter as a second reference value; activating a water supply; and activating a regulating and control unit for adapting at least one drilling parameter as a function of at least one parameter of the feed device. A feed device for driving a core drill along a machine holding device for the use of the method, a core drill for the use of the method, as well as a core drilling system including a core drill and a feed device for driving the core drill along a machine holding device for the use of the method.
US10583576B2
A heating element for a shaving razor having an insulating member with a base and at least one electrical terminal. A flexible printed circuit board having a base with at least one electrical terminal electrically and mechanically coupled to the corresponding electrical terminal of the insulating member. A non electrically conductive underfiller encapsulant is positioned between the base of the insulating member and the base of the flexible printed circuit board to provide a water tight seal around the electrical terminals.
US10583570B2
A displacement measurement device includes a first structure, a second structure, and a coupling portion configured to couple the first structure with the second structure. The first structure includes a first sensor configured to generate an electrical signal corresponding to displacement between a first attachment portion of the first structure and a second attachment portion of the second structure in the at least one first direction. The second structure includes a second sensor configured to generate an electrical signal corresponding to displacement between the first attachment portion and the second attachment portion in the at least one second direction.
US10583559B2
A humanoid robot which is capable of surveying its environment, notably to determine when humans are present and to engage in Activities with humans corresponding to an evaluation of their desires is provided. An operating system of the robot is configured in the robot to process the information received by Extractors (sensors and processing capabilities), to list Activities (gestures, dialogs, etc. . . . ) which are prioritized as a function of the current conditions and the history of engagement with the humans, to decide which Activity is to be launched and to have Actuators execute the Activity. Safeguard conditions of the robot are also taken into account in the list of Activities to be performed.
US10583557B2
A robotic system includes a jointed mechanism, position sensors, and a controller. The mechanism has an end-effector, and further includes actively-controlled joints and passive joints that are redundant with the actively-controlled joints. The position sensors are operable for measuring joint positions of the passive joints. The controller is in communication with the position sensors, and is programmed to execute a method to selectively control the actively-controlled joints in response to the measured joint positions using force control and/or a modeled impedance of the robotic mechanism. Possible control modes in impedance control include an Autonomous Mode in which an operator does not physically interact with the end-effector and a Cooperative Control Mode in which the operator physically interacts with the end-effector.
US10583556B2
One embodiment provides a method, including: detecting, using at least one sensor, a displacement event associated with a monopod jib, wherein the displacement event moves a portion of the monopod jib from a first position to a second position; calculating, using a processor, an adjustment value for at least one of a plurality of motors of a stabilization mechanism operatively coupled to the monopod jib, wherein the calculated adjustment value identifies a motor movement to counteract the displacement event; activating the at least one of a plurality of motors corresponding to the calculated adjustment value; and adjusting, using the activated at least one of the plurality of motors, at least one portion of the stabilization mechanism using the calculated adjustment value. Other embodiments are shown and described.
US10583549B2
A method for manufacturing a handle includes manufacturing a surface portion for the handle, arranging the surface portion having a uniform thickness in a mould to contact a surface of the mould and to cover cavities which are provided in the surface in a predetermined pattern, pressing those parts of the surface portion that cover the cavities into the cavities with a mass that is introduced into the mould, and removing the handle from the mould once the mass has cured to form a rigid body which is at least partly covered by the surface portion from which protrusions arranged in the predetermined pattern protrude.
US10583547B2
A method and a system for controlling injection processes in liquid fuel-operated setting devices is provided wherein a time-controlled metering device supplies fuel from a fuel tank to a combustion chamber. In order to further improve control of injection processes in the liquid fuel-operated setting devices, a metering time interval of the time-controlled metering device is adapted to the age of the fuel tank.
US10583546B2
The present invention provides a removal tool. A base portion is used as a base, and a first component and a second component are separately disposed on the base portion in a manner of being isolated from each other, so that a relative distance between the first component and the second component can be changed under the effect of an external first external force, to enable a vehicle maintainer to perform removal work of separating a ball joint of a lower support arm of a vehicle from a combined bushing. The technical features of the present invention further include a first acting portion, a second acting portion, and a third acting portion respectively disposed on the first component and the second component. The first acting portion and the second acting portion are disposed on a same component, and the first component is enabled to change relative positions of the first component and the second component under the effect of an external second external force, so that relative positions among the first acting portion, the second acting portion, and the third acting portion are changed. As such, the vehicle maintainer can choose the first acting portion and the second acting portion or choose the first acting portion and the third acting portion according to an actual requirement, to adapt to requirements of different conditions of removal work.
US10583539B2
A magnetic drill press includes a housing, a magnetic base coupled to the housing for engagement with a workpiece, and a motor carriage slidably coupled to the base housing. The magnetic drill press further includes an electric motor supported by the motor carriage and configured to rotate a bit about a bit axis, and a spindle assembly supported by the housing and coupled to the motor carriage for selectively positioning the motor carriage relative to the housing. The magnetic drill press further includes a handle hub coupled to the spindle assembly, and a ratchet assembly including a ratchet head coupled to the handle hub and a ratchet handle coupled to the ratchet head for actuating the spindle assembly by reciprocating motion of the ratchet handle.
US10583536B2
A method for fabricating vacuum tooling is disclosed using porous granular media. A sheet of steel webbing is affixed to a frame. A plurality of layers of fiberglass is affixed to the webbing. A vacuum port is installed through the webbing and plurality of layers of fiberglass. A granular media is mixed with epoxy to form a granular mixture. The granular mixture is layered over the plurality of layers of fiberglass to form a flat surface and machined for uniformity before sealing.
US10583535B2
A heat exchanger and a method for additively manufacturing the heat exchanger are provided. The heat exchanger includes a housing defining a heat exchange plenum having a first fluid inlet and a first fluid outlet separated along a transverse direction. A plurality of heat exchange banks pass through the heat exchange plenum between a top side and a bottom side of the housing substantially along a vertical direction, each of the heat exchange banks comprising a plurality of heat exchange tubes. A plurality of collector manifolds are positioned at the top side and the bottom side of the housing, each collector manifold defining one or more connecting ports providing fluid communication between adjacent heat exchange banks.
US10583532B2
A metal powder additive manufacturing system and method are disclosed that use increased trace amounts of oxygen to improve physical attributes of an object. The system may include: a processing chamber; a metal powder bed within the processing chamber; a melting element configured to sequentially melt layers of metal powder on the metal powder bed to generate an object; and a control system configured to control a flow of a gas mixture within the processing chamber from a source of inert gas and a source of an oxygen containing material, the gas mixture including the inert gas and oxygen from the oxygen containing material.
US10583527B2
A welded shaped steel manufacturing device includes: a plate conveying device configured to convey a web member and two flange members in a conveyance direction; and a laser welding device configured to laser-weld butt portions of ends of the web member butting against the two flange members for weld-bonding, wherein the plate conveying device includes a web member holding device having surface side rollers arranged at intervals in the conveyance direction in a position not to block laser irradiation from the laser welding device toward welding points, and wherein the web member is held with the surface side rollers over a predetermined range in the conveyance direction, and wherein side ends of the surface side rollers facing the two flange members are positioned along boundaries of areas having spatters dispersed from the welding points in a degree exceeding a predetermined value.
US10583526B2
Systems for processing a material by submerging the material in a fluid and directing laser pulses at the fluid and the material for processing the material. An embodiment removes the surface of concrete, brick, or rock or minerals in a relatively gentle, energy-efficient, and controlled manner that also confines the material that is removed.
US10583525B2
A laser processing machine includes a beam parameter product variable device, and a beam diameter variable device. The beam parameter product variable device sets beam parameter products of a laser beam to a predetermined value. The beam diameter variable device includes a first lens that is movable in an optical axis direction and having a positive focal length, and converts divergent light of a laser beam emitted from an emission end of the laser beam into convergent light, and a second lens that is movable in the optical axis direction and having a negative focal length on which the convergent light is incident. A third lens having a positive focal length, focuses the laser beam emitted from the beam diameter variable device, and irradiates a plate material with the focused laser beam.
US10583523B2
Methods of circumscribing defects in optical devices are described. A perimeter is formed about a defect by laser ablation, where the perimeter electrically isolates the defect. The perimeter does not have damage due to excess energy from the laser and thus does not create new electrical shorts.
US10583519B2
A friction stir welded structure includes first and second members. The first member has a base defining opposed first and second surfaces, and spaced first and second walls extending outwardly from the second surface of the base to define a receptacle therebetween. The second member includes an elongate rib extending from a root portion to a first tip portion, the root portion having a uniform root portion thickness and the first tip portion having a first tip portion thickness not greater than the root portion thickness. The first tip portion is sized for insertion into the receptacle and shaped conformally with the receptacle so that the first tip portion engages a closed end of the receptacle. A friction stir weld joint extends through the base and at least portions of the first and second walls of the first member and into the first tip portion of the second member, thereby to join the first and second members.
US10583517B2
This invention effectively suppresses the generation of scattered electrons such as secondary electrons and backscattered electrons. A three-dimensional laminating and shaping apparatus includes a linear funnel that recoats a material of a three-dimensional laminated and shaped object onto a shaping surface on which the three-dimensional laminated and shaped object is to be shaped. The three-dimensional laminating and shaping apparatus also includes an electron gun that generates an electron beam. The three-dimensional laminating and shaping apparatus further includes an anti-deposition cover made of a metal and formed between the shaping surface and the electron gun. In addition, the three-dimensional laminating and shaping apparatus includes a DC power supply that applies a positive voltage to the anti-deposition cover.
US10583515B2
A welding torch maintenance apparatus and a welding tip changer are described. The welding torch maintenance apparatus and the welding tip changing apparatus each comprise a first gripping means for fastening the welding torch/diffuser so that the nozzle/welding tip is aligned with the rotational axis, a second gripping means for holding the nozzle/welding tip, the second gripping means rotates about the rotational axis to remove the nozzle/welding tip, and moves along the rotational axis. A drive means is provided for rotating the second gripping means, and a lift system is provided for moving the second gripping along the rotational axis. The welding torch maintenance apparatus further includes a cleaning means which enters the nozzle at the distal end and cleans an interior of the nozzle.
US10583514B2
A welding torch system includes a diffuser assembly that includes a locking mechanism to receive a contact tip. Additionally, the welding torch system includes the contact tip, which includes locking elements configured to interact with the locking mechanism of the diffuser assembly to secure the contact tip within the diffuser assembly. Further, the contact tip is rotated within the diffuser assembly to securely align the locking elements with the locking mechanism.
US10583504B2
Two 18V-type rechargeable batteries (31 and 31) are attached in series so as to allow a 36V-type tabletop cutting device (C1) to be utilized. By utilizing the 18V batteries which are highly prevalent for electric tools, it is possible to use the 36V-type tabletop cutting device (C1) as well as to reduce costs for the batteries.
