The invention discloses a paper-based microfluid switch with an acoustic surface wave as an energy source. A paraffin micro-heating unit is arranged on a hydrophobic layer of a piezoelectric substrate, wherein the paraffin micro-heating unit comprises a PDMS (polydimethylsiloxane) microgroove, a PDMS fixing sheet which is connected to the top of the PDMS microgroove, and a metal microcell which is suspended inside the PDMS microgroove; and the bottom of the PDMS microgroove is tightly adhered and connected to the hydrophobic layer. By adopting the structure, the acoustic surface wave excited by an interdigital transducer on the piezoelectric substrate radiates a glycerine microfluid inside the PDMS microgroove, the temperature of the glycerine microfluid rises, the glycerine microfluid heats solid paraffin therein through the metal microcell with good heat-conducting property, the paraffin is expanded by heat, one end of a plastic foil above a micropore of a thin copper sheet ascends, and the plastic foil drives a third paper-based microchannel to ascend to enable the third paper-based microchannel to contact a first paper-based microchannel and a second paper-based microchannel respectively; and in the way that a switch is controlled to be switched on and off by virtue of expansion caused by heat and contraction caused by cold, the programmable characteristic of the switch is realized.