The invention relates to a multi-objective optimization method for collaborative allocation of time slots of multi-runway approaching-departing flights, belonging to the technical field of civil aviation. The multi-objective optimization method is mainly based on a collaborative decision-making idea and comprises the following steps of: firstly, dividing a time interval into a plurality of time slots, determining the approaching-departing capacity of an airport and dynamically creating time slots; secondly, establishing a multi-objective optimization model with minimum total delay cost, fair delay loss of each aviation company and balanced use frequency of each runway as objectives and with the effectiveness and the approaching-departing capacity of the airport as constraining conditions; and finally, solving by using a genetic algorithm to obtain an optimal flight time slot allocation scheme. The multi-objective optimization method disclosed by the invention is suitable for solving the time slot allocation problem of the approaching-departing flights of each airport.