US10583502B2
Provided is a cutting insert capable of suppressing edge fracture when a work having high hardness is machined. A cutting insert includes two end surfaces having a plurality of corner parts and opposed to each other, a peripheral side surface extending between the two end surfaces, and a cutting edge formed at an intersecting edge between at least one of the two end surfaces and the peripheral side surface. The cutting edge has at least a first corner edge, a second corner edge, a major cutting edge, and an end cutting edge. The end cutting edge has a circular-arc shape, which projects outward, as viewed from the side of the end surface. The end cutting edge has a width which is from 15% to 50% of the width of the cutting insert. The end cutting edge has an arc radius which is from ⅓ to 1/1 of the width of the cutting insert.
US10583487B2
A method of producing a finished essentially 100% dense homogenous alloyed metallic product. First, a metal powder is provided comprised of particles with each particle having a predetermined alloy content. Next, the metal powder is blended with a mixture of a lubricant and a binder to form a composite powder. That composite powder is then compacted in a compacting die at room temperature to form a green part. The lubricant and binder are then removed by heating the green part to at least a first temperature profile in a confined atmosphere with a predetermined dew point profile. Next, the remaining green part is heated to a second temperature higher than the first temperature and with predetermined dew point and H2/H2O ratio in a furnace atmosphere to remove surface oxides from the part. Finally, the part is densified into a finished or near net shape homogenous alloyed product.
US10583483B2
A pivoted powder pushing device is provided, comprising a first portion and a contact member, wherein: the contact member is configured to operatively engage a grip arm of the distribution member when the distribution member is positioned at least in part above the base surface, and the first portion is moved via the engagement of the grip arm and the contact member in a first direction opposite a direction of travel of the distribution member, such that the first portion of said pivoted powder pushing device passes under said distribution member. An associated apparatus, method, and computer program product are also provided.
US10583482B2
A modular system (1) for producing a three-dimensional object (2) by layerwise application and selective solidification of a pulverulent build material (13) contains a first module (30, 34-36; 40, 41) suitable for carrying out a first process used for the production of the three-dimensional object (2), and at least a second and a third module (30, 34-36; 40,41) suitable for carrying out a further process used for the production of the three-dimensional object (2). The first to third modules (30, 34-36; 40, 41) are configured so that the second or the third module, or both, can selectively and replaceably be connected to the first module in such a way that their housings are coupled to one another directly.
US10583480B2
The invention relates to a ceramic and/or metal powder press, comprising a die (1) with a die surface (1o) and a die opening (2) for filling in and compressing a material, a fill shoe (3) arranged to be moveable along a travel path (4) across the die surface (1o) for filling the material (p), and feed tubes (7, 8) connected with the fill shoe (3) for filling the material into or via the fill shoe (3), wherein at least two such feed tubes (7, 8) are connected to the fill shoe (3) from a direction lateral to the travel path. The invention also relates to a method for compressing a compact (12) of a metallic and/or ceramic powder and/or granular material (p) in such a ceramic and/or metal powder press.
US10583478B2
A method of providing datum features on a ceramic article including the steps of providing a ceramic member having a plurality of substantially parallel holes extending into the ceramic member. Providing a plurality of tubular mounts, the cross-sectional area of each tubular mount being less than the cross-sectional area of the corresponding hole. Applying adhesive to the exterior surface of each one of the tubular mounts and inserting an adhesive covered tubular mount into each one of the holes. Providing a fixture member having a plurality of substantially parallel projections extending from predetermined positions. Positioning the ceramic member on the fixture member such that each projection locates in one of the tubular mounts and fixes the tubular mounts at the predetermined positions. The ceramic article may be removed from the fixture member or located in a machine tool using the fixture member and machining the ceramic article.
US10583463B2
Aspects of the subject disclosure may include, for example, a system for detecting an accumulation of a liquid on a transmission medium that may interfere with the propagation of guided electromagnetic waves on a surface of the transmission medium, and directing a device to remove at least a portion of the liquid accumulating on the surface of the transmission medium to mitigate the interference. Other embodiments are disclosed.
US10583462B2
A method of producing an electromechanical transducer includes forming an insulating film on a first electrode, forming a sacrificial layer on the insulating film, forming a first membrane on the sacrificial layer, forming a second electrode on the first membrane, forming an etching-hole in the first membrane and removing the sacrificial layer through the etching-hole, and forming a second membrane on the second electrode, and sealing the etching-hole. Forming the second membrane and sealing the etching-hole are performed in one operation.
US10583460B2
Provided is a method for forming a multilayer coating film giving excellent low temperature impact resistance to a substrate that comprises a metal material and a plastic material. The method for forming a multilayer coating film comprises sequential steps of forming an uncured primer coating film, an uncured first colored coating film, an uncured second colored coating film and an uncured clear coating film on a substrate; and heating the same so as to simultaneously cure these 4 coating films, wherein the aqueous first colored paint and aqueous second colored paint are each a 1-package type paint composition containing a specific hydroxyl group-containing resin and a specific blocked polyisocyanate compound.
US10583451B2
Disclosed is a work booth safety system for an automotive body repair shop including a work booth with a ventilation system for evacuation of polluted air and an entrance closed or opened by a door or drape. The work booth is configurable into three different work modes: 1) For preparative dent repair, the entrance is kept open and electrical sockets and compressed air supply is deactivated. Ventilation air flow is mainly directed in a horizontal direction and evacuated through a wall ventilation outlet duct. 2) For spray application of a body sanding foundation, the entrance is closed and electrical sockets are deactivated, the compressed air supply is activated, and the ventilation air flow matches that of work mode 1. 3) For welding, the entrance is closed and electrical sockets are activated. The compressed air supply is deactivated and the ventilation air flows vertically upward through a roof ventilation outlet duct.
US10583450B2
In a dispenser for dosing of at least one component received in a receiving compartment, a valve device, forming an inlet valve and an outlet valve associated with an outlet opening, is formed of at least two valve elements.
US10583435B1
A specimen processing cartridge includes a reservoir having a fluid inlet, an elastic diaphragm, and a fluid outlet. The reservoir is operable to receive a volume of liquid from the fluid inlet, and the fluid outlet is positioned along a fluid flow path between the reservoir and a downstream reservoir. The cartridge includes a dissolvable membrane that occludes flow through the fluid outlet when the dissolvable membrane is in a first, undissolved state, and that permits flow from the reservoir to the downstream reservoir when in a second, dissolved state. The elastic diaphragm is operable to pressurize the reservoir upon receiving the volume of liquid when the dissolvable membrane is in the first, undissolved state, and is operable to contract and propel at least a portion of the volume of liquid from the reservoir to the downstream reservoir when the dissolvable membrane is in the second, dissolved state.
US10583432B2
A sampling module of a fluid processing apparatus includes at least one multi-configuration device connected to a filtration module. The invention relates to an area of non-disruptive sampling from any flow stream including the ones containing solids. The fluid processing apparatus remains in fluid communication with a sample processing module in all configurations of the sampling module and the parameters deemed critical for a chemical process remain unaffected during the sampling event. The entire event is controlled from a computer and the results are collected to make decisions on analytical and process controls.
US10583430B2
An ion exchange membrane having a structure that an ion exchange resin is filled in spaces of a porous base film, the porous base film has a structure that at least two porous olefin resin layers are laminated with a bonding strength of 100 gf/cm or more to less than 700 gf/cm and a Gurley air permeance of 500 sec/100 ml or less in terms of a 100 μm thick film. In this ion exchange membrane, base film has high air permeability though it has a multi-layer structure that a plurality of porous resin films are bonded together, and therefore a rise in electric resistance caused by the lamination of the base sheets is effectively suppressed.
US10583429B2
The present disclosure is directed to mixed mode chromatography media comprising a ligand directly attached to a solid support. In some aspects, the ligand has a chemical formula of The mixed mode chromatography media is useful for binding and purifying proteins from a solution.
US10583426B2
A catalyst and process for the production of methyl acetate by contacting dimethyl ether and carbon monoxide in the presence of a catalyst which is a zeolite of micropore volume of 0.01 ml/g or less.
US10583423B2
Embodiments of processes for producing propylene utilize a dual catalyst system comprising a mesoporous silica catalyst impregnated with metal oxide and a mordenite framework inverted (MFI) structured silica catalyst downstream of the mesoporous silica catalyst, where the mesoporous silica catalyst includes a pore size distribution of at least 2.5 nm to 40 nm and a total pore volume of at least 0.600 cm3/g, and the MFI structured silica catalyst has a total acidity of 0.001 mmol/g to 0.1 mmol/g. The propylene is produced from the butene stream via metathesis by contacting the mesoporous silica catalyst and subsequent cracking by contacting the MFI structured silica catalyst.
US10583422B2
In an aspect, a method for the aromatization of hydrocarbons comprises contacting a hydrocarbon feedstream with a catalyst; wherein the catalyst comprises a zeolite comprising Si, Al, and Ge in the framework with Pt deposited thereon; wherein the zeolite further comprises Na; and wherein the catalyst has an Si:Al2 mole ratio of greater than or equal to 125, an Si:Ge mole ratio of 40 to 400, and an Na:Al mole ratio of 0.9 to 2.5, wherein the catalyst has an aluminum content of less than or equal to 0.75 wt % excluding any binder and extrusion aide.
US10583421B2
These embodiments relate to a method of attaching photocatalytic materials to inorganic surfaces. A method is described wherein metal hydroxide is converted to metal oxide, creating metal oxide linkages to attach photocatalysts to an inorganic surface. The photocatalyst attached inorganic material is useful in products that can partially or fully oxidize certain volatile organic compounds from a gas or liquid stream.
US10583414B2
Apparatus and methods for using a flow cell array are provided herein. A method includes determining placement of multiple reaction site openings, wherein each reaction site opening is connected to a first sub-surface channel; connecting the first sub-surface channel to two or more additional sub-surface channels by multiple vias; and providing a material for multiple reaction sites, wherein an overlap of the multiple reaction site openings and the material delineate the multiple reaction sites.
US10583409B2
The system and method of the invention pertains to an axial flux stator is implemented to replace the drive-end magnets and the drive motor. The axial flux stator comprises a control circuit to control the voltage and current provided to the stator, to measure the torque and speed of rotation, and to measure the magnetic flux and magnetic flux density produced by the axial flux stator and impeller magnets, individually or in combination. The axial flux stator comprises a plurality of current carrying elements to produce magnetic flux in an axial direction and drive the impeller.
US10583407B2
This invention relates to barrier materials comprising reduced graphene oxide, methods of making said materials and their uses. The reduced graphene oxide is preferably formed from the reduction of graphene oxide by HI, HBr or ascorbic acid.
