The invention relates a guide rail, in particular to an ultra-precision near-zero friction guide rail, and aims to solve the problem that the friction force and drive system between the guide rail body of and the slide carriage of the current machine tool affect the precision of the linear movement between the slide carriage and the guide rail body. The slide carriage of the guide rail consists of an upper slide carriage, two lower slide carriages and two side slide carriages. A stator is arranged in a groove and fixed on the guide rail body through a connection seat. The upper end of a gear rack is fixedly connected with the lower end surface of the upper slide plate. The gear rack is meshed with a rotor. An upper throttle hole is provided in the corresponding position of the upper slide carriage to the guide rail body, and a side throttle hole is provided on the corresponding position of the side slide plate to the guide rail body. A lower throttle hole is provided in the corresponding position of the lower slide plate to the guide rail body. The guide rail uses a linear motor as the drive body to directly drive the slide carriage. The precision of the linear movement of the slide carriage can reach the nano level. The direct contact does not exist between the guide rail body and the slide carriage. The friction force between the guide rail body and the slide carriage is near zero, so the friction force between the guide rail body and the slide carriage is eliminated.