The invention relates to a novel method for detecting sewage in an anti-skidding region at the bottom of a glass bottle, comprising the following steps of: positioning a center circular region of an obtained bottle bottom image, determining a bottle bottom anti-skidding region, determining a pixel of the anti-skidding region, carrying out opening and closing operation on the anti-skidding region and dividing the anti-skidding region into cells, solving a threshold of each cell by adopting an OSTU method in each processed cell, respectively carrying out binaryzation on each cell according to the obtained final threshold of each cell to obtain a final processing image of the anti-skidding region, carrying out statistics summation on points with pixel values of 0 on an image obtained by processing the anti-skidding region, setting a threshold, and when the value obtained through the statistics summation is more than the threshold, judging that the anti-skidding region has dirt or defects, otherwise, passing the detection.