The invention discloses a method for measuring the impurity content in a thallium bromide material, which is characterized by comprising the following steps: firstly, using TlBr as a raw material to prepare mother solution of Tl(III), wherein the content of the Tl(III) in the mother solution is 1 to 3 mg/mL; secondly, based on 1 mL of the mother solution, adding 10 mL of HBr with the concentration of 3.6 to 8.1 mol/L and 10 to 35 mL of isopropyl ether into 1 mL of the mother solution, oscillating the mixture uniformly, and standing and demixing the mixture to separate out a water phase; and thirdly, measuring the content of each impurity in the water phase by using an inductively coupled plasma mass spectrograph. The method can ensure that the content of a matrix element thallium in the thallium bromide material meets testing requirements of ICP-MS, and detect the content of each impurity of the material.