The invention belongs to the field of medicament synthesis, and relates to a Danshensu derivative. The Danshensu derivative with a stable structure as above is obtained by combining Danshensu analogue and nitryl. By culturing primary rat cardiocytes, establishing a hypoxia model of cardiocytes and acute and chronic rat models of myocardial infarction, and performing pharmacological tests in vivo and in vitro, results show that the compound has good effect of protecting hypoxic cardiac muscle and certain anti-HIV activity. The compound can be taken as a pilot compound of original innovative medicaments for resisting myocardial ischemia to further prepare medicaments for treating ischemic heart disease and medicaments with anti-HIV activity.