US10583400B2
Membrane elements that use multiple membrane leaves may have a limited total active membrane area due to an increased diameter at the ends of the element. Membrane leaves may comprise a permeate carrier positioned between one or more membrane sheets. Adhesive may be used to seal one or more edges of the membrane leaf. The membrane sheets, permeate carrier and the adhesive contribute to the thickness of the edges of the membrane leaf and the diameter at the ends of the element. A reduced thickness of the edges of the permeate carrier may reduce the diameter at the ends of an element. Another permeate carrier sheet may also be used that is distanced from at least one edge of the membrane sheet so the permeate carrier sheet does not contribute towards the increased diameter at the ends of the element.
US10583397B2
Systems and methods used to control tangential flow filtration are provided, including control systems and methods for use with connected systems with upstream processing units, such as chromatography processing units, in fluid communication with a tangential flow filtration processing unit. Also included are control systems and methods for performing continuous concentration using single-pass tangential flow filtration with permeate flow control.
US10583395B2
The present disclosure is directed to a forward osmosis system/process utilized primarily in conjunction with a subsurface irrigation system/process. Saline wastewater or naturally saline water is treated using forward osmosis membranes that draw at least partially purified water from the wastewater into an osmotic draw solution (draw solution). The resulting diluted osmotic draw solution is then circulated through the subsurface irrigation system including one or more tubular membranes that reject the draw solution while permitting water in the diluted draw solution to pass through.
US10583391B2
An absorbent apparatus is provided for an air dryer purge air cleaner. The absorbent apparatus comprises a volume for containing absorbent material. The absorbent apparatus also comprises absorbent material that is both oleophilic and hydrophobic and is packed in the volume to provide a packed bed of absorbent material with a predetermined packing density.
US10583390B2
Organosilicon compounds in a process exhaust stream from silicone production are removed by contacting the exhaust stream with a semipermeable silicone membrane which is selectively permeable to organosilicon compounds and oxygen relative to nitrogen. The pressure on the permeate side of the membrane is preferably less than the pressure on the retentate side.
US10583388B2
A method for capturing CO2 comprising dissolving at least one pure amino acid (AA) in water without the use of a catalyst for establishing protonation of an amino group of the amino acid, adding at least one base solution to the amino acid and water solution to deprotonate the protonated amino group of the amino acid and forming an amino acid-XOH—H2O wherein X is sodium or potassium, and subjecting CO2 to the amino acid-XOH—H2O to form new nanomaterials is provided. A regenerable nanofiber is disclosed comprising a NaHCO3 nanofiber, a KHCO3 nanofiber, or an amino acid nanofiber made from subjecting a CO2 gas to an amino acid aqueous solvent. Preferably, the amino acid aqueous solvent is one or more of a Gly-NaOH—H2O, an Ala-NaOH—H2O, a Phe-NaOH—H2O, a Gly-KOH—H2O, an Ala-KOH—H2O, and a Phe-KOH—H2O.
US10583378B2
Embodiments of the invention provide a filter for use in filtering a fluid slurry that includes particles of varying size, such as pool water including debris. The filter is in electrical communication with a sensor and includes a housing having an inlet to receive the fluid slurry, an outlet, and an internal chamber. An actuator can be coupled to the filter media to move at least a portion of the filter media to vary a dimension of the pores. The filter also includes a controller connected to the actuator that is capable of receiving a signal from the sensor and controls the actuator to change the dimension of the pores based on the signal.
US10583374B2
A system operating as a centrifugal, liquid-liquid separator may be controlled, and even optimized, by automatic control of back pressure to establish an optimum position of the dispersion band therein. Optimizing to minimize impurities (from each other) in each of two separated phases is possible, even simultaneously, by reliance on a processor setting the settling lengths of both heavy and light phases at the same value. Settling length, defined in accordance with the invention, reflects a settling velocity multiplied by a residence time. Equating these lengths, for droplets of each in the other liquid, provides superior results over conventional settling theory maximizing settling area. Equalization of residence times did not provide an improvement over conventional settling theory.
US10583366B2
A method for an online video game or application service system includes running a video game or application on an application host server at a data center, an uncompressed video stream being produced therefrom. The uncompressed video stream is encoded into compressed video stream, which is then transmitted over the Internet to an output client device of a user. The output client device decompresses the compressed video stream and displays live video on a screen. User control input transmitted from an input client device is delivered to the application host server. The user control input includes game or application commands. The input client device is associated with the user and is separate from the output client device. Responsive to receiving the game or application commands, the application host server generates a new uncompressed video stream.
US10583363B2
In a game apparatus, a game program and a web browser program are stored. In a web browser process, a predetermined web page is displayed, first access destination information is acquired on the basis of a user operation, and the first access destination information is outputted to be usable in the game process. In a game process, a server is accessed on the basis of the first access destination information, a predetermined content corresponding to the first access destination information is acquired, and the game process is executed using the predetermined content.
US10583361B2
Systems, methods and articles of manufacture for controlling devices in a synchronized fashion. Embodiments include determining one or more environmental devices are available within a physical environment. A first interactive game that is playing within the physical environment is detected. Embodiments determine an environmental condition during a first playback event within the first interactive game. The one or more environmental devices within the physical environment are then controlled during playback of the first playback event within the first interactive game, based on the determined environmental condition.
US10583353B2
A communication system may include a server having a memory and processor, mobile wireless communications devices in communication with the server, a given mobile wireless communications device, and a given activity tracker device carried by a respective user of the given mobile wireless communications device. The given mobile wireless communications device may be configured to execute an online card game with other mobile wireless communications devices via the server, wirelessly communicate with the given activity tracker device for monitoring an athletic activity of the respective user of the given mobile wireless communications device, and communicate with the server and cause the online card game to deal a card when the respective user exceeds an athletic activity threshold.
US10583349B2
Card handling systems include shuffling devices, shoe devices, and a card transfer system for automatically transferring cards from the shuffling device into the shoe device. Shuffling devices may include a divider configured to contact at least one card positioned within a compartment of the shuffling device. Shoe devices may include a card loading system for loading cards into a card storage area through an opening in a base of the shoe device. Methods of providing cards during a casino table game play include identifying card information including a rank and a suit of each card in a shuffling device and a shoe device and transporting cards from the shuffling device to the shoe device.
US10583348B2
A card game includes a deck of cards used, for example, to play craps, poker, or any combination thereof.
US10583347B2
The present document describes a blade sharpening system comprising a blade sharpening device, a blade holding apparatus and a controller operatively coupled to the blade sharpening device and said blade holding apparatus to control sharpening of said blade, and methods of using the same.
US10583338B2
Embodiments of grooves of golf club heads and methods to manufacture grooves of golf club heads are generally described herein. Other embodiments may be described and claimed.
US10583324B2
Described is a system for prediction of adversary movements. In an aspect, the system includes one or more processors and a memory, the memory being a non-transitory computer-readable medium having executable instructions encoded thereon, such that upon execution of the instructions, the one or more processors perform operations of computing relative positions of multiple objects of interest, generating a feature representation by forming a matrix based on the relative positions, predicting movement of the multiple objects of interest by applying clustering to the feature representation and by performing canonical correlation analysis, and controlling a device based on the predicted movement of the multiple objects of interest.
US10583323B2
An exercise device comprises adjustable apparatus for engaging the feet of a user, including sole-support members positioned for receiving the soles of a user's feet, an adjustable heel engaging member that is positioned to be adjusted relative to the sole-support members, and a pivotally adjustable member positioned to engage the top of a user's feet, and further including one or more members for adding weights to the device.
US10583318B2
A dumbbell to be used as a weight training device during an exercise program. The dumbbell includes a gripping handle and a pair of collars connected to opposite ends of the handle. A series of weight plates having different weights are selectively and detachably connected to each other and to the pair of the collars so as to enable a user to incrementally adjust the gross weight of the dumbbell to conform to his exercise program. Each weight plate has a recessed V-shaped coupling slot formed in one face thereof and a V-shaped coupling body projecting from the opposite face. The V-shaped coupling body of a first weight plate being carried by the dumbbell is aligned with and guided into receipt by the V-shaped coupling slot of an adjacent additional weight plate so that the first and additional weight plates can be detachably connected together.
US10583312B2
A treatment bed arranged in a tip direction of an irradiation nozzle and constructed movably, a treatment information system that manages prescription data, a treatment control system that receives a target position stored in the treatment information system to cause a main display system to display the target position, a pendant to input a movement command for the treatment bed, the main display system that receives the target position of the treatment bed from the treatment control system and displays an actual position of the treatment bed, and a patient positioning support system that calculates correction values for the target position thereof to provide the correction values to the treatment control system and the pendant are included, wherein the treatment control system sends the target position thereof to the treatment information system at a period shorter than an operation sequence thereof and stores initial values to be sent in advance.
US10583310B1
An implant planning system aids delivery of radiation to tumor sites of a patient. The system allows a user to test various combinations of virtual implants, each associated with a corresponding physical implant (e.g., a carrier with an embedded radioactive seed), and to view the dosage area of the virtual implants so that adjustments to the virtual implants may be made until a prescribed dose of radiation to a treatment area is achieved. A treatment plan developed based on the virtual implants may then be used in surgical implantation of the corresponding physical implants. For example, the implant configuration of the treatment plan may be projected onto a treatment surface of a patient, such as in a surgical room, so that physical implants may be placed according to the projected image of the virtual implants.
US10583300B2
Devices and methods are provided for a leadless implantable medical device (LIMD) comprising a housing. An electrode is disposed on the housing. An electronics circuit is disposed in the housing and is configured to sense cardiac signals, and/or generate and deliver pacing signals to the electrode. A transceiver circuit is disposed in the housing, and is configured to communicate wirelessly with an external device. A fixation antenna electrically separate from the electrode is disposed on a distal portion of the housing and is electrically coupled to the transceiver circuit, and configured to operate as an antenna for communication between the transceiver circuit and the external device.
US10583297B2
A stimulation protocol determination system includes an input module and a selector module. The input module is provided to receive an indication of an upper airway flow limitation via sensed respiratory effort information. The selection module is provided to automatically select, based on the indicated upper airway flow limitation, a stimulation protocol.
US10583296B2
An implantable pulse generator system includes a nerve stimulation unit providing vagal nerve stimulation (VNS) pulses; an autonomic tone sensor which determines the patient's autonomic status; and a control unit connected to the nerve stimulation unit and the autonomic tone sensor. The control unit controls the nerve stimulation unit to generate VNS with varying intensity, depending on the autonomic status (which is evaluated in a moving window). The control unit gradually increases VNS intensity when the autonomic status indicates a shift toward more sympathetic dominance, and it gradually decreases VNS intensity when the autonomic status indicates a shift toward more parasympathetic dominance, wherein the gradual increase and the gradual decrease of the VNS intensity follow two different paths.
