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发明授权
CN101229172B 甘草次酸30-酰胺类衍生物的固体分散物、其制备方法和用途 失效 - 权利终止

甘草次酸30-酰胺类衍生物的固体分散物、其制备方法和用途
摘要：
本发明公开了一种含甘草次酸30-酰胺衍生物类活性成分的固体分散物及其制备方法。固体分散物由活性成分、载体材料组成，其重量百分比为1∶0.5-1∶50，其制备方法可以采用熔融法、溶剂法、熔融-溶剂法、研磨法、喷雾干燥法、冷冻干燥法的一种。本发明的固体分散物可与一种或多种药学上可接受的载体、赋形剂或稀释剂形成药用组合物，用于抗炎、抗胃溃疡、抗结肠炎、镇痛、镇咳、保护肝脏等方面的治疗应用。
摘要（英）：

The invention discloses a solid dispersion containing glycyrrhetinic acid 30-amide derivative active component and a preparation method thereof. The solid dispersion consists of active components and carrier materials with the weight percentage of 1: 0.5 to 1: 50. The preparation method can adopt one of the following methods: melting method, solvent method, melting-solvent method, grinding method, spray drying method or freeze-drying method. The solid dispersion can form the medical combination with one or more pharmaceutical acceptable carriers, excipient or diluents; the invention is applied in treatments of anti-inflammatory, anti-gastric ulcer, anti-colitis, analgesia, anti-tussive, liver protection and so on.

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