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发明公开
CN101628893A 一类14-羟基青藤碱衍生物、合成方法及其用途 无效 - 撤回

一类14-羟基青藤碱衍生物、合成方法及其用途
摘要：
本发明公开一类14-羟基青藤碱衍生物，制备方法及其抗炎活性。本发明公开的青藤碱衍生物是以O-烃基和O-酰基青藤碱为原料，通过化学方法在14位发生氧化羟基化等反应制备的。本发明涉及的化合物在动物活体试验中表现出良好的抗炎活性，具有较好的应用前景。
摘要（英）：

The invention discloses 14-hydroxyl sinomenine derivatives, a preparation method thereof and anti-inflammatory activity thereof. The 14-hydroxyl sinomenine derivatives are prepared from the raw materials of O-alkyl sinomenine and O-acyl sinomenine by a chemical method that reactions such as oxidation and hydroxylation are carried out at a 14-position. The compounds of the invention show excellent anti-inflammatory activity in in-vivo tests of animals and have an excellent application prospect.

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