US10583292B2
An implantable electronic neuromodulation system includes an implantable pulse generator comprising a controller and a memory. The memory is configured to store an emulated neurosensory signal representative of nerve traffic acquired from a patient equipped with an extra-aortic balloon pump counter-pulsation system or an intra-aortic balloon pump counter-pulsation system. A lead is coupled to the implantable pulse generator. At least one electrode is coupled to the lead. The at least one electrode is positionable in contact with or adjacent to at least one nerve that carries sensory information from baroreceptors. The controller is configured to stimulate the at least one nerve using the emulated neurosensory signal.
US10583291B2
An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body has a programmable signal generator that can generate the signals based on stored signal parameters without any intervention from a processor that controls the overall operation of the IPG. While the signal generator is generating the signals the processor can be in a standby mode to substantially save battery power.
US10583287B2
A method for aesthetic soft tissue treatment includes placing at least one applicator in contact with the patient's body. The applicator has at least one electrode. Electrotherapy and radio frequency therapy are provided to the soft tissue, optionally with overlay or sequentially. A handheld applicator may be used, with the applicator moving during the therapy, which may provide muscle stimulation in the patient, or provide an analgesic effect during the treatment. A spacing object may be positioned between the skin of the patient and the applicator.
US10583286B2
Aspects of the present disclosure are directed toward apparatuses, systems, and methods for delivering therapy to an adrenal gland of a patient. The apparatuses, systems, and methods may include a housing and a plurality of electrodes arranged with the housing. In addition, one or more of the plurality of electrodes may deliver stimulation energy to modulate L-dopa release.
US10583284B2
Methods for placing an electrical stimulation lead at a tibial nerve in a subject, and also for treating a tibial nerve-related condition or disease in the subject. The methods include depositing the electrical stimulation lead at a tibial nerve, activating the electrical stimulation lead to modulate the tibial nerve, and thereby treating the tibial nerve-related condition or disease in the subject.
US10583282B2
A nanodevice includes an array of metal nanorods formed on a substrate. An electropolymerized electrical conductor is formed over tops of a portion of the nanorods to form a reservoir between the electropolymerized conductor and the substrate. The electropolymerized conductor includes pores that open or close responsively to electrical signals applied to the nanorods. A cell loading region is disposed in proximity of the reservoir, and the cell loading region is configured to receive stem cells. A neurotrophic dispensing material is loaded in the reservoir to be dispersed in accordance with open pores to affect growth of the stem cells when in vivo.
US10583276B2
A robotic catheter system includes a drive mechanism comprising a drive which interacts with a catheter device to cause the catheter device to move along its axis. An encoder assembly detects the motion of the catheter device by a magnetic interaction with the catheter device.
US10583272B2
Catheter shaft handles and deflection actuators are disclosed. The actuators include at least one pull wire guide wall and a means for anchoring the proximal portion of a pull wire or of a fiber attached to a pull wire. Each actuator is pivotable relative to the catheter handle housing, and may comprise at least one boss for pivoting the actuator relative to the catheter handle housing. The actuators transfer rotational motion based upon user input on a boss into longitudinal motion of a pull wire. The actuators may include a tensioning mechanism comprising a tension adjustment pin and a pin block, wherein the tension adjustment pin is rotatably attached to the pin block to enable adjustment of tension in a pull wire (e.g., during assembly of the catheter handle).
US10583271B2
A catheter comprises a flexible polymer catheter body including a proximal shaft section and a distal working section, a wire support structure embedded within the distal working section of the catheter body, a proximal adapter mounted to the proximal shaft section of the catheter body, and a wire disposed within the catheter body. The wire has a proximal end and a distal end. The proximal end of the wire being operably connected to the proximal adapter, and the distal end of the wire is anchored to the wire support structure.
US10583265B2
Methods and system for concentrating oxygen include providing a portable apparatus having a plurality of sieve beds, each sieve bed in the plurality of sieve beds including a first end and a second end, a reservoir storing oxygen-enriched gas exiting from the second ends of the plurality of sieve beds, a compressor, an oxygen delivery valve communicating with the reservoir via a delivery line, a flow sensor associated with the delivery line, and control electronics adapted to control operation of the oxygen delivery valve; measuring, via the flow sensor, a flow of the oxygen-enriched gas through the sensor and outputting a signal indicative thereof; and controlling, using the control electronics, the opening and closing the oxygen delivery valve to deliver the oxygen-enriched gas from the reservoir to a user based on the signal.
US10583264B2
The present invention relates to the administration of warm humidified oxygen to patients suffering with breathing problems. The present invention more specifically relates to the high flow of warm humidified oxygen to patients suffering with breathing problems or suffering with asthma.
US10583260B2
An autoinjector includes a case, a syringe carrier slidably disposed within the case and adapted to hold a syringe including a stopper, a plunger slidably disposed within the syringe carrier and adapted to apply a force on the stopper, and a drive spring disposed within the plunger and biasing the plunger relative to the syringe carrier.
US10583258B2
The mechanism includes a body, a drive member movable in the body, a main spring that is loaded when a dose is set and is released for moving the drive member during a delivery of a dose, and a movable trigger inhibiting a movement of the drive member, a movement of the trigger releasing the main spring and the drive member. The trigger is moved from a start position to an end position relative to the body during a setting of a dose, the end position having a distance from the start position that increases as the dose set increases.
US10583255B2
The present disclosure relates to a medicament container assembly (11) for a medicament delivery device, comprising: an elongated body (3) configured to receive a medicament container (17) and provided with a radially flexible first gripper arm (3f) extending in the axial direction of the body (3) and an oppositely arranged radially flexible second gripper arm (3g) extending in the axial direction of the body (3), wherein the first gripper arm (3g) and the second gripper arm (3f) are configured to support a neck portion of a medicament container, and a clamp member (13) configured to be arranged radially outside of the first gripper arm (3f) and the second gripper arm (3g), to press the first gripper arm (3f) and the second gripper arm (3g) radially inwards, to prevent proximal displacement of a medicament container.
US10583243B2
An intravenous line organizing system to be attached to patients to organize one or several IV lines, preventing entanglement and contamination by dragging on the floor, while allowing patient mobility. The hypoallergenic device can be strapped with a band around a patient's limb or torso, or adhered to the skin anywhere on the body. Each clip element allows one IV line to float freely through it. Each clip element rotates 360° and can move horizontally within a channel in the system, or it can be pushed into a locked position, preventing rotation and horizontal movement.
US10583240B2
A package for a medical cannula with a hub, such as a pen needle, is disclosed. The package includes a cover for receiving a medical cannula and for engaging a hub of the medical cannula. The cover has open ends that are in communication through the cover. The packaging also includes a sterility barrier for the cover.
US10583237B2
A system and method for draining excessive fluid from a body cavity or space. The system comprises an implantable fluid penetrable chamber comprising a frame covered by a fluid permeable mesh configured to enable fluids to penetrate therethrough. The system further comprises a catheter connected at a first end to one of said chamber sides/walls or penetrates therethrough; and optionally further comprises a pump placed inside or outside of said chamber.
US10583232B2
A catheter pump assembly is provided that includes an elongate body, an elongate flexible shaft disposed in the elongate body, and an impeller coupled with the distal end of the elongate flexible shaft. The drive system includes a drive component, a motor and a tension member. The tension member is coupled with the motor and the drive component and to cause the drive component to rotate, and thereby to cause the impeller to rotate.
US10583228B2
Some embodiments of a multi-layered dressing system for sealed wound treatment include various components used for sealing, dressing, suctioning and irrigating that are coupled together as a single, composite unit.
US10583219B1
A multilayer bioabsorbable construct is provided that includes at least one top layer, at least one chorion membrane layer, at least one basement layer, and at least one support layer between the chorion membrane layer and basement layer. Various therapeutic uses of the multilayer bioabsorbable construct are also provided.
US10583213B2
Apparatuses are provided which include one or more germicidal sources, power circuitry coupled to the germicidal source/s, and a shield. The shield and/or at least one of the germicidal source/s are moveable within the apparatus and the apparatus is configured such that the shield and/or the germicidal source/s may be brought in and out of proximity with the other and upon doing so germicide projected from one or more of the germicidal source/s is either substantially contained in the apparatus or is projected exterior to the apparatus for different disinfection modes of the apparatus. The apparatuses include a processor and processor-executable program instructions for activating the power circuitry to operate the at least one germicidal source when the germicidal source is not encased within the apparatus and for activating the power circuitry to operate at least one germicidal source when the germicidal source/s are encased within the apparatus.
US10583212B2
A portable UV-C disinfection apparatus, method, and system for ultraviolet germicidal irradiation. UV-C emitters may be coupled to an array housing having a planar array surface in a vertical configuration. UV-C sensors are configured to measure the amount of UV-C light or near UV-C light from a target surface. A controller may be configured to engage with the UV-C sensors to determine the amount of UV-C radiation collected by the UV-C sensors. The controller includes instructions stored on a memory according to the amount of UV-C radiation collected corresponding to an effective kill-dose for surface disinfection. The improved apparatus, method, and system reduces exposure time by varying the intensity and wavelength of the UV-C administered, while concurrently reducing UV overexposure to surfaces by administering radiation through a rotational zonal application.
US10583207B2
The invention provides, inter alia, improved lipid formulations used to generate lipid-encapsulated gas microspheres, and methods of their use.
US10583204B2
The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the tranfected cell.
US10583198B2
The present disclosure provides methods for treatment of bladder cancer. The methods include administering an immunoconjugate to a subject in a dosing regimen that includes an induction phase with twice weekly followed by once weekly dosing, and optionally a maintenance phase. The immunoconjugates useful in the methods provided include immunoconjugates having a binding protein that specifically binds to Ep-CAM and a toxin molecule.
US10583195B2
Described is a conjugate of agent complex and at least one target-finding ligand, where the agent complex comprises an agent encapsulated by an encapsulation material and where the target-finding ligand is a prostacyclin analog, and the use of the conjugate.
US10583194B2
The present invention relates to the field of oligopeptide prodrugs that are intended for the treatment of cancer. The selectivity of these prodrugs requires the presence of an (oligo)peptidic moiety and/or a protective capping group to ensure the prodrug stability in blood. It further in particular relates to the exemplary oligopeptidic moiety ALGP and to prodrugs comprising it. In particular it also relates to the capping group phosphonoacetyl and to prodrugs comprising this capping group.
US10583188B2
Provided herein are chimeric influenza hemagglutinin (HA) polypeptides, compositions comprising the same, vaccines comprising the same, and methods of their use.
US10583183B2
This invention relates to methods for treating subjects with bladder cancer, such as urothelial carcinoma, based on mRNA expression levels of chemokines.
US10583182B2
The invention relates to cell stimulatory fusion proteins and DNA sequences, vectors comprising at least two agonists of TNF/TNFR super family, immunoglobulin super family, cytokine family proteins and optional antigen combination. Instructions for use of these proteins and DNA constructs as immune adjuvants and vaccines for treatment of various chronic diseases such as viral infection are also provided. Additionally, the use of these protein and DNA constructs as immune suppressant for treatment of various chronic diseases, such as autoimmunity and organ transplant rejection, is also illustrated.
