The invention provides a zoledronic acid composition for injection. The zoledronic acid composition for injection is prepared by the following steps of: 1) preparing medicinal liquid, namely selecting zoledronic acid and trisodium citrate as raw materials according to the weight ratio of the zoledronic acid to the trisodium citrate of 1:0.5-2, weighing a proper amount of the raw materials and placing the raw materials into a preparation tank, adding water for injection until the weight of the solution is 250 to 1,250 times that of the zoledronic acid, stirring the solution to dissolve the raw materials and mixing the raw materials uniformly and adjusting the pH value of the solution to be 4.0 to 6.0; 2) performing active carbon finishing; 3) performing adsorption; 4) performing aseptic filtration and subpackaging; and 5) performing vacuum freeze drying to obtain the zoledronic acid composition for injection. By the zoledronic acid composition for injection and the preparation method thereof, for injection of which the clarity is influenced by active carbon greatly, such as the zoledronic acid and the like, the heat source, the clarity and insoluble particles of the product can meet the requirements of the injection.