The invention discloses a murine prescription bait which comprises the following raw materials with the parts by weight: an adhesive ingredient: 31.9-35.9 parts of industrial paraffin wax with the melting point to be 60 DEG C; 62.9-69.9 parts of a mouse luring ingredient: the components of each part consist of 28-32% of rice flour, 64-68% of fine bran powder, 0.2-0.3% of common salt, 0.3-0.5% of saccharin, 0.8-1.1% of fish meal, 0.7-0.8% of medical tasteless mineral oil and 1.6-1.8% of a vomitory; an additional ingredient: 1.2-1.6 parts of benzoic acid and 0.1-0.3 part of blue pigment. The invention further discloses the application of the murine prescription bait used for preparing an anticoagulant raticide prescription poison bait. The murine prescription bait takes paraffin wax with the melting point to be 60 DEG C as the adhesive, which has higher palatability and longer lasting period than other wax baits; the murine prescription bait takes the rice flour and the fine bran powderas the main ingredients, which saves corn consumption to over 60% and has no impact on deratization effect.