US10583179B2
The present subject matter is directed to a method of manufacturing and purifying an intraveneous injection of prothrombin complex concentration (PCC) from plasma Fraction III, comprising reconstituting a Fraction III paste in a buffer to create a Fraction III suspension; adjusting pH and temperature of the Fraction III suspension; performing PEG precipitation; centrifuging the Fraction III suspension and collecting a supernatant; filtering the supernatant; performing solvent detergent virus inactivation of the supernatant; undergoing weak anion exchange chromatography of the supernatant; twice washing and eluting two to three times; ultra-filtering the supernatant; adjusting pH of the supernatant; adjusting activity of a human factor IX of the supernatant; performing aseptic filtration and nano filtration for virus removal; and filling and lyophilizing to obtain the intraveneous injection of PCC.
US10583173B2
Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b (Nppb) blocking agent to a mammal in an amount effective to treat or prevent pruritis in the mammal. An in vitro method of identifying a compound that inhibits Nppb activity is also disclosed.
US10583171B2
The present invention relates to an N-Methyl-D-aspartate (NMDA) receptor antagonist, for use in the treatment of diseases associated with angiogenesis such as tumor angiogenesis, ocular neovascular disease, Age-related macular degeneration (AMD).
US10583163B2
A pharmaceutical composition and a food composition for preventing, alleviating or treating precocious puberty, which contain, as an active ingredient, a hot-water extract of Coicis Semen and Artemisia capillaris, which inhibits early ovary growth and the production of follicle-stimulating hormone. The composition contains a hot-water extract of Coicis Semen and Artemisia capillaris, which can inhibit early ovary growth and follicle stimulating hormone production, thereby preventing, alleviating or treating precocious puberty.
US10583149B2
The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
US10583148B2
Disclosed are methods for identifying patients at increased risk of developing disseminated staphylococcal infection, which includes the steps of determining that the patient has a mutation in one or more genes selected from a MPDZ network gene, a CGNL1 network gene, a PRKRIR network gene, a MED26 network gene, a tight junction protein gene, or an immune modulator gene; and treating the patient for disseminated staphylococcal infection. Also disclosed are solid substrates and/or assays useful for carrying out the disclosed methods.
US10583147B2
This disclosure relates to a composition that includes an active agent and a porous cyclodextrin-based metal organic framework (CD-MOF). The CD-MOF includes at least a metal cation and a plurality of cyclodextrin molecules. The composition includes from about 0.05 mg to about 0.5 mg of the active agent per 1 mg of the CD-MOF. Methods of preparing and using the compositions are also disclosed.
US10583129B2
This invention is directed to prostaglandin E2 receptor 4 (EP4) antagonists useful in the treatment of nonalcoholic steatohepatitis (NASH)-associated liver cancer in a human or animal. The method comprises administering one or more of Compound A, Compound B or Compound C, or pharmaceutically acceptable salts thereof, as the EP4 antagonist(s). The method may include a pharmaceutical composition comprising the EP4 antagonist, and may include one or more other active agents and/or therapies.
US10583127B2
The present invention relates to the tromethamine salt of (1R,3S)-3-(5-cyano-4-phenyl-1,3-thiazol-2-ylcarbamoyl)cyclopentane carboxylic acid, a process for obtaining said salt, combination products and pharmaceutical compositions comprising said salts and their medical uses, in particular for the treatment or prevention of diseases known to ameliorate by A1 adenosine receptor antagonism.
US10583115B2
The present disclosure relates to modulators of 14-3-3 functionality and their use in methods and compositions for preventing and/or treating various diseases, conditions and states, such as cancer and healing of wounds. Certain embodiments of the present disclosure provide a method of preventing and/or treating a disease, condition or state in a subject associated with altered 14-3-3 protein functionality and/or which would benefit from altering 14-3-3 functionality, the method comprising administering to the subject an effective amount of an agent which inhibits dimerization of the 14-3-3 protein, thereby preventing and/or treating the disease, condition or state in the subject.
US10583102B2
The present invention relates to the field of Wilson Disease. More specifically, the present invention provides methods and compositions useful for treating Wilson Disease by targeting liver nuclear receptors. In a specific embodiment, a method for treating Wilson Disease in a subject comprises the step of administering to the subject an effective amount of a liver X receptor (LXR) agonist.
US10583101B2
The present invention relates to a pharmaceutical lipid composition comprising nitrosoureas and process for its preparation. In particular, the compositions of present invention are useful in the treatment of brain cancers having improved physicochemical and pharmacokinetic characteristics.
US10583100B2
The present invention relates to TRPV1 selective agonist compositions including a capsaicinoid, a surfactant and an extended release agent, and to methods of manufacture and methods of providing pain relief as well as treating a variety of disorders with such compositions.
US10583099B2
The present invention is directed to 2H isotope enhanced ambroxol (“isotope enhanced ambroxol”) and its use in the treatment of autophagy infections, especially mycobacterial and other infections, disease states and/or conditions of the lung, such as tuberculosis, especially including drug resistant and multiple drug resistant tuberculosis. Pharmaceutical compositions comprising isotope enhanced ambroxol, alone or in combination with an additional bioactive agent, especially rifamycin antibiotics, including an additional autophagy modulator (an agent which is active to promote or inhibit autophagy) are also disclosed. These compositions are useful against an autophagy mediated disease state and/or condition), especially an autophagy mediated disease state and/or condition which occurs in the lungs.
US10583091B2
This invention relates to amphiphile-polymer particles comprising obtaining a first solution comprising a water-insoluble polymer, a payload and a first amphiphile in a water-miscible solvent; mixing the first solution with an aqueous second solution to form an aqueous composition comprising a particle comprising a water-insoluble polymeric core comprising the water-insoluble polymer; the payload; and the first amphiphile.
US10583090B2
The present invention provided for a novel process of forming silk fibroin gels, and controlling the rate of β-sheet formation and resulting hydrogelation kinetics, by vortex treatment of silk fibroin solution. In addition, the vortex treatment of the present invention provides a silk fibroin gel that may be reversibly shear-thinned, enabling the use of these approach for precise control of silk self-assembly, both spatially and temporally. Active agents, including biological materials, viable cells or therapeutic agents, can be encapsulated in the hydrogels formed from the processes, and be used as delivery vehicles. Hence, the present invention provide for methods for silk fibroin gelation that are useful for biotechnological applications such as encapsulation and delivery of active agents, cells, and bioactive molecules.
US10583088B2
Disclosed herein are compositions comprising a drug such as a triptan (e.g. rizatriptan) and/or an NSAID (e.g. meloxicam) in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability, solubility, or pharmacokinetics of the drug for the treatment of conditions such as pain.
US10583073B2
A surfactant composition comprising a sugar-based surfactant comprising a C8-C16 alkyl glucoside, a C8-C16 alkyl polyglucoside, or a combination of a C8-C16 alkyl glucoside and a C8-C16 alkyl polyglucoside; a C8-C18 amphodiacetate; a C8-C16 acyl sarcosinate, a C8-C16 acyl glutamate, a C8-C16 acyl glycinate, or a combination thereof; and optionally a C8-C14 acyl lactylate, wherein the composition is free of sulfated anionic surfactants.
US10583069B2
The present invention relates to a method for treating the kidney with extracorporeal shockwaves in a noninvasive manner and in particular, to such a method for the treatment of the nephrons about the glomerulus.
US10583068B2
The apparatus comprises: an adjustable lens module, configured to image an object viewed by eyes an eye; an analysis and processing module, configured to determine whether time during which a change amount of a distance between a gaze point of the eye and the eye is within a set range exceeds a set threshold, and when the time exceeds the set threshold, send adjustment triggering information to a parameter generating module; the parameter generating module, configured to generate adjustment information of an imaging parameter of the adjustable lens module according to the adjustment triggering information; and a lens adjustment module, configured to adjust the imaging parameter of the adjustable lens module according to the adjustment information of the imaging parameter. A probability of occurrence or deterioration of a sight problem, e.g., nearsightedness, due to improper use of eyes is reduced without affecting work, study, entertainment, etc. being currently performed by a user.
US10583067B2
User devices, methods, and computer-readable media are described for providing source-of-sound based navigation to a visually-impaired user. A sound detected at a user device of a visually-impaired user is categorized and an approximate location of a source of the sound is determined. A contextual analysis is performed based on the determined sound category such that the results of the contextual analysis indicate whether the visually-impaired user should be directed towards or away from the location of the sound source. An evacuation path is determined in those scenarios in which the user should be directed away from the detected sound and a tactile representation of the evacuation path is generated on a display of the visually-impaired user's device. A navigation path is determined in those scenarios in which the user should be directed towards the detected sound and a corresponding tactile representation thereof is generated.
US10583062B2
A joint assembly may include a profile ring including a cam profile, a rotor configured to rotate relative to the profile ring, and an elastic body configured to connect to the rotor, and to store an elastic potential energy corresponding to the cam profile in response to the rotor rotating relative to the profile ring.
US10583059B2
An incubator system for a neonate includes a humidifier containing a water reservoir and a water age module that detects a cleaning event of the water reservoir, determines a water age based on a duration since the cleaning event, and compares the water age to a preset expiration time. Once the water age exceeds the present expiration time an expiration alert is generated.
US10583048B1
Disclosed is a fluid detection device including a fluid sensor positioned near a patient's body and providing a signal whether the sensor detects fluid from the patient's body; a casing surrounding the alarm and allowing the signal to be sensed by the patient; an alarm coupled to the fluid sensor, the alarm including one or more of: an audible signal sensible by the patient, a haptic signal sensible by the patient, a visible signal sensible by the patient through the casing; a casing surrounding the alarm and allowing the signal to be sensed by the patient; and a fastener coupled to the casing, adjustable to attach and remove from one or more of: the patient's body, the patient's clothing. The casing, when closed, may couple a power source to the alarm. Also included may be a human interface and other features. Also disclosed is a fluid detection method.
US10583039B2
Improved devices, systems, and methods for planning cataract surgery on an eye of a patient incorporate results of prior corrective surgeries into a planned cataract surgery of a particular patient by driving an effective surgery vector function based on data from the prior corrective surgeries. The exemplary effective surgery vector employs an influence matrix which may allow improved refractive corrections to be generated so as to increase the overall efficacy of a cataract surgery by specifying one or more parameters of an intraocular lens (IOL) to be implanted during the cataract surgery.
US10583038B2
Fluid delivery devices and methods are described where the device may comprise a piezoelectric actuator having a piezoelectric chip that is operatively coupled to a drug package under a preloading force. The actuator is configured to generate an acoustic pressure within the drug package to dispense droplets or a continuous stream of an agent from an aperture, e.g., to the corneal surface of the eye. The piezoelectric actuator can be coupled or decoupled from the drug package via a coupling mechanism which enables the quick release and consistent securement of the drug package to the actuator and housing.
