The invention relates to a system and method for generating physiological restriction of skeletal joints of cartoon characters. The system comprises a skeletal animation producing module, a skeletal animation screening module, a skeletal animation analyzing module and a skeletal joint restricting database, wherein the skeletal animation producing module is used for producing each animation and generating a skeletal animation library; the skeletal animation screening module is used for screening animation in the skeletal animation library to form a selective skeletal animation library; the skeletal animation analyzing module is used for traversing the selective skeletal animation library, incrementally adding the range of activity of each joint and generating the restricted data of each joint; and the skeletal joint restricting database is used for recording the restriction information of each skeletal joint. The method has the following beneficial effects: (1) the method has the characteristic of automation; an action library responding to the body type can be generated in the presence of sufficient skeletal animation libraries (the condition is easy to satisfy for many companies with many animation industries) without manual intervention; and (2) the method has the characteristics of extensibility and incremental improvement; as the skeletal animation entering into the library has more action types and better quality, the generated restriction of skeletal joints is more comprehensive and the effect is better.