The invention relates to an ointment medicament for treating acne. The ointment medicament is prepared by mixing 128 to 160 grams of metronidazole, 12 to 15 grams of erythromycin, 4 to 5 grams of vitamin B6 and an oil phase substrate and a water phase substrate, wherein the oil phase substrate consists of 120 to 200 grams of stearic acid, 50 to 100 grams of glyceryl monostearate, 0 to 200 grams of liquid paraffin and 0 to 200 grams of castor oil; the water phase substrate consists of 320 to 450 grams of distilled water, 100 to 200 grams of glycerin, 2 to 15 milliliters of triethanolamine, 1.5 to 2 grams of lauryl sodium sulfate and 0 to 50 grams of stearyl alcohol; the metronidazole has the effect of resisting broad-spectrum anaerobion; metabolites generated when the metronidazole is reduced in a human body also have the effect of resisting anaerobion; antimicrobial spectrum of the erythromycin is similar to that of penicillin; and the vitamin B6 in an erythrocyte is pyridoxal phosphate which is used as a coenzyme indispensable to an organism, can participate in normal metabolism of amino acid, carbohydrate and fat, can also participate in the reaction of converting nicotinic acid into 5-hydroxytryptamine by tryptophan, can stimulate the growth of leukocytes, and is a substance needed for forming ferrohemoglobin.