The invention discloses a processing method of a high depth-width ratio microstructure of optical glass, which is characterized in that the method adopts a high-precision optical glass as a research object, on the basis of a machining method for manufacturing different creasing shapes and creasing array patterns with pressing head microhardness testers of different shapes, combines with a wet method corrosion process, and carries out corrosions with different time intervals on a sample by using BOE solution (a mixture of HF and NH4F solution), thereby manufacturing high-precision optical glass structures of different shapes and different high depth-width ratio structures.