US10583028B2
Methods and apparatuses for aligning a person's center of gravity over the base of support using a weighted garment or orthotic are herein provided. These methods and apparatuses are particularly suited to individuals suffering from various balance or neurological disorders. The methods described herein involve the use of body positioning and perturbation techniques. These methods may be manual, computer assisted, or some combination thereof. In some variations, video recording equipment or other electronic equipment is used. The apparatuses of the present invention comprise a variety of weighted garments or orthotics. These garments or orthotics may take on any number of configurations. In some variations, the weighted garment or orthotic is a vest, in other variations, the weighted garment or orthotic is a brassiere, corset, shoulder pad, undergarment, belt, seating device to be used in combination with a wheelchair, tee shirt, body suit, or combinations thereof.
US10583026B2
The invention refers to a body fitting element with negative pressure controlled stiffness comprised of a gas tight envelope (1), a plurality of layers fitted in the envelope (3) and a valve (2) adapted to evacuate the interior of the envelope, characterized in that the layers comprise a core (4a) made of a material with a high Young's modulus and flexibility and a first cover layer at both sides of the core made of a material with high friction coefficient (4b). Orthoses and protective equipments fabricated with the fitting element can be shaped and fitted to the body in an optimal manner.
US10583020B2
Delivery system embodiments for treatment of a vascular defect of a patient's vasculature that may include an endoluminal prosthesis loaded on a delivery catheter. In some cases, an inflatable balloon used to facilitate deployment of the endoluminal prosthesis may be disposed within an inner lumen of a tubular graft portion of the endoluminal prosthesis.
US10583017B2
A prosthetic hand structure including at least one mechanical finger having a metacarpal support and a proximal stiff link connected to the metacarpal support by a proximal cylindrical joint. The mechanical finger includes a transmission member connected to the proximal stiff link. The transmission member includes a worm screw integral to the proximal stiff link. The transmission member includes a flexible rack having a first end portion, pivotally connected to the metacarpal support, and a second end portion arranged to engage with the threaded profile of the worm screw at an engagement zone of the flexible rack. The structure also includes an actuator mounted to the mechanical finger and to actuate the worm screw, causing it to rotate about its rotation axis, in such a way that, when the actuator moves the worm screw, the mechanical finger extends or flexes.
US10583013B2
An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon.In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.
US10583006B2
A valvuloplasty device comprises an expandable anchor and an expansion member mounted about an outer surface of the expandable anchor. The expansion member is either an annular balloon or a sleeve. The valvuloplasty device can be used for valvuloplasty and for valve implantation.
US10583003B2
The present relates to a method of making a prosthetic valve that can take a first form wherein the valve is open and a second form wherein the valve is closed, the valve comprising a leaflet, a supporting element, and a stent to which the leaflet and supporting element are attached, the leaflet having a free margin that can move between a first position wherein the valve takes the first form and a second position wherein the valve takes the second form, the method comprising:—providing a woven textile structure,—forming the leaflet and the supporting element from this textile structure, such that a selvedge of the textile structure forms the free margin of the leaflet, and—forming the valve therewith, wherein the textile structure has a single layer thickness of between 40 to 150 μm and comprises yarn comprising polymeric filaments, the yarn having a linear density of less than 120 dtex and an elongation at break of 10% or less, and wherein the leaflet is attached to the stent by making stitches through at least 2 layers of the woven textile structure to form a commissure. The woven fabric used method is thin and flexible, and allows stitching through multiple layers to result in durable performance of both leaflets and commissures in actual use. The invention also relates to a prosthetic valve as obtainable by said method.
US10583002B2
A prosthetic valve for implanting in a patient's native valve has a self-expanding frame that comprises a first end, a second end opposite the first end, an anterior portion, and a posterior portion. The self-expanding frame has an expanded configuration adapted to engage tissue at a treatment site, and a collapsed configuration adapted to be delivered to the treatment site. The expandable frame also comprises a self-expanding atrial skirt near the second end, a self-expanding ventricular skirt near the first end, a self-expanding annular region disposed between first and second ends, a first self-expanding anterior tab disposed on the anterior portion, and a self-expanding foot coupled to the posterior portion and extending radially outward. The foot has an outer surface for engaging the tissue thereby facilitating anchoring of the prosthetic valve and minimizing or preventing rotation of the prosthetic valve.
US10582999B2
Various joint replacements are disclosed herein, as are methods of use thereof. The joint replacements can have a flexible band or multiple flexible bands that can link together a first part of the joint replacement and a second part of the joint replacement. The flexible band or bands can be tensioned to establish proper tension in the patient's joint. In certain circumstances, the joint replacement can be a shoulder joint replacement.
US10582994B2
A medical implant packaging assembly having an outer tray, an inner tray and a retainer The implant may include a tissue graft. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, thereby avoiding need for rehydrating steps that are required for dehydrated or cryopreserved implants. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.
US10582990B2
A head module capable of reciprocal rotation for an electric cleaning apparatus comprises cleaning elements, a housing and a driven rod disposed in a hollow inner cavity of the housing, wherein the rod is provided with a hollow cavity body for accommodating a drive shaft; at least one gap is provided in a region surrounding the hollow cavity body; at least one inner side notch is distributed on a side wall of the inner cavity, for accommodating a protrusion; the rod further comprises a partially cylindrical or conical cavity body region. When the drive shaft is not yet inserted into the rod, there is a gap between the notch and the protrusion in a direction perpendicular to the rotation axis (L1) of the drive shaft. The length of the gap is greater than or equal to the amount of single-side interference between the rod and the drive shaft.
US10582984B2
A method for attaching a test fixture to a surgical instrument comprising removing a valve member from a valve chamber of a surgical instrument and removing another valve member from another valve chamber of the surgical instrument. The method further comprises inserting a valve member analogue extending from a frame of a test figure into the valve chamber, wherein the valve member analogue comprises a first seal and a second seal, and wherein the first and second seals are configured to seal at least a portion of the valve chamber of the surgical instrument. The method further comprises inserting another valve member analogue extending from the frame, wherein the valve member analogue and the another valve member analogue define a longitudinal axis extending substantially therebetween. The method further comprises securing the test fixture to the surgical instrument by moving the housing substantially perpendicular to the longitudinal axis into a locked position.
US10582973B2
The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures.
US10582972B2
An intraoral 3D scanner includes a probe light source configured to generate a probe light such that the probe light is transmitted towards the dental situation; a camera including an array of sensor elements, the camera being arranged such that the probe light from the dental situation is transmitted to the array of sensor elements, wherein the camera is configured to create images of the dental situation from which a point cloud is generated, and a guiding system configured to guide relative movement of the intraoral 3D scanner towards the dental situation, wherein the camera is part of the guiding system, the camera is configured to record images from which a relative position of the intraoral 3D scanner and the dental situation is determined, such that based on the relative position, the guiding system is configured to provide a positioning signal in the form of a positioning color code.
US10582959B2
A screw (1), in particular a bone screw, comprising a head (16), a shaft (2) and a point (15). The screw (1) has a recess (4) with a contour (5) on a head side (3), The screw (1) is provided with an insertion post (8) in the recess (4), which insertion post is connected to the screw (1) via a predetermined breaking point (7). After breaking the predetermined breaking point and separation of the insertion post (6) from the screw (12), a counter-contour (13) of a tool (12) can be brought into operative connection with the contour (5) of the recess (4). The predetermined breaking point (7) is arranged within the recess (4) such that, after removal of the insertion post (6), a transmission of torque is possible between the tool (12) and the screw (1) via the contour (5) and the counter-contour (13).
US10582955B2
Methods of installing bone plates on adjacent vertebrae are provided.
US10582951B2
Everting balloon systems and methods for using the same are disclosed herein. The systems can be configured to access and dilate body lumen and cavities. For example, the systems can be used to dilate the cervix and access the uterine cavity. The systems can also be used to occlude the cervix. The systems can also be used to occlude the urethra.
US10582950B2
A method is provided for puncturing a fossa ovalis of a heart, the method including inserting a catheter into a right atrium of the heart, and advancing a distal portion of the catheter toward an interatrial septum of the heart. A flexible longitudinal member is slid through openings disposed at the distal portion of the catheter, such that the flexible longitudinal member is made to loop around a portion of an inside perimeter of the fossa ovalis. While the flexible longitudinal member is looped around the portion of the inside perimeter of the fossa ovalis, a hole is punctured in the fossa ovalis at a puncturing point.
US10582947B2
The present invention provides a follicle transfer and transplantation method based on FUE, which provides a follicle extraction punch for transferring and transplanting a follicular unit of a scalp and loads a follicular unit, extracted by the follicle extraction punch, to the follicle extraction punch itself or transfers the extracted follicular unit to a separate needle, thereby enabling a hair transplantation operation to be relatively quickly and accurately performed.
US10582942B2
Methods and devices for blunt dissection include a drive mechanism comprising an elongate rotary drive train having a first proximal end connected to a mounting base for attaching to a handle or a surgical robot and a second distal end. The drive mechanism comprises a differential dissecting member (DDM) configured to be rotatably attached to the second distal end. The drive mechanism further comprises a mechanism configured to mechanically rotate the DDM about a substantially transverse axis of member rotational oscillation, thereby causing at least one tissue engaging surface to move in at least one direction against complex tissue and selectively engage the complex tissue such that when the DDM is pressed into the complex tissue, the at least one tissue engaging surface moves across the complex tissue and disrupts at least one soft tissue in the complex tissue, but does not disrupt firm tissue in the complex tissue.
US10582938B2
A medical device may include a plurality of branch members having moveable distal portions. The medical device also may include a first moveable member movably connected to the distal portion of one of the branch members at a first location along the branch member. The first moveable member may have first and second proximal portions extending from the first location and disposed within one or more lumens of one or more of the other branch members. The moveable distal portions of the plurality of branch members and the first moveable member may form a first snare movable between a collapsed configuration and an expanded configuration.
US10582924B2
A method for performing thorascopic repair of heart valves includes inserting an instrument through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw a suture therethrough.
US10582919B2
Various devices, systems and methods for knotless anchoring of sutures to repair bodily tissue are disclosed. These devices allow sutures to be anchored to bone or other tissues, and more specifically provide a suture anchor which eliminates the need for the operator to knot the suture to secure the suture under tension. Thus, damaged tissue may be re-attached to a substrate tissue. The anchors have a minimum of moving parts and find particular utility in hip and shoulder arthroscopy, e.g. labral reattachment, rotator cuff repair, and similar procedures.
US10582893B2
An oximeter includes a main body defining an opening and a finger clamping device arranged in the opening. The finger clamping device includes a shell, an upper clamping member, and a lower clamping member. The shell includes an inner wall carrying a sliding rail. The upper clamping member is arranged in the shell and defines a spindle. A portion of the spindle is received in the sliding rail and can slide along the sliding rail. The lower clamping member faces the upper clamping member and is coupled to the upper clamping member by a torsion spring. A finger being inserted between the upper clamping member and the lower clamping member causes the torsion spring to stretch, the finger is thus clamped by the upper clamping member and the lower clamping member with an elastic restoring force.
US10582892B2
Disclosed is a vascular image positioning system, including an image enhancing device (1) and an image projection device (2) used cooperatively with the vascular image enhancing device (1). The transmission light emitted by the enhancing device (1) passed through the sites of the human body surface to be tested, is received by the image projection device (2), and after image processing, forms in situ images at sites on the surface of the skin of the human body to be tested. The enhancing device (1) comprises a light emitting unit (101) and a drive unit (102) driving the light emitting unit (101) to emit light. The vascular image positioning system provides the function of using a transmission light source to achieve in situ imaging of the blood vessels at the sites to be tested; secondly, it also provides a mode for combining a transmission light source with a reflection light source, thereby strengthening the function of in situ imaging and widening the application range.
US10582889B2
An apparatus (100) for assessing the condition of the bone tissue in a patient's bone region (21). The apparatus includes an ultrasound device (11) that transmits/receives ultrasounds along a plurality of ultrasound propagation lines (15i) for the bone region (21), and for receiving in response from the bone region (21) a plurality of raw reflected ultrasound signals (36,38); a device for generating an ultrasound signal, a sonographic image formation device for forming a sonographic image (29) of the bone region (21), starting from the raw reflected ultrasound signals (36,38); a device for extracting at least one frequency spectrum (43.sub.i,44.sub.i,47,48) starting from at least one part of said plurality of raw reflected ultrasound signals (36,38) coming from corresponding points (34) of the bone region (21), each having a plurality of harmonic components.
US10582885B2
The present invention relates to a device and method for noninvasively determining the hematocrit value of a subject. The device comprises a light source (22, 23) for emitting light onto a skin area of the subject, said light comprising first light at a first wavelength in a first wavelength range between 500 and 1000 nm and second light at a second wavelength in a second wavelength range between 1000 and 2000 nm, a reflection detector (24) for detecting light reflected from said skin area of the subject in response to light illumination by said light source, a transmission detector (25) for detecting light transmitted through said skin area of the subject in response to light illumination by said light source, a processing unit (31) for deriving plethysmography, PPG, signals for said first and second wavelengths from the light detected by said reflection detector (24) and said transmission detector (25), and an analysis unit (32) for determining the hematocrit value of the subject from said PPG signals.
US10582883B2
Systems and methods are provided for determining an acceleration at a location of interest within one of a user's head and neck. At least one of linear acceleration data, angular acceleration data, angular velocity data, and orientation data is produced using at least one sensing device substantially rigidly attached to an ambient-accessible surface of the user's head. The location of interest is represented relative to a position of the at least one sensing device as a time-varying function. An acceleration at the location of interest is calculated as a function of the data produced at the sensing device and the time-varying function representing the location of interest. The calculated acceleration at the location of interest is provided to at least one of the user and an observer in a human-perceptible form.
US10582878B2
Systems and methods of are disclosed for providing visual feedback to a subject during magnetic resonance imaging, where the visual feedback is associated with input provided by the subject to a magnetic resonance compatible touch panel. A video camera is employed to record video images of the interaction between the subject and the touch panel, and the video images are processed to generate a real-time video signal including a rendering of the input provided to the touch panel and the interaction between the subject's hands and the touch panel. The real-time video signal is provided to the subject as visual feedback, and is displayed within a time duration that is sufficiently fast to avoid the detection of the visual feedback as an error signal with the subject's brain in relation to the sense of proprioception. A measurement of the force applied to the touch panel by the subject may be recorded and employed when rendering the real-time video. The systems and methods may be employed for a wide range of diagnostic and therapeutic procedures involving magnetic resonance imaging.
US10582863B2
An external stylus provides an impulse to correct mal-alignments of the Atlas (C1). The placement and direction of the impulse is guided by the analysis of a plurality precisely placed or acquired tomographic images, preferably MRI images.
US10582854B2
A method and system for determining thermistor resistance have been disclosed. The method comprises providing a temperature sensor network within a wireless sensor device, wherein the temperature sensor network includes a driver device and a receiver device, coupling the driver device to the receiver device using a dual bond wire system, determining at least one output voltage using at least one input current flowing through the dual bond wire system, and determining the thermistor resistance using the at least one output voltage. The system comprises a wireless sensor device including a temperature sensor network that comprises driver and receiver devices, and a dual bond wire system that couples the driver device to the receiver device, wherein at least one output voltage is determined using at least one input current flowing through the dual bond wire system, further wherein the thermistor resistance is determined using the at least one output voltage.
US10582853B2
Fundus imaging includes selective illumination and exposure of an image sensor array. Fundus imaging systems and methods disclosed herein are wide field of view imaging typically conducted under non-mydriatic conditions. At a first time, an illumination unit illuminates a first portion of an eye fundus. At a second time, the illumination unit illuminates a second portion of the eye fundus. One or more fundus images are captured during illumination.
US10582843B2
An illumination system for a surgical device is provided. The illumination system includes a tubular body made of a light permeable material and having at least one lumen extending between a distal end and a proximal end. The illumination system further includes a light source. At least one light diffusing optical fiber is disposed in the at least one lumen, the at least one light diffusing optical fiber having a core, primary cladding, and a plurality of nano-sized structures, the optical fiber further including an outer surface, and an end optically coupled to the light source. The fiber is configured to scatter guided light via the nano-sized structures away from the core and through the outer surface, to form a light-source fiber portion having a length that emits substantially uniform radiation over its length.
US10582841B2
A dark field endoscopic microscope includes an illumination system, an objective lens unit arranged in an optical path of the illumination system, an optical fiber bundle optically coupled to the objective lens unit, and an observation system arranged in an optical return path from the optical fiber bundle. The illumination system provides oblique off-axial illumination while axial rays are at least attenuated.
US10582832B2
An endoscopic system including an endoscope having saved information therein related to the endoscope, a light source console for providing light to the endoscope, and a light cable connected between the endoscope and the light source console. The light cable is configured to communicate the light from the light source console to the endoscope. The information related to the endoscope is relayed from the endoscope to the light source console through the light cable for altering functions of at least one of the light source console and an auxiliary device.
US10582825B2
An apparatus is provided which is capable of cleaning soiled concrete or other hard surfaces using significantly less water and detergent than typical pressure washers. A dual brush mode allows for more surface treatment. A safety electrical system allows the system to be used safely outdoors. The highly maneuverable maintainer utilizes industry standard components from floor maintenance equipment integrated with a horizontally stable wheeled platform, as well as, an adjustable and wear-compensating suspension system that can accommodate a variety of surfaces. The result is a low noise, low carbon footprint, low resource apparatus that moves easily in any direction while providing direct rotary brush scrubbing to clean soiled concrete or other hard surfaces.
US10582814B2
A dispenser for interfolded napkins includes a container having a supporting surface for supporting a stack of interfolded napkins. The supporting surface extends in a horizontal plane, and is surrounded by side walls extending in a vertical direction perpendicular to the supporting surface. The side walls define a dispensing opening opposite the supporting surface. At least one tab is arranged in the container for retaining the stack of napkins during withdrawal of a napkin from the stack. The tab is pivotably arranged in relation to the container between a holding position, in which the tab extends horizontally over at least a portion of the dispensing opening, and a refill position, in which the tab is directed away from the dispensing opening. The tab pivots about a living hinge. One or more stop surfaces limit an extent to which the tab is able to turn about the living hinge toward the dispensing mouth.
US10582813B2
A device that provides temporary bathroom and toilet area illumination is provided. The device is best characterized as a toilet tissue spindle nightlight, containing various electronic subassemblies that operate together as a bathroom night lighting system. The spindle is capable of sensing movement, or vibrations, when a user accesses the roll of toilet tissue being held by the spindle. When movement is detected, the spindle automatically activates an integrated light to provide temporary and effective bathroom area illumination.
US10582811B2
A container used to hold and transport items that get wet during use such as bar soap, razors, toothbrushes and clothing. Ducts in the container allow drier air from outside the container to mix with moist air inside the container to aid in the drying process. The ducts protrude into the container such that the openings in the ducts are presented above the level of any liquid dripping from the wet items regardless of the container's orientation. Thus, retaining the relatively small amount of liquid droplets and providing ventilation for drying. An embodiment can also arrange the position of the ducts to aid in the retention of the contained items to limit the movement of contents during transport.
US10582795B1
A portable secure mailbox system providing a mail container unit having a container-unit protrusion, a container-unit door, and a container-unit partition, a base anchor unit allowing filling with anchoring material such as water or sand, and having a base-unit recess, base-unit wheels, a base-unit removable plug, and a base-unit foot, at least one bolt and nut to secure the mail container unit to the base anchor unit, a powered sensor-transmitter unit to detect activity and transmit notifications, an optional solar array to recharge the powered sensor-transmitter unit, and an optional ornamental casing. The portable secure mailbox system provides a mailbox and support base that can be easily transported and put in place, when empty, and, after the base anchor unit is filled with anchoring material such as water or sand, and the mail container unit is mounted upon the base anchor unit, provides a stable secure mailbox that can detect activity and transmit notifications. The portable secure mailbox system also provides a mailbox and support base that yield somewhat if struck by a vehicle, such that the mailbox remains functional and damage to the vehicle and driver is reduced.
US10582790B2
A bottle storage includes a container that contains a bottle; a cooling-warming apparatus provided to surround a position where the bottle is contained; and an image capturer that captures an image of the bottle contained in the container. The cooling-warming apparatus has a gap at least at a portion of the cooling-warming apparatus corresponding to at least a part of an image capturing region of the image capturer.
US10582787B2
A paper-based container lid comprises a top wall, a side wall connecting to the top wall, and a sealing channel formed on the side wall for sealingly engaging a rim of the container and securing the lid to the container, wherein the top wall and the side wall are preferably formed from separate blanks.
US10582784B2
A cushion assembly includes a neck pillow and a side pillow. The neck pillow includes a supporting body with a supporting surface which, when viewed from a left side or a right side of the neck pillow, comprises a convex-shaped cervical support area and a concave-shaped head support area, a rigid portion with a rigid portion hardness, and a soft portion arranged on an upper side of the rigid portion. The soft portion has a soft portion hardness which is less than the rigid portion hardness. The supporting body is configured so that each of a head and a cervical spine of a person using the pillow rests on the soft portion. The side pillow includes a support body with a supporting surface which has a rising forearm support area, a convex-shaped wrist support area, a concave-shaped finger support area, and a convex-shaped grab area.
US10582780B2
A mattress wherein a plurality of independent yarn based fire barrier fabrics encases a plurality of distinct and unattached interior core structures. The plurality of interior core structures include at least a detached and internally flippable upper comfort layer assembly with a plurality of non-homogeneous foams or filling materials encased in a yarn-based fire barrier fabric and a lower, interiorly disposed support core structure with resilient filling materials encased in a yarn-based fire barrier fabric and a fabric cover. The detachable and internally flippable upper comfort layer assembly may be contained in a user accessible compartment that is fashioned into an outer cover assembly.
US10582779B2
Modular mattress systems and methods are described. For example, a modular mattress can include a fabric cover configured to surround at least two foam layers. The fabric cover can include an opening to allow access to an interior region of the fabric cover. The mattress can include a first foam layer positioned within the interior region of the fabric cover, and an encasement layer positioned below the first foam layer. The encasement layer can include a recess configured to receive one or more modular support sections. The mattress can also include a plurality of modular support components received within the recess of the encasement.
US10582770B2
A bathroom base cabinet may include a blower device and a footstool for a drying function and a foot holding function. The bathroom base cabinet may perform a function of drying a bathroom floor by blowing wind in a direction of a floor surface of the bathroom, and a function of drying the body of a user by blowing wind in a direction of an upper surface of the footstool.
US10582763B1
The hair brush includes a removable handle that provides a secret compartment therein. The hair brush is also further defined with a brush head that is of hollowed construction, and includes componentry to provide accelerated air or a mist. The brush head interfaces with the handle to enable the device to be handheld. The brush head is further defined with a rear surface on which a mirrored surface is provided. A plurality of lights encircles the mirrored surface so as to illuminate an end user when viewing the mirrored surface. The brush head is further defined with a front surface from which a plurality of brush bristles extend. The plurality of brush bristles is adapted to interface with hair.
US10582761B2
An oral care implement having movable and fixed tooth cleaning elements. The oral care implement may include a handle and a head coupled to the handle. The head may include a base that is coupled to the handle and a resilient bridge coupled to the base. The resilient bridge may be flexible between a normal state in which a portion of the resilient bridge is spaced from the base by a gap and a flexed state in which a portion of the resilient bridge is moved toward the base. Tooth cleaning elements may be coupled to the resilient bridge. Furthermore, the resilient bridge may include one or more apertures through which tooth cleaning elements that are fixed to the base may extend.
US10582759B1
A primary sheet has an upper section and a lower section and a fold line there between. The lower section has a lower periphery featuring a horizontal upper edge, a horizontal lower edge, a forward edge, and a rearward edge whereby the lower section creates the peripheral appearance of a holster. A large pocket is formed of an inner secondary sheet and an outer secondary sheet. The secondary sheets have a secondary periphery the same as the periphery of the lower section of the primary sheet. A small, pocket is formed of a tertiary sheet peripherally stitched to the outer secondary sheet of the large pocket along the lower edge, the forward edge, and the rearward edge. The small pocket has a free upper edge spaced below the fold line.
US10582753B2
A cosmetic applicator includes a container for containing a product to be dispensed and a tip threadably retained on the container. The tip includes an application surface including a thermal member and an opening in the application surface in fluid communication with the container through which the product is dispensed. The tip application surface is configured to contact a user's skin to apply the product to be dispensed and an opening in the application surface through which the product to be dispensed is dispensed from the reservoir. At least one of the dispensing tip or the cap includes a thermal member.
US10582751B2
A support for a hair care appliance, the support including a stand portion that includes an aperture that extends through the stand portion and a collar that extends around the aperture, wherein the collar is adapted to retain an appliance with respect to the aperture so that fluid exiting the appliance is in fluid communication with the aperture of stand portion. The stand portion may include a first side and a second side wherein the first side is adapted to receive and retain the appliance. The collar may at least partially define an inner periphery of the aperture. The collar may include a first ring which at least partially defines the inner periphery of the aperture. The collar may include a second ring disposed radially inwards of the first ring.
US10582743B2
An active interlocking fastener system is adapted to control an interlock in response to an external stimulus. The interlocking fastener system includes a first element including a plurality of first interlocking fasteners. The interlocking fastener system also includes a second element including a plurality of second interlocking fasteners configured to couple to the first plurality of interlocking fasteners. The plurality of first interlocking fasteners or the plurality of second interlocking fasteners includes a reactive material configured to vary a mechanical engagement between the plurality of first interlocking fasteners and the plurality of second interlocking fasteners as a function of the external stimulus.
US10582734B1
A magnetic zipper includes a pair of mating strands each having a plurality of spaced teeth formed on an inner edge thereof with mating notches formed therebetween. Positioned within each of the notches on both strands is a magnet having a given polarity. Attached to each tooth on both strands is a magnet having a polarity opposite that of the given polarity. The size or geometric configuration of the teeth and notches successively vary so that the two strands cannot be inadvertently joined when misaligned. Accordingly, when the teeth on one strand are positioned near or in their designated notches on the other, the zipper strands firmly adhere to close a garment opening. To open the zipper, a garment wearer simply pulls the tenuously-held zipper strands apart.
US10582732B2
A sleep apnea prevention sleep-aid mask is described. The sleep-aid mask is configured to secure the lips of a user together in a natural state, in order to encourage the respiratory system of the user to employ the nasal passages rather than the mouth for respiration. A pad equipped with a perforated mesh or channel is positioned over the lips and mouth of the user, and secured in position on the user via an adhesive, which temporarily affixes the pad to the face of the user. The sleep-aid mask is preferably shaped and sized according to the specific size of the user's face, and is configured to limit the effective diameter of the mouth of the user, in order to cause continued use of respiration via the nasal passages.
US10582729B2
An electronic vapor provision device comprising a power cell and a vaporizer, wherein the vaporizer comprises a heater and a heater support, wherein the heater is one the inside of the heater support.
US10582725B2
The present disclosure relates to an exemplary battery assembly for an electronic cigarette. The battery assembly includes a housing, a battery received in the housing, an AAES electrically connected with the battery, an end cover fixed at one end of the housing, and a holder. The end cover defines a receiving space. The holder includes a bottom wall, a side wall, and a plurality of spaced protruding stages. The side wall extends from a first surface of the bottom wall. The protruding stages are formed on an opposite second surface of the bottom wall. The side wall and the bottom wall cooperatively define an accommodating space. The AAES is received in the accommodating space in such a manner that the protruding stages face the battery. The holder is received in the receiving space.
US10582720B2
A coated foodstuff is made using two starch components. One is a spray cooked agglomerated waxy corn starch as having a peak time to hydration viscosity of between about 5.5 and about 7.5 minutes. The snack has unique expansion and hardness properties compared to coatings made from other corn starches, in embodiments the snack has a coating that expands to between about 1.7 and about 2.6 mm, a hardness of between about 3000 and about 3750 grams, or a hardness-to-expansion ratio of about 1200:1 to about 2200:1 g/mm.
US10582716B1
Provided herein are compositions (e.g., pharmaceutical compositions, nutraceutical compositions, foods, beverages, cosmetic compositions, diet supplements) comprising deuterated caffeine. The provided compositions may be useful for treating and/or preventing various diseases and conditions, such as obesity, causing weight loss, increasing metabolic rate, reducing appetite, increasing energy expenditure, increasing urine output, increasing sodium excretion, reducing edema, a pain disorder, apnea, hypotension, an encephalopathy, a neurological or psychiatric disorder, and an inflammatory disorder.
US10582713B2
A rapid method to detect and/or remove mobile insects inside granular material is presented. The core of this method is to heat grain samples to the desired temperatures (about 55 C) using microwave or radio frequency energy to force insects to move out of the granular material.
US10582711B2
A method for imparting to an article or product antimicrobial activity includes a step of applying an antimicrobial agent containing an antimicrobial polyaminosilane to the article or product. The antimicrobial polyaminosilane is prepared by subjecting an aminosilane monomer to a hydrolysis and condensation reaction. The antimicrobial polyaminosilane thus prepared is free of halide ions.
US10582709B2
Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R3, R4, R5, Q1, Q2, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
US10582704B2
The tree stand and climbing stick system of an embodiment of the present invention allows for a user to assemble sticks, install onto a tree, then use a swing-arm on the sticks, as an improved means for safely and securely installing your tree stand while in the tree. The stand has a simple female receiver which installs on a male fitting on the swing-arm. Once installed on the swing-arm, the user can then have both hands free to connect the straps to the tree. No one has used climbing sticks as a method to improve the user experience for hanging a lock on tree stand.
US10582703B2
The present disclosure is directed to methods and apparatuses for embedding a scent in a fishing lure. In a general example embodiment, a device for adding a scent to a fishing lure includes a body including an inner space configured to be isolated from an outside environment and a container for a scented liquid, an attachment mechanism configured to suspend the fishing lure within the inner space of the body, a heating mechanism configured to raise the temperature of the scented liquid to create steam, and a control unit configured to cause at least one of: (i) a pressurization mechanism to increase pressure within the inner space to cause the steam to add a scent to the fishing lure; or (ii) a charge to be applied to the fishing lure to cause the steam to add the scent to the fishing lure.
US10582697B2
A washable, reusable mat that serves as a stimulation device for animals, the mat having a base a base with a pile thereon, the pile being formed from a plurality of fingers which are arranged to form a structure with a plurality of spaces. Food or treats for the animal (e.g., a dog), are placed on the mat, and the food or treats fall among the fingers and are captured within the spaces formed in the pile by the fingers. The animal locates the food or treats by employing the animal's olfactory senses, such as smell and taste, to locate the food within the matt pile. The animal may use its nose (or paws) to gain access to the captured food by tunneling among the fingers, moving the fingers aside, or other action to access the hidden food.
US10582693B1
The dog kennel and sofa is a pet sofa (or pet bed) that may be reconfigured to form a kennel. In the pet sofa configuration, the dog kennel and sofa comprises a bottom panel, a rear panel, and two side panels, which are each padded to provide comfort for the pet that is at rest on the dog kennel and sofa. The dog kennel and sofa may be configured for use as a kennel by moving two hinged panels from a position behind the dog kennel and sofa to locations where they cover the top and front of the dog kennel and sofa. Clips may reinforce the joints where hinged panels meet. The front panel may have a door for insertion and removal of a pet. In some embodiments, a removable divider and second door may be provided to accommodate two pets.
US10582684B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH271387. The invention thus relates to the plants, seeds and tissue cultures of the variety CH271387, and to methods for producing a corn plant produced by crossing a corn plant of variety CH271387 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH271387.
US10582682B2
The present invention relates to a Lactuca sativa seed designated 45-268 RZ. The present invention also relates to a Lactuca sativa plant produced by growing the 45-268 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 45-268 RZ.
US10582681B2
New lettuce varieties designated ‘Bayfield’ and ‘Pueblo’ are described. ‘Bayfield’ and ‘Pueblo’ lettuce varieties exhibit stability and